KEGG   Microtus oregoni (creeping vole): 121460112
Entry
121460112         CDS       T08307                                 
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01521  EGFR tyrosine kinase inhibitor resistance
morg01522  Endocrine resistance
morg04012  ErbB signaling pathway
morg04015  Rap1 signaling pathway
morg04062  Chemokine signaling pathway
morg04081  Hormone signaling
morg04137  Mitophagy - animal
morg04144  Endocytosis
morg04360  Axon guidance
morg04370  VEGF signaling pathway
morg04510  Focal adhesion
morg04520  Adherens junction
morg04530  Tight junction
morg04540  Gap junction
morg04611  Platelet activation
morg04613  Neutrophil extracellular trap formation
morg04625  C-type lectin receptor signaling pathway
morg04727  GABAergic synapse
morg04750  Inflammatory mediator regulation of TRP channels
morg04810  Regulation of actin cytoskeleton
morg04912  GnRH signaling pathway
morg04915  Estrogen signaling pathway
morg04917  Prolactin signaling pathway
morg04919  Thyroid hormone signaling pathway
morg04921  Oxytocin signaling pathway
morg04926  Relaxin signaling pathway
morg05100  Bacterial invasion of epithelial cells
morg05135  Yersinia infection
morg05152  Tuberculosis
morg05161  Hepatitis B
morg05163  Human cytomegalovirus infection
morg05167  Kaposi sarcoma-associated herpesvirus infection
morg05168  Herpes simplex virus 1 infection
morg05203  Viral carcinogenesis
morg05205  Proteoglycans in cancer
morg05207  Chemical carcinogenesis - receptor activation
morg05208  Chemical carcinogenesis - reactive oxygen species
morg05219  Bladder cancer
morg05417  Lipid and atherosclerosis
morg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:morg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    121460112 (Src)
   04015 Rap1 signaling pathway
    121460112 (Src)
   04370 VEGF signaling pathway
    121460112 (Src)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    121460112 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    121460112 (Src)
   04137 Mitophagy - animal
    121460112 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121460112 (Src)
   04520 Adherens junction
    121460112 (Src)
   04530 Tight junction
    121460112 (Src)
   04540 Gap junction
    121460112 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    121460112 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121460112 (Src)
   04613 Neutrophil extracellular trap formation
    121460112 (Src)
   04625 C-type lectin receptor signaling pathway
    121460112 (Src)
   04062 Chemokine signaling pathway
    121460112 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    121460112 (Src)
   04915 Estrogen signaling pathway
    121460112 (Src)
   04917 Prolactin signaling pathway
    121460112 (Src)
   04921 Oxytocin signaling pathway
    121460112 (Src)
   04926 Relaxin signaling pathway
    121460112 (Src)
   04919 Thyroid hormone signaling pathway
    121460112 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    121460112 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    121460112 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    121460112 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    121460112 (Src)
   05207 Chemical carcinogenesis - receptor activation
    121460112 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    121460112 (Src)
   05203 Viral carcinogenesis
    121460112 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    121460112 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    121460112 (Src)
   05168 Herpes simplex virus 1 infection
    121460112 (Src)
   05163 Human cytomegalovirus infection
    121460112 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121460112 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    121460112 (Src)
   05152 Tuberculosis
    121460112 (Src)
   05100 Bacterial invasion of epithelial cells
    121460112 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121460112 (Src)
   05418 Fluid shear stress and atherosclerosis
    121460112 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121460112 (Src)
   01522 Endocrine resistance
    121460112 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:morg01001]
    121460112 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:morg04131]
    121460112 (Src)
Enzymes [BR:morg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     121460112 (Src)
Protein kinases [BR:morg01001]
 Non-receptor tyrosine kinases
  SRC family
   121460112 (Src)
Membrane trafficking [BR:morg04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    121460112 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    121460112 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    121460112 (Src)
  Macropinocytosis
   Kinases
    121460112 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 121460112
NCBI-ProteinID: XP_041526201
LinkDB
Position
Unknown
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPAENVHGPGGAFPASQTPSKPASADGHRGPSAAFVTPGAAE
PKLFGGFNTSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLSAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaagacgccagccagaggcgccgcagcctggagccc
gctgagaacgtgcacgggcctgggggcgccttccccgcttcgcagacaccgagcaagcca
gcctccgccgacggccatcgagggcctagcgccgccttcgtgaccccaggggcggccgaa
cccaagctcttcggaggcttcaatacctcggacactgtcacctccccgcagagggcgggg
cctctggcaggtggggtgaccacctttgtggccctctatgactatgagtcacggacagag
actgacctgtccttcaagaaaggagagcggctgcagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcacactcgctgagcacggggcagaccggttacatccccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtactttggcaagatcaccagacgggagtcggagcgg
ctactgctcagcgctgagaacccaagagggaccttccttgtgagggagagtgagaccaca
aaaggtgcctactgcctctctgtatctgacttcgacaatgccaagggcctcaacgtgaaa
cactacaagatccgcaaactggacagcggtggtttctacatcacctcccgcacccagttc
aacagcctgcagcagttagtggcttactactccaaacatgccgatggcctgtgccaccgc
ctcactaccgtgtgccccacgtccaagccgcagacccagggcctggccaaggatgcctgg
gagatcccccgggagtccctgcgtctggaggtcaagttgggccagggctgcttcggagag
gtgtggatgggcacctggaacggcacaacgagggttgccatcaaaaccctgaagccaggc
accatgtctccagaggccttcctgcaggaggcccaagtcatgaagaaactgaggcatgag
aaactggtgcagctgtatgccgtggtgtcggaggaacctatttacatcgtgacggagtac
atgagcaaggggagtctgctggactttctcaagggggaaacgggcaaatatctgcggcta
ccccagctggtggacatggctgctcagatcgcctcaggtatggcctatgtggagcggatg
aactacgtgcaccgggacctccgagccgccaatatcctggttggagagaatctggtgtgt
aaggtggctgactttggtctagcccgactcatagaagacaacgaatacacagcccggcaa
ggtgccaaattccccatcaagtggactgctcccgaagctgctctgtatggcagattcacc
atcaagtcagacgtgtggtcctttgggatcctgctgaccgagctcaccactaagggacgg
gtgccctaccctggaatggtgaaccgtgaggtgctggaccaggtggagcggggctaccgg
atgccttgtccccctgagtgccccgagtccctgcacgatctcatgtgccagtgttggcgg
aaggagcctgaggagcggcccaccttcgagtacctgcaggccttcctggaggattacttc
acgtccaccgagcctcagtaccagcctggggagaacctatag

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