KEGG   Microtus oregoni (creeping vole): 121435875
Entry
121435875         CDS       T08307                                 
Symbol
Akt3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01521  EGFR tyrosine kinase inhibitor resistance
morg01522  Endocrine resistance
morg01524  Platinum drug resistance
morg04010  MAPK signaling pathway
morg04012  ErbB signaling pathway
morg04014  Ras signaling pathway
morg04015  Rap1 signaling pathway
morg04022  cGMP-PKG signaling pathway
morg04024  cAMP signaling pathway
morg04062  Chemokine signaling pathway
morg04066  HIF-1 signaling pathway
morg04068  FoxO signaling pathway
morg04071  Sphingolipid signaling pathway
morg04072  Phospholipase D signaling pathway
morg04140  Autophagy - animal
morg04150  mTOR signaling pathway
morg04151  PI3K-Akt signaling pathway
morg04152  AMPK signaling pathway
morg04210  Apoptosis
morg04211  Longevity regulating pathway
morg04213  Longevity regulating pathway - multiple species
morg04218  Cellular senescence
morg04261  Adrenergic signaling in cardiomyocytes
morg04370  VEGF signaling pathway
morg04371  Apelin signaling pathway
morg04380  Osteoclast differentiation
morg04510  Focal adhesion
morg04550  Signaling pathways regulating pluripotency of stem cells
morg04611  Platelet activation
morg04613  Neutrophil extracellular trap formation
morg04620  Toll-like receptor signaling pathway
morg04625  C-type lectin receptor signaling pathway
morg04630  JAK-STAT signaling pathway
morg04660  T cell receptor signaling pathway
morg04662  B cell receptor signaling pathway
morg04664  Fc epsilon RI signaling pathway
morg04666  Fc gamma R-mediated phagocytosis
morg04668  TNF signaling pathway
morg04722  Neurotrophin signaling pathway
morg04725  Cholinergic synapse
morg04728  Dopaminergic synapse
morg04810  Regulation of actin cytoskeleton
morg04910  Insulin signaling pathway
morg04914  Progesterone-mediated oocyte maturation
morg04915  Estrogen signaling pathway
morg04917  Prolactin signaling pathway
morg04919  Thyroid hormone signaling pathway
morg04920  Adipocytokine signaling pathway
morg04922  Glucagon signaling pathway
morg04923  Regulation of lipolysis in adipocytes
morg04926  Relaxin signaling pathway
morg04929  GnRH secretion
morg04931  Insulin resistance
morg04932  Non-alcoholic fatty liver disease
morg04933  AGE-RAGE signaling pathway in diabetic complications
morg04935  Growth hormone synthesis, secretion and action
morg04936  Alcoholic liver disease
morg04973  Carbohydrate digestion and absorption
morg05010  Alzheimer disease
morg05017  Spinocerebellar ataxia
morg05132  Salmonella infection
morg05135  Yersinia infection
morg05142  Chagas disease
morg05145  Toxoplasmosis
morg05152  Tuberculosis
morg05160  Hepatitis C
morg05161  Hepatitis B
morg05162  Measles
morg05163  Human cytomegalovirus infection
morg05164  Influenza A
morg05165  Human papillomavirus infection
morg05166  Human T-cell leukemia virus 1 infection
morg05167  Kaposi sarcoma-associated herpesvirus infection
morg05168  Herpes simplex virus 1 infection
morg05169  Epstein-Barr virus infection
morg05170  Human immunodeficiency virus 1 infection
morg05200  Pathways in cancer
morg05205  Proteoglycans in cancer
morg05207  Chemical carcinogenesis - receptor activation
morg05208  Chemical carcinogenesis - reactive oxygen species
morg05210  Colorectal cancer
morg05211  Renal cell carcinoma
morg05212  Pancreatic cancer
morg05213  Endometrial cancer
morg05214  Glioma
morg05215  Prostate cancer
morg05218  Melanoma
morg05220  Chronic myeloid leukemia
morg05221  Acute myeloid leukemia
morg05222  Small cell lung cancer
morg05223  Non-small cell lung cancer
morg05224  Breast cancer
morg05225  Hepatocellular carcinoma
morg05226  Gastric cancer
morg05230  Central carbon metabolism in cancer
morg05231  Choline metabolism in cancer
morg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
morg05415  Diabetic cardiomyopathy
morg05417  Lipid and atherosclerosis
morg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:morg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    121435875 (Akt3)
   04015 Rap1 signaling pathway
    121435875 (Akt3)
   04630 JAK-STAT signaling pathway
    121435875 (Akt3)
   04668 TNF signaling pathway
    121435875 (Akt3)
   04066 HIF-1 signaling pathway
    121435875 (Akt3)
   04068 FoxO signaling pathway
    121435875 (Akt3)
   04072 Phospholipase D signaling pathway
    121435875 (Akt3)
   04071 Sphingolipid signaling pathway
    121435875 (Akt3)
   04024 cAMP signaling pathway
    121435875 (Akt3)
   04022 cGMP-PKG signaling pathway
    121435875 (Akt3)
   04151 PI3K-Akt signaling pathway
    121435875 (Akt3)
   04152 AMPK signaling pathway
    121435875 (Akt3)
   04150 mTOR signaling pathway
    121435875 (Akt3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    121435875 (Akt3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    121435875 (Akt3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121435875 (Akt3)
   04613 Neutrophil extracellular trap formation
    121435875 (Akt3)
   04620 Toll-like receptor signaling pathway
    121435875 (Akt3)
   04660 T cell receptor signaling pathway
    121435875 (Akt3)
   04662 B cell receptor signaling pathway
    121435875 (Akt3)
   04664 Fc epsilon RI signaling pathway
    121435875 (Akt3)
   04666 Fc gamma R-mediated phagocytosis
    121435875 (Akt3)
   04062 Chemokine signaling pathway
    121435875 (Akt3)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    121435875 (Akt3)
   04923 Regulation of lipolysis in adipocytes
