Mustela nigripes (black-footed ferret): 132025139
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Entry
132025139 CDS
T09425
Name
(RefSeq) LOW QUALITY PROTEIN: bifunctional purine biosynthesis protein ATIC-like
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00230
Purine metabolism
mnp00670
One carbon pool by folate
mnp01100
Metabolic pathways
mnp01523
Antifolate resistance
Module
mnp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132025139
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
132025139
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
132025139
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mnp04147
]
132025139
Enzymes [BR:
mnp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
132025139
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
132025139
Exosome [BR:
mnp04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
132025139
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
132025139
NCBI-ProteinID:
XP_059268283
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Position
9:61861393..61863324
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AA seq
590 aa
AA seq
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MAPSQLALFSVSDKTGLVEFARNLTSVGLHLIASGGTAKALREAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFSLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVSTEMQSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGASGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYNLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILSKKKKN
GNYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLSESALRDLI
VATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFK
TGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVDKLSEVSLSSD
AFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACNELGIILXLRLFHH
NT seq
1773 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacctgacttctgttggtttgcatctgatcgcctctggagggactgcgaaagct
ctgagggaggcgggcctggcagtcagagatgtctctgagctgacgggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgccgtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggccagacttgatttcagtcttataagagttgtcgtc
tgcaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggcggagtaaccctactgagagcagcagccaaaaaccatgct
cgggtgacagtagtatgtgaacccgaggactatgcagctgtgtccacagagatgcagagc
tccgacagcaaagacacctccttggagaccagacgtcagttagccttgaaggccttcact
catacggcacaatatgatgaagcaatttcagattacttcaggagacagtatagtaaagga
atatctcagatgcctttgaggtatggaatgaaccctcatcagactcctgcccagttatac
acgctgaagcccaagcttcccatcacagttctaaatggagcctctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcaaagaagctttaggcattcca
gctgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcagt
gaagacgaggccaaagtctgcatggtctataatctgtataaaacgcttacacccatatca
actgcatatgcaagagcaagaggggctgataggatgtcttcatttggtgactttgttgca
ttatctgatgtttgtgatgttcctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgaagatgaagctttgaaaatactttctaaaaaaaaaaaaaat
ggaaactactgtgttcttcagatggatcagtcctacaatccagatgaaaacgaagttcga
actctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaggtcatta
tttagcaacgttgtgaccaagaataaagatttgtcagagtctgcgctcagagacctcatt
gtagccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggt
caggttattggcattggagcaggacagcagtctcgaatacactgcacacgccttgcaggg
gataaagcaaattattggtggcttagacatcatccacaagtcctttcaatgaagtttaaa
actggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccatt
ggcgaggatgaggatttgataaagtggaaggcattgtttgaagaagtgcctgaattatta
actgaagcagagaagaaggaatgggttgacaaacttagtgaagtttctctcagctctgat
gccttctttcctttcagggataatgtagacagagctaaaaggagcggtgtggcctacatt
gctgctccttctggttctgctgctgacaaagttgtgattgaggcttgcaatgaattggga
ataatccttnngcttcggctctttcatcactga
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