Candidatus Methylomirabilis oxygeniifera: DAMO_1341
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Entry
DAMO_1341 CDS
T02155
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
mox
Candidatus Methylomirabilis oxygeniifera
Pathway
mox00290
Valine, leucine and isoleucine biosynthesis
mox00620
Pyruvate metabolism
mox01100
Metabolic pathways
mox01110
Biosynthesis of secondary metabolites
mox01210
2-Oxocarboxylic acid metabolism
mox01230
Biosynthesis of amino acids
Module
mox_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mox00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DAMO_1341 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DAMO_1341 (leuA)
Enzymes [BR:
mox01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DAMO_1341 (leuA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
DUF2564
Motif
Other DBs
NCBI-ProteinID:
CBE68401
UniProt:
D5MF72
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All DBs
Position
1138690..1140237
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AA seq
515 aa
AA seq
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MSKRILIFDTTLRDGEQAPGCSMNTREKLEMARQLARLKVDVIEAGFAIASEDDFEAVKT
ISQNLKGGPIIASLCRTRDLDIDRAWEALQYADRARIHIFIATSEIHITYKLKSTQEEVL
QAAVTAVKHARRYTDDVEFSPEDAHRSEQDFLCKVVEEVIRAGATTINIPDTVGYGVPWE
FGARIKDLFDRVPNIDKAVISCHCHNDLGLAVANSLEAVRNGAGQVECTINGIGERAGNA
SLEEIVMALRTRKDLLDFETGINTEEIYRSSRLLTSIIGVPVQPNKAIVGANAFAHEAGV
HQHGMLQKPLTYEIMTPESVGVPRSRLVLGKHSGRHAFKKRLDELGVMLPEEAVNRAFIR
FKVVADKKKEVFDDDLLAIVEEEALAAGETYILDHLQFTSGTNLIPTATVRLKRENETLQ
ESGWGDGPVDAAYKAIDQITKVQGRLADYSIRAITGGKDALGEVVLKLEVNGHTVIGKGS
STDVIEASVRAYLNAINKIIGAERPPKDTAAPRGL
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atgagcaagcggattctgatcttcgacaccacgctgagagacggcgagcaggcgccgggt
tgcagcatgaatacccgggagaagctggagatggccaggcaactggcgcgtctgaaggtc
gacgtgatcgaggccggcttcgccatcgcttcggaagacgactttgaagcggtcaagacg
atctcccagaacctgaagggcgggccgatcattgccagcctctgccggactcgtgacctc
gacatcgaccgcgcctgggaggcgctgcaatatgccgatcgcgcaaggatccacatcttc
atcgcaacctcagagattcacatcacctacaagctgaaatcgacccaggaagaggtcttg
caggctgccgtgacagcggtgaaacatgccaggcgttataccgacgatgtcgagttttct
cccgaggatgcccatcggagcgagcaggattttctctgcaaggttgttgaggaggtgatc
agggcgggcgccaccacgatcaacattcccgatacggtcggctatggcgtcccatgggaa
ttcggggcgaggatcaaggacctattcgaccgcgtgcccaacatcgacaaagcggtcata
agctgccactgtcataacgatctcgggttggcggtggcgaattcgctggaggcggtgcga
aacggagccggacaggtcgaatgcaccattaacggaatcggtgagcgcgccggaaacgcg
tcgctcgaagagatcgtcatggcgcttcggacgcgaaaagacctgctcgactttgagacc
ggtatcaacacagaggagatctatcggtcgagcaggctgctcaccagcatcatcggggtc
cccgtccagccgaacaaggccattgtcggcgccaatgccttcgcacacgaggccggcgtg
caccaacacggcatgctgcagaagccgctgacctacgagatcatgaccccggagtcggtg
ggagttccccgaagtcgactggtgcttggcaaacattccgggcggcatgcgtttaagaag
cggctggatgagttgggcgtcatgttgccggaagaggccgtgaaccgggcctttatccgt
tttaaggtcgtggccgataagaagaaagaggtgttcgacgacgacctgttggccatcgtc
gaagaggaggcactggccgccggcgagacctacatccttgaccatctgcagtttaccagc
ggcacaaatctcatcccgactgccaccgtacggctcaagcgcgagaacgagacgctccag
gagtctggctggggtgacggtccggtggacgcagcatacaaagcgatcgaccagattacg
aaggtccaaggacggctggccgactattcgatcagagccatcacaggcggcaaggacgcg
ctaggcgaggtagtcctgaagctggaggtcaatggtcacaccgtgatcggcaaaggcagt
tcgaccgatgtcatcgaggccagcgtcagggcgtacttaaacgcgatcaacaagatcatc
ggcgccgagcggccgccaaaggatacggctgcgccgagaggactgtga
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