KEGG   Microtus oregoni (creeping vole): 121461212
Entry
121461212         CDS       T08307                                 
Symbol
Mapk12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01522  Endocrine resistance
morg04010  MAPK signaling pathway
morg04015  Rap1 signaling pathway
morg04068  FoxO signaling pathway
morg04071  Sphingolipid signaling pathway
morg04114  Oocyte meiosis
morg04148  Efferocytosis
morg04218  Cellular senescence
morg04261  Adrenergic signaling in cardiomyocytes
morg04370  VEGF signaling pathway
morg04380  Osteoclast differentiation
morg04517  IgSF CAM signaling
morg04550  Signaling pathways regulating pluripotency of stem cells
morg04611  Platelet activation
morg04613  Neutrophil extracellular trap formation
morg04620  Toll-like receptor signaling pathway
morg04621  NOD-like receptor signaling pathway
morg04622  RIG-I-like receptor signaling pathway
morg04625  C-type lectin receptor signaling pathway
morg04657  IL-17 signaling pathway
morg04658  Th1 and Th2 cell differentiation
morg04659  Th17 cell differentiation
morg04660  T cell receptor signaling pathway
morg04664  Fc epsilon RI signaling pathway
morg04668  TNF signaling pathway
morg04670  Leukocyte transendothelial migration
morg04714  Thermogenesis
morg04722  Neurotrophin signaling pathway
morg04723  Retrograde endocannabinoid signaling
morg04728  Dopaminergic synapse
morg04750  Inflammatory mediator regulation of TRP channels
morg04912  GnRH signaling pathway
morg04914  Progesterone-mediated oocyte maturation
morg04917  Prolactin signaling pathway
morg04926  Relaxin signaling pathway
morg04932  Non-alcoholic fatty liver disease
morg04933  AGE-RAGE signaling pathway in diabetic complications
morg04935  Growth hormone synthesis, secretion and action
morg04936  Alcoholic liver disease
morg05014  Amyotrophic lateral sclerosis
morg05020  Prion disease
morg05022  Pathways of neurodegeneration - multiple diseases
morg05132  Salmonella infection
morg05133  Pertussis
morg05135  Yersinia infection
morg05140  Leishmaniasis
morg05142  Chagas disease
morg05145  Toxoplasmosis
morg05152  Tuberculosis
morg05161  Hepatitis B
morg05163  Human cytomegalovirus infection
morg05167  Kaposi sarcoma-associated herpesvirus infection
morg05169  Epstein-Barr virus infection
morg05170  Human immunodeficiency virus 1 infection
morg05171  Coronavirus disease - COVID-19
morg05205  Proteoglycans in cancer
morg05208  Chemical carcinogenesis - reactive oxygen species
morg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
morg05415  Diabetic cardiomyopathy
morg05417  Lipid and atherosclerosis
morg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:morg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121461212 (Mapk12)
   04015 Rap1 signaling pathway
    121461212 (Mapk12)
   04370 VEGF signaling pathway
    121461212 (Mapk12)
   04668 TNF signaling pathway
    121461212 (Mapk12)
   04068 FoxO signaling pathway
    121461212 (Mapk12)
   04071 Sphingolipid signaling pathway
    121461212 (Mapk12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    121461212 (Mapk12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    121461212 (Mapk12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    121461212 (Mapk12)
   04218 Cellular senescence
    121461212 (Mapk12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    121461212 (Mapk12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    121461212 (Mapk12)
   04613 Neutrophil extracellular trap formation
    121461212 (Mapk12)
   04620 Toll-like receptor signaling pathway
    121461212 (Mapk12)
   04621 NOD-like receptor signaling pathway
    121461212 (Mapk12)
   04622 RIG-I-like receptor signaling pathway
    121461212 (Mapk12)
   04625 C-type lectin receptor signaling pathway
    121461212 (Mapk12)
   04660 T cell receptor signaling pathway
    121461212 (Mapk12)
   04658 Th1 and Th2 cell differentiation
    121461212 (Mapk12)
   04659 Th17 cell differentiation
    121461212 (Mapk12)
   04657 IL-17 signaling pathway
    121461212 (Mapk12)
   04664 Fc epsilon RI signaling pathway
    121461212 (Mapk12)
   04670 Leukocyte transendothelial migration
    121461212 (Mapk12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    121461212 (Mapk12)
   04914 Progesterone-mediated oocyte maturation
    121461212 (Mapk12)
   04917 Prolactin signaling pathway
    121461212 (Mapk12)
   04926 Relaxin signaling pathway
    121461212 (Mapk12)
   04935 Growth hormone synthesis, secretion and action
    121461212 (Mapk12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121461212 (Mapk12)
  09156 Nervous system
   04728 Dopaminergic synapse
    121461212 (Mapk12)
   04723 Retrograde endocannabinoid signaling
    121461212 (Mapk12)
   04722 Neurotrophin signaling pathway
    121461212 (Mapk12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    121461212 (Mapk12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    121461212 (Mapk12)
  09159 Environmental adaptation
   04714 Thermogenesis
    121461212 (Mapk12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    121461212 (Mapk12)
   05208 Chemical carcinogenesis - reactive oxygen species
    121461212 (Mapk12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    121461212 (Mapk12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    121461212 (Mapk12)
   05161 Hepatitis B
    121461212 (Mapk12)
   05171 Coronavirus disease - COVID-19
    121461212 (Mapk12)
   05163 Human cytomegalovirus infection
    121461212 (Mapk12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121461212 (Mapk12)
   05169 Epstein-Barr virus infection
    121461212 (Mapk12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    121461212 (Mapk12)
   05135 Yersinia infection
    121461212 (Mapk12)
   05133 Pertussis
    121461212 (Mapk12)
   05152 Tuberculosis
    121461212 (Mapk12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    121461212 (Mapk12)
   05140 Leishmaniasis
    121461212 (Mapk12)
   05142 Chagas disease
    121461212 (Mapk12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    121461212 (Mapk12)
   05020 Prion disease
    121461212 (Mapk12)
   05022 Pathways of neurodegeneration - multiple diseases
    121461212 (Mapk12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    121461212 (Mapk12)
   05418 Fluid shear stress and atherosclerosis
    121461212 (Mapk12)
   05415 Diabetic cardiomyopathy
    121461212 (Mapk12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    121461212 (Mapk12)
   04932 Non-alcoholic fatty liver disease
    121461212 (Mapk12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    121461212 (Mapk12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    121461212 (Mapk12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:morg01001]
    121461212 (Mapk12)
Enzymes [BR:morg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     121461212 (Mapk12)
Protein kinases [BR:morg01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   121461212 (Mapk12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 121461212
NCBI-ProteinID: XP_041528083
LinkDB
Position
Unknown
AA seq 367 aa
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAIDSRTGNKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRVQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGSDHLDQLKEIMK
VTGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLEKMLVLDSEQRV
TAAEALAHPYFESLQDTEDESKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGAR
VPKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctccccgccacccgcccgcaagggcttttaccgccaggaggtgaccaaaacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctctggtgcctatggtgca
gtgtgctctgcaatagacagccgcactggtaacaaggtggccatcaagaagttgtaccgg
cccttccagtcggagctgtttgccaagcgcgcctacagagagctgcgcctcctcaaacac
atgcgccacgagaacgtgattggcctactggatgtgttcactcctgatgagactctggat
gacttcacagacttctacctggtgatgccgttcatgggcactgatctgggcaagctgatg
aagcacgagactctgagtgaagacagagtccagttccttgtgtatcagatgctgaagggg
ctgaagtatatccacgctgctggtgtcatccacagagatttgaagcctggcaacctggct
gtgaatgaagactgtgagctgaagatcctagactttggcctagccagacaggcagacagt
gagatgacgggatatgtggtgacccggtggtaccgggcaccagaggtcatcttgaattgg
atgcgctacacacagacagtggacatctggtctgtcggctgcatcatggcggagatgatt
acagggaagattctgttcaaaggcagtgaccacctggaccagctgaaggagatcatgaag
gtcacagggacaccccctcctgagtttgtacagaagttacagagtgctgaggccaagaac
tacatggaaggccttcctgagctggaaaaaaaggattttgcctctgtcctgaccaacgca
agccctcaggctgtgaaccttctagaaaagatgctggtgctggactcagaacagcgggtg
acggcagctgaggcactggcccatccgtactttgagtccctgcaggataccgaggatgag
tccaaggcccagaaatacgatgactcctttgatgacgtggaccgcacccttgaggagtgg
aagcgtgttacttacaaggaagtgctcagcttcaagcctcccaggcagctaggagccaga
gtcccaaaggagacagctctatga

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