Mustela nigripes (black-footed ferret): 132026153
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Entry
132026153 CDS
T09425
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04010
MAPK signaling pathway
mnp04020
Calcium signaling pathway
mnp04022
cGMP-PKG signaling pathway
mnp04024
cAMP signaling pathway
mnp04260
Cardiac muscle contraction
mnp04261
Adrenergic signaling in cardiomyocytes
mnp04270
Vascular smooth muscle contraction
mnp04723
Retrograde endocannabinoid signaling
mnp04725
Cholinergic synapse
mnp04726
Serotonergic synapse
mnp04727
GABAergic synapse
mnp04911
Insulin secretion
mnp04912
GnRH signaling pathway
mnp04921
Oxytocin signaling pathway
mnp04924
Renin secretion
mnp04925
Aldosterone synthesis and secretion
mnp04927
Cortisol synthesis and secretion
mnp04929
GnRH secretion
mnp04934
Cushing syndrome
mnp04935
Growth hormone synthesis, secretion and action
mnp05010
Alzheimer disease
mnp05020
Prion disease
mnp05022
Pathways of neurodegeneration - multiple diseases
mnp05207
Chemical carcinogenesis - receptor activation
mnp05410
Hypertrophic cardiomyopathy
mnp05412
Arrhythmogenic right ventricular cardiomyopathy
mnp05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132026153 (CACNA1S)
04020 Calcium signaling pathway
132026153 (CACNA1S)
04024 cAMP signaling pathway
132026153 (CACNA1S)
04022 cGMP-PKG signaling pathway
132026153 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
132026153 (CACNA1S)
04929 GnRH secretion
132026153 (CACNA1S)
04912 GnRH signaling pathway
132026153 (CACNA1S)
04921 Oxytocin signaling pathway
132026153 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
132026153 (CACNA1S)
04924 Renin secretion
132026153 (CACNA1S)
04925 Aldosterone synthesis and secretion
132026153 (CACNA1S)
04927 Cortisol synthesis and secretion
132026153 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
132026153 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
132026153 (CACNA1S)
04270 Vascular smooth muscle contraction
132026153 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
132026153 (CACNA1S)
04725 Cholinergic synapse
132026153 (CACNA1S)
04726 Serotonergic synapse
132026153 (CACNA1S)
04723 Retrograde endocannabinoid signaling
132026153 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
132026153 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
132026153 (CACNA1S)
05020 Prion disease
132026153 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
132026153 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
132026153 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
132026153 (CACNA1S)
05414 Dilated cardiomyopathy
132026153 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
132026153 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mnp04040
]
132026153 (CACNA1S)
Ion channels [BR:
mnp04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
132026153 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
132026153
NCBI-ProteinID:
XP_059270057
LinkDB
All DBs
Position
10:complement(38916763..38983855)
Genome browser
AA seq
1873 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSKVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMSPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSMMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSVVAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEIKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDTGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDEFIITSGGLGLTSGAAGPQDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANIAYGNSNHSNRQV
FSNLHYEREFPEETETPAARGGAFGQPRRVLGPHSKSCVEKLKEQLTQRETPKSQASPAP
CQRASAEPPLPEERRRPSPVSPPEQASHSSRTKDSRSQCQTPATAQLIQEALVRGGLDTL
AADANFVMATGQALADACQMAPEDMEVAATELLKRQESPEGLARARGRWSLRSSLGSLDQ
HQGSQETLIPPRL
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgagggtctgaggaagaaacagcccaagaagccggtt
ccggagattctgccaaggccgccccgggccttgttctgcttgaccctccagaaccccctg
aggaaggcctgcatcaacatcgtggaatggaaaccctttgagaccatcatcttgctcacc
atctttgccaactgtgtggcgctggctgtgtacctgcccatgccagaagatgacaacaac
actctgaaccttggcctggagaagctggagtatttcttcctcattgttttctcgatcgaa
gccgccatgaagatcattgcctacggcttcctattccatcaggatgcctacctgcgcagt
ggctggaacgtgctagacttcatcattgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacacagccccgatgagcagcaaaggggctggtctggac
gtcaaggccctgagagccttccgcgtgctcagacccctccggctagtgtccggggtgcca
agcctgcaggtggtcctcaattccatcttcaaggccatgctgcccctgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctacgccatcatcgggctggagctcttcaaaggc
aagatgcataagacctgctacttcatcgggacagatatcgtggccacggtggagaacgag
aagccctcaccctgcgccaggacaggatcggggcgcccgtgcaccatcaatggtagtgag
tgtcggggcggctggccggggcccaaccatggcatcacccacttcgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgttctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctactttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccagaggaaccttccaaaagctccgggagaagcagcagctggag
gaggacctgcggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagttgtctttggatgaaggaggctctgacacagagagcttgtatgaa
atcgagggcttgaacaaaatcattcagtttgttcgccactggaggcagtggaaccgcatc
tttcgctggaagtgccatgacgtgatcaagtccaaagtcttctactggctggtgatcctg
gtcgtagccctcaataccctgtctattgcctccgagcaccacaaccagcctctgtggctg
acccacttgcaagatgtagccaaccgcgtgctgctggccctcttcaccatcgagatgctg
atgaagatgtacgggctgggtctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagatcctgctagtggaatcgggtgctatgagc
cccctgggcatctccgtgctgcgctgtatccgcctcctcaggatcttcaagatcaccaag
tactggacatctctaagcaacctggtggcgtccctgctcaactccatccgctccatcgcc
tcactgctgctgctgctcttcctcttcatcatcatcttcgcgctgctgggcatgcagctc
ttcgggggcagatacgacttcgaggacacggaggtgcggcgcagcaacttcgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctgaccggtgaagactggaactccatgatg
tacaacgggatcatggcctacgggggaccgtcctaccccggggtgctcgtgtgtatttat
ttcatcatccttttcgtctgtggcaattatatcctgctcaatgtcttcctggccatcgct
gtggacaacctggctgaggccgagagcctgacttctgcccagaaggccaaagctgaggag
agaaagcgcagaaagatgtccaagggtctcccagacaagtcagaggaggagaagtcagtg
gtggccaagaagctggaacagaaacccaagggcgagggcatccctaccaccgccaagctg
aaaatcgatgagtttgaatctaacgtcaatgaaataaaggatccttacccttcggctgac
ttcccaggcgatgatgaagaagatgagcctgagatccctgtgagcccccgaccacgcccc
ctggctgagctgcagctgaaagagaaagcggtacccattccagaagccagctccttcttc
atcttcagccccaccaacaagatccgtgtcctgtgtcaccgcattgtcaatgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgccgccctggccgccgaggac
cccattcgggccgagtctgtgaggaatcagatccttgggtattttgacattgcattcacc
tcggtcttcactgtagagattgtcctcaagatgacgacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccgacccctccgggccatcaacagagccaaagggctgaagcacgtggtgcagtgc
gtgtttgtggccatccgcaccatcgggaatatcgtcctggtcaccacgctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagagaaggagtgcagaggctattactacgtgtacaaggacggagacccc
acgcagatggagctgcgcccacgccagtgggtacacagtgatttccactttgacaacgtg
ctctcggccatgatgtcactcttcacagtctccacctttgagggatggcctcagctactt
taccaggccatagactcatacaaggaggacacgggccccatctacaacaacagagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgtcattgtcaccttccaggagcagggagagacggagtacaagaactgtgag
ctggacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccgcccactgaggtgc
tatatccccaagaacccgtaccagtatcaggtgtggtatgtcgtcacctcgtcctacttc
gagtatctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcggaggagatgaaccacatctcagacatcctcaatgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggtgac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagt
gaaatcgacgagttcataattacttctggaggtttgggactgacctctggggctgctggc
ccgcaggacccggacgagagcgcccgtatctccagcgccttctttcgcctgttccgagtc
atgaggctgatcaagctgctgagccgggcggagggagttcgcactctgctgtggaccttc
atcaagtccttccaggccctgccctacgtggccctcctcatcgtcatgctcttcttcatc
tatgcggtcatcggcatgcagatgtttggtaagatcgccatggtggacgggacccagata
aaccgcaacaacaacttccagaccttcccgcaagctgtgctgctgctcttcaggtgtgca
acaggcgaggcatggcaggagatcctgctggcctgcagctacggcaagttgtgcgacccc
gagtcagattatgccccgggtgaggagtacacgtgtggcaccaacttcgcctactactac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgttgctgtcatc
atggacaactttgactacctcacgcgggactggtccattctgggccctcatcacctggat
gagttcaaggccatttgggcagagtatgacccagaggctaagggcagaatcaaacacctg
gatgtggtgaccctgttgagacggatccagccccctctgggctttgggaagttctgtccc
caccgggtggcctgtaagcggctggtgggcatgaacatgcccttgaacagcgatggcacg
gtcaccttcaacgccaccctctttgccctggtccgcacggcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgtg
gggaagttctacgccacgtttctgatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcctaagaaggacaccatacagatccaggctggactgcgg
accattgaggaagaggccgctccagagatccgccgtactatctcaggagacctgacggca
gaagaggagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actggaggcctctttggacaggtggacaacttcctggaaaggaccaactccctgccccct
gtcatggccaaccagagacccctccagtttgctgagatagagatggaagagctggaatca
cctgtcttcttggaggatttccctcaagatccacgcaccaaccctctggctcatgccaat
accaacaatgccaacgccaacattgcctatggcaacagcaaccatagcaacaggcaggtg
ttttcaaacctccactatgaaagggagttccctgaagagacagagacgcctgctgccaga
ggaggagcctttggtcaaccccgaagggtcctgggaccccacagcaaatcctgtgtggaa
aagctaaaagaacagctgacccagagagaaacccccaaatcccaagcatctcctgcccct
tgccagcgtgccagcgccgagcctcccctgcctgaggagaggaggaggcccagcccggtg
tctccgcccgagcaagcatcccacagcagtaggaccaaggacagtagatcccagtgccag
actccagcgacagcccagctgattcaagaggctctggttcgaggtggcctggacaccttg
gcggctgatgctaactttgtcatggcgaccggccaggccctggcagatgcctgccagatg
gcaccagaggacatggaggtggcagccacagaactgctgaaaagacaagagtccccagag
ggcctggctagggcccggggacgctggagcctcaggtcctcgctgggcagccttgatcag
catcagggctcccaggagaccctgatcccccccaggctgtga
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integrated database retrieval system
