Microtus oregoni (creeping vole): 121452307
Help
Entry
121452307 CDS
T08307
Symbol
Sos2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg01521
EGFR tyrosine kinase inhibitor resistance
morg01522
Endocrine resistance
morg04010
MAPK signaling pathway
morg04012
ErbB signaling pathway
morg04014
Ras signaling pathway
morg04062
Chemokine signaling pathway
morg04068
FoxO signaling pathway
morg04072
Phospholipase D signaling pathway
morg04150
mTOR signaling pathway
morg04151
PI3K-Akt signaling pathway
morg04510
Focal adhesion
morg04540
Gap junction
morg04630
JAK-STAT signaling pathway
morg04650
Natural killer cell mediated cytotoxicity
morg04660
T cell receptor signaling pathway
morg04662
B cell receptor signaling pathway
morg04664
Fc epsilon RI signaling pathway
morg04714
Thermogenesis
morg04722
Neurotrophin signaling pathway
morg04810
Regulation of actin cytoskeleton
morg04910
Insulin signaling pathway
morg04912
GnRH signaling pathway
morg04915
Estrogen signaling pathway
morg04917
Prolactin signaling pathway
morg04926
Relaxin signaling pathway
morg04935
Growth hormone synthesis, secretion and action
morg05034
Alcoholism
morg05160
Hepatitis C
morg05161
Hepatitis B
morg05163
Human cytomegalovirus infection
morg05165
Human papillomavirus infection
morg05200
Pathways in cancer
morg05205
Proteoglycans in cancer
morg05206
MicroRNAs in cancer
morg05207
Chemical carcinogenesis - receptor activation
morg05208
Chemical carcinogenesis - reactive oxygen species
morg05210
Colorectal cancer
morg05211
Renal cell carcinoma
morg05213
Endometrial cancer
morg05214
Glioma
morg05215
Prostate cancer
morg05220
Chronic myeloid leukemia
morg05221
Acute myeloid leukemia
morg05223
Non-small cell lung cancer
morg05224
Breast cancer
morg05225
Hepatocellular carcinoma
morg05226
Gastric cancer
morg05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
121452307 (Sos2)
04630 JAK-STAT signaling pathway
121452307 (Sos2)
04068 FoxO signaling pathway
121452307 (Sos2)
04072 Phospholipase D signaling pathway
121452307 (Sos2)
04151 PI3K-Akt signaling pathway
121452307 (Sos2)
04150 mTOR signaling pathway
121452307 (Sos2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
121452307 (Sos2)
04660 T cell receptor signaling pathway
121452307 (Sos2)
04662 B cell receptor signaling pathway
121452307 (Sos2)
04664 Fc epsilon RI signaling pathway
121452307 (Sos2)
04062 Chemokine signaling pathway
121452307 (Sos2)
09152 Endocrine system
04915 Estrogen signaling pathway
121452307 (Sos2)
04917 Prolactin signaling pathway
121452307 (Sos2)
04926 Relaxin signaling pathway
121452307 (Sos2)
04935 Growth hormone synthesis, secretion and action
121452307 (Sos2)
09156 Nervous system
04722 Neurotrophin signaling pathway
121452307 (Sos2)
09159 Environmental adaptation
04714 Thermogenesis
121452307 (Sos2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121452307 (Sos2)
05206 MicroRNAs in cancer
121452307 (Sos2)
05205 Proteoglycans in cancer
121452307 (Sos2)
05207 Chemical carcinogenesis - receptor activation
121452307 (Sos2)
05208 Chemical carcinogenesis - reactive oxygen species
121452307 (Sos2)
05231 Choline metabolism in cancer
121452307 (Sos2)
09162 Cancer: specific types
05210 Colorectal cancer
