Microtus oregoni (creeping vole): 121451603
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Entry
121451603 CDS
T08307
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg04217
Necroptosis
morg04380
Osteoclast differentiation
morg04620
Toll-like receptor signaling pathway
morg04621
NOD-like receptor signaling pathway
morg04630
JAK-STAT signaling pathway
morg04658
Th1 and Th2 cell differentiation
morg04659
Th17 cell differentiation
morg05145
Toxoplasmosis
morg05160
Hepatitis C
morg05161
Hepatitis B
morg05162
Measles
morg05164
Influenza A
morg05165
Human papillomavirus infection
morg05167
Kaposi sarcoma-associated herpesvirus infection
morg05168
Herpes simplex virus 1 infection
morg05169
Epstein-Barr virus infection
morg05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
121451603 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
121451603 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
121451603 (Tyk2)
04621 NOD-like receptor signaling pathway
121451603 (Tyk2)
04658 Th1 and Th2 cell differentiation
121451603 (Tyk2)
04659 Th17 cell differentiation
121451603 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
121451603 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
121451603 (Tyk2)
05160 Hepatitis C
121451603 (Tyk2)
05171 Coronavirus disease - COVID-19
121451603 (Tyk2)
05164 Influenza A
121451603 (Tyk2)
05162 Measles
121451603 (Tyk2)
05168 Herpes simplex virus 1 infection
121451603 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
121451603 (Tyk2)
05169 Epstein-Barr virus infection
121451603 (Tyk2)
05165 Human papillomavirus infection
121451603 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
121451603 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
morg01001
]
121451603 (Tyk2)
Enzymes [BR:
morg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
121451603 (Tyk2)
Protein kinases [BR:
morg01001
]
Non-receptor tyrosine kinases
JAK family [OT]
121451603 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
121451603
NCBI-ProteinID:
XP_041513216
LinkDB
All DBs
Position
Unknown
AA seq
1184 aa
AA seq
DB search
MVATMPLCGRRTMSEDSRADGTEAQPLVPTESLMVLLHWTGPEGGEPWVTFSQTSLTAED
ICIQIAHKVGITPPCLNLFALYDAQAKVWLPPNHVLDTSRDVSLRLYFRMRFYFRNWHGM
SPQEPAVYRCGSLGSEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSEEEIHHFKNE
SLGMAFLHLCHLALCRGVPLEEMAREISFKNCIPRSFRQHIRQHNALTRLRLRRVFRRFL
RAFRPGHLSQQVVMVKYLATLERLAPRFGSEHIPVCHLEVLDQPERDPCYIQNSGQTTGD
PGPELATRLPTHEVLVTGTRGIQWRPLQIQESARGNSRGNPQGNRSGKKVKAPEVAEQLA
KSPGEPSWTYFCDFQDISHVVLKDCHVRIHRQDNKCMLLCLRSRAEALSFVALVDGYFRL
TADSSHYLCHEVAPPRLLTSIQNGIHGPLMDPFVQAKLWPEDGLYLIQWSTSHLHRLILT
VAHRDSAPNSGPKGLRLRKFPITQQPGAFVLDGWGRSFDSVGDLRVALQGCSLRAGDDCF
PLHHCCLPRPGEISNLLVMRGSSAHTRPLNLSQLSFHRVHQDEITQLSHLGQGTRTNVYE
GLLRVGGPDEGKTDSGCPPEPGGGIGQQLRVVLKVLDPSHHDIALAFYETASLMSQVAHM
HLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRHRGRVPMTWKMIVAQQLASALSYLEDK
NLVHGNVCGRNVLLARLGLEEGTSPFIKLSDPGVGQGALSREERVERIPWTAPECLSGEI
SSLGTATDMWGFGATLLEICFDGDAPLQGRCSSEKERFYTKQHQLPEPSCPELATLTRQC
LTYEPAQRPSFRTILRDLTRLQPQNLVGISAVNSDSAASDPTVFHKRYLKKIRDLGEGHF
GKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCED
QGVPGHGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHGQHYIHRD
LAARNVLLDNERLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASD
VWSFGVTLYELLTYCDSRQSPPTKFMELIGVTQGQMTVLRLTELLERGERLPRPDRCPCE
IYLLMKNCWEAEASFRPTFQNLVPILKTAQEKYQGQVPSVFSVC
NT seq
3555 nt
NT seq
+upstream
nt +downstream
nt
atggtggcaactatgcctctgtgtgggcggagaaccatgtcagaagacagcagggcagat
ggcaccgaagctcagcccctggtacccacagaaagcttgatggtgctgctgcactggact
