Microtus oregoni (creeping vole): 121453621
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Entry
121453621 CDS
T08307
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg01521
EGFR tyrosine kinase inhibitor resistance
morg01522
Endocrine resistance
morg04010
MAPK signaling pathway
morg04014
Ras signaling pathway
morg04015
Rap1 signaling pathway
morg04066
HIF-1 signaling pathway
morg04068
FoxO signaling pathway
morg04081
Hormone signaling
morg04114
Oocyte meiosis
morg04140
Autophagy - animal
morg04144
Endocytosis
morg04150
mTOR signaling pathway
morg04151
PI3K-Akt signaling pathway
morg04152
AMPK signaling pathway
morg04211
Longevity regulating pathway
morg04213
Longevity regulating pathway - multiple species
morg04510
Focal adhesion
morg04520
Adherens junction
morg04550
Signaling pathways regulating pluripotency of stem cells
morg04730
Long-term depression
morg04913
Ovarian steroidogenesis
morg04914
Progesterone-mediated oocyte maturation
morg05200
Pathways in cancer
morg05202
Transcriptional misregulation in cancer
morg05205
Proteoglycans in cancer
morg05214
Glioma
morg05215
Prostate cancer
morg05218
Melanoma
morg05224
Breast cancer
morg05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121453621 (Igf1r)
04014 Ras signaling pathway
121453621 (Igf1r)
04015 Rap1 signaling pathway
121453621 (Igf1r)
04066 HIF-1 signaling pathway
121453621 (Igf1r)
04068 FoxO signaling pathway
121453621 (Igf1r)
04151 PI3K-Akt signaling pathway
121453621 (Igf1r)
04152 AMPK signaling pathway
121453621 (Igf1r)
04150 mTOR signaling pathway
121453621 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
121453621 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
121453621 (Igf1r)
04140 Autophagy - animal
121453621 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
121453621 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
121453621 (Igf1r)
04520 Adherens junction
121453621 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
121453621 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
121453621 (Igf1r)
04914 Progesterone-mediated oocyte maturation
121453621 (Igf1r)
09156 Nervous system
04730 Long-term depression
121453621 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
121453621 (Igf1r)
04213 Longevity regulating pathway - multiple species
121453621 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121453621 (Igf1r)
05202 Transcriptional misregulation in cancer
121453621 (Igf1r)
05205 Proteoglycans in cancer
121453621 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
121453621 (Igf1r)
05214 Glioma
121453621 (Igf1r)
05218 Melanoma
121453621 (Igf1r)
05215 Prostate cancer
121453621 (Igf1r)
05224 Breast cancer
121453621 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
121453621 (Igf1r)
01522 Endocrine resistance
121453621 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
morg01001
]
121453621 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
morg04090
]
121453621 (Igf1r)
Enzymes [BR:
morg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
121453621 (Igf1r)
Protein kinases [BR:
morg01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
121453621 (Igf1r)
CD molecules [BR:
morg04090
]
Proteins
121453621 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
B2
Motif
Other DBs
NCBI-GeneID:
121453621
NCBI-ProteinID:
XP_041516448
LinkDB
All DBs
Position
Unknown
AA seq
1373 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPMCEKTTINNEYNYRCWTTNHCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPLGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHD
GECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTVADTYNITDPEEVETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELELELELEPENMESVPLDPSASSASL
PLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4122 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtggggactcgtgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggcccggcattgacatccgc
aacgactaccagcagctgaagcgcctggaaaactgcacagtgattgagggcttcctccac
atcctgctcatctccaaggccgaggactaccgaagctaccgctttcccaagctcacagtc
