Mustela nigripes (black-footed ferret): 132024470 Help Entry 132024470         CDS       T09425                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp04064   NF-kappa B signaling pathway mnp04066   HIF-1 signaling pathway mnp04145   Phagosome mnp04151   PI3K-Akt signaling pathway mnp04217   Necroptosis mnp04613   Neutrophil extracellular trap formation mnp04620   Toll-like receptor signaling pathway mnp04621   NOD-like receptor signaling pathway mnp04936   Alcoholic liver disease mnp05132   Salmonella infection mnp05133   Pertussis mnp05134   Legionellosis mnp05135   Yersinia infection mnp05140   Leishmaniasis mnp05142   Chagas disease mnp05144   Malaria mnp05145   Toxoplasmosis mnp05146   Amoebiasis mnp05152   Tuberculosis mnp05161   Hepatitis B mnp05162   Measles mnp05164   Influenza A mnp05170   Human immunodeficiency virus 1 infection mnp05171   Coronavirus disease - COVID-19 mnp05205   Proteoglycans in cancer mnp05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mnp05321   Inflammatory bowel disease mnp05323   Rheumatoid arthritis mnp05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mnp00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     132024470 (TLR4)    04066 HIF-1 signaling pathway     132024470 (TLR4)    04151 PI3K-Akt signaling pathway     132024470 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     132024470 (TLR4)   09143 Cell growth and death    04217 Necroptosis     132024470 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     132024470 (TLR4)    04620 Toll-like receptor signaling pathway     132024470 (TLR4)    04621 NOD-like receptor signaling pathway     132024470 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     132024470 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     132024470 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     132024470 (TLR4)    05161 Hepatitis B     132024470 (TLR4)    05171 Coronavirus disease - COVID-19     132024470 (TLR4)    05164 Influenza A     132024470 (TLR4)    05162 Measles     132024470 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     132024470 (TLR4)    05135 Yersinia infection     132024470 (TLR4)    05133 Pertussis     132024470 (TLR4)    05134 Legionellosis     132024470 (TLR4)    05152 Tuberculosis     132024470 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     132024470 (TLR4)    05144 Malaria     132024470 (TLR4)    05145 Toxoplasmosis     132024470 (TLR4)    05140 Leishmaniasis     132024470 (TLR4)    05142 Chagas disease     132024470 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     132024470 (TLR4)    05321 Inflammatory bowel disease     132024470 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     132024470 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     132024470 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mnp04131]     132024470 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:mnp04054]     132024470 (TLR4)    04090 CD molecules [BR:mnp04090]     132024470 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:mnp00536]     132024470 (TLR4) Membrane trafficking [BR:mnp04131]  Endocytosis   Phagocytosis    Toll-like receptors     132024470 (TLR4) Pattern recognition receptors [BR:mnp04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    132024470 (TLR4) CD molecules [BR:mnp04090]  Proteins   132024470 (TLR4) Glycosaminoglycan binding proteins [BR:mnp00536]  Hyaluronan   Cell surface receptors    132024470 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_5 LRR_9 LRR_Zer-1 LRR_NXF1-5 ThsB_TIR Pentapeptide_4 LRR_R13L1-DRL21 Motif Other DBs NCBI-GeneID:  132024470 NCBI-ProteinID:  