    121435875 (Akt3)
   04929 GnRH secretion
    121435875 (Akt3)
   04915 Estrogen signaling pathway
    121435875 (Akt3)
   04917 Prolactin signaling pathway
    121435875 (Akt3)
   04926 Relaxin signaling pathway
    121435875 (Akt3)
   04935 Growth hormone synthesis, secretion and action
    121435875 (Akt3)
   04919 Thyroid hormone signaling pathway
    121435875 (Akt3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    121435875 (Akt3)
  09156 Nervous system
   04725 Cholinergic synapse
    121435875 (Akt3)
   04728 Dopaminergic synapse
    121435875 (Akt3)
   04722 Neurotrophin signaling pathway
    121435875 (Akt3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121435875 (Akt3)
  09149 Aging
   04211 Longevity regulating pathway
    121435875 (Akt3)
   04213 Longevity regulating pathway - multiple species
    121435875 (Akt3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121435875 (Akt3)
   05205 Proteoglycans in cancer
    121435875 (Akt3)
   05207 Chemical carcinogenesis - receptor activation
    121435875 (Akt3)
   05208 Chemical carcinogenesis - reactive oxygen species
    121435875 (Akt3)
   05230 Central carbon metabolism in cancer
    121435875 (Akt3)
   05231 Choline metabolism in cancer
    121435875 (Akt3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121435875 (Akt3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    121435875 (Akt3)
   05212 Pancreatic cancer
    121435875 (Akt3)
   05225 Hepatocellular carcinoma
    121435875 (Akt3)
   05226 Gastric cancer
    121435875 (Akt3)
   05214 Glioma
    121435875 (Akt3)
   05221 Acute myeloid leukemia
    121435875 (Akt3)
   05220 Chronic myeloid leukemia
    121435875 (Akt3)
   05218 Melanoma
    121435875 (Akt3)
   05211 Renal cell carcinoma
    121435875 (Akt3)
   05215 Prostate cancer
    121435875 (Akt3)
   05213 Endometrial cancer
    121435875 (Akt3)
   05224 Breast cancer
    121435875 (Akt3)
   05222 Small cell lung cancer
    121435875 (Akt3)
   05223 Non-small cell lung cancer
    121435875 (Akt3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121435875 (Akt3)
   05170 Human immunodeficiency virus 1 infection
    121435875 (Akt3)
   05161 Hepatitis B
    121435875 (Akt3)
   05160 Hepatitis C
    121435875 (Akt3)
   05164 Influenza A
    121435875 (Akt3)
   05162 Measles
    121435875 (Akt3)
   05163 Human cytomegalovirus infection
    121435875 (Akt3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121435875 (Akt3)
   05169 Epstein-Barr virus infection
    121435875 (Akt3)
   05165 Human papillomavirus infection
    121435875 (Akt3)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    121435875 (Akt3)
   05152 Tuberculosis
    121435875 (Akt3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    121435875 (Akt3)
   05142 Chagas disease
    121435875 (Akt3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121435875 (Akt3)
   05017 Spinocerebellar ataxia
    121435875 (Akt3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121435875 (Akt3)
   05418 Fluid shear stress and atherosclerosis
    121435875 (Akt3)
   05415 Diabetic cardiomyopathy
    121435875 (Akt3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    121435875 (Akt3)
   04932 Non-alcoholic fatty liver disease
    121435875 (Akt3)
   04931 Insulin resistance
    121435875 (Akt3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    121435875 (Akt3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121435875 (Akt3)
   01524 Platinum drug resistance
    121435875 (Akt3)
   01522 Endocrine resistance
    121435875 (Akt3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:morg01001]
    121435875 (Akt3)
Enzymes [BR:morg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     121435875 (Akt3)
Protein kinases [BR:morg01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   121435875 (Akt3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1 PH_11
Other DBs
NCBI-GeneID: 121435875
NCBI-ProteinID: XP_041491349
LinkDB
Position
Unknown
AA seq 479 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMECMDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aattggaggccaagatatttccttttgaagacagatggttcattcataggctataaagag
aaacctcaagatgtggacttaccttatcccctcaacaacttttctgtagcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaatacatttattatcagatgtcttcagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagagaagaatggacagaa
gctatccaagctgtagcagaccgactgcagagacaagaagaggagagaatgaattgtagt
ccaacttcacagattgataatataggagaagaagagatggatgcatctacaacccatcat
aaaagaaagacgatgaatgattttgactatttgaagctactaggtaaaggcacttttggg
aaggttattttagttcgagagaaggcaagtggaaaatactatgctatgaagattctgaag
aaagaagtcattattgcaaaggatgaagtggcacacactcttactgaaagcagagtacta
aagaacaccagacatccattcttaacatccttgaaatattccttccagacaaaagaccgt
ctgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgctttggac
tatctacattctggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccatataaaaattacagattttggactttgcaaagaaggaatcacagatgca
gccaccatgaagacattctgtggtaccccagaatatctggcaccagaggtattagaagat
aatgactatggccgagcagtagactggtggggcctgggtgttgtcatgtatgaaatgatg
tgtgggaggttgcctttctacaaccaggatcatgagaaactctttgaactaatactaatg
gaagacattaaatttccccgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggagggccagatgatgcaaaagaaattatg
aggcatagtttcttttctggagtaaactggcaagatgtgtacgacaaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagatacaagatattttgatgaagaatttaca
gctcaaactattacaataacaccacctgaaaaatatgatgaagatggcatggagtgcatg
gacaacgagcggcggccacatttccctcagttttcctactctgcaagtggacgagaataa

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