atcaccgagtacttgctgctgtttcgagtggccggcctcgagagcctgggagacctcttc
cccaacctcacagtcatccgtggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttataacctgaggaacattacgcggggggcc
atcaggattgagaagaatgctgacctctgttacctctccactatagactggtctctcatt
ttggatgcagtgtccaataactacattgtggggaacaagcccccaaaggaatgcggggac
ctgtgtcctgggaccttggaggagaagcccatgtgtgagaagaccaccatcaacaacgag
tacaactaccgctgctggaccacaaatcactgccagaaaatgtgcccaagcgtgtgcgga
aagcgagcctgcaccgagaacaatgaatgttgccacccagagtgcctgggcagctgccat
acacccgacgacaacaccacctgtgtggcctgccgacactactactacaaaggcgtgtgt
gtgcctgcctgcccgctgggcacctacaggttcgagggctggcgctgtgtggaccgcgac
ttctgcgccaacatccccaacgccgagagcagcgactccgatggctttgtcatccacgac
ggcgagtgcatgcaagagtgtccctcaggcttcatccgcaacagcacccagagcatgtac
tgcatcccctgtgaaggcccctgccctaaagtctgtggtgatgaagaaaagaaaacaaaa
accattgattcagtgacgtcggctcagatgcttcaaggttgcaccatcttgaagggcaac
ttgcttatcaacatccggcgaggcaataacattgcctcagaactggagaacttcatgggc
ctcatcgaggtggtgaccggctatgtgaagatccgccattcccatgctttggtctccttg
tccttcctgaagaaccttcgcctaatcttaggagaggagcagctggaagggaactactcc
ttctatgtgctggacaaccagaacttgcagcagctgtgggactggaaccaccggaacctg
accgtcaggtcggggaagatgtactttgctttcaatcccaagctgtgtgtctctgaaatc
taccgcatggaggaagtcacaggaacaaagggccgccagagcaaaggggacataaacacc
aggaacaacggagagcgagcttcctgtgaaagtgacgttctccgtttcacatctaccacc
acctcaaagaaccgcatcatcataacctggcaccggtaccggcccccagactacagggat
cttatcagcttcacagtttactacaaggaggcaccctttaaaaacgttactgaatacgat
ggacaggatgcctgtggctccaacagctggaacatggtggatgtggacctgcctcccaac
aaggagggggagcctggcattttactgcatgggctgaagccctggacccagtatgctgtt
tatgtcaaggctgtgaccctcaccatggtggaaaacgaccatatccgtggggccaaaagt
gaaatcttgtacattcgcaccaatgcatcagttccttccattcccctagacgttctttcc
gcgtcaaactcctcttctcagctgattgtgaagtggaaccccccaactctgcccaacggt
aacttgagttactacattgtgaggtggcagcggcagccacaggatggctatctgtaccgg
cacaactactgttccaaagacaaaatacccatcagaaagtacgcggatggcaccatcgat
gtggaagaggtgaccgagaaccccaagacagaagtgtgtggtggtgacaaagggccttgc
tgtgcttgtcccaaaaccgaagccgagaagcaggccgagaaggaagaggctgagtaccgc
aaggtctttgagaatttccttcacaattccatcttcgtgcccagacccgaaaggaagcgg
agagatgtcatgcaagtggccaacaccaccatgtctagccgaagcaggaacaccacagtg
gcagacacctacaatatcacagacccggaagaagtcgagacagaataccctttctttgag
agcagggtggataacaaggagagaactgtcatttccaacctccggcctttcactttgtac
cgtatcgatatccacagctgcaaccatgaagctgagaagctgggctgcagtgcctccaac
ttcgtctttgcgagaaccatgcctgcagaaggagcagatgacattcctggaccagtgacc
tgggagccaagaccggagaactccatcttcttaaagtggccagaacccgagaaccctaat
ggattgatcctaatgtatgaaataaagtacggatcacaagttgaggatcagcgggaatgt
gtgtccagacaggagtacaggaagtatggaggggccaagcttaaccggctaaacccaggg
aactatacagcccggattcaagccacctctctctctggcaatgggtcgtggacagatcct
gtgttcttctatgtcccagccaagacgacgtatgagaacttcatgcatctgatcatcgct
ctgccagtagccatcctgctgattgtgggaggactggtaatcatgctgtatgtcttccat
agaaagagaaacaacagcaggttgggcaatggagtgctgtatgcctctgtgaaccccgag
tatttcagcgcagctgacgtgtatgtgcctgatgaatgggaggtcgcacgagagaagatc
accatgaaccgggagcttggacaagggtccttcgggatggtctatgaaggagtggccaag
ggtgtggtcaaggatgaacctgaaaccagagtagccatcaagacggtgaatgaagctgca
agcatgcgcgaaagaattgagtttctcaacgaggcctcggtgatgaaggagttcaactgt
caccatgtggttcgcttgctgggtgtggtgtcccaaggccagcccaccctggtcatcatg
gaactaatgacgcgtggggatctcaaaagttatctccggtctctaaggccagaagtggag
cagaataatctggtcctgattcctccgagcttaagcaagatgatccagatggctggagag
attgcagacggcatggcgtacctcaatgccaacaagtttgtccacagagaccttgctgct
cggaactgtatggtggctgaagatttcacagtcaaaattggagattttggtatgacacga
gacatctacgagacagactactaccggaaaggagggaaggggctgctgcctgtgcgctgg
atgtctcccgagtccctcaaggatggagtcttcactactcactcagatgtctggtccttt
ggggtcgtcctctgggagattgccacgttggctgagcagccatatcaaggcttgtccaac
gagcaagttcttcgcttcgtcatggagggcggccttctggacaagccggacaactgccct
gacatgctgtttgaactgatgcgcatgtgctggcagtataaccctaagatgcggccctcc
ttcctggagatcattggcagcatcaaggacgagatggagcccagctttcaagaggtctcc
ttctactacagcgaggagaacaagcctcctgagccagaggagctggagctggagctggag
ctggagcccgagaacatggagagtgtaccgctggacccctcggcctcctccgcctccctg
cctctgcctgaaagacactcaggacacaaggccgagaatggcccgggccctggagtactg
gttctccgcgccagtttcgatgagagacagccttacgctcacatgaacgggggacgcgcc
aatgagagggctttgcctctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
