KEGG   Microtus oregoni (creeping vole): 121450269
Entry
121450269         CDS       T08307                                 
Symbol
Nfkb1
Name
(RefSeq) nuclear factor NF-kappa-B p105 subunit isoform X1
  KO
K02580  nuclear factor NF-kappa-B p105 subunit
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01523  Antifolate resistance
morg04010  MAPK signaling pathway
morg04014  Ras signaling pathway
morg04024  cAMP signaling pathway
morg04062  Chemokine signaling pathway
morg04064  NF-kappa B signaling pathway
morg04066  HIF-1 signaling pathway
morg04071  Sphingolipid signaling pathway
morg04151  PI3K-Akt signaling pathway
morg04210  Apoptosis
morg04211  Longevity regulating pathway
morg04218  Cellular senescence
morg04380  Osteoclast differentiation
morg04613  Neutrophil extracellular trap formation
morg04620  Toll-like receptor signaling pathway
morg04621  NOD-like receptor signaling pathway
morg04622  RIG-I-like receptor signaling pathway
morg04623  Cytosolic DNA-sensing pathway
morg04625  C-type lectin receptor signaling pathway
morg04657  IL-17 signaling pathway
morg04658  Th1 and Th2 cell differentiation
morg04659  Th17 cell differentiation
morg04660  T cell receptor signaling pathway
morg04662  B cell receptor signaling pathway
morg04668  TNF signaling pathway
morg04722  Neurotrophin signaling pathway
morg04917  Prolactin signaling pathway
morg04920  Adipocytokine signaling pathway
morg04926  Relaxin signaling pathway
morg04931  Insulin resistance
morg04932  Non-alcoholic fatty liver disease
morg04933  AGE-RAGE signaling pathway in diabetic complications
morg04936  Alcoholic liver disease
morg05010  Alzheimer disease
morg05022  Pathways of neurodegeneration - multiple diseases
morg05030  Cocaine addiction
morg05132  Salmonella infection
morg05133  Pertussis
morg05134  Legionellosis
morg05135  Yersinia infection
morg05140  Leishmaniasis
morg05142  Chagas disease
morg05145  Toxoplasmosis
morg05146  Amoebiasis
morg05152  Tuberculosis
morg05160  Hepatitis C
morg05161  Hepatitis B
morg05162  Measles
morg05163  Human cytomegalovirus infection
morg05164  Influenza A
morg05165  Human papillomavirus infection
morg05166  Human T-cell leukemia virus 1 infection
morg05167  Kaposi sarcoma-associated herpesvirus infection
morg05168  Herpes simplex virus 1 infection
morg05169  Epstein-Barr virus infection
morg05170  Human immunodeficiency virus 1 infection
morg05171  Coronavirus disease - COVID-19
morg05200  Pathways in cancer
morg05202  Transcriptional misregulation in cancer
morg05203  Viral carcinogenesis
morg05206  MicroRNAs in cancer
morg05207  Chemical carcinogenesis - receptor activation
morg05208  Chemical carcinogenesis - reactive oxygen species
morg05212  Pancreatic cancer
morg05215  Prostate cancer
morg05220  Chronic myeloid leukemia
morg05221  Acute myeloid leukemia
morg05222  Small cell lung cancer
morg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
morg05321  Inflammatory bowel disease
morg05415  Diabetic cardiomyopathy
morg05417  Lipid and atherosclerosis
morg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:morg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121450269 (Nfkb1)
   04014 Ras signaling pathway
    121450269 (Nfkb1)
   04064 NF-kappa B signaling pathway
    121450269 (Nfkb1)
   04668 TNF signaling pathway
    121450269 (Nfkb1)
   04066 HIF-1 signaling pathway
    121450269 (Nfkb1)
   04071 Sphingolipid signaling pathway
    121450269 (Nfkb1)
   04024 cAMP signaling pathway
    121450269 (Nfkb1)
   04151 PI3K-Akt signaling pathway
    121450269 (Nfkb1)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    121450269 (Nfkb1)
   04218 Cellular senescence
    121450269 (Nfkb1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    121450269 (Nfkb1)
   04620 Toll-like receptor signaling pathway
    121450269 (Nfkb1)
   04621 NOD-like receptor signaling pathway
    121450269 (Nfkb1)
   04622 RIG-I-like receptor signaling pathway
    121450269 (Nfkb1)
   04623 Cytosolic DNA-sensing pathway
    121450269 (Nfkb1)
   04625 C-type lectin receptor signaling pathway
