Mustela nigripes (black-footed ferret): 132027018 Help Entry 132027018         CDS       T09425                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp04072   Phospholipase D signaling pathway mnp04115   p53 signaling pathway mnp04140   Autophagy - animal mnp04150   mTOR signaling pathway mnp04151   PI3K-Akt signaling pathway mnp04152   AMPK signaling pathway mnp04211   Longevity regulating pathway mnp04218   Cellular senescence mnp04714   Thermogenesis mnp04910   Insulin signaling pathway mnp04919   Thyroid hormone signaling pathway mnp05163   Human cytomegalovirus infection mnp05165   Human papillomavirus infection mnp05168   Herpes simplex virus 1 infection mnp05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mnp00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     132027018 (TSC2)    04151 PI3K-Akt signaling pathway     132027018 (TSC2)    04152 AMPK signaling pathway     132027018 (TSC2)    04150 mTOR signaling pathway     132027018 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     132027018 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     132027018 (TSC2)    04218 Cellular senescence     132027018 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     132027018 (TSC2)    04919 Thyroid hormone signaling pathway     132027018 (TSC2)   09149 Aging    04211 Longevity regulating pathway     132027018 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     132027018 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     132027018 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     132027018 (TSC2)    05163 Human cytomegalovirus infection     132027018 (TSC2)    05165 Human papillomavirus infection     132027018 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mnp01009]     132027018 (TSC2) Protein phosphatases and associated proteins [BR:mnp01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      132027018 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Motif Other DBs NCBI-GeneID:  132027018 NCBI-ProteinID:  XP_059271625 LinkDB All DBs Position 11:complement(37584140..37616284) Genome browser AA seq 1813 aa AA seqDB search MAKPTSKDSGLKEKFRNLLGLGTPRPNPRSAEGKQTEFIITADILRELSVECGINNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDHLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYKEDAALLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLTIMERLLQQLQSLDSPELRAVVHDLLTTVEELCDQSEFHGSPERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHVPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVMSRSLS PPAELEERDVAAYSASVEDVRTAVLGLLVILQTKLYSLPASHAMRVYETLVGHIQLHYKH DYTLPIAASIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDAMEPERGPEKKAS GTLSNPTGPPGPAPTGPAVRLGSLPYSLLFRVLLQCLKQEADWKVLKLVLGKLPESLRYK VLIFTSPCSVDQLSAALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARTPKQGLTNS PPVKECKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGGPELSTDAGVHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG TLDTPASHFAGGPTSPGAQTAPASKPERASAGTQFPAQEKTSLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS AKPPPPPRSNTVASLSSLCQSSCRAQLHRGVSWADSAVVPEEGSPSEARLPTEPTELEDF