Microtus oregoni (creeping vole): 121455292 Help Entry 121455292         CDS       T08307                                  Symbol Top2b Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism morg  Microtus oregoni (creeping vole) Pathway morg01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:morg00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     121455292 (Top2b)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:morg03032]     121455292 (Top2b)    03036 Chromosome and associated proteins [BR:morg03036]     121455292 (Top2b) Enzymes [BR:morg01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      121455292 (Top2b) DNA replication proteins [BR:morg03032]  Eukaryotic type   DNA Topoisomerases    121455292 (Top2b) Chromosome and associated proteins [BR:morg03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     121455292 (Top2b)   Centrosome formation proteins    Centriole proteins     121455292 (Top2b) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c Motif Other DBs NCBI-GeneID:  121455292 NCBI-ProteinID:  XP_041518877 LinkDB All DBs Position Unknown AA seq 1612 aa AA seqDB search MAKTSLAGADGALTWVNNAAKKEELETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYI GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKL DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPN YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK DLIQMLVQRGYESDPVRAWKEAQEKAAEEEDTQNQHDDSSSDSGTPSGPDFNYILNMSLW SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTAAVKT EFDEEFSGTPVEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKPNAKKVKKR NPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDIE ELKVKASPVTNDGEDEFVPSDGLDKDEYAFSPGKSKATPEKSSHDKKSQDFGNLFSFPSY SQKSEDDSAKFDSNEEDTASVFAPSFGLKQADKVPSKTVAAKKGKPPSDTAPKAKRAPKQ KKVVETVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKPSKPASKKLK KTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFS NT seq 4839 nt NT seq  +upstreamnt  +downstreamnt atggccaagaccagcctcgcgggtgctgatggggcgctgacctgggtgaacaatgctgca aaaaaggaagaattggaaacagcaaacaaaaatgattcttcaaagaagttgtctgttgag agagtgtaccagaagaagacccaacttgaacatattctcctccgtcctgatacatacatt ggatccgtagaaccattgacccagttgatgtgggtgtatgatgaagatgtaggaatgaac tgcagagaggttacctttgttccaggcttatacaagatctttgatgaaattttggtcaat gctgctgacaataagcagagggacaagaacatgacctgtattaaggtttctattgatcct gaatctaatattataagcatttggaataatgggaaaggcattccagtagtagaacacaaa gtagagaaagtttatgttcctgctttgatctttggacagcttttaacatcgagtaattat gatgatgatgagaaaaaagttacagggggccgtaatggttatggtgcaaaactttgtaat atttttagtacaaagtttacagtagaaacggcttgcaaagaatacaaacatagttttaag cagacatggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggt gaagattatacatgtataacattccaaccagatctatccaagtttaagatggaaaaactt gacaaagacattgtggccctcatgactagaagagcatatgatttggctggttcatgtaaa ggggtcaaggtcatgttcaatggaaagaagttgcctgtaaatggatttcgcagctacgta gacctttatgtgaaagacaaattggatgaaactggggtagccctcaaagttatccatgaa cttgcaaatgaaagatgggatgtttgcctcaccttgagtgagaaagggttccagcagatc agctttgtgaatagtattgcaactacaaaaggtggacggcatgtggattacgtagtagat caagttgttggtaaactgattgaagtagttaagaaaaagaacaaagctggtgtatcagtg aagccatttcaagttaaaaaccatatatgggtttttattaattgtcttattgaaaatcca acctttgattctcaaactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa tgccaactgtcagaaaagttttttaaagcagcctctaattgtggcattgtagaaagcata ttgaactgggtgaaatttaaggctcagactcagctgaataagaagtgttcatcagtaaaa tacagtaaaatcaaaggtattcccaagctggatgatgccaatgatgctggtggcaaacat tccctggagtgtacattgatattaacagagggggactctgccaaatcgctggctgtatct ggattaggtgtgatcgggagggacagatacggagtcttcccactcaggggtaaaattctc