121452307 (Sos2)
05225 Hepatocellular carcinoma
121452307 (Sos2)
05226 Gastric cancer
121452307 (Sos2)
05214 Glioma
121452307 (Sos2)
05221 Acute myeloid leukemia
121452307 (Sos2)
05220 Chronic myeloid leukemia
121452307 (Sos2)
05211 Renal cell carcinoma
121452307 (Sos2)
05215 Prostate cancer
121452307 (Sos2)
05213 Endometrial cancer
121452307 (Sos2)
05224 Breast cancer
121452307 (Sos2)
05223 Non-small cell lung cancer
121452307 (Sos2)
09172 Infectious disease: viral
05161 Hepatitis B
121452307 (Sos2)
05160 Hepatitis C
121452307 (Sos2)
05163 Human cytomegalovirus infection
121452307 (Sos2)
05165 Human papillomavirus infection
121452307 (Sos2)
09165 Substance dependence
05034 Alcoholism
121452307 (Sos2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121452307 (Sos2)
01522 Endocrine resistance
121452307 (Sos2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
121452307
NCBI-ProteinID:
XP_041514303
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
DIGLISLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFRPSE
IEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQD
ILSPEFNDLFSKLMTRPAVVLHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLK
ACSEEQEDRECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKK
MNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHCQTRLP
GCSNAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSVIFAAKSAEEKNNWMAAL
ISLHYRSTLDRMLDSVLLKEENEQPLRLPSPDAYRFVVKDSEENIVFEDNLQSRSGIPII
KGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKL
ALEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSV
RGKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHP
IEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVE
AENFEERVAVLSRVIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRIL
DDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKR
RKVAEITGEIQQYQNQPYCLRTEPEIRRFFENLNPMGILSEKEFTDYLFNKSQEIEPRNC
KQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPYKISFSRIAETELEST
VSAPTSPNTPSTPPVSASSDHSVFLDVDLNSSCGSNTIFAPVLLPQSKTFFSSCGSIHKL
SEEPLIPPPLPPRKKVDHDASNSKGTMKSDDDPPAIPPRQPPPPKVKPRVPVPVAAFDGP
VHSPPPPPPREPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHPHRDPDWLRDASSSPSSP
STPPSTPSPRVPRRSHLLSSSHGALVHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPL
YRLPLLENAETPQ
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgagttcttcagcgaagaaaacagcccgaaatggcgg
ggactgctggtcccggccctgcggaaggttcaggaacaagtacatcccaccctctcagct
aatgaagagtccctttattatattgaagaactgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtagaggaacgagtccaaaagacgtttcctcac
cctattgataaatgggcaattgctgatgcccagtctgccatcgagaaacgtaaaagaaga
aatcctcttttactacctgtggacaaaatccatccttccttgaaggaagttttggggtac
aaagtggactaccatgtgtccctctacattgtggctgtattggagtatatctcagctgat
attttgaaattggctggtaattatgtttttaatatccggcattatgaaatatctcagcaa
gacattaaagtatcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgat
gatataggtttgatttctctctgtgaagacgaacctagttcttctggtgagctaaactac
tatgatcttgtcagaactgaaattgcagaagagaggcagtacctccgggagctgaatatg
atcatcaaagtgttccgggaagcctttctttctgaccggaagctgttcaggccttctgaa
attgaaaagattttcagtaacatttcagatatccatgaattgactgtgaaacttttaggt
ttgattgaagacacagtagaaatgacagatgaaagtagtccccatccgttagctggcagc
tgttttgaagatttagcagaggagcaagcatttgatccctatgaaacgctatcacaggac
