Microtus oregoni (creeping vole): 121466173
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Entry
121466173 CDS
T08307
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00270
Cysteine and methionine metabolism
morg00480
Glutathione metabolism
morg01100
Metabolic pathways
morg01240
Biosynthesis of cofactors
morg04216
Ferroptosis
Module
morg_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
121466173 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
121466173 (Gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
121466173 (Gclc)
Enzymes [BR:
morg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
121466173 (Gclc)
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Paralog
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
121466173
NCBI-ProteinID:
XP_041535728
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All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENRKVQLVLSGEDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSVLGENQALCTITSFPRLGCPGFTLPEYKPNPEEEGASKSLFFPDEAI
NKHPRFGTLTRNIRHRRGEKVVINVPIFKDKNTPSPFVETFPEDEEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNRFRISKSRYDSIDSYLSKCGEKYNDIDLTIDQEIYEQLLR
EGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRDAVL
QGMFYFRKDICKGGNAVVDGCSKAQTSSEPAAEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSIITDEINYS
LVLKCNQIANELCECPELLGSGFRKTKYSGGKSESSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacggcatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtactcaagtggggtgacgaggtggaatacatgttggtgtcctttgatcat
gaaaatagaaaagtccagcttgtgctgtctggagaagatgttcttgaaactctacaggag
aagggggaaaggacaaaccccaaccacccaaccctctggagaccggagtatggaagttac
atgatcgaagggacacctggacagccctatggaggaaccatgtccgagttcaacacagtg
gaggacaacatgaggaaacgccggaaggaggccacttctgtgctaggggaaaaccaggct
ctttgcacgataacttctttccccagactaggctgccctggattcacactgcctgaatac
aaacccaacccagaggaagaaggcgcatccaagtctctcttctttccagatgaagccata
aacaaacacccccgctttggtaccctaacaagaaacatccggcataggagaggagaaaag
gtcgttatcaacgtgccaatatttaaagacaagaacacaccatctccatttgtagaaaca
tttcctgaagatgaggaggcagcaaaggcttctaagccagaccatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtgacattccaagcctgcagcatatct
gaagccagatacctttatgatcagctggccactatctgcccaattgttatggctttgagt
gctgcgtctccattttaccgaggctacgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaacacgggaggagagaggcctggagcccctgaagaacaat
cgctttaggattagtaaatctcggtatgattccatagatagctacctatctaagtgtggg
gagaaatacaatgacattgacctgaccatcgatcaagagatctatgagcagctcctgcgg
gaaggccttgatcatcttttggcacagcatgttgctcatctctttattagagacccactc
accctttttgaagagaaaatacacctggatgatgccaacgagtctgaccattttgagaat
attcaatccacaaactggcagacaatgagatttaagcctcctcctccaaactcagatatt
ggatggagagtagagttcagacccatggaggtgcagttaacagactttgagaactcggcc
tatgtggtgtttgtggttctgctcaccagggtgatcctctcatacaaactggatttcctc
atcccactgtccaaggttgatgaaaacatgaaaatggcacagaagcgggatgctgtcttg
caggggatgttctatttcaggaaagacatttgcaaaggtggcaatgctgttgtggatggg
tgtagcaaggcccagaccagctctgagccagcagcagaggagtacaccctcatgagcata
gacaccatcatcaacgggaaggaaggggtgtttcctggactcatccccattctgaactcc
tatcttgaaaacatggaagtagatgtggacaccagatgcagtattctgaactacctaaag
ctaattaagaagagagcgtctggagaactaatgacagttgccagatggatgagagagttc
atcgccaaccaccctgactacaagcaagacagtataataacggatgagataaattatagc
ctcgttttgaaatgtaaccaaattgcaaatgaattatgtgaatgtccagagttacttgga
tcaggatttagaaaaacaaagtacagtggaggcaaaagtgagtcttcaaactag
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