EATLGTDRRSGRAEAYSRSSSSSSQEERFPAEEPAAGGVPIERAVSSEGARPSAELPFQP CQPLSKSSSSPELQTLQDILGDPGDKTDVGRLSPEAKTRSQSGILDGAGAAWSAPGEESQ DRGPTQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVERDAFKSRTGASNTEKVPG INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSN SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITPL DYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY PSKWIARLRHIKRLRHRIQEEAQYSSPSLPLLQTHTPGHGKASAPAPAEPVPAYETGQRK RLISAVDDFTEFV NT seq 5442 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgacaagcaaagattcaggtctgaaggagaaattcaggaatctgttagga ctgggaaccccgaggccaaaccccaggtctgcagagggcaagcagacggagtttatcatc acggccgacatcctgagagaactgagtgtcgaatgtggtatcaacaatcgcatccgggtg atagggcagatctgcgaggttgccaaaacgaagaaatttgaagagcacgcggtggaggcg ctgtggaaggccgtggcagacctgctgcagccagagcggcccccggaggcccggcacgcg gtgctggctctgctgaaggccattgtgcaggggcagggggaccacctgggcgtgctcaga gccctcttcttcaaggtcatcaaggattacccttccaatgaagacctccacgagagactg gaagtgttcaaggccctcacggacaacgggagacacatcacctacttggaagaagaactg gctgggttcgtgctgcagtggatggacatcggcctgtcctcagaattcctcttggtgctt gtgaacttggtcaagttcaacagctgttacctggatgagtacattgcatcgatggtccac atgatctgcctgctgtgtgtccagacggtgtcgtccgtagacatagaggtgtccctgcag gtgctggacgccgtggtctgctacaactgcctgccggccgagagcctcccgctgttcatc gtcactctctgccgcaccatcaatgtcaaggagctctgtgagccttgctggaagctgatg cgtaacctcctgggcacccacctggggcacagtgccatctacaacatgtgtcggatcatg gaggacagagcctacaaggaggacgccgcgctgctgagaggcgccgtgttctttgtgggc atggcgctctggggcgcgcaccgactttactctctgaagaactccccgacatctgtgctc ccgtccttttatgaggccatgacctgtccgaacgaggtggtgtcctacgagattgtgctg tccataaccagactgatcaagaagtaccggcgggagctccaggccgtgacgtgggacatc ctgctgaccatcatggagcgcctgctgcagcagctccagagcctggacagcccagagctc agagccgtcgtccacgacctgctgaccacggtggaagagttatgcgatcagagcgagttc cacggctctccagagagatacttcgagctggttgagcgatgcgcagaccagaggcctgag tcctcgctcttgaacttaatcacgtacagggctcagtcgatccatccggccaaagacggc tggattcacaacctgcagctgctgatggagaggttcttcaggaatgagtcccgcagtgcc gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacagacagttctat gaggaggagctgatcagctcagtggtcatctcacaactctcccacgtcccagaggacaaa gacccccaagtccggaaactggccacccagctgctggtggacctggctgagggctgtcat acccaccacttcaacagcctgctggacattgtggaaaaggtgatgtcccgctccctttct ccacccgctgagctggaggagagagacgtggcggcgtactcggcctccgtggaggacgtg aggactgctgtcttggggctcctggtcatcctgcagaccaagctatactccttgcccgcc agccacgcgatgcgcgtttacgagacacttgttggccacatccagctgcactacaagcac gactacaccctgcccattgccgccagcatccggctacaggccttcgacttcctgctgctc ctgagggccgactcgctgcaccgtctcggcctgcccagcaaggatggggccgtgaggttc agcccttactgtgtttgcgatgccatggagccagagcggggtccagagaagaaggccagt ggcaccctgtccaatcccactgggccgcccggccctgcgcccacaggccccgcggtgaga cttggctctttgccttactccctgctcttccgtgtgctgctgcagtgcctgaagcaggag gcggactggaaggtactgaagctcgtgttgggcaagctgcccgagtccctgcgctacaag gtgctcatcttcacgtctccgtgcagcgttgaccagctgtccgctgccctctgctccatg ctttcaggtcccaggaccctggagcggctccgaggcaccccggaaggcttctccagaacc gacctgcatctggcagtggttcctgtgctgacagcactcatctcgtaccacaactacttg gacaaaaccagacagcgggagatggtgtactgcctggagcaaggcctcatctaccgctgt gccagccagtgcgtggtggcactggccatctgcagcgtggagatgccggacatcatcatc aaggcgcttcctgtgctggttgtgaagctcactcacatctcagccactgctagcatggcc