KEGG   Microtus oregoni (creeping vole): 121455025
Entry
121455025         CDS       T08307                                 
Symbol
Mapk8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01522  Endocrine resistance
morg04010  MAPK signaling pathway
morg04012  ErbB signaling pathway
morg04014  Ras signaling pathway
morg04024  cAMP signaling pathway
morg04068  FoxO signaling pathway
morg04071  Sphingolipid signaling pathway
morg04137  Mitophagy - animal
morg04140  Autophagy - animal
morg04141  Protein processing in endoplasmic reticulum
morg04210  Apoptosis
morg04215  Apoptosis - multiple species
morg04217  Necroptosis
morg04310  Wnt signaling pathway
morg04380  Osteoclast differentiation
morg04510  Focal adhesion
morg04530  Tight junction
morg04620  Toll-like receptor signaling pathway
morg04621  NOD-like receptor signaling pathway
morg04622  RIG-I-like receptor signaling pathway
morg04625  C-type lectin receptor signaling pathway
morg04657  IL-17 signaling pathway
morg04658  Th1 and Th2 cell differentiation
morg04659  Th17 cell differentiation
morg04660  T cell receptor signaling pathway
morg04664  Fc epsilon RI signaling pathway
morg04668  TNF signaling pathway
morg04722  Neurotrophin signaling pathway
morg04723  Retrograde endocannabinoid signaling
morg04728  Dopaminergic synapse
morg04750  Inflammatory mediator regulation of TRP channels
morg04910  Insulin signaling pathway
morg04912  GnRH signaling pathway
morg04914  Progesterone-mediated oocyte maturation
morg04917  Prolactin signaling pathway
morg04920  Adipocytokine signaling pathway
morg04926  Relaxin signaling pathway
morg04930  Type II diabetes mellitus
morg04931  Insulin resistance
morg04932  Non-alcoholic fatty liver disease
morg04933  AGE-RAGE signaling pathway in diabetic complications
morg04935  Growth hormone synthesis, secretion and action
morg04936  Alcoholic liver disease
morg05010  Alzheimer disease
morg05012  Parkinson disease
morg05016  Huntington disease
morg05017  Spinocerebellar ataxia
morg05020  Prion disease
morg05022  Pathways of neurodegeneration - multiple diseases
morg05132  Salmonella infection
morg05133  Pertussis
morg05135  Yersinia infection
morg05142  Chagas disease
morg05145  Toxoplasmosis
morg05152  Tuberculosis
morg05161  Hepatitis B
morg05162  Measles
morg05166  Human T-cell leukemia virus 1 infection
morg05167  Kaposi sarcoma-associated herpesvirus infection
morg05169  Epstein-Barr virus infection
morg05170  Human immunodeficiency virus 1 infection
morg05171  Coronavirus disease - COVID-19
morg05200  Pathways in cancer
morg05208  Chemical carcinogenesis - reactive oxygen species
morg05210  Colorectal cancer
morg05212  Pancreatic cancer
morg05231  Choline metabolism in cancer
morg05415  Diabetic cardiomyopathy
morg05417  Lipid and atherosclerosis
morg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:morg00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    121455025 (Mapk8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121455025 (Mapk8)
   04012 ErbB signaling pathway
    121455025 (Mapk8)
   04014 Ras signaling pathway
    121455025 (Mapk8)
   04310 Wnt signaling pathway
    121455025 (Mapk8)
   04668 TNF signaling pathway
    121455025 (Mapk8)
   04068 FoxO signaling pathway
    121455025 (Mapk8)
   04071 Sphingolipid signaling pathway
    121455025 (Mapk8)
   04024 cAMP signaling pathway
    121455025 (Mapk8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    121455025 (Mapk8)
   04137 Mitophagy - animal
    121455025 (Mapk8)
  09143 Cell growth and death
   04210 Apoptosis
    121455025 (Mapk8)
   04215 Apoptosis - multiple species
    121455025 (Mapk8)
   04217 Necroptosis
    121455025 (Mapk8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121455025 (Mapk8)
   04530 Tight junction
    121455025 (Mapk8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    121455025 (Mapk8)
   04621 NOD-like receptor signaling pathway
    121455025 (Mapk8)
   04622 RIG-I-like receptor signaling pathway
    121455025 (Mapk8)
   04625 C-type lectin receptor signaling pathway
    121455025 (Mapk8)
   04660 T cell receptor signaling pathway
    121455025 (Mapk8)
   04658 Th1 and Th2 cell differentiation
    121455025 (Mapk8)
   04659 Th17 cell differentiation
    121455025 (Mapk8)
   04657 IL-17 signaling pathway
    121455025 (Mapk8)
   04664 Fc epsilon RI signaling pathway
    121455025 (Mapk8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    121455025 (Mapk8)