    121450269 (Nfkb1)
   04660 T cell receptor signaling pathway
    121450269 (Nfkb1)
   04658 Th1 and Th2 cell differentiation
    121450269 (Nfkb1)
   04659 Th17 cell differentiation
    121450269 (Nfkb1)
   04657 IL-17 signaling pathway
    121450269 (Nfkb1)
   04662 B cell receptor signaling pathway
    121450269 (Nfkb1)
   04062 Chemokine signaling pathway
    121450269 (Nfkb1)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    121450269 (Nfkb1)
   04917 Prolactin signaling pathway
    121450269 (Nfkb1)
   04926 Relaxin signaling pathway
    121450269 (Nfkb1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    121450269 (Nfkb1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121450269 (Nfkb1)
  09149 Aging
   04211 Longevity regulating pathway
    121450269 (Nfkb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121450269 (Nfkb1)
   05202 Transcriptional misregulation in cancer
    121450269 (Nfkb1)
   05206 MicroRNAs in cancer
    121450269 (Nfkb1)
   05207 Chemical carcinogenesis - receptor activation
    121450269 (Nfkb1)
   05208 Chemical carcinogenesis - reactive oxygen species
    121450269 (Nfkb1)
   05203 Viral carcinogenesis
    121450269 (Nfkb1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121450269 (Nfkb1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    121450269 (Nfkb1)
   05221 Acute myeloid leukemia
    121450269 (Nfkb1)
   05220 Chronic myeloid leukemia
    121450269 (Nfkb1)
   05215 Prostate cancer
    121450269 (Nfkb1)
   05222 Small cell lung cancer
    121450269 (Nfkb1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121450269 (Nfkb1)
   05170 Human immunodeficiency virus 1 infection
    121450269 (Nfkb1)
   05161 Hepatitis B
    121450269 (Nfkb1)
   05160 Hepatitis C
    121450269 (Nfkb1)
   05171 Coronavirus disease - COVID-19
    121450269 (Nfkb1)
   05164 Influenza A
    121450269 (Nfkb1)
   05162 Measles
    121450269 (Nfkb1)
   05168 Herpes simplex virus 1 infection
    121450269 (Nfkb1)
   05163 Human cytomegalovirus infection
    121450269 (Nfkb1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121450269 (Nfkb1)
   05169 Epstein-Barr virus infection
    121450269 (Nfkb1)
   05165 Human papillomavirus infection
    121450269 (Nfkb1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    121450269 (Nfkb1)
   05135 Yersinia infection
    121450269 (Nfkb1)
   05133 Pertussis
    121450269 (Nfkb1)
   05134 Legionellosis
    121450269 (Nfkb1)
   05152 Tuberculosis
    121450269 (Nfkb1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    121450269 (Nfkb1)
   05145 Toxoplasmosis
    121450269 (Nfkb1)
   05140 Leishmaniasis
    121450269 (Nfkb1)
   05142 Chagas disease
    121450269 (Nfkb1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    121450269 (Nfkb1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121450269 (Nfkb1)
   05022 Pathways of neurodegeneration - multiple diseases
    121450269 (Nfkb1)
  09165 Substance dependence
   05030 Cocaine addiction
    121450269 (Nfkb1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121450269 (Nfkb1)
   05418 Fluid shear stress and atherosclerosis
    121450269 (Nfkb1)
   05415 Diabetic cardiomyopathy
    121450269 (Nfkb1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    121450269 (Nfkb1)
   04932 Non-alcoholic fatty liver disease
    121450269 (Nfkb1)
   04931 Insulin resistance
    121450269 (Nfkb1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    121450269 (Nfkb1)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    121450269 (Nfkb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:morg03000]
    121450269 (Nfkb1)
Transcription factors [BR:morg03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    121450269 (Nfkb1)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer Ank_2 Ank Ank_4 Ank_3 Ank_5 Death
Other DBs
NCBI-GeneID: 121450269
NCBI-ProteinID: XP_041511018
LinkDB
Position
Unknown
AA seq 990 aa
MADDDPYGTGQMFHLNSALSHPIFNTELYAPEMPLSTDGPYLQILEQPKQRGFRFRYVCE
GPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGI
CTVVAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEG
GGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDS
KAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDFSP
TDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRK
RQKLMPNFSDSFGGGGSGAGAGGGGMFGSGGGGGSTGNPGPGYGFPHYGFPTYSGITFHP
GVTKSNAGITHGTTNTDLKNNPKDCDESGDREIGNLSEKEPAAQDKESGMSSVKTDAVAL
ASTVEDKEWGAGFQVASLRCSMYLCIVYVYKTDNLFLEKALQLAKRHANALFDYAVTGDV
KMLLAVQRHLTVVQDENGDSVLHLAIIHLHAQLVKDLLEVTSGLISNDIINMRNDLYQTP
LHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLHMAAREGHDKILSVLLKNKKAAPLID
HPNGEGLNAIHIAVMSNSLPCLLLLVAAGAEVNAQEQKSGRTALHLAMEYDNISLAGCLL
LEGDADVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDESWEKDGE
DEGVVPGITPLDVATNWQVFDILNGKPYERVFTSDDILPQGDMKQLPEDTRLQLHKLLEL
PDPDKNWATLAQKLGLGILNSAFRLSPAPSKTFMDNYEVSGGTIKELMEALRQMGYTEAI
EVIQSAFCTPETTASSPVTTARAPEPPLSSSSTRQHLDELRDNDSICDSGVETSFHKLSF
TESLPGDSSVLSLNKMPHNYGQEGPIEGKI
NT seq 2973 nt   +upstreamnt  +downstreamnt
atggcggacgatgacccatatggaaccgggcagatgtttcatttgaattctgcgttgtct
catccaatatttaacacagaattatatgcaccagaaatgcccctgtcaacggatggccca
taccttcaaatattagagcaaccaaaacagaggggatttcgattccgctatgtgtgtgaa
ggcccatcacatggcgggctccctggtgcctctagtgagaagaacaagaaatcctaccct
caggtcaaaatttgcaactatgtgggacctgcaaaggttattgttcagttggtcacaaat
gggaaaaatatccacctgcatgcccacagcctggtgggcaaacactgtgaagacgggatc
tgcactgtggtagccggccccaaggacatggtggttggctttgcaaacctgggcatactt
catgtaaccaagaaaaaggtgtttgaaaccctagaagcacggatgacagaggcgtgtata
aggggctataatcctggactcttggtgcattctgaccttgcctatctacaagcagaaggt
ggaggagaccggcagctcacagacagggagaaagaaatcatccgccaggcggctctgcag
caaaccaaggagatggacctgagtgtggtgcgcctcatgttcacagccttccttcccgac
agcaccggcagcttcacccggaggctggagcccgtggtgtcggacgccatctacgacagc
aaggcccccaatgcatctaacctgaaaatcgtaaggatggacagaacagcagggtgtgta
acaggaggagaagaaatctaccttctctgtgacaaggttcagaaagatgacatccagatt
cggttttatgaagaggaagaaaatggtggaatttgggaaggatttggagacttttccccc
acggatgttcataggcagtttgccattgtcttcaaaactccaaagtataaggatgtcaac
attacaaaaccagcttctgtatttgttcagcttcggaggaaatcggacttggaaacgagt
gaaccaaaacccttcctctactaccctgaaatcaaagacaaagaggaagtgcagaggaag
cgccagaagctcatgcccaacttctcggacagtttcggcggtggtggcagtggagccgga
gcgggcggtggtggcatgttcggcagtggtggtggcggagggagtaccggaaatcccggc
ccagggtatggcttcccgcactatggatttcctacttacagtgggattacattccatcct
ggagtcactaaatccaacgctgggatcacccatggaactacaaatacagatttgaaaaat
aaccctaaagactgtgacgagagtggtgaccgagagattgggaatctctctgagaaggaa
ccagccgcacaggataaggagtctggcatgtccagcgtgaagaccgatgcagtcgcactg
gcgtccaccgtggaagacaaggaatggggtgccgggtttcaggttgcctctttgagatgc
tccatgtatctatgtattgtgtatgtctacaaaaccgataacctctttcttgagaaggct
ctgcagctggccaagcggcatgccaatgcccttttcgactacgcggtgacgggagacgtg
aagatgttgctggctgtgcagcgccatctcaccgtggtgcaggatgagaacggagacagt
gtcttacacttagccatcatccaccttcatgctcagcttgtgaaggatctactggaagtc
acatccggtttgatctccaatgacatcatcaacatgagaaatgatctgtatcagacacct
ctgcacttggccgtaatcaccaagcaggaagatgtggtggaggacttgctgagggttggg
gctgacctgagccttctggaccgctggggcaactccgttctgcacatggctgccagagaa
gggcacgataagatcctcagtgtccttctgaagaacaagaaagcagcgccccttattgac
caccccaacggggaaggtctcaatgccatccacatagctgtgatgagcaatagcctgcca
tgtctgctgctgcttgtggctgcgggggcagaagtcaatgctcaggaacagaagtctggg
cgcacggcactgcacctggccatggaatacgacaacatctcgctggctggctgcctgctt
ctggagggcgatgccgatgtggacagcaccacctacgatgggactacacctctacacata
gcagccggaagagggtccaccagactggcagctcttctcaaagctgcaggagcagacccc
ctggtggagaactttgagcctctctatgacctggacgagtcctgggagaaggatggagaa
gacgagggagtggtaccaggcatcacacccctagacgtggctaccaactggcaggtgttt
gacatactaaatgggaagccatatgagcgtgtgttcacatcagatgatattctaccacaa
ggagacatgaaacagcttcccgaagacaccagactacagctccacaagctgctggagctc
cctgatccagacaaaaactgggccactctggcacagaagttaggtctggggatacttaac
agtgccttccggctgagccctgctccttctaaaaccttcatggacaactatgaggtctct
gggggcaccatcaaagagctgatggaggccctgcggcagatgggctacacagaggccatt
gaagtgatccagtcagccttctgcaccccggaaaccacagcctccagccccgtgaccact
gctcgggcccccgaaccgcctctctcatcttcctctacaaggcagcacctagatgagctc
cgggacaacgacagtatctgtgacagtggtgtggagacgtccttccacaaactcagcttt
acagagtctttacctggagacagctcagtgctatctctgaacaaaatgccccacaattac
gggcaggaaggacctatagaaggcaaaatttag

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