XP_059266914 LinkDB All DBs Position 9:complement(16268670..16281493) Genome browser AA seq 833 aa AA seqDB search MMSPTRLAGMLIPAMAFLSCLRTESWEPCVQVVPNITYKCTELNLNKIPNNIPTSTKKLD LSFNPLRHLGNHSFSNFPELQVLDLSRCEIETIENDTYQGLNHLSILILTGNPIQKFSTA VFSGLSSLQTLVAVETNLQSLEDLPIEYLKNLKVLNVAHNLIRSFKLPEYFSNMTNLEYL DLSNNKIKVIYHSDLQVLHQMPLLNLSLDLSLNPLSFIQPGAFKEIKLHELTLRSNFDST DVMKTCIQGLAGLKIHHLVLGEFKNERNLESFDEYLLEGLCNVTIEKFRIAFFDEFSEDI TDLFNCLANVSTISLVHLFLKRPRYLPKNLRWQRLEMVNCEFEEFPKWELDSLKEFVFTA NKGVSTFTQMKLESLEFLDLSRNDLSFKGCCSYTDLGTTRLKHLDLSFNDIITMSSNFLG LEQLEYLDFQHSTLKQGSDFSVFLSLRNLRYLDISYTHTQVVFKGIFDGLVSLQVLKMAG NSFQDNFLPNIFKDLTNLTILDLSKCQLEGVSQTAFGSLPKLQLINMSHNNLLSLDTLPY EPLPSLQILDCSFNRIVASTEQVRQHFPSNLVSLNLTRNDFACVCEHQNFLQWVKDHRQL LVKVEEMVCTKPLDMQDTPLLSFRNATCQRSKTIITVSVFTVLMVSLVAVLVYKFYFHLM LLAGCKKYSRGESTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIA ANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKSLL RQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKPWSPEETADAENN NT seq 2502 nt NT seq  +upstreamnt  +downstreamnt atgatgtctcctacccgcctggctgggatgctgatcccagccatggccttcctctcctgc ctgagaaccgagagctgggagccttgtgtgcaggtggttcctaacattacttacaaatgc acggagctgaatctcaacaaaattcccaacaacattcctacatcaaccaagaaactggac ctgagctttaatcccctgaggcatttaggcaaccatagcttctccaacttccccgaacta caggtgttggatttatccaggtgtgaaattgagaccatcgaaaatgacacgtatcagggc ctaaaccacctctccatcttgatattgacaggaaaccctatccagaagttttccacagca gtcttttctggactctcaagtttacagactctggtggccgtggagacaaatctacagtct ctagaggaccttcccattgaatatctcaaaaacttgaaggtgcttaacgtggctcacaat cttatccgctccttcaagttacctgaatatttttctaacatgaccaacctggagtacttg gatctttccaataacaagatcaaagttatttatcatagtgacttgcaggttctacatcaa atgcctctactcaacctttctttagacttgtccctgaaccctttatcctttatccaacca ggtgcctttaaagaaattaaactgcatgaactgactttgagaagtaattttgatagtaca gatgtaatgaaaacttgtattcaaggtctggctggtttaaagatccatcacttggttctg ggagaatttaaaaatgaaaggaacttggaaagctttgacgaatatctcctggagggactg tgcaatgtgaccattgaaaaattccggatagcattctttgatgagttctcagaggatatc actgacttgtttaattgtttggcaaatgtttctacaatttccctggtgcatctgttttta aagagaccacgataccttcctaaaaatctcagatggcaacggctggaaatggttaactgt gaatttgaagaatttcccaaatgggagctggactctctcaaggagtttgttttcactgcc aacaaaggcgtgagcacttttactcagatgaagctggaaagtcttgagtttctagatctc agtagaaatgacctgagtttcaagggttgctgttcttacactgacttggggacaaccaga ctgaagcatttagatctgagcttcaatgatattattaccatgagttctaacttcttgggc ttagaacagctagaatatctagatttccagcattccaccctgaaacagggcagtgacttt tcagtattcctatccctcagaaacctccgttaccttgatatttcttatactcacacccaa gttgtcttcaaaggcatttttgatggcttggtcagcctccaagtcttgaaaatggctggc aattcttttcaggacaactttcttccaaatattttcaaagacctgacgaacttgaccatt ctagacctctctaagtgtcagctggaaggggtgtcccagacagcatttggctcgcttcct aaacttcagttgataaatatgagtcacaacaacctcttgtcattggatacactcccttat gagcctctcccctctctccaaattctggattgcagttttaatcgaatagtggcctccaca gagcaagtacgacagcatttcccaagtaatctagtttccttaaatcttactcggaatgac tttgcttgtgtttgtgaacaccagaatttcctacagtgggtcaaggaccacaggcagctc ttggtgaaagtggaagaaatggtgtgtaccaaacctttagacatgcaggacacgcccctg ctgagttttaggaatgccacctgtcagaggagcaagactatcataactgtgtcggtgttc actgtactcatggtttccttggtagcagttttggtgtataagttctatttccacctgatg cttcttgctggttgcaaaaagtacagcagaggtgaaagcacctacgatgccttcgttatc tactcaagccaggatgaagactgggtgaggaatgaactagtaaagaacttggaggagggg gtgcctccctttcagctctgccttcactacagagactttatccctggtgtggccatcgcc gccaatatcatccaggaagggttccacaaaagccggaaggttatcgttgtggtgtcccaa cacttcatccagagccgatggtgcatctttgagtatgagattgcccagacctggcagttt cttagcagtcgtgccggcatcatcttcattgtcctgcagaaggtggagaagtccctgctg cggcagcaggtggagctgtatcgcctcctcagcaggaacacttacctggagtgggaagac agtgtgctgggccggcatatcttctggagacgactccgaaaagccttgctggatggtaaa ccatggagtccagaagaaacggcggatgcagaaaacaactag

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