gttcctctccttgagttcctgtcaactctggccaggctgcctcacctctacaggaacttt gcagcggagcagtacgcgagtgtctttgccatctccttgccttacaccaatccctccaag tttaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcattagatgc cgcctgcccttccggaaggattttgttccctttatcactaagggcctgcgctccaacgtt ctcctgtcctttgatgacacccccgagaaggacagcttcagagcgcgaagcaccagcctc aacgagaggcccaagagtttgaggatagccagaacccccaaacaaggcttgactaactct ccacccgtgaaagaatgcaaggagagctctgccgcagaggccttccggtgccgcagcatc agtgtgtcagagcatgtggtccgcagcaggatccagacgtccctcaccagcgccagtctg gggtctgcagacgagaattcaatggcccaggctgatgacaacttgaaaaatctccacctg gagctcacggagacatgtctggacatgatggccagatacgtgttctccaacttcacagcg gtccccaagaggtcccctgtgggagagttcctcctggctggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcaccgtgacaacgagtgtgggaaccgggacccggtcgctg ctgggtttggactcaggagagctgcagggaggcccagagttgagcactgacgctggtgtg cacgtgagacagaccaaggaggcgcctgccaagctagagtcccaggctgggcagcaggtg tgccgcggggccagggatcgcgtccgctccatgtccgggggccatggccttcgtgtgggt accctggacactccagcatcccacttcgcaggtggccccacttctcctggtgcacagacg gcaccagccagcaaacctgagagggcgtcagcgggcacccagttcccagcacaggagaag acgagcctggcggcctacgtgccccttctgacccagggctgggcagagatcctggtccgg aggcccacagggaacaccagttggctgatgagcctggaaaaccctctgagccccttctcc tcggacatcaacaacatgccgctgcaggagctgtccaatgcgctcatggccgctgagcgc ttcaaggagcgtcgggacacggccttgtacaagtcactgtcggtgccggcggctggctcg gccaagccccctccacccccgcgatccaacacggtggcctctctctcctcgctgtgccag tccagttgccgagcacagctgcacaggggcgtttcctgggcagactcagcggtcgttccg gaggaggggagtccgagcgaggctcgtttgcccactgaacccacagagttggaggacttt gaggcaacgctaggcacagaccggcgcagtggccgcgctgaggcttacagcaggtcatca tcaagctccagccaggaggagaggttccccgcggaggagcctgctgctggaggagtcccc atcgagcgggctgtctcttccgagggcgcccggccttctgcggagctccccttccagccc tgccagcccctcagcaagtccagctcctcgcccgagctgcagaccctacaggacatcctt ggggaccctggggacaagactgatgttggccggctgagccctgaggccaagacccggtcc cagtccgggatcctggacggggcaggtgccgcctggtcagccccaggtgaagagagccag gaccggggccccacgcagcccgagggtcccttgccttccagctgcccccgctcccccagt ggcctgcggcccagaggctacaccatctctgattcggccccgtcacgcagaggcaagagg gtagagagggatgccttcaagagcagaactggggcctccaataccgagaaggtacccggc atcaatcccagctttgtgttcctgcagctctaccattccccgttctttggtgacgaatcc aacaagcccatccttctccccaatgagtcctttgagcggtcagtgcagcttctcgaccag attccgtcctacgacacccacaagatcgctgtcctgtacgtgggagaaggccagagcaac agcgagctcgccatcttgtccaacgagcacggctcctacaggtacacggagttcctcacc ggcctgggcaaactcatcgagctcaaggactgtcagccagacaaggtgtacctgggcggc ctggatgtatgcggggaggacggccagttcacttactgctggcatgacgatatcatgcaa gcggtcttccacattgccactctgatgcccaccaaagatgtggacaagcaccgctgtgac aagaagcgccacctgggcaacgacttcgtgtccatcgtctacaatgactcgggcgaggac ttcaagctgggtaccatcagaggccagttcaactttgtccacgtgatcatcacccccctg gactacgaatgcaatctggtgtccctgcagtgcaggaaagacatggagggcctcgtggac accagcgtggccaagatcgtgtctgaccgcaacctgccttttgtggcccgtcagatggct ctgcacgcaaacatggcctcacaggtgcatcacagccgctccaaccccaccgacatctac ccctccaagtggattgccaggctccgtcacatcaagcgactccgccaccggatccaagag gaagcccagtactccagccctagcctgcccctgctgcagacgcacaccccgggccacggc aaagcatccgctccggcgcccgcggagcccgtgccggcgtacgagaccggccagcggaag cgcctcatctccgcggtggatgacttcacagagttcgtgtga

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