aatgtgcgagaagcgtctcataagcagattatggaaaatgcagaaataaacaatattatt aaaatagttggcttacaatacaagaaaagttatgatgatgcagaatctctgaaaacctta cgttatggaaagattatgattatgactgatcaggatcaagatggttctcacatcaaaggc cttctaatcaattttattcatcacaattggccatcactcttgaagcatggttttcttgaa gaattcattactcccattgtaaaggcaagcaaaaataagcaggaactttccttttatagt attcctgaatttgatgaatggaaaaaacatatagaaaaccagaaagcctggaaaataaaa tactacaaaggattgggtaccagtacagctaaagaagcaaaggaatattttgctgatatg gaaaggcatcgtattttgtttagatatgctggccctgaagatgatgctgccattaccttg gcattcagtaagaagaagattgatgacaggaaagaatggttaacaaactttatggaggat cggagacagcgtaggttacatggcctaccagagcaatttttgtatggtacggcaacaaag cacttgacgtacaatgacttcatcaacaaggaattgattctcttctcaaactcagacaat gagagatctataccgtctcttgtggatggcttcaaaccaggccagcgaaaagttttgttt acctgtttcaagaggaatgataaacgtgaagtcaaagttgcccagctggctggatctgtt gctgaaatgtctgcttatcatcatggagaacaagcattgatgatgactattgtgaatttg gctcagaattttgtgggcagtaacaacattaacttgcttcagcccattggtcagtttgga actcggcttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttaagc tctctggcaagactgctttttccggccgtggatgataacttacttaagttcctttatgat gataatcagcgtgtggagcccgagtggtacatccccataatccctatggttttgattaat ggtgctgagggcattgggactggatgggcttgtaaactgcccaactatgatgctagagaa attgtgaacaatgtcagacggatgctagagggtttggaccctcatcccatgcttccaaac tataaaaactttaaaggcaccatccaggaacttggtcagaaccagtatgctgtcagtggt gagatatttgtggtggatagaaacacagtagagattacagaacttcctgttagaacttgg acccaggtatacaaggagcaggtcctggaacctatgcttaatggaacagataaaacacca gctctaatttctgattacaaagaatatcatactgatacaactgtgaaatttgtggtaaaa atgacggaagagaaacttgcacaagcagaagctgctggactgcataaagtttttaaactt cagactactctgacttgtaattccatggtactctttgatcatatgggatgtctgaagaag tatgaaactgtgcaagacattctgaaggaattctttgatttacgattaagttattatggt ttacggaaggaatggcttgtaggaatgttgggagcagaatctacaaagcttaataatcaa gcccgtttcattttagagaagatacaaggaaaaattactattgagaataggtcaaagaaa gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgagagcgtggaaa gaagcacaagaaaaggcagctgaagaggaagacactcaaaaccaacatgatgacagttcc tctgactcaggaactccttcaggccctgactttaattatattttaaatatgtctctgtgg tctcttactaaagagaaagttgaagaactcattaagcagagagatacaaaagggcgagaa gttaatgatctcaaaaggaaatctccttcagacctttggaaagaagatttagcagcattt gttgaagaactggataaagtggaagcacaagaacgagaagatattctggcaggaatgtct ggaaaagcaataaaaggtaaagttggcaaacctaaggtaaagaaacttcagctggaggag acgatgccctcaccttatgggagaagaattgttcctgaaattactgctatgaaggcagat gccagcagaaaattgctgaagaagaagaagggtgatcctgataccgcagcagtgaaaaca gaatttgatgaagaatttagtggaacaccagtagaaggtacaggagaagagacactgacc ccatcagctcctgtaaataaaggtcccaaacccaaaagggagaaaaaggagcctggtacc agggttagaaaaacacccacctcatctggtaaaccaaatgcaaaaaaagtgaagaagcga aacccttggtcagatgatgagtccaagtcggagagtgacttggaagaaacagaacctgtg gttattccaagagattctttgctgaggagagcagctgctgaaagacctaagtataccttt gatttctcggaagaagaagatgacgatgctgatgatgatgatgacaataatgacatagaa gaactgaaagttaaagcatctcccgtaactaatgatggggaagatgagttcgttccttca gatggcttagataaagatgagtatgctttttctccaggcaaatcaaaagctactccagaa aaatcgtcacatgacaaaaaaagtcaggattttgggaatctcttttcatttccttcatat tctcagaagtcagaagatgattcagctaaatttgacagcaatgaagaagatactgcttct gtttttgcaccatcatttggtctgaagcaagcagataaagttccaagtaaaacagttgct gctaaaaagggtaaaccaccttcagatacagcccctaaggcgaagagagcacctaaacag aagaaagtcgtagaaactgtaaactctgactctgattctgaatttggcattccaaagaag actacaacaccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatcaggctcagaa aatgaaggtgattataaccctgggagaaaaccatctaaaccagccagcaagaagctgaag aaaacatcttttgatcaggattcagatgtagacatcttcccctcggacttcacttctgaa ccacctgctctgccacggactggtcgggctaggaaagaagtaaaatattttgcagagtct gatgaagaagaagatgttgattttgcaatgtttagttaa

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