   04920 Adipocytokine signaling pathway
    121455025 (Mapk8)
   04912 GnRH signaling pathway
    121455025 (Mapk8)
   04914 Progesterone-mediated oocyte maturation
    121455025 (Mapk8)
   04917 Prolactin signaling pathway
    121455025 (Mapk8)
   04926 Relaxin signaling pathway
    121455025 (Mapk8)
   04935 Growth hormone synthesis, secretion and action
    121455025 (Mapk8)
  09156 Nervous system
   04728 Dopaminergic synapse
    121455025 (Mapk8)
   04723 Retrograde endocannabinoid signaling
    121455025 (Mapk8)
   04722 Neurotrophin signaling pathway
    121455025 (Mapk8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    121455025 (Mapk8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121455025 (Mapk8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121455025 (Mapk8)
   05208 Chemical carcinogenesis - reactive oxygen species
    121455025 (Mapk8)
   05231 Choline metabolism in cancer
    121455025 (Mapk8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    121455025 (Mapk8)
   05212 Pancreatic cancer
    121455025 (Mapk8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121455025 (Mapk8)
   05170 Human immunodeficiency virus 1 infection
    121455025 (Mapk8)
   05161 Hepatitis B
    121455025 (Mapk8)
   05171 Coronavirus disease - COVID-19
    121455025 (Mapk8)
   05162 Measles
    121455025 (Mapk8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121455025 (Mapk8)
   05169 Epstein-Barr virus infection
    121455025 (Mapk8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    121455025 (Mapk8)
   05135 Yersinia infection
    121455025 (Mapk8)
   05133 Pertussis
    121455025 (Mapk8)
   05152 Tuberculosis
    121455025 (Mapk8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    121455025 (Mapk8)
   05142 Chagas disease
    121455025 (Mapk8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121455025 (Mapk8)
   05012 Parkinson disease
    121455025 (Mapk8)
   05016 Huntington disease
    121455025 (Mapk8)
   05017 Spinocerebellar ataxia
    121455025 (Mapk8)
   05020 Prion disease
    121455025 (Mapk8)
   05022 Pathways of neurodegeneration - multiple diseases
    121455025 (Mapk8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121455025 (Mapk8)
   05418 Fluid shear stress and atherosclerosis
    121455025 (Mapk8)
   05415 Diabetic cardiomyopathy
    121455025 (Mapk8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    121455025 (Mapk8)
   04936 Alcoholic liver disease
    121455025 (Mapk8)
   04932 Non-alcoholic fatty liver disease
    121455025 (Mapk8)
   04931 Insulin resistance
    121455025 (Mapk8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    121455025 (Mapk8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    121455025 (Mapk8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:morg01001]
    121455025 (Mapk8)
Enzymes [BR:morg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     121455025 (Mapk8)
Protein kinases [BR:morg01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   121455025 (Mapk8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 121455025
NCBI-ProteinID: XP_041518447
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSPSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttttatagtgtagagattggagattctacattc
acagtcctaaaacgataccagaatttaaaacctataggctcaggagctcaaggaatagtg
tgtgcagcttatgatgccattctcgaaagaaatgttgcaatcaagaagctcagccggcca
tttcagaatcagactcatgctaaacgagcctaccgagaactagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagttagatcatgaaagaatgtcctaccttctctatcaaatgctgtgtggaatcaag
caccttcactctgctggaattattcaccgggacttaaagcctagtaatatagtagtcaaa
tcagactgcactttgaagattcttgattttggactggcgaggactgcaggaacaagtttt
atgatgacgccttatgtcgtgactcggtactacagagcgccagaggtcatcctcggcatg
ggctacaaggagaacgtggatttatggtctgtggggtgcattatgggagaaatggtttgc
cacaaaatcctctttccaggaagggactatattgatcagtggaataaagttattgaacag
cttggaacaccctgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaaccgacctaaatatgctggatatagttttgagaaactgttccctgatgtgcttttc
ccagctgactcagagcataacaagcttaaagccagtcaagcaagggatttgttatccaaa
atgctagtaatagatgcatccaaaaggatctcagtagatgaagctctccagcacccatac
atcaacgtctggtatgacccttcggaagcagaagccccaccaccaaagatccctgacaag
cagttagatgaaagggagcacacaatagaagagtggaaagaattaatatacaaggaggtg
atggacttggaggaaagaaccaagaatggagtcataagagggcagccatctcctttaggt
gcagcagtgatcaacggctctcagcacccatcgtcttcaccgtctgtcaatgatgtgtct
tcaatgtccacagatccgactttggcctcggatacagacagcagtctagaagcatctgct
ggacctctaggctgctgtagatga

DBGET integrated database retrieval system