gggcccgagggcggggagccttgggtcaccttcagccagacgtctctgactgccgaggac
atctgcatccagattgcacacaaagtcggcatcactccaccctgcctgaatctctttgcc
ctctatgatgcacaggccaaggtctggctgcccccaaaccacgtcctagacacatcccga
gatgtgagcctaaggctatatttccgaatgaggttttacttccggaactggcacggcatg
agtccccaagagccagctgtgtaccgatgtggttccctggggtcagagcagggtgtgcag
ctcttggactctgcctcatttgaatacctctttgagcagggaaaacatgagttcatgaat
gatgtggtgtctctgcgggacctgtctagtgaggaagagatccatcactttaagaatgag
agcttgggcatggcctttctgcacctctgccaccttgctctctgccgcggtgtccccctg
gaggagatggccagagagatcagctttaagaactgcatccctcgttccttccgccagcac
atccgtcagcacaatgcgctcacgcgcctgcgtctccgcagagtcttccggcgattcctg
cgggcctttcggcctggccacctctcccagcaggttgtgatggttaagtacttggccacc
ctggagcggctggcccctcgatttggctcagagcacataccggtgtgtcatctggaggtg
ctggaccagcctgagagggacccctgctacatccagaacagtgggcagactactggagac
ccaggcccagagctggccaccaggcttcccacccatgaggtactggtgacaggcaccaga
ggtatccagtggcgtccactacagatccaggaatctgcaagaggtaacagcagagggaat
ccccaaggcaaccgatctggaaagaaagtcaaggcccctgaggttgccgagcagctggcc
aagagtcctggggagccatcctggacctacttctgcgacttccaggacatctcccatgta
gtgctaaaggactgtcacgtgcgcatccaccgtcaggacaacaagtgcatgttgctgtgc
ctccgttcccgggctgaagccctgtcctttgtggccctggtggatggctatttccgcttg
accgccgactccagccactacctgtgccatgaggtggcacccccgcggctgttgaccagc
atccagaatggcatccatgggcccctgatggatccatttgtgcaagccaagctgtggccg
gaggatggcctctacctgatccagtggagcaccagccacctccaccgtctgatcctcact
gtggcccatcgagactcagctcccaacagcggccccaagggtctgcgcctccgaaagttc
cccatcacccagcaacctggagcctttgtgctagatggctggggtcgctccttcgacagc
gtgggggaccttcgggtcgccttgcagggctgctcgctgcgggctggtgacgactgcttc
cctttgcaccactgctgcctgccccggccaggagaaatctccaacctcttggtcatgcgg
gggtccagtgcccacacccggcctctcaacctcagccagctcagcttccacagagttcac
caggatgaaatcacgcagctgtcccacttgggtcaaggcacgaggaccaatgtttacgag
ggccttctaagagtgggaggccctgacgaaggcaaaactgacagtggatgccctcctgag
cctggcgggggcattggtcagcagctccgagtggtgcttaaagtcctggaccccagtcac
catgacatcgccttggccttctatgaaacagccagcctcatgagccaggtggcacacatg
cacctggctttcctgcatggtgtctgcgtgcgtggctcagagaatatcattgtgacagag
ttcgtagaacacggtcccctggatgtgtggttacggcgacacaggggccgagtgcctatg
acctggaagatgattgtggctcagcagctggccagtgccctcagctacctggaggacaag
aatctggttcacgggaatgtatgtggccggaacgtcctgctggcgcggctggggttagag
gagggtaccagccccttcatcaagttaagtgatcctggcgtaggccaaggtgccctctcc
agagaggagcgggtggaacgcatcccctggacagctcctgagtgcctgtctggagagatc
agtagcttgggtactgccacggacatgtggggttttggtgccacccttcttgagatctgc
tttgatggggatgcacccctgcagggtcgttgctcctccgagaaagaacgattctacaca
aagcagcaccagctgcctgagccctcatgcccggagctggccacactcacccgccagtgc
ctgacctacgaaccagcacagcggccatcattccgcaccattttgcgggacctcaccagg
ctgcagccacagaatctagtgggtatctcggctgtgaactcagactcagcagcatcagac
cccacggttttccacaaacgttatttgaaaaagatccgggatttgggcgagggtcacttt
ggcaaggtcagcctgtactgctatgatccaaccaatgatggcactggcgagatggtggct
gtgaaagcccttaaggagggctgtggtccccagctccgctcaggctggcagcgggagatc
gaaatcctgcggaccctgtaccatgaacatattgtcaagtacaaaggctgctgtgaggac
caaggtgtgccaggccatggagagaagtctgtacagctggtcatggaatacgtccccctg
ggcagccttcgggactacctgccacggcacagcgttgggctggctcagcttctgttgttt
gcccagcagatctgcgagggcatggcctacctgcacgggcaacactacattcaccgagac
ctagctgcgcgcaatgtgcttctggacaatgagaggctggtcaagattggagactttggc
ttagccaaggcagtgcctgaaggccatgagtactaccgcgttcgcgaagacggggacagc
ccagtgttctggtatgccccggaatgtctgaaggagtgcaaattttactatgcgtcagat
gtctggtctttcggggtgaccctgtacgagctgttgacctactgtgactctaggcagagc
ccccccacgaaattcatggagctcatcggcgtcacccagggccagatgaccgtgctgagg
ctcacggagctgctggagcgaggagagcggctgcctcggcctgacaggtgtccgtgtgag
atctatctcctcatgaagaactgctgggaggcagaggcctccttccgacccacgttccag
aatcttgtgcctatcctcaagacagcccaggagaagtaccaaggccaggtgccttcagtg
ttcagtgtgtgctga
DBGET
integrated database retrieval system
