Methylobacterium organophilum: MMB17_10960
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Entry
MMB17_10960 CDS
T08093
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mog
Methylobacterium organophilum
Pathway
mog00300
Lysine biosynthesis
mog00550
Peptidoglycan biosynthesis
mog01100
Metabolic pathways
mog01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mog00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MMB17_10960
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MMB17_10960
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MMB17_10960
Enzymes [BR:
mog01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MMB17_10960
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UMY19772
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Position
2376691..2378154
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AA seq
487 aa
AA seq
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MTDAPLWTPAALAAATGGRLLGEARPVTGASIDTRSLQPGDLFFAIRGEARDGHDFVRDA
LAKGAGAAVVAETRAEEFAGAGPVLAVPGQGEDPVLDAMRALGRAARARSRAGIVAVTGS
VGKTGTKEALRHVLSAQGETHASIASYNNHWGVPLTLARMPESARYGVFEIGMNHAAEIV
PLSVQVRPQVALITTVEPVHIEHFPSLSAIADAKGEIFSGIEPGGVAVINRDNPNYERLL
AHARASRAGRVVSFGEHAEADVRAHRILTRPDVSVVDATVMGVPLAYQLGTPGRHVAMNS
LGVLAVVHALGADLARAALSLAGLKPPVGRGERTALLIGEGEAYLVDESYNANPASMRAA
MATLAGIDTPGKGRRIAVLGDMLELGAAAEAHHRELAEAVKANGIDLVFTAGGMMRHLFE
ALPVARRGLHAPTSAELTDAVVAALRPGDAVMVKGSNSIRMGRIVEAVKARYAVDPTLRA
AAMQRAP
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacgcccccctctggactccggccgccctcgcggcggcgaccggcggccgcctg
ctgggcgaggcacgcccggtcaccggcgcctcgatcgacacccgcagcctgcagccgggc
gacctgttcttcgcgatccgcggggaggcgcgcgacggccacgacttcgtgcgggacgcc
ctcgccaagggggccggcgccgccgtggtggccgagacccgcgcggaggaattcgccggg
gccggccccgtgctcgcggtgccggggcagggcgaggatccggtcctcgacgccatgcgc
gccctcggccgggccgcccgcgcccgcagccgggccggcatcgtcgcggtgacgggctcg
gtcggcaagaccggcaccaaggaggccctgcgccacgtgctctcggcacagggcgagacc
catgcctccatcgcctcctacaacaaccattggggcgtgccgctcaccctcgcccgcatg
ccggagagcgcccgctacggcgtgttcgagatcggcatgaaccacgccgccgagatcgtg
ccgctcagcgtccaggtgcgcccgcaggtggcgctgatcaccacggtcgagccggtccat
atcgagcatttcccctcgctctcggccattgccgacgccaagggcgagatcttctccggc
atcgagccgggcggcgtcgcggtgatcaaccgcgacaacccgaattacgagcgcctgctc
gcccatgcccgcgcctcccgcgccgggcgggtcgtcagcttcggcgagcatgcggaggcc
gatgtgcgggcccaccgcatcctgacccggcccgacgtctccgtggtcgacgccacggtg
atgggcgtgccgctggcctaccagctcggcaccccgggccggcacgtggcgatgaattcc
ctcggcgtgctcgccgtggtgcatgccctcggcgccgacctcgcccgcgccgccctgtcg
ctcgccgggctgaagcccccggtcgggcgcggcgagcgcacggctctgctgatcggggag
ggcgaggcctatctcgtcgacgagagctacaacgccaaccccgcctccatgcgcgcggcg
atggcgacgctcgccgggatcgacaccccgggcaagggccgccgcatcgctgtgctcggc
gacatgctggagctcggcgccgccgcggaggcccatcaccgggagctcgccgaggccgtg
aaggccaacggcatcgatctcgtcttcaccgccggcggcatgatgcgccacctgttcgag
gcgctgccggtggcccgtcgcggcctgcacgcgccgacctccgccgagctgaccgacgcc
gtggtcgccgccctgcgcccgggcgacgccgtgatggtgaagggctccaactcgatccgc
atgggccggattgtcgaggcggtgaaagcccgctacgcggtcgacccgaccctgcgggcc
gccgcgatgcagcgcgcgccctga
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