KEGG   Microtus oregoni (creeping vole): 121454539
Entry
121454539         CDS       T08307                                 
Symbol
Ppp1ca
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg03015  mRNA surveillance pathway
morg04022  cGMP-PKG signaling pathway
morg04024  cAMP signaling pathway
morg04114  Oocyte meiosis
morg04218  Cellular senescence
morg04261  Adrenergic signaling in cardiomyocytes
morg04270  Vascular smooth muscle contraction
morg04390  Hippo signaling pathway
morg04510  Focal adhesion
morg04611  Platelet activation
morg04720  Long-term potentiation
morg04728  Dopaminergic synapse
morg04750  Inflammatory mediator regulation of TRP channels
morg04810  Regulation of actin cytoskeleton
morg04910  Insulin signaling pathway
morg04921  Oxytocin signaling pathway
morg04931  Insulin resistance
morg05031  Amphetamine addiction
morg05034  Alcoholism
morg05168  Herpes simplex virus 1 infection
morg05205  Proteoglycans in cancer
morg05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:morg00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    121454539 (Ppp1ca)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    121454539 (Ppp1ca)
   04024 cAMP signaling pathway
    121454539 (Ppp1ca)
   04022 cGMP-PKG signaling pathway
    121454539 (Ppp1ca)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121454539 (Ppp1ca)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    121454539 (Ppp1ca)
  09156 Nervous system
   04728 Dopaminergic synapse
    121454539 (Ppp1ca)
   04720 Long-term potentiation
    121454539 (Ppp1ca)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    121454539 (Ppp1ca)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    121454539 (Ppp1ca)
  09165 Substance dependence
   05031 Amphetamine addiction
    121454539 (Ppp1ca)
   05034 Alcoholism
    121454539 (Ppp1ca)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    121454539 (Ppp1ca)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    121454539 (Ppp1ca)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:morg01009]
    121454539 (Ppp1ca)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:morg03021]
    121454539 (Ppp1ca)
   03019 Messenger RNA biogenesis [BR:morg03019]
    121454539 (Ppp1ca)
   03041 Spliceosome [BR:morg03041]
    121454539 (Ppp1ca)
Enzymes [BR:morg01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     121454539 (Ppp1ca)
Protein phosphatases and associated proteins [BR:morg01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     121454539 (Ppp1ca)
Transcription machinery [BR:morg03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     121454539 (Ppp1ca)
Messenger RNA biogenesis [BR:morg03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     121454539 (Ppp1ca)
Spliceosome [BR:morg03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    121454539 (Ppp1ca)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 121454539
NCBI-ProteinID: XP_041517869
LinkDB
Position
Unknown
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactccatcatcgggcgcctgctggaagtgcag
ggctcacggcctggaaagaatgtgcaactaacagagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcctattcttctggagcttgaggcgcctctcaag
atctgcggtgacatccatggccagtactatgaccttctacggctgtttgagtatggtggc
ttccccccagagagcaactaccttttcttgggggactatgtggaccgtggcaagcagtct
ttggagaccatctgcctgctgctggcctataagatcaaataccctgagaatttctttctg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctacggcttctatgatgaatgc
aagagacgctacaacatcaaactgtggaaaacgttcaccgactgcttcaactgcttgccc
attgcagccattgtagacgagaagatcttctgctgccacggaggcctgtctccagacttg
cagtccatggagcagatcaggcgtattatgcggcccacagacgtgcctgaccagggcctc
ctgtgtgatctgctgtggtctgaccctgacaaggatgttcaaggctggggcgagaatgac
cgtggtgtctccttcacctttggggcggaggtggtggccaagttcctgcacaagcatgat
ttggacctcatctgccgggcgcaccaggttgtagaagatggctatgagttctttgccaag
aggcagttggtgacactcttctctgctcccaactactgtggcgagtttgacaatgccggt
gccatgatgagcgtggatgagacccttatgtgctccttccagatcctcaagcccgctgac
aagaacaaggggaagtatgggcagttcagtggcctgaaccctggaggccgtcccatcacc
ccaccccgcaattctgccaaagccaagaaatag

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