attctctcgccagagtttaatgacctcttcagtaagttgatgaccagacctgcagttgtt
ctacattttcagtccattgctgacggctttaaggaggctgttcgttacgtcctgccacgt
cttatgctggtgccggtgtatcattgttggcattacttcgagttgttaaagcagttgaaa
gcatgtagtgaagaacaggaagacagagagtgtttgaatcaggctatcactgctctcatg
aatctccagggcagcatggacagaatttataagcagcattcacctagacgccgaccaggg
gaccctgtttgcctattttacaatcgtcaattaagaagcaagcatctagctattaaaaaa
atgaatgaaattcagaaaaacatagatgggtgggaaggcaaagatattggacagtgctgt
aatgaattcataatggaggggccattgaccagaattggtgctaaacacgagagacatatt
ttcctctttgacggcttgatgatcagctgtaaacctaatcattgccagacccgacttccc
ggctgcagtaatgcagagtacaggttaaaagagaagtttgtcatgaggaaaattcaaatc
tgtgataaggaagacacttgtgaatgcaaacatgcttttgaattagtttccaaagatgaa
aacagtgtaatatttgctgctaagtcagcagaagagaagaataattggatggcagccctc
atctccctccactaccgaagtactctggacagaatgctggactccgtgctgctgaaggag
gagaacgagcagccgctcaggctgccaagtccagacgcgtatcgctttgtggtaaaggac
tctgaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattatt
aaaggaggaactgtggtgaaattaattgaaaggttaacatatcatatgtatgcagatccc
aatttcgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgcta
agcttgctgatagaacggtttgaaattccggaaccagaacctactgaggcagacaaattg
gcactagagaaaggcgagcaacccatcagtgcagatctgaaaagatttcgcaaggaatac
gtccaacctgtgcaactcaggatcttaaatgtctttcgccactgggttgaacatcatttt
tatgactttgaaagagacctggaattgcttgaaagactagaatccttcatttcaagtgta
agagggaaggctatgaagaaatgggtagagtccattgctaaaatcatcaagaggaaaaag
caagctcaggcaaatggaataagccataatattacctttgaaagtccacctccaccaatc
gaatggcatataagtagaccaggccagtttgagacatttgaccttatgacacttcatcca
atagaaattgcacggcagttgacgcttttggagtctgatctgtacaggaaagtccaaccg
tctgaacttgtagggagtgtctggaccaaagaagataaagaaataaactctccaaattta
ttaaaaatgattcgccatacaacaaacctcactctctggtttgaaaaatgcattgtggaa
gcggaaaactttgaggagcgggtggcggtgctcagcagagtaatagaaatcctgcaggtc
ttccaagatttgaataatttcaatggcgtgttggaaatagtcagtgcggtcaactcggta
tcagtatacaggctagaccacacgtttgaggcattgcaagaaaggaaaaggagaattcta
gatgatgctgtggaattgagtcaggaccacttcaaaaaatacttagtaaaactgaagtca
atcaatccaccatgcgtgcctttttttggaatatatttaacaaatattctgaagactgaa
gaagggaacaatgattttctaaagaagaaagggaaagatctaatcaatttcagtaagagg
aggaaagtggctgagattaccggagaaattcagcagtatcagaaccagccttactgctta
cggacggaaccagaaataaggagattctttgaaaaccttaaccccatgggaattttatct
gaaaaagagtttacagattatttgttcaacaaatcacaagaaattgaaccccgaaactgc
aaacaaccgcctcgatttcctaggaaatcaaccttttccttaaaatctcctggaatcagg
cctaacacaggccggcatggctctacctcaggcacattacgaggtcacccaacgcctttg
gaaagagaaccatacaagataagctttagtaggatcgctgagaccgagctcgaatcaaca
gtgtcagcacccacctctccaaacacaccatccacaccacccgtgtctgcttcttcagac
cacagcgtgtttctagacgttgatctcaatagttcctgtggcagcaataccatctttgca
ccagtcctcttgccgcaatcgaagaccttcttcagctcatgtggaagcatacacaagctg
agtgaagagccactgattcctcctccccttcctcctcggaaaaaagttgatcatgatgct
tcaaattctaagggaactatgaaatctgatgatgacccccctgctattccaccaagacag
ccgccccctccaaaggtaaagccgagagttcctgttcccgtggctgcttttgatgggcct
gtgcacagtccacctccaccccctccgagagagcctcttcctgatacccccccaccagtt
cctcttcggccgccagaacactttataaactgcccgtttaaccttcagccacctccgctg
ggacatccccacagagacccagactggctcagagacgctagttcgagtccgagttcgcca
agcactcctcccagcacgccctcgccacgagtgccacgcagaagccatttgctcagttcc
agccacggcgctcttgtgcatcctccagctcctcctgttccaccacggcagaactcaagc
cctcacctaccaaaactgccaccaaagacttacaaacgggagctttcacacccaccgttg
tacagactgcctttgctcgaaaatgcagaaactcctcaatga
DBGET
integrated database retrieval system
