Microtus oregoni (creeping vole): 121461903
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Entry
121461903 CDS
T08307
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00230
Purine metabolism
morg00670
One carbon pool by folate
morg01100
Metabolic pathways
morg01523
Antifolate resistance
Module
morg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
121461903 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
121461903 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
121461903 (Gart)
Enzymes [BR:
morg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
121461903 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
121461903 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
121461903 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
RimK
ATP-grasp_5
LUD_dom
Motif
Other DBs
NCBI-GeneID:
121461903
NCBI-ProteinID:
XP_041529196
LinkDB
All DBs
Position
Unknown
AA seq
1004 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSLHVKQVLVAPGNAGTACSGKISNAAVSVNDHAVLAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTCAGVRCFGPTAQAAQLESSKKFAKEFMERHGIP
TAQWRAFTKPEDACSFIMSANFPALVVKASGLAAGKGVIVAKNKEEACKAVREIMQEKSF
GAAGETVVVEEFLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDEGPNTGGMGAYCPTP
QVPKDLLLKIKDTILQRTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGQLSASLPVWLENHTAITVVMASKGYPGAYSKGVEITGFPEA
QALGLQVFHAGTALKDGRVVTSGGRVLTVTAVQENLESARDEARKGLAAIKFEGAVYRKD
IGFRAVAFLQRPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRPGCTVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHGTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLTTTEAVIAGIAGACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
QLERIVEGDVVVGVASSGLHSNGFSLVRKIVARSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPVIRSGRVKALAHITGGGLLENIPRVLPRELGVDLDAGTWRIPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKNQADQILHDIRQRQEEAWVIGSVVACPKDFPRVRVKN
LIETMQVNGSTVSNGFLRSKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVVVISNKAG
VAGLDKAEKAGIPTRVINHKLYKNRVEFDNAVDLVLEEFSVDVVCLAGFMRILSGPFVRK
WDGKMLNIHPSLLPSFKGSNAHEQVLKAGVTVTGCTVHFVAEDVDAGQIVLQEAVPVKRG
DTVATLSERVKVAEHKIFPAALQLVASGAVRPGEDGKVHWVREQ
NT seq
3015 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttcttgtgattggcagtggaggaagggaacatactctggcctggaaa
cttgcacagtctcttcatgtcaaacaagtgttggttgcccctggaaatgcaggcactgcc
tgttctggaaagatctcaaacgctgctgtctccgtcaatgatcacgctgtccttgctcag
ttctgcaaagatgagaagatcgagtttgtggtggttggaccagaggcccctctggctgca
gggattgttggggacctgacctgtgcaggagtacgatgctttggccccacagcacaagca
gctcagttagagtccagtaaaaagtttgccaaagaatttatggagcgacatggaatccca
actgcacagtggagagcattcaccaaacctgaagatgcctgcagctttattatgagcgca
aactttcctgctttggttgtgaaggccagtggccttgcagctgggaaaggggtgattgtt
gcaaagaacaaagaggaggcctgcaaagctgtacgggagatcatgcaggaaaagtctttt
ggagcagctggagaaacggttgttgtggaagagttcctggacggggaagaagtgtcttgt
ctgtgtttcactgatgggaagacagtggccccaatgcctccagcacaggaccataagcga
ttgctggatggagatgagggccccaacacagggggaatgggagcctactgccctacacct
caggttcctaaggatttgttactaaaaattaaagacactattcttcagagaacagtagac
ggcatgcagcaggagggtgtgccttacacaggaattctctatgctggtataatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgatccagaatgccaagta
atcctcccacttcttaaaagtgacctttatgaagtgattcagtccaccttagatggccag
ctgagtgcgtctctgcctgtttggctagaaaaccacactgccataaccgttgtcatggca
agtaaagggtatcctggagcctacagcaagggtgtggagataacagggtttcctgaggcc
caagctttaggactccaggtattccatgcgggcactgctcttaaagatggcagagtggtg
accagcgggggaagagtcctcacggtaacggccgtccaggagaatcttgagtcagcccgt
gacgaagccaggaaaggccttgctgccataaagtttgagggcgcagtttataggaaggac
attggcttccgtgctgtagccttcctccagcggcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgtactgtagaccttggaggctttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctctcctggcgtctggaacagatggtgttgggactaaactg
aagattgcccagctgtgcaataagcatggcaccatcggtcaggatctggtcgcaatgtgt
gtaaacgacatcctcgcacagggagctgagcccctcttcttcctcgattacttttcctgt
ggaaaactcgacctcactacaactgaagctgttatcgctggaattgctggagcctgtaga
caagctggctgtgctctcctaggtggagagaccgcagagatgcccgacatgtaccctcct
ggcgagtatgacctcgctgggtttgctgttggcgctatggagagggatcagaaactccct
cagctagaaaggattgtcgaaggggatgttgtggttggggtagcctcatctggtcttcac
agcaatggctttagccttgtgaggaagattgtggcgaggtcttctctgcagtactcctct
ccagcgcctgatggatgtggcgaccagactttaggggacttgcttctaactccaaccagg
atctacagccattcgctgttgcctgtcatacggtcaggacgtgtcaaagccttggctcac
attactggaggtggattgctggaaaacatccccagagtccttcctcgggagctcggagta
gatttagatgctggcacctggaggatccccaaggtcttttcatggttacagcaggaagga
cagctctctgaagaagaaatggccagaactttcaactgtggggttggagctgccttggtg
gtgtctaagaaccaggcagaccagattctgcatgacattcggcagcgccaggaggaagcc
tgggtaataggcagtgttgtggcatgtccgaaagatttccctcgtgtcagagtcaagaat
ttgattgaaaccatgcaagtaaatgggtcaacggtgtcaaatggcttcctgagaagtaag
aaggccagagtggctgtcttaatatctggaacagggtccaacctccaggctctcatagac
agcactcgggatccaaagagctcctcacacattgttgttgtcatctccaacaaagctggg
gtcgctggcttagacaaagcagaaaaggctggcattcccaccagagtgattaatcataaa
ttatataagaaccgtgttgaatttgacaatgctgttgacctcgtcctagaagagttctct
gtagacgtggtctgtcttgctgggttcatgaggattctctctggcccttttgtcaggaaa
tgggatggtaaaatgctcaacatccacccatccttgctcccttctttcaagggttcaaat
gctcatgagcaagtcctgaaagctggagtcacagttaccgggtgcaccgtacactttgtg
gccgaggatgtagatgccggacagatcgtcctacaagaagctgtccctgtgaagaggggt
gacactgttgccactttgtctgagcgagtcaaagtagcagagcataaaatctttcccgca
gccctccagctggtggccagcggggccgtgcggcctggagaagacggcaaggtccactgg
gtcagggagcagtga
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