Microtus oregoni (creeping vole): 121456855 Help Entry 121456855         CDS       T08307                                  Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism morg  Microtus oregoni (creeping vole) Pathway morg01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:morg00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     121456855  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:morg03032]     121456855    03036 Chromosome and associated proteins [BR:morg03036]     121456855 Enzymes [BR:morg01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      121456855 DNA replication proteins [BR:morg03032]  Eukaryotic type   DNA Topoisomerases    121456855 Chromosome and associated proteins [BR:morg03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     121456855   Centrosome formation proteins    Centriole proteins     121456855 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  121456855 NCBI-ProteinID:  XP_041521277 LinkDB All DBs Position Unknown AA seq 1529 aa AA seqDB search MELSPLQPVNENMQMNKKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET ASKEYKKMFKQTWMDNMGRAGDMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVR RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNALKVIHEQVNPRWEVCL TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGIAVKAHQVKNHMW IFVNCLIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQI QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQELAFYSLPEFEEWKSS TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR KEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPLKDDHTLKFLYDDNQRVEPEWY IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE LASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH TDTTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVVDILKD FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG YDSDPVKAWKEAQQKVPDEEENEESDNENSDSTADSGPTFNYLLDMPLWYLTKEKKDELC KQRNEKEQELNTLKKKSPSDLWKEDLAVFIEELEVVENKEKQDEQVGLPGKGGKAKGKKA QTSEVLPSPRGKRVIPQVTMEMKAEAEKKIRKKIKSENVEGTPTEDGQELGGLKQRLEKK QRQKKEPGTMAKKQTTLPFKPIRKGKKRNPWSDSESDMSSNESHFDVPPREKEPRRATTK AKFTEDLDSDEDFSGFDEKDEDEDFFPLDTSPPKTKIPPKNTKKALKPQKSTMSVDLEGD VKDGVPASPGSAAADFPAETEQLKPSSKQTAAVKKTVAKSQSSTSTAAATKKRAAPKGTK SDSTLSAHGPEKPDPAKAKSSRKRKQSSSDDSDSDFEKLTSKASVSKKSKGENQDFHVDL DETVAPRAKSGRARKPIKYLEESDEDDLF NT seq 4590 nt NT seq  +upstreamnt  +downstreamnt atggagttatctccgctgcagcctgtaaatgaaaatatgcagatgaacaaaaagaaaaat gaagatgccaagaagagactatctattgaaagaatctatcagaaaaaaacacaattggaa catatattgctccgcccagatacctacattggctctgtggaattagttacccagcaaatg tgggtttatgatgaagatgttggcattaactatagggaagtaacttttgttcctggtttg tataaaatcttcgatgagattctagtcaatgcggcagacaacaaacaaagggaccccaaa atgtcttgtattagagtcacaattgatccagaaaataatttaattagtatatggaataat ggaaaaggaattcctgttgttgaacacaaagttgagaaaatgtatgtcccagctctcata tttggacagctcttaacctctagtaactacgatgatgatgaaaagaaagtaacaggtggt cgaaatggctatggagccaaactgtgtaatatattcagcaccaaatttactgtggaaaca gccagtaaagaatataagaaaatgttcaaacagacatggatggataacatggggagagct ggtgacatggaactcaagccctttaatggagaagattatacatgtattacctttcaacct gatttatctaagtttaaaatgcaaagtctggataaagatattgttgcactgatggttaga agagcatatgatattgctggttccactaaagatgtcaaagtcttccttaatggaaataag ctgccagtaaaaggattccgcagctatgtggatatgtacttgaaggataaggtagatgaa actgggaacgcactgaaagtcatacacgaacaagtcaacccacggtgggaagtgtgctta acaatgagtgaaaagggctttcagcaaattagctttgtcaatagcattgcgacttctaag ggtggcagacatgttgattatgtagctgatcagatcgtgagtaaacttgtcgatgtggtg aagaagaagaacaagggtggaattgccgtgaaagcacaccaggtgaaaaatcacatgtgg atttttgtaaattgcttgattgaaaatccaacctttgactctcagacgaaagaaaacatg actttacaagccaagagctttggatcaacatgtcaattaagtgaaaaattcatcaaagct