KEGG   Mus pahari (shrew mouse): 110316341
Entry
110316341         CDS       T05929                                 
Symbol
Cacna2d4
Name
(RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-4 isoform X1
  KO
K04861  voltage-dependent calcium channel alpha-2/delta-4
Organism
mpah  Mus pahari (shrew mouse)
Pathway
mpah04010  MAPK signaling pathway
mpah04260  Cardiac muscle contraction
mpah04261  Adrenergic signaling in cardiomyocytes
mpah04921  Oxytocin signaling pathway
mpah05410  Hypertrophic cardiomyopathy
mpah05412  Arrhythmogenic right ventricular cardiomyopathy
mpah05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mpah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110316341 (Cacna2d4)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    110316341 (Cacna2d4)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    110316341 (Cacna2d4)
   04261 Adrenergic signaling in cardiomyocytes
    110316341 (Cacna2d4)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    110316341 (Cacna2d4)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    110316341 (Cacna2d4)
   05414 Dilated cardiomyopathy
    110316341 (Cacna2d4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mpah04040]
    110316341 (Cacna2d4)
Ion channels [BR:mpah04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   110316341 (Cacna2d4)
SSDB
Motif
Pfam: VWA_N VGCC_alpha2 VWA_3 VWA VWA_2 dCache_1 MCP-like_PDC_1 VWA_CoxE
Other DBs
NCBI-GeneID: 110316341
NCBI-ProteinID: XP_021046222
Ensembl: MGP_PahariEiJ_G0022545
LinkDB
Position
2:134760399..134875436
AA seq 1116 aa
MARCPTLSSSHNQDHSGRWTAAWTFLGKMPIILWLLLSDTSLPTVRGQTTVPLETVKLWA
DTFGRNLYNTVTRYSGSLLLQKKYKDAEPSLKIKEVDGLELVKKFSEDMETMLRRKVEAV
ESLVEAAEEADLNHEFNASLVFNYYNSVLINEKDDKGNYVELGAEFLLESDAHFSNLRVN
VSMSSVQLPTNVYNKDPDILNGVYMSEALNPVFVENFQRDPTLTWQYFGSSTGFFRIYPG
IKWMPDENGVIAFDCRNRGWYIQAATSPKDIVILVDMSGSMKGLRMAIAKHTITTILDTL
GENDFVNIIAYNDYVHYIEPCFKGILVQADRDNREHFKQLVDELMVKGVGVVSQALIEAF
EILKQFQESKQGSLCNQAIMLITDGAVEDYEPVFETYNWPDRKVRVFTYLIGREVTFADR
MKWIACNNKGYYTQISTLADAQENVMEYLHVLSRPMVINHDHDIIWTEAYMDSRLFTSEA
QSLMLLTTVAMPVFSKKNETRSHGILLGVVGSDVTLRELMKLAPRYKLGVHGYAFLNTNN
GYILSHPDLRPLYREGKKLRPKPNYNSVDLSEVEWEDRAEILRTAMINGETGSHSMDVKV
PLDKGKRVLFLTNDYFFTDISDTPFSLGVVLTRGHGEYILLGNTSVEEGLHDLLHPDLTL
ASDWIYCITDIDPDHRKLSQLEAVVRFLTGVDPDLECDEELLREVLFDAVVTAPMEAYWT
ALALNISEESEPGVDVAFLGTRAGLLRRSLFVGSEKLSDRTFLTPEDEASIFTMDHFPLW
YRQASEQPPGSFVFNLRWAEGPDSPGKPVAVRASTAITVTVDGKTAIAAAVGIQMHTDYL
QRQFWAAMQQCNTVEGPCPKTCEDTDLDCFVIDNNGFILISERPQEMGRLLGEVDSALMK
QLLSMGVFSRVTMYDYQAMCKPPDHHHSAAESLFSPLSAFSMVARWLLHECLLFLLEWSA
WGSWQDKGSEAKAVFHHSHKHKKQDLLHPCDTEYPVFVHQTAIQEANGIIECGGCQKTFV
MQQIPRSNLLLLATDCTCDCGVHSPILQEATEVKYNASVKCDRMRSQKPRRRPGSCHAFH
AEENAQDCGGASATLPSSPLLLLSLGAWLLLPQLLC
NT seq 3351 nt   +upstreamnt  +downstreamnt
atggcaagatgccccacgttgtcctccagccacaaccaagaccacagtggacggtggaca
gcagcatggacctttctggggaagatgccaatcatcctgtggctgctgctgtcggacacc
tccctgcctactgtgaggggccagaccacagttcctctggaaacagtgaagctgtgggcc
gataccttcggcaggaatctgtacaacacagtgaccagatattcaggctctctcctgctg
cagaagaagtacaaggatgcagaacctagtctgaagatcaaagaggtggatggcttggag
ctggtgaagaagttctcagaggacatggagaccatgctgcggaggaaagtcgaggctgtt
gagagcctggtggaggccgctgaggaggctgacctgaatcatgagttcaatgcatctctg
gtgtttaactactacaactcggtactaatcaatgagaaggatgacaagggcaactacgtg
gagctgggagctgagtttcttctcgagtccgacgcgcacttcagcaacctgagggtgaat
gtctccatgagcagcgttcaactacccactaatgtgtacaacaaagacccagacatttta
aatggcgtctatatgtccgaagccttgaaccccgtgtttgtggagaactttcagagagac
cctacattaacatggcagtatttcggcagctcaactgggttcttcaggatctatccagga
ataaagtggatgcctgatgaaaatggagtcattgccttcgactgcagaaaccgtggctgg
tacatacaagctgccacgtctcccaaagacatcgtaattctggtggacatgagcggcagc
atgaaggggctgaggatggcgatcgccaagcacaccattaccaccatattggacaccctg
ggagagaatgacttcgtgaacatcatcgcgtacaatgactatgtccactacatcgagccc
tgcttcaaaggcatccttgtccaagcagatagagacaaccgggagcatttcaaacagttg
gtggatgagctgatggtcaaaggtgtgggtgtcgtgagtcaagctctgattgaagctttc
gagatcctgaaacagttccaagagtccaaacaaggaagtctctgcaaccaggccatcatg
ctgatcaccgatggggctgtggaagactacgagcccgtgtttgagacctataactggcca
gaccgaaaggtccgagttttcacttaccttattggaagagaagtgacatttgctgaccgc
atgaagtggattgcctgcaacaataaaggctactacacccagatctccacactggcggat
gcgcaggagaacgtgatggagtacctgcatgtgcttagccgtcccatggtcatcaaccac
gaccacgacatcatctggacagaggcttacatggacagccggctcttcacctcagaggcg
cagagcctgatgctcctcaccacagtggccatgccagtcttcagcaaaaagaatgaaaca
agatcccatggcattctcctgggtgtagtgggctctgacgtgaccctaagagagctcatg
aagctggcaccccgatataagcttggggtgcatggatatgccttcctgaacactaacaat
ggctacatcctctctcatcctgacctccgacctttgtacagagaaggcaagaagctgaga
cccaaacccaactacaacagtgtggacctctcagaagtagagtgggaggaccgagctgaa
atcctgaggaccgccatgatcaatggggaaacggggtctcactccatggacgtgaaggtg
ccactggacaaagggaaacgagttctattcctgaccaatgactacttcttcacagacatc
agtgacacacctttcagcctgggagtggtgctcaccagaggtcatggcgaatacatcctc
ctggggaacacatctgtggaagaaggcctgcatgacttgcttcatccggatctgaccctg