KEGG   Microtus oregoni (creeping vole): 121457121
Entry
121457121         CDS       T08307                                 
Symbol
Rps6kb1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01521  EGFR tyrosine kinase inhibitor resistance
morg01522  Endocrine resistance
morg04012  ErbB signaling pathway
morg04066  HIF-1 signaling pathway
morg04140  Autophagy - animal
morg04150  mTOR signaling pathway
morg04151  PI3K-Akt signaling pathway
morg04152  AMPK signaling pathway
morg04211  Longevity regulating pathway
morg04213  Longevity regulating pathway - multiple species
morg04350  TGF-beta signaling pathway
morg04371  Apelin signaling pathway
morg04666  Fc gamma R-mediated phagosome formation
morg04714  Thermogenesis
morg04910  Insulin signaling pathway
morg04931  Insulin resistance
morg05163  Human cytomegalovirus infection
morg05165  Human papillomavirus infection
morg05170  Human immunodeficiency virus 1 infection
morg05200  Pathways in cancer
morg05205  Proteoglycans in cancer
morg05207  Chemical carcinogenesis - receptor activation
morg05210  Colorectal cancer
morg05212  Pancreatic cancer
morg05221  Acute myeloid leukemia
morg05224  Breast cancer
morg05225  Hepatocellular carcinoma
morg05226  Gastric cancer
morg05231  Choline metabolism in cancer
morg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:morg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    121457121 (Rps6kb1)
   04350 TGF-beta signaling pathway
    121457121 (Rps6kb1)
   04371 Apelin signaling pathway
    121457121 (Rps6kb1)
   04066 HIF-1 signaling pathway
    121457121 (Rps6kb1)
   04151 PI3K-Akt signaling pathway
    121457121 (Rps6kb1)
   04152 AMPK signaling pathway
    121457121 (Rps6kb1)
   04150 mTOR signaling pathway
    121457121 (Rps6kb1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    121457121 (Rps6kb1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagosome formation
    121457121 (Rps6kb1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    121457121 (Rps6kb1)
  09149 Aging
   04211 Longevity regulating pathway
    121457121 (Rps6kb1)
   04213 Longevity regulating pathway - multiple species
    121457121 (Rps6kb1)
  09159 Environmental adaptation
   04714 Thermogenesis
    121457121 (Rps6kb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121457121 (Rps6kb1)
   05205 Proteoglycans in cancer
    121457121 (Rps6kb1)
   05207 Chemical carcinogenesis - receptor activation
    121457121 (Rps6kb1)
   05231 Choline metabolism in cancer
    121457121 (Rps6kb1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121457121 (Rps6kb1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    121457121 (Rps6kb1)
   05212 Pancreatic cancer
    121457121 (Rps6kb1)
   05225 Hepatocellular carcinoma
    121457121 (Rps6kb1)
   05226 Gastric cancer
    121457121 (Rps6kb1)
   05221 Acute myeloid leukemia
    121457121 (Rps6kb1)
   05224 Breast cancer
    121457121 (Rps6kb1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    121457121 (Rps6kb1)
   05163 Human cytomegalovirus infection
    121457121 (Rps6kb1)
   05165 Human papillomavirus infection
    121457121 (Rps6kb1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    121457121 (Rps6kb1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121457121 (Rps6kb1)
   01522 Endocrine resistance
    121457121 (Rps6kb1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:morg01001]
    121457121 (Rps6kb1)
Enzymes [BR:morg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     121457121 (Rps6kb1)
Protein kinases [BR:morg01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   121457121 (Rps6kb1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 121457121
NCBI-ProteinID: XP_041521732
LinkDB
Position
Unknown
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTVSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggcttttacccagcgcctgacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcaggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaactaggcatggaacattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaatactgggaagatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagagcggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagtggaggagaacta
tttatgcagttagaaagagagggaatattcatggaagacacagcttgcttttacttggct
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaacatcatgcttaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtagattggtggagtttggga
gcattaatgtatgacatgctgactggagcacctcctttcactggagagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaacttaatttgcctccctacctcacacaagaagct
cgagatctgcttaaaaagctgctgaaaagaaacgctgcttctcgtcttggagctggtcct
ggggatgctggagaagtccaagctcatccattcttcagacacattaactgggaagaactt
ctagctcggaaggtggagcctccttttaagcctctgttgcaatctgaagaggatgtgagt
caatttgattcaaagtttacacgtcagacacctgttgacagccccgatgactcaactctc
agtgaaagtgccaaccaggtttttctgggttttacatatgtagctccatctgtgcttgaa
agtgtgaaagaaaagttttcttttgaaccaaaaatccgatcacctcgaagatttattggt
agcccacgaacgcctgtcagcccagtcaaattctctcctggggatttctggggacgaggt
gcttcagccagcacggcaaaccctcagacacctgtggagtacccaatggaaacaagtgga
atagagcagatggatgtgacagtgagcggggaagcatcagcaccacttccaatccgacag
ccgaactctgggccatacaaaaaacaagcttttcctatgatctcaaaacggccagagcac
ctgcgtatgaatctatga

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