gcaattggctgtggtattgttgaaagcatactaaactgggtgaagtttaaggcccaaatc cagttaaacaagaagtgttcagctgtaaagcataacagaatcaagggaatcccaaaactt gatgacgccaacgatgcagggagtcgaaattccactgaatgtacacttatcctgactgag ggagactcagccaaaactctggcagtttcaggtcttggtgtagttggaagagacaaatat ggggtatttcctcttagaggaaaaatactcaatgtgcgagaagcttctcataaacagatt atggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaaaac tatgaagatgaagattcattgaaaactcttcgttatgggaagataatgattatgacagat caggaccaagatggttcccatatcaaaggcttactgatcaattttatccatcacaactgg ccctctcttctgcgacatcgttttctagaggaatttattactcctattgtaaaggtgtct aaaaacaagcaagaattggcattctatagtcttcctgagtttgaagaatggaagagttct actccaaatcataagaaatggaaagtcaaatattacaaaggtttggggaccagcacgtca aaggaagctaaggaatattttgcagatatgaaaagacatcgtattcaattcaaatactct gggcctgaagatgatgctgcaatcagcctggcctttagtaagaaacaggtcgatgatcga aaggaatggttaactcatttcatggaagacaggcgacagcggaaattacttggtcttcct gaggattatttgtatggacaaaccaccacttacctgacctataatgacttcataaacaag gaacttatcctgttctcaaattctgataatgaaagatctattccatctatggtagatggt ttgaaaccagggcagagaaaggttttatttacttgtttcaaacggaatgacaagcgagaa gtgaaggttgcccagttagctgggtcagtggcagaaatgtcctcttatcaccatggtgag atgtcactgatgatgaccattatcaatttggctcagaattttgtgggcagtaataatttg aacctcttgcaacccattggtcagtttggtaccaggctgcatggtggcaaggattcggct agtcctcgatacatctttactatgcttagccctttgactcggttgttatttccactgaaa gatgatcacacattgaagtttttatatgatgacaaccaacgtgttgagcctgaatggtac attcctattatacctatggtgctgataaatggcgccgaaggaattggtaccgggtggtcc tgcaaaatccccaattttgatgtccgtgaagtcgtaaataatatcagacgactgttggat ggagaagagcctctgcccatgctcccaagttacaagaatttcaaaggtactattgaagaa ctggcttcaaatcagtatgtgattagtggagaagtagcaattctgaattccacaaccatt gaaatctcagagcttcccatcagaacatggacccagacttacaaagaacaagttctagaa cccatgttgaatggcactgagaagacaccccctcttataacagattatagggaataccat acagacaccactgtgaagttcgtcataaagatgactgaagagaaattggcagaggcagag agagtgggactacacaaagtcttcaaactgcagactagcctcacttgcaactcaatggtg ctttttgaccatgtaggttgcttaaagaagtatgatactgtggtggatattctaaaggac ttctttgagctcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt ggtgcagaatctgctaaactgaataatcaagctcgttttatactagagaaaatagacggc aaaataatcattgaaaataaacctaaaaaagagttaattaaagttctaattcagagagga tatgattctgatcctgtgaaagcctggaaagaagctcagcaaaaggttccagatgaagaa gaaaatgaagaaagtgacaatgaaaacagtgactccacagcagactctggaccaactttc aactaccttctggatatgcccctctggtatctaaccaaggaaaagaaggatgagctgtgc aaacaaagaaatgaaaaggaacaagagcttaacacattaaagaaaaagagtccatcagat ttgtggaaggaggatctggctgtttttattgaagaactggaggttgttgaaaacaaggaa aaacaagatgaacaagtaggacttcctggaaagggagggaaggcgaaggggaagaaagca caaacgtctgaagtcttgccttctcctcgaggaaaaagagttattccccaagtgaccatg gagatgaaagcagaggcagaaaagaaaattaggaagaaaattaagagtgaaaatgttgag ggcacgcctactgaggatggtcaggaactaggaggccttaaacaaagactagagaagaag cagaggcagaagaaagagccaggtaccatggcaaagaagcaaactacattgccatttaag cccatcagaaaaggaaaaaagagaaacccttggtccgattctgaatcagatatgagcagt aatgaaagtcattttgatgttcctccacgagaaaaagaaccacgaagagctacaacaaaa gccaaatttacagaggatttggattcagatgaagatttctcaggttttgatgaaaaggat gaagatgaagattttttcccattagatactagtccacctaagaccaaaattccaccaaaa aatactaaaaaagcactgaagccacagaaaagtaccatgtctgttgaccttgaaggtgat gtgaaggacggtgtaccagcttctccaggctctgctgctgctgacttcccagctgaaact gagcagttaaagccatcttccaaacagactgcagcagtgaagaagacagtagccaaatcc cagtcttcaacctccactgctgctgctactaaaaagagagctgcaccaaagggaaccaaa tcagattcaaccttgagtgctcatggccctgaaaagcctgatcctgccaaagctaagagc agccgcaaaaggaagcagtcttcttctgacgattctgattctgattttgagaaactaact tccaaagcttccgtgagcaagaaatccaagggagagaatcaggatttccatgtggactta gacgagactgtggctcctcgagcaaaatctggacgagcaaggaagcctattaagtacctg gaggagtcagatgaggacgatcttttctga

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