Mustela nigripes (black-footed ferret): 132026779
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Entry
132026779 CDS
T09425
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04020
Calcium signaling pathway
mnp04022
cGMP-PKG signaling pathway
mnp04024
cAMP signaling pathway
mnp04148
Efferocytosis
mnp04260
Cardiac muscle contraction
mnp04261
Adrenergic signaling in cardiomyocytes
mnp04380
Osteoclast differentiation
mnp04919
Thyroid hormone signaling pathway
mnp04972
Pancreatic secretion
mnp05010
Alzheimer disease
mnp05017
Spinocerebellar ataxia
mnp05022
Pathways of neurodegeneration - multiple diseases
mnp05410
Hypertrophic cardiomyopathy
mnp05412
Arrhythmogenic right ventricular cardiomyopathy
mnp05414
Dilated cardiomyopathy
mnp05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
132026779 (ATP2A1)
04024 cAMP signaling pathway
132026779 (ATP2A1)
04022 cGMP-PKG signaling pathway
132026779 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132026779 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
132026779 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
132026779 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
132026779 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
132026779 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
132026779 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
132026779 (ATP2A1)
05017 Spinocerebellar ataxia
132026779 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
132026779 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
132026779 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
132026779 (ATP2A1)
05414 Dilated cardiomyopathy
132026779 (ATP2A1)
05415 Diabetic cardiomyopathy
132026779 (ATP2A1)
Enzymes [BR:
mnp01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
132026779 (ATP2A1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
132026779
NCBI-ProteinID:
XP_059271023
LinkDB
All DBs
Position
11:16943581..16958361
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AA seq
1000 aa
AA seq
DB search
MEAAHSKTTEECLAYFGVSETTGLSPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVAATGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGNVCVLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSALDFNETKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KDKIMSVIKEWGTGRDTLRCLALATRDSPPKREEMILDDSARFMEYETDLTFVGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVTDRAYTGREFDDL
PLAEQREACRRACCFARVEPSHKSKIVEFLQSYDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYADDGPQVTYNQLTHFMQCNEENPDFEGLDCEVFEAPEPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWVNIWLVGSICLSMSLHFLILYVDPLPMIFKLRA
LDLTQWLMVLKISFPVIGLDELLKFIARNYLEDPEDERRK
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagaccacagaagaatgtttggcctattttggggtgagcgag
actacaggccttagcccggaccaagtgaagcggcatctggagaaatacggccccaatgag
ctccctgctgaagaagggaagtccctgtgggagctggtggtagagcagtttgaagacctc
ctggtgcggatccttcttctggccgcctgcatctccttcgtgctggcctggttcgaggaa
ggcgaagagaccatcaccgcctttgtggaaccctttgtcatcctcctgatcctcattgct
aatgccatcgtgggcgtttggcaggagcgtaacgcagagaacgccatcgaggccctgaaa
gaatatgaacccgagatggggaaagtctaccgggctgaccgcaagtcagtacaaaggatc
aaggctcgggacattgtccccggggacatcgtggaggtggctgtgggggacaaagtcccc
gcggatatccgcatcctggccatcaaatccactacgctccgggttgaccagtccatcctg
acaggcgagtctgtatctgtcatcaagcacacagaccctgttcctgacccccgagctgtc
aaccaggataagaagaacatgcttttctcgggtaccaacattgccgctggcaaggccgta
ggcatcgtggccgccacgggtgtgagcaccgagattgggaagatccgtgaccaaatggcc
gccacggagcaggacaagacccccctgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgtgtggctgtctggctcatcaacattggccatttcaac
gatcctgtccacgggggctcctggttccggggggctatctactactttaagatcgccgtg
gccctggctgtggctgcgatcccagaaggccttcctgcggtcatcaccacctgcctggcc
ttgggcacccggcggatggcaaagaagaatgccattgtgaggagcctgccctccgtagag
actctgggctgcacctccgtcatctgttccgacaagacgggcaccctcaccaccaaccag
atgtctgtgtgcaagatgtttatcatcgacaaggtggacggaaacgtctgcgtcctgaac
gagttctccatcactggctccacttacgctccggaaggagaggtcctgaagaatgataag
cccgtccgcgcagggcagtatgatgggctggtggaactggccaccatctgtgccctctgc
aatgactccgccttggacttcaatgagaccaaaggtgtttacgagaaggtgggggaggcc
accgagacggcgctcaccaccctggtggagaagatgaatgtattcaacactgacgtgaga
agcctctcaaaggtggagagagccaatgcctgcaactcggtgatccgccagctaatgaag
aaggaattcaccctggagttctcccgggacaggaagtccatgtctgtctactgctcccca
gccaaatcccgggctgccgtgggcaacaagatgtttgttaagggtgcccctgagggggtc
attgaccgctgtaactacgtgcgagttggcaccacccgggtgcccatgacagggccggtg
aaggacaagatcatgtccgtgatcaaggagtggggcactggccgggacacgctgcgctgc
ctggccctggctacccgagacagccccccaaagcgagaagagatgatcctggatgactct
gccaggttcatggaatatgagacggacctgacgttcgtcggcgtggtgggcatgctggac
ccaccccgcaaggaggtcacaggatctattcagctgtgccgggacgccgggatccgagtc
atcatgatcactggggacaacaagggcacggccattgccatctgccggcgcatcggcatc
ttcggggagaacgaagaggtgacggaccgagcctacaccggccgggagttcgacgacctg
cccctggccgagcagcgggaggcctgccgccgtgcctgctgctttgcccgcgtggagccg
tcccacaagtccaagatcgtggagtttctgcagtcctacgatgagatcacagccatgaca
ggtgacggagtcaacgacgcgccggccctgaagaaggccgagatcggcatcgccatggga
tcgggcaccgccgtggccaagacggcgtccgagatggtgctggccgacgacaacttctcc
accatcgtggctgcggtggaggagggccgcgccatctacaacaacatgaagcagttcatc
cgctatctcatttcctccaacgtgggcgaggtggtctgcatcttcctgaccgccgccttg
gggctgcccgaggccctgatccccgtgcagctgctgtgggtgaacttggtgactgacggg
ctcccggccacagccctgggcttcaacccgccagacctggacatcatggaccggcccccc
cggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggcgattggg
ggctatgtgggtgcagccactgtgggagcggccgcctggtggttcttgtatgcagatgac
gggcctcaggtcacctacaaccagctgactcacttcatgcagtgcaacgaggaaaaccct
gacttcgagggcctggactgtgaggtctttgaggcccccgagcccatgaccatggccctg
tccgtgctggttaccatcgagatgtgcaacgctctcaacagcctgtccgagaaccagtcc
ctcctgcggatgcccccctgggtgaacatctggctggtgggctccatctgcctctccatg
tccctccacttcctcatcctctacgtcgaccctctgccgatgatcttcaagctccgggct
ctggacctcacccagtggctcatggtcctgaagatctcatttccagtcattgggctcgat
gagctcctcaagttcattgctcggaactacctggaggatcccgaagacgagagaaggaag
taa
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