Methanothermococcus okinawensis: Metok_1352
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Entry
Metok_1352 CDS
T01534
Name
(GenBank) isopropylmalate/citramalate/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mok
Methanothermococcus okinawensis
Pathway
mok00290
Valine, leucine and isoleucine biosynthesis
mok00620
Pyruvate metabolism
mok01100
Metabolic pathways
mok01110
Biosynthesis of secondary metabolites
mok01210
2-Oxocarboxylic acid metabolism
mok01230
Biosynthesis of amino acids
Module
mok_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mok00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Metok_1352
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Metok_1352
Enzymes [BR:
mok01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Metok_1352
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
AEH07317
UniProt:
F8AJW1
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All DBs
Position
1394294..1395841
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AA seq
515 aa
AA seq
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MEPYSKTNNIIKNSINNLNLPKNVKIFDTTLRDGEQTPGVSLTPDEKVEIAINLNNIGVD
IIEAGFPISSHGEQEAIKKITSLNMNAEICGLARAVKKDIDVAIDCGVDSIHTFIATSPL
HREYKLKMSKEEIINRAVDAIEYIKEHGLKVEFSAEDATRTEIDYLIEVYKNAEDAGADR
INVPDTVGVMIPRAMTYLISQLKKEISIPISVHCHNDFGLAVANSLGAVEGGAQQVHCTV
NGLGERAGNAALEEVVMSLMMIYGIDTNINTEKLTEISNLVSKLTGINTQPNKAVVGENS
FAHESGIHAHGVLAHALTYEPIPPEIVGQKRKIILGKHTGAHAIQSKLKELGLEVGKNVS
EEQFKEIVNRIKDIGDKGKMITDADVIAIVEDITKRTIKSKRTVNLEQIAVMTGNKLIPT
ASVELIINNERYITSKVGVGPVDAALKAIQSVIGEKIKIKEYHINAITGGTDALAEVIVK
LEGYGKEITAKAANEDIVRASVEAIIDGINKIMDM
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atggagccttattctaaaaccaacaatataattaaaaattccattaataatctaaaccta
ccaaaaaatgtcaagatttttgatactacgctaagagatggagaacaaacacccggagta
tccttaaccccagatgaaaaggtagaaattgctataaacctaaataatataggcgtagat
attatagaagcaggatttcctatctcatcccatggagagcaggaagccattaaaaaaata
acatcactaaatatgaatgcagaaatttgcggtcttgcaagggctgttaaaaaagatata
gatgttgcaatagactgcggtgttgatagcatacatacatttatagcaacatccccactc
catagggaatataaattaaagatgagcaaagaagagataataaatagagcagtagatgcc
atagaatatataaaagaacatggattaaaagtagaattctcagcagaggatgccacaagg
acggaaattgattatctgatagaagtttataaaaacgcagaagatgcaggtgctgacaga
ataaatgttccagatactgttggagtgatgattccaagagcaatgacatatttaataagc
cagttaaaaaaggaaatctccattcctatttcagttcattgccataacgattttggtctt
gcagtggcaaattcattgggtgcagttgaaggcggagctcagcaggtgcattgcacagta
aatggattaggtgaaagggcaggaaatgcagctcttgaagaggtagtaatgtcattaatg
atgatttatggcatagataccaatataaataccgaaaaattgacagaaatatcaaattta
gtgtcaaaacttacaggtataaacacccagccaaataaggcagttgttggagaaaattca
tttgcccatgaaagtggaatacatgcccacggcgtgcttgcccatgctctcacttatgag
ccaatacctcctgaaattgttggtcaaaaaagaaaaatcatacttggaaaacatacagga
gctcatgctatccaatcaaagttaaaggagctcgggttggaagttggtaaaaatgtttca
gaggagcagtttaaggaaattgtaaatcgaataaaagacattggagataaaggtaagatg
attaccgatgccgatgtaatagcaattgttgaggatattacaaagagaaccataaaatca
aaaagaactgttaatttagaacaaatagcagtaatgacaggaaataagctaattcctacg
gcaagtgtagaattaataataaacaatgaaagatatattacttcaaaggttggagtagga
ccagtagatgctgcattaaaagccattcaatctgtgataggggagaaaataaagataaaa
gaataccatataaatgccatcacaggtggaactgatgccttagcagaagtaattgttaaa
ttagaaggctatggaaaagaaattacggcaaaagcagcaaatgaagacatagttagggca
tctgttgaggcaataattgatggaataaataaaataatggacatgtaa
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