Microtus oregoni (creeping vole): 121444517
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Entry
121444517 CDS
T08307
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3-like
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00230
Purine metabolism
morg00670
One carbon pool by folate
morg01100
Metabolic pathways
morg01523
Antifolate resistance
Module
morg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121444517
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
121444517
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121444517
Enzymes [BR:
morg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
121444517
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
121444517
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
121444517
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_C
AIRS
AIRS_C
ATP-grasp_3
ATP-grasp_4
Motif
Other DBs
NCBI-GeneID:
121444517
NCBI-ProteinID:
XP_041502268
LinkDB
All DBs
Position
Unknown
AA seq
809 aa
AA seq
DB search
MTAKFLWVLEQQLAGYPETTAQILRVPQTAVRGSRDNNKGSASGLAAGKGVIVAKNKAEA
CKAVREIMQEKSFGAAGETVVVEEFLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDEG
PNTGGMGAYCPTPQVPKDLLLKIKDTILQRTVDGMQQEGVPYTGILYAGIMLTKDGPKVL
EFNCRFGDPECQVILPLLKSDLYEVIQSTLDGQLSASLPVWLENHTAITVVMASKGYPGA
YSKGVEITGFPEAQALGLQVFHAGTALKDGRVVTSGGRVLTVTAVQENLESARDEARKGL
AAIKFEGAVYRKDIGFRAVAFLQRPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRPGCT
VDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKHGTIGQDLVAMCVNDILAQ
GAEPLFFLDYFSCGKLDLTTTEAVIAGIAGACRQAGCALLGGETAEMPDMYPPGEYDLAG
FAVGAMERDQKLPQLERIVEGDVVVGVASSGLHSNGFSLVRKIVARSSLQHSSPAPDGCG
DQTLGDLLLTPTRIYSHSLLPVKALAHITGGGLLENIPRVLPRELGVDLGFPVLNTNPLG
SHCSKKLSPNSKRLKSCKASWVARLPGSQGVLAADFPRVRVKNLIETMQVNGSMVSNGFL
RSKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVVVISNKAGVAGLDKAEKAGIPTRVI
NHKLYKNRVEFDNAVDLVLEEFSVDVVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFK
GSNAHEQVLKAGVTVTGCTVHFVAVSMPF
NT seq
2430 nt
NT seq
+upstream
nt +downstream
nt
atgacagcaaagttcctgtgggtccttgagcagcagctggcagggtatcctgagacaaca
gcacagatcctgcgggtccctcagaccgccgtcagggggtcccgtgacaataacaaaggt
tctgccagtggccttgcagctgggaaaggggtgattgttgcaaagaacaaagcggaggcc
tgcaaagctgtacgggagatcatgcaggaaaagtcttttggagcagctggagaaacggtt
gttgtggaagagttcctggatggggaagaagtgtcttgtctgtgtttcactgatgggaag
acagtggccccaatgcctccagcacaggaccataagcgattgctggatggagatgagggc
cccaacacagggggaatgggagcctactgccctacacctcaggttcctaaggatttgtta
ctaaaaattaaagacactattcttcagagaacagtagacggcatgcagcaggagggtgtg
ccttacacaggaattctctatgctggtataatgctgaccaaagatggcccaaaagttttg
gagtttaattgccgttttggtgatccagaatgccaagtaatcctcccacttcttaaaagt
gacctttatgaagtgattcagtccaccttagatggccagctgagtgcgtctctgcctgtt
tggctagaaaaccacactgccataaccgttgtcatggcaagtaaagggtatcctggagcc
tacagcaagggtgtggagataacagggtttcctgaggcccaagctttaggactccaggta
ttccatgcgggcactgctcttaaagatggcagagtggtgaccagcgggggaagagtcctc
acagtaacggccgtccaggagaatcttgagtcagcccgtgacgaagccaggaaaggcctt
gctgccataaagtttgagggcgcagtttataggaaggacattggcttccgtgctgtagcc
ttcctccagcggcccaggggcctgacttacaaggaatctggggtagacattgcagctgga
aatatgctggttaagaaaattcagcctttagcaaaagccacctccagaccaggctgtact
gttgaccttggaggctttgctggtctttttgatttgaaagcagctggtttcaaagatcct
ctcctggcgtctggaacagatggtgttgggactaaactgaagattgcccagctgtgcaat
aagcatggcaccatcggtcaggatctggtcgcaatgtgtgtaaacgacatcctcgcacag
ggagctgagcccctcttcttcctcgattacttttcctgtggaaaactcgacctcactaca
actgaagctgttatcgctggaattgctggagcctgtagacaagctggctgtgctctccta
ggtggagagaccgcagagatgcccgacatgtaccctcctggcgagtatgacctcgctggg
tttgctgttggcgctatggagagggatcagaaactccctcagctagaaaggattgtcgaa
ggggatgttgtggttggggtagcctcatctggtcttcacagcaatggctttagccttgtg
aggaagattgtggcgaggtcttctctccagcactcctctccagcgcctgatggatgtggc
gaccagactttaggggacttgcttctaactccaaccaggatctacagccattcgctgttg
cctgtcaaagccttggctcacattactggaggtggattgctggaaaacatccccagagtc
cttcctcgggagctcggagtagatttaggtttcccagtgctgaacactaaccccttaggt
tcacactgcagtaagaagctttctccaaacagcaagcgtcttaagtcttgcaaagcctcc
tgggtcgcacgtctcccaggaagccagggggtcttagcggcagatttccctcgtgtcaga
gtcaagaatttgattgaaaccatgcaagtaaatgggtcaatggtgtcaaatggcttcctg
agaagtaagaaggccagagtggctgtcttaatatctggaacagggtccaacctccaggct
ctcatagacagcactcgggatccaaagagctcctcacacattgttgttgtcatctccaac
aaagctggggtcgctggcttagacaaagcagaaaaggctggcattcccaccagagtgatt
aatcataaattatataagaaccgtgttgaatttgacaatgctgttgacctcgtcctagaa
gagttctctgtagacgtggtctgtcttgccgggttcatgaggattctctctggccctttt
gtcaggaaatgggatggtaaaatgctcaacatccacccatccttgctcccttctttcaag
ggttcaaatgctcatgagcaagtcctgaaagctggagtcacagttaccgggtgcaccgta
cactttgtggccgtgagtatgcctttttag
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