Mustela nigripes (black-footed ferret): 132026417
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Entry
132026417 CDS
T09425
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00010
Glycolysis / Gluconeogenesis
mnp00020
Citrate cycle (TCA cycle)
mnp00620
Pyruvate metabolism
mnp00785
Lipoic acid metabolism
mnp01100
Metabolic pathways
mnp01200
Carbon metabolism
mnp01210
2-Oxocarboxylic acid metabolism
mnp04066
HIF-1 signaling pathway
mnp04922
Glucagon signaling pathway
mnp05230
Central carbon metabolism in cancer
mnp05415
Diabetic cardiomyopathy
Module
mnp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
132026417 (PDHA2)
00020 Citrate cycle (TCA cycle)
132026417 (PDHA2)
00620 Pyruvate metabolism
132026417 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
132026417 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
132026417 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
132026417 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
132026417 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
132026417 (PDHA2)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
132026417 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
132026417
NCBI-ProteinID:
XP_059270287
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All DBs
Position
1:159650700..159651875
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AA seq
391 aa
AA seq
DB search
MKKILTATVSRVWSGVAQKPASRVLVASCNFSKDATFEIKKCDLYRLEEGPPDTTVLTRE
DGLKYYRMMQTIRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILAELTGRKGGCANGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGKNEVCLTLYGDGAANQGQIAEAYNMAALWKLPCVFICENNLYGMGTSAERAAAS
TDYYKRGNFIPGLRVDGMDVLCVREATRFAADYCRSEKGPIVMELLTYRYHGHSMSDPGV
SYRTRQEIQNVRSKSDPIMLLKNRMVDSKLATIEEFKEIDVEVRKEIDDAVHFATTDPEP
ALEELGHHIYCDNPPFEVRGTSQWIKFKSLP
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatactcaccgccacggtctcccgcgtgtggtctggggtggcccagaagccc
gctagcagagtgctcgtggcatcctgtaacttttcaaaagatgctacatttgaaattaag
aaatgtgacctttatcgattagaagagggtccccctgacacaacagtgctcacccgggag
gatgggcttaaatactacaggatgatgcagactattcgcagaatggaattgaaggccgat
cagctgtataaacaaaagttcattcgtgggttctgtcacttgtgcgatggtcaggaagct
tgctgcgtgggcctggaggctgggataaatcccacggatcatgtcatcacatcctacagg
gctcatggcttgtgctatactcgcggactttctgtccgatcaattctcgcagagctcaca
ggacggaagggaggctgtgctaacggaaagggagggtctatgcatatgtatgcaaagaac
ttctatgggggcaacggcatcgttggcgcccagggacccctaggagctggtgtcgccctg
gcctgtaaatataagggcaaaaatgaggtctgtttgactctctacggggatggtgctgcg
aatcagggccagatagccgaagcttacaatatggccgctttgtggaaattaccttgtgtt
ttcatctgtgagaataacctttatggaatgggcacctctgccgagagagcagcagccagc
actgattactacaagagaggaaattttatccctggactaagggtggatggaatggatgtt
ctatgtgttcgggaggcaactaggtttgcagctgactactgcagatctgaaaaggggccc
atagtgatggagctgctgacataccgttatcatggacacagcatgagtgaccctggagtg
agttatcgtacacgacaagaaattcagaatgtaagaagtaagagtgatcctattatgctc
ctcaaaaatagaatggtagacagtaagcttgccaccattgaagaattcaaggaaattgat
gtggaagtgaggaaagaaattgacgatgcagtccactttgctacaactgatcctgaacca
gctttggaggaattaggtcatcacatctactgcgataatccaccttttgaagttcgtggt
acaagtcagtggatcaagtttaagtctctcccttaa
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