Microtus oregoni (creeping vole): 121462522
Help
Entry
121462522 CDS
T08307
Symbol
Setx
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
121462522 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
morg03021
]
121462522 (Setx)
Enzymes [BR:
morg01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
121462522 (Setx)
5.6.2.5 RNA 5'-3' helicase
121462522 (Setx)
Transcription machinery [BR:
morg03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
121462522 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
ResIII
Helicase_RecD
SLFN-g3_helicase
AAA_16
Zn_ribbon_HMPTM
nSTAND3
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
121462522
NCBI-ProteinID:
XP_041530066
LinkDB
All DBs
Position
Unknown
AA seq
2608 aa
AA seq
DB search
MLGLMKQNKREKTRYRMSTCCWCTPGGTSTVDVIKCYASSTGSSEFQTADEDLCYCLECV
AEYHRARDEVPFLHEVLWELETLRLINHFEKSMKAEVEEDDELYIVDNNGEEQLFDCSGQ
DFENKLRVPLFEILKYPYLLLHERVNELCVEALCRMEQTNCSFQVFDKYPGIYLFLVHPN
EMVRRWAILTARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSMLEKGKLILL
PAHMYDTTNYKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDDDSMD
PFWPALHCFMVILDRLGSKVWGQLIDPIEAFQTIINNVSYNREIQNIRKNSIRTKSEPEP
HFDDMVTCSQIVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVH
NSTFLWFIPFVQSLMDLKDLGVAYIVEVIHHLYSEVKDVLNQTDTVCDKVTEFFILILVS
VIELHRNKKCLHLLWVSSQQWVEAVVKCAKLPTTAFARSSEKLPGNIPKGAAIIPPLALH
SVPSSSVQLACVQLIRGLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLSTQETHDL
QMCLKQIIKNIKFKMPQYSTFGELTSTCKTSPSFKEESEQTDRKPKRDFYCLEYCSPTSS
KESEKADSNQVLIKADNTEEEGIKQHYIDLNEDEPLPAELCLKGKSEAPFFGRVQEQVKV
STEKSVKENSSYTLQNNTLRNGLEWECDRGVIISTHSLTNSSMDSLEKVSTSNEDVSVKN
ETVGKNSKPKSKAQKDEICAKLSHVIKKQHRKSTLVNNTISLEENAALSDLENSCSGKYR
RFLKEDTVKHDVSLEPVSDDEHGEQNSQKSSLLKKKQLKSEELDNSDGKKCQTRECHAAA
DLLPVTDRLVKKTSYEGPEKVEVESRDKEIKSTVMTSNMVKGEVPHGNSKPLVTGPQIDL
CNVALIAQTTVIQFPSGSSKSPSQLQRKDDIRCLTANPNSADTCHEQVIVISDSDEDDDE
RSHGIEKHIKQDKVYMEKECPEQHGSVVNSIVEHIKEEETKYPIEFEDSESQVFEFESCS
EVFSVWQDHKVDSKNSLQEEGRSYLTHVADNTNDNLGCGVDSVSEEVVINEAEDIEEHTE
PHSSVSVEGFCKTGGKHKRKQCKRVTTEDAQKSSFSFIAEQSTDDRDLSGSDLRSADIGT
SALSSSVERDSAVSLMSTKLHTHSKPVRKVPASKAIKKTYLDTKRGRSKSSCYISCRTSP
AVVPPKKFRQYPQPSSAPEKLGLRKPPRRAFELSQRSLESTSQLRQHGKTVGVVNIPRKA
KLIQSLKNKKLLTSQEIQFQKLSRGRPHKKRDLDYKNTDTVRIVLGSDVLVPDSDGPDNH
RGSEPPANSNEKQLAKCMPSKPEVAKAISYPQVMDIAGLVNQCESGVSSEGVPTDEDPVD
EDAVKATEPESGSDTDDDNLFLTQHDPLDMDLCSQMENNKPIIVAHKDTIQREDFVSQPQ
LESLNVTKCKYKDCVESTINHGEYCPRHSETKPADDDVFRKPFAVPRPSRPTTTKIFSSS
SASRTANFSKSLESTILQSALKKPNVAQPNLKVTPPSSLVSQKPVAEVKSLCNISHFRTP
GSSIRHSYKPILSETRPMSASRVNIPLPSQPVFDTFIKEVLKWKYQMFLNFDKCGAPASL
CQSISRSVPIQFQDYAEYFNVFLPLIILNTFETVAQEWFNSPNKKNFYHLYLRKFPADYK
KYWEFMIYLEESELAKQLHPKENDLVFLVPESLNREEKDMDENDMQDRNAYYCGYVHKFR
RTSVMNSGKTECSLCIQTQDNLAARLQELTKCLVISSLVTTQRKLKAMSLLSGWNQLARA
VLNPNPMDFCTKDLLTTTSERIINYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPP
GTGKSKTIVGLLYRLLTENQRKGHSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILEFK
EKCKDKKNPMGNCGDINLVRLGPEKSINTEVLKFSLDSQINHRMKKDLPSHIQEMLRRKE
FLDGQLDELSRQRALCRGGREMQRQELDGHIVKVSKERQELASKIKEVKGRPQKTQNTII
LESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILV
GDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEDYVKQNKIGRLPVLQLTVQYRMHPDIC
LFPSNYVYNKNLKTNSATESVRCSSEWPFQPYLVFDVEDGSERRDNDSYINVQEIKLVME
IIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKKGPAEVDTVDAFQGRQKDCI
IVTCVRASSEQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNELIQDAQKRG
AIIKTCDPHYRHDAMKILKLKPVLQRSLTHPPATAPEAPRPQGGLPSNKLDSGLAKTPSA
ASLYHTPSDTVTSKEPKRTPQDRLRDPRLLRRLDAESKGTSLKDPQSVGPHFLDPNFVVG
PSMAIVAPLGSHRSPLQAEPPPAHPAAPSTSKRKYSGSNSGFSHRREPRAFGEEERRGSV
SHHMLRSTDWDRRRLEQEPSSAKKSRFP
NT seq
7827 nt
NT seq
+upstream
nt +downstream
nt
atgctaggactgatgaagcagaacaagagggaaaaaacaaggtacagaatgagcacatgc
tgttggtgtactccaggtggtacttccaccgttgatgtcataaagtgctatgcatcgagc
actggatcaagtgaatttcaaacagctgatgaagacctctgctactgcttggagtgcgtg
gctgagtaccacagagccagagatgaggtgccattcttgcatgaggttttatgggaacta
gaaaccttacgcctcataaatcactttgagaagtctatgaaggcagaagttgaagaagat
gatgaattatatatagtagacaacaatggagaggaacagctatttgactgtagtggccaa
gattttgaaaataagcttcgagttcctctttttgaaatactgaagtacccttacttgctt
ctgcatgagcgtgttaatgaactgtgtgtggaagcactttgtcgaatggaacagaccaat
tgctcctttcaggtgtttgacaaatatccagggatctatttgtttttggttcatcccaat
gaaatggttcggcgatgggctattctgactgcaagaaacttggggaaagtggacagagat
gactattacgacttgcaggaagttttaacttgcctttttaaagtcattgagttggggctt
ttggaaagtccagacatttacacatcttctatgcttgaaaaaggcaaactgatccttctg
cctgcgcacatgtatgatactaccaactacaaaaactattggctaggtatttgcatgttg
ctgactattcttgaagagcaagctatggattcactgttgttgggttcagacaaacaaaat
gattttatgcagtcaatccttcacaccatggagaagcaatcggatgatgacagcatggat
cctttctggccagcattacactgtttcatggtgattctggatcgccttggatcaaaagtg
tggggtcaacttattgaccccattgaagcctttcaaaccattattaacaatgtgagctac
aacagagagatccaaaatatacggaaaaactccataaggaccaagtcagaaccggagcca
cattttgatgatatggtgacgtgcagccagattgtctataactataatcctgaaaagacc
aaaaaggattcagggtggagatcagccatttgtccagattattgtcctaacatgtatgaa
gaaatggaaacgttagccagtgttcttcaatcagatattggtcaagacatgcgtgttcat
aacagcacctttctgtggttcataccttttgttcagtcactcatggatcttaaggatttg
ggtgtagcttacattgtagaagttattcatcatctatactctgaagtcaaagatgtcctc
aaccagacagatactgtgtgtgacaaagtcactgaattttttattctgattttagtgtct
gtgattgaactgcatagaaataaaaagtgcttgcatctgctgtgggtgagttctcagcag
tgggtagaagctgttgtaaagtgtgccaagcttcctaccactgcatttgcacgaagttct
gagaagttgcctggaaatatccctaaaggagcagcaataataccaccattggcattgcat
tcagtgccctctagctctgttcagcttgcttgtgtgcagttgattaggggactcctcaaa
gaaggttatcagcttggtcagcaaacactttgtaagcgcttctgggataaacttaactta
ttccttcgaggaaatttatctctgggttggcagttgtctactcaagaaacccatgacttg
caaatgtgtttaaaacaaataattaaaaacataaaattcaaaatgccccagtatagcact
tttggggaactgacttctacatgtaaaacttctccatcttttaaagaagaaagtgaacaa
acagacaggaagcctaaaagagacttttattgcctggaatattgcagccccacatcttct
aaagaatcagagaaagctgacagcaatcaggtattgattaaagcagataatacagaagag
gagggcatcaagcagcattacattgatttgaatgaagacgagcctcttccagctgagttg
tgcttgaagggaaagagcgaggcccctttttttggacgtgttcaagagcaagttaaagta
agcacagagaagtctgtaaaagaaaactcttcatatacactacagaataatactttaaga
aatggcctagaatgggaatgtgacagaggagtaataatatcaacgcattcattgactaat
tctagcatggattctttggaaaaggtatctacatcaaatgaagatgtctcagtaaagaat
gaaactgttggcaaaaactcaaaaccaaagtctaaagcacagaaggatgagatttgtgca
aagttatcacatgtcataaagaaacaacacaggaaaagtactttggtcaataatactatt
agtctagaggaaaatgcagctttgtctgaccttgagaactcctgttcaggaaaatataga
cggtttctaaaggaagatactgtcaaacatgatgtgtctttagaacctgtttcagatgat
gaacatggagagcaaaattctcaaaagagttcattgttaaaaaagaaacagttaaaaagc
gaggagttagataattctgatgggaaaaagtgtcaaacccgggaatgccatgctgctgct
gatttgttaccagttactgatagactggtgaagaaaacttcatatgagggtcctgaaaag
gttgaagttgaatcaagagataaggaaataaagagtacagtgatgacttctaacatggta
aaaggagaggtgcctcatggcaatagcaagcctttggtaacaggtcctcaaatagacctt
tgtaacgtagctttaatagctcaaaccactgttattcagtttccatcaggttcaagtaaa
agtccatcccagctacaaagaaaagatgatataagatgtttgacagctaacccaaacagt
gctgatacctgccacgagcaagttattgttatttcggattctgatgaagatgatgatgag
agaagtcatggcattgagaaacacatcaaacaggacaaagtatacatggagaaagaatgt
ccagagcagcatgggtcagtagttaatagcattgtggaacatataaaggaagaagaaaca
aagtaccctattgaatttgaagactctgaatctcaggtttttgagtttgaaagttgttct
gaagtgttctcagtttggcaagatcataaagtagacagtaagaactcccttcaagaggaa
ggaagaagctatctaactcatgtagctgataatacaaatgataatttgggttgtggtgta
gactctgtgtctgaagaggttgttataaatgaagcagaggatattgaagagcatacagaa
ccacacagtagtgtttctgttgagggattttgtaaaaccggaggaaaacataagagaaaa
cagtgtaaaagagttacaactgaagatgctcagaaatcttcattttccttcatagctgag
caatcgactgatgacagagatctttctggaagtgatttaagaagtgcagacatagggacg
tcagctctcagttcaagtgttgagagagattctgcagtttcactgatgtctacaaagctt
catactcactctaaacctgtcaggaaagttccagcttctaaggctattaagaaaacctat
ttagacaccaaaagaggtcggagtaagagttcatgttatatcagctgtagaacatctcct
gctgttgtgccaccaaagaaatttcgccagtatccccagccatcttcagcgcctgaaaag
cttggtctaagaaaacctccccggagggcatttgagttgtctcagaggtctttggagtct
acatcccaattacgtcaacatggtaagactgttggagtagttaacatccccagaaaggct
aaattaattcaatccttaaaaaataagaagcttctgacaagccaggaaattcagtttcaa
aaacttagtagaggcagaccacataaaaaacgagaccttgattacaaaaataccgatact
gtgagaatagtgctgggttccgacgtacttgtaccagactctgatgggccagataatcat
agaggaagtgagccacctgccaacagtaatgaaaagcaattagcaaaatgcatgccttct
aaaccagaagtggcaaaagccatttcctatcctcaggtgatggatatagctggtcttgtg
aaccagtgtgagtctggagtgtcaagtgaaggagtaccgacagatgaggaccctgtggat
gaagatgctgtgaaagctacagagccagaatccggtagtgatacagatgatgacaattta
ttcctaacacaacatgatcctctagatatggatctgtgctcacagatggaaaataataaa
ccaattatagtggctcataaagatacaattcagagagaagattttgtaagtcagcctcag
ttagagtctttgaatgtcacaaagtgtaagtacaaagactgtgttgaatccacgataaac
catggtgaatattgcccaagacactctgaaactaaaccagcagatgacgacgtgtttcgt
aaaccctttgctgtacccaggccctcaagacctactactaccaagatatttagctcaagc
agtgcttcacgaactgccaatttttccaagtctttggaaagtaccattcttcagtcagca
ctaaaaaagccaaatgtggcacagcctaatttgaaggtgacaccaccctcttccctggtg
tctcagaagccagtggctgaggtgaaaagtttatgcaatatttctcattttcggactcca
ggcagttccatcagacatagttacaagcctatacttagtgagaccaggcctatgtcagct
tctcgagtgaatattcccttaccatcacagcctgtctttgacaccttcattaaggaggtc
ttaaaatggaaataccaaatgtttttgaactttgataaatgtggcgccccagcaagtctc
tgtcaatctatctcaagatctgtgcccatccaatttcaagattatgcagagtattttaat
gtttttcttcctttgattatattgaatacttttgaaacagtggcacaggaatggttcaac
tctccaaataaaaagaatttctatcatttgtatttacgaaaatttccagccgactataaa
aaatactgggagtttatgatttacctggaggaatctgaactagctaaacagcttcatcca
aaggaaaatgatctggtgtttttggttcctgagagtctaaatagagaggagaaagatatg
gacgagaatgacatgcaagatcgaaatgcctattactgtggttatgttcataagtttcgc
cgtacttcagtcatgaacagtggaaaaactgagtgttccttgtgcatccagacacaagat
aacttggcagccagactacaggaacttacaaaatgtcttgtgatcagttctctagtaacc
acacagaggaaattgaaagccatgtctttgttgagcggttggaaccagttggccagagct
gttctaaatccaaaccccatggacttctgtaccaaagacctattaacgacaacatctgaa
agaattattaactacctaaaagacttcaatgaagatcaaaagaaagccatagaaactgca
tatgcaatggtgaaacactcaccatctgttgccaaaatctgtttgattcatggaccacct
ggaacaggaaaatcaaaaaccattgttggtctcttgtaccgcttattgacagagaaccag
agaaagggccactcagatgaaaacttcaatgccaaaatcaagcaaaaccgagtcctcgtg
tgtgcaccttccaatgcagctgttgatgaacttatgaaaaaaatcatccttgaattcaaa
gaaaaatgtaaagacaagaagaatcctatgggaaattgtggagatataaatttagtacga
ctgggtccagaaaagtctattaatacagaggtcctaaaatttagtttggacagccaaatc
aaccacagaatgaaaaaagatttgccttctcatattcaagaaatgctgagaagaaaagag
tttctagatggtcaactcgatgaactttctcgtcagcgagctctgtgtcgaggtgggcgg
gagatgcagaggcaagaattagatggacacattgtcaaagtttcaaaagaaaggcaggaa
cttgcttcaaaaattaaagaggttaagggacgtccacagaaaacacagaataccatcatc
ttggagtctcacgtcatctgctgcacattgagcacaagtggtggtttgctgcttgagtct
gcttttagagggcaagggggtgtcccctttagttgcgtcattgttgatgaggctgggcag
tcttgtgaagttgaaacacttactccacttatccaccgctgcaacaaacttatcctagta
ggagaccccaaacagctccctcccaccgtcatttctatgaaagcacaggagtatgggtac
gaccagtcaatgatggcacgattctgcaagctgcttgaagattatgtgaaacagaacaag
attggcaggctgccggttttacagcttaccgttcagtataggatgcatccagacatttgt
ctcttcccttctaattatgtttataacaaaaacttgaaaacaaatagtgccactgaatcc
gttcgatgttcgtcagagtggccatttcagccctaccttgtgtttgatgttgaagatggt
tcagaacgacgggataatgactcatatataaatgttcaagaaataaagttggtgatggaa
ataattaaacttattaaagaaaaaagaaaagatatttccttccgaaatattggcataata
acccattacaaggcccagaagactatgattcagaaggatttggagaaagaatttgacaag
aaagggcctgcagaagtggatacagtggatgccttccagggccggcagaaagactgtata
attgttacatgtgtcagggcaagttctgagcaaggctcaattggattcctggcgagtttg
cagagattgaatgtcaccattacacgagccaaatacagcctttttatccttggacatttg
aggactctgatggaaaaccaacattggaatgaactgattcaggatgctcagaagcgtggg
gccattattaagacctgtgacccacactacagacatgatgcaatgaagattctgaaactg
aagcctgtgctgcagaggagtctgacccatcctccagccactgccccagaagcacccaga
cctcagggtggcttgcccagcaacaagctagacagtggacttgccaagacaccttctgct
gcttctctgtaccacacaccctctgacactgtcacttcaaaggaacctaaaaggacacct
caagaccgacttcgagatccacgactacttaggagattggatgctgaatccaagggaaca
tccctgaaggatccacagtctgtgggcccccattttctggacccgaattttgttgtggga
ccatccatggctatcgttgctcctctgggtagccacaggtcacctctacaggctgagcca
ccacctgctcaccctgctgctccttccacaagtaagaggaagtacagtggctcgaactct
gggttcagtcacagaagagagcctagggcctttggtgaagaagaaaggcgtggctctgtg
agtcatcacatgctgaggagtactgactgggacaggaggaggctggagcaggagcccagc
agtgccaagaagagccggtttccatag
DBGET
integrated database retrieval system
