KEGG   Microtus oregoni (creeping vole): 121461353
Entry
121461353         CDS       T08307                                 
Symbol
Igf1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
morg  Microtus oregoni (creeping vole)
Pathway
morg01521  EGFR tyrosine kinase inhibitor resistance
morg01522  Endocrine resistance
morg04010  MAPK signaling pathway
morg04014  Ras signaling pathway
morg04015  Rap1 signaling pathway
morg04066  HIF-1 signaling pathway
morg04068  FoxO signaling pathway
morg04081  Hormone signaling
morg04114  Oocyte meiosis
morg04115  p53 signaling pathway
morg04150  mTOR signaling pathway
morg04151  PI3K-Akt signaling pathway
morg04152  AMPK signaling pathway
morg04211  Longevity regulating pathway
morg04213  Longevity regulating pathway - multiple species
morg04510  Focal adhesion
morg04550  Signaling pathways regulating pluripotency of stem cells
morg04730  Long-term depression
morg04750  Inflammatory mediator regulation of TRP channels
morg04913  Ovarian steroidogenesis
morg04914  Progesterone-mediated oocyte maturation
morg04935  Growth hormone synthesis, secretion and action
morg04960  Aldosterone-regulated sodium reabsorption
morg05200  Pathways in cancer
morg05202  Transcriptional misregulation in cancer
morg05205  Proteoglycans in cancer
morg05214  Glioma
morg05215  Prostate cancer
morg05218  Melanoma
morg05224  Breast cancer
morg05410  Hypertrophic cardiomyopathy
morg05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:morg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121461353 (Igf1)
   04014 Ras signaling pathway
    121461353 (Igf1)
   04015 Rap1 signaling pathway
    121461353 (Igf1)
   04066 HIF-1 signaling pathway
    121461353 (Igf1)
   04068 FoxO signaling pathway
    121461353 (Igf1)
   04151 PI3K-Akt signaling pathway
    121461353 (Igf1)
   04152 AMPK signaling pathway
    121461353 (Igf1)
   04150 mTOR signaling pathway
    121461353 (Igf1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    121461353 (Igf1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    121461353 (Igf1)
   04115 p53 signaling pathway
    121461353 (Igf1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    121461353 (Igf1)
   04550 Signaling pathways regulating pluripotency of stem cells
    121461353 (Igf1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    121461353 (Igf1)
   04914 Progesterone-mediated oocyte maturation
    121461353 (Igf1)
   04935 Growth hormone synthesis, secretion and action
    121461353 (Igf1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    121461353 (Igf1)
  09156 Nervous system
   04730 Long-term depression
    121461353 (Igf1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    121461353 (Igf1)
  09149 Aging
   04211 Longevity regulating pathway
    121461353 (Igf1)
   04213 Longevity regulating pathway - multiple species
    121461353 (Igf1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121461353 (Igf1)
   05202 Transcriptional misregulation in cancer
    121461353 (Igf1)
   05205 Proteoglycans in cancer
    121461353 (Igf1)
  09162 Cancer: specific types
   05214 Glioma
    121461353 (Igf1)
   05218 Melanoma
    121461353 (Igf1)
   05215 Prostate cancer
    121461353 (Igf1)
   05224 Breast cancer
    121461353 (Igf1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    121461353 (Igf1)
   05414 Dilated cardiomyopathy
    121461353 (Igf1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    121461353 (Igf1)
   01522 Endocrine resistance
    121461353 (Igf1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:morg04052]
    121461353 (Igf1)
Cytokines and neuropeptides [BR:morg04052]
 Cytokines
  Growth factors (RTK binding)
   121461353 (Igf1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 121461353
NCBI-ProteinID: XP_041528331
LinkDB
Position
Unknown
AA seq 193 aa
MSASPVSNTHSFKGREKTLLCSSFEKQRLCTSEAMGKVTGLPAQLFKCCFCDFLKIKMHA
MSSSHLFYLALCLLTFTSSATAGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRA
PQTGIVDECCFRSCDLRRLEMYCAPLKPTKSARSIRAQRHTDMPKTQKSQPLSTNKKMKP
QRRRRGSTFEERK
NT seq 582 nt   +upstreamnt  +downstreamnt
atgtctgctagccctgtcagtaacacacattcttttaaggggagagaaaaaacgcttctg
tgctccagttttgaaaagcaaagactttgcacttcagaagcgatgggaaaagtcaccggt
cttcctgctcaattatttaagtgctgcttctgtgatttcttgaagataaagatgcacgcc
atgtcgtcctcccatctcttctacctggccctctgcttgctcaccttcaccagctctgcc
acagctggacctgagaccctctgcggggccgagctggtggacgctcttcagttcgtgtgt
ggaccaaggggcttttacttcaacaagcccacgggctacggctccagcattcggagggct
cctcagacaggcatcgtggatgagtgctgcttccggagctgtgacctgagaaggctggag
atgtactgtgctcccctcaagcctacaaaatcagcccgctctatccgtgcccagcgccac
actgacatgcccaagactcagaagtcccagcccctatccacgaacaagaaaatgaagcca
caaaggagaaggagaggaagtacatttgaagaacgcaagtag

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