Mus pahari (shrew mouse): 110315110
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Entry
110315110 CDS
T05929
Symbol
Nos3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah00220
Arginine biosynthesis
mpah00330
Arginine and proline metabolism
mpah01100
Metabolic pathways
mpah04020
Calcium signaling pathway
mpah04022
cGMP-PKG signaling pathway
mpah04066
HIF-1 signaling pathway
mpah04071
Sphingolipid signaling pathway
mpah04151
PI3K-Akt signaling pathway
mpah04370
VEGF signaling pathway
mpah04371
Apelin signaling pathway
mpah04611
Platelet activation
mpah04915
Estrogen signaling pathway
mpah04921
Oxytocin signaling pathway
mpah04926
Relaxin signaling pathway
mpah04931
Insulin resistance
mpah04933
AGE-RAGE signaling pathway in diabetic complications
mpah05415
Diabetic cardiomyopathy
mpah05417
Lipid and atherosclerosis
mpah05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
110315110 (Nos3)
00330 Arginine and proline metabolism
110315110 (Nos3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
110315110 (Nos3)
04371 Apelin signaling pathway
110315110 (Nos3)
04066 HIF-1 signaling pathway
110315110 (Nos3)
04020 Calcium signaling pathway
110315110 (Nos3)
04071 Sphingolipid signaling pathway
110315110 (Nos3)
04022 cGMP-PKG signaling pathway
110315110 (Nos3)
04151 PI3K-Akt signaling pathway
110315110 (Nos3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110315110 (Nos3)
09152 Endocrine system
04915 Estrogen signaling pathway
110315110 (Nos3)
04921 Oxytocin signaling pathway
110315110 (Nos3)
04926 Relaxin signaling pathway
110315110 (Nos3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110315110 (Nos3)
05418 Fluid shear stress and atherosclerosis
110315110 (Nos3)
05415 Diabetic cardiomyopathy
110315110 (Nos3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
110315110 (Nos3)
04933 AGE-RAGE signaling pathway in diabetic complications
110315110 (Nos3)
Enzymes [BR:
mpah01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
110315110 (Nos3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
110315110
NCBI-ProteinID:
XP_021044913
Ensembl:
MGP_PahariEiJ_G0021779
LinkDB
All DBs
Position
2
AA seq
1202 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSQAPAPPSPTRPAPAHSPPLTR
PPDGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPTQGPSPTE
QLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF
RIWNSQLIRYAGYRQQDGSVRGDPANVEITELCIQHGWSPGNGRFDVLPLLLQAPDEPPE
LFTLPPEMVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSE
IGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK
GSAAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAAQ
DIFSPKRSWKRQRYRLSTQAESLQLLPGLTHVHRRKMFQATILSVENLQSSKSTRATILV
RLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSAEPVAVEQLEKGSPGGPP
PGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYE
EWKWFSCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTIAVLA
YRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPF
RGFWQDRLHDIEIKGLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDP
GSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGGMELDE
AGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPGPETP
GS
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcctgggccaccctgtggcctagggctcggg
ctgggcttagggctgtgcggcaagcagggcccagcctctccggcaccggagcctagccag
gcaccagcacccccgtccccaacccgaccagcaccagcccacagccccccgctaacccgg
cccccagacggacccaggtttcctcgcgtgaagaactgggaagtgggcagcatcacctac
gacaccctcagtgcccaggctcagcaggatgggccctgtaccccaagacgctgcttggga
tccctggtgtttccaagaaagttacagagccggcccacccagggcccctcacccactgag
cagctattgggtcaagcccgggacttcatcaatcagtactataactccatcaaaaggagt
ggctcccaggctcatgaacagcggcttcaggaagtggaagctgaggtggcagccacaggc
acctaccagctccgggagagcgagctggtgtttggggccaagcaggcctggcgcaatgct
ccccgctgcgtgggccggatccagtggggaaagctgcaggtatttgatgctcgggactgc
aggactgcacaggaaatgttcacctacatctgtaaccacattaagtatgcaacaaataga
ggcaatcttcgctcagccatcacagtgttcccacagcgctgccctggccggggagacttc
aggatctggaacagccagctgatacgttatgcgggctataggcagcaggatggctccgtg
cgaggggaccctgccaacgtggagatcactgagctctgtatccaacatggctggagccca
ggaaatggccgctttgatgtgctgcccctgttactccaggctcctgatgagcccccagaa
ctcttcactctgcccccagagatggtcctcgaggtgcctctggagcaccccacgcttgag
tggttcgccgcccttggcctgcgctggtatgccctcccagctgtgtccaacatgctgcta
gaaatcgggggcctggagtttcctgctgcccctttcagcggctggtacatgagttcggag
attggcatgagggacctgtgtgaccctcaccgctacaacatactcgaggatgtggctgtc
tgcatggatctagacaccaggacaacctcgtccctgtggaaagacaaggcagcggtggaa
attaatgtggctgtactgcacagttaccagctggccaaagtgaccatagtggaccaccac
gccgccacagcctccttcatgaagcacctggaaaatgagcagaaggccagaggaggctgc
cctgccgactgggcctggattgtgccccccatctcaggcagcctaactcctgttttccat
caagagatggtcaactacttcctgtcccctgccttccgctaccagccagacccctggaag
ggaagtgcagcaaagggggcaggcatcaccaggaagaagacctttaaggaagtagccaat
gcagtgaagatctctgcctcactcatgggcacggtgatggcgaagcgtgtgaaggcgacc
attctgtatggctctgagactggccgggcccagagctacgcacagcagctgggaaggctc
ttccggaaggcgtttgatccccgggtcctgtgcatggatgagtatgatgtggtatcccta
gagcatgaggcactggtgttggtggtgaccagcacatttggcaatggggatcccccggag
aatggagagagctttgcagcagcactcatggaaatgtcaggcccgtacaacagctcccct
aggcctgagcagcacaagagctacaaaatccgattcaacagcgtctcctgctcagaccca
ctggtatcctcttggcggcgcaagaggaaggagtctagcaacacagacagtgcaggagcc
ctgggcaccctcaggttctgtgtgtttgggttgggctcccgagcatacccgcacttctgt
gccttcgctcgagcggtggacacaaggctggaggagctgggaggggagcgactactgcag
ctgggccaaggtgatgagctctgtggccaggaggaggctttccgaggctgggcccaggcc
gctttccaggctgcctgtgaaaccttctgtgtgggagaagatgccaaagctgctgcccaa
gatatcttcagccccaaacgcagctggaagcgccagaggtaccggctgagtacccaggct
gagagcctgcagttactaccaggactgactcatgtgcacaggcgaaagatgttccaggct
acaatcctctctgtggaaaacctacagagcagcaaatccacccgagccacaatcctggtg
cgtctagacaccggtggccaggagggactgcagtaccagccaggggaccacataggtgtg
tgcccacccaaccgtcctggcctagtggaggcgctgctgagccgagtggaggaccctccg
ccatccgcagaacctgtggccgtggagcagctggagaaaggcagccctggtggccctccc
cccggctgggtacgggacccccggctacccccatgtacgctgcggcaggctctcacctac
ttcctggacatcacctccccacccagtcctcgcctccttcgactgctcagcaccctggca
gaggagtccagcgaacagcaggagctagaggctctcagccaggacccccggcgctacgaa
gagtggaagtggttcagctgccccacactgctagaggtgctggaacaatttccttcagtg
gcactgcctgccccgctgatcctcacccagctgcccctgctccagccccggtactactct
gtcagttcagcacccagcgcccacccgggagagatccacctcaccatagctgtgctggca
tacagaacccaggatgggctgggccctctgcactacggcgtctgctccacatggatgagc
cagctcaaggcgggagacccagtgccctgcttcatcaggggggctccctccttccggctg
ccacctgatcctaacttgccctgcatcctggtgggcccggggactggcattgcacccttc
aggggattctggcaagacagactacatgacattgagatcaaagggctacaacctgccccc
atgactttggtgtttggctgccgatgctcccagctggaccatctttaccgggacgaggta
ttggacgcccagcagcgtggggtgtttggacaagtcctcaccgccttttccagggatcct
ggcagccccaagacctacgtgcaagacctcctgaggacagagctggccgcggaggttcac
cgtgtgctgtgcctcgagcaaggacatatgtttgtctgcggcgatgtcactatggcaacc
agcgtcctgcaaaccgtgcagcgaattctagcaacagagggcggcatggagctggatgaa
gccggtgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaggacattttcgga
ctcacgttgcgcacccaggaggtgacaagccgcatacgcacccagagcttttctttgcag
gagcgacagctgaggggcgcagtgccctggtcctttgacccacctggcccagaaacgcct
ggttcctga
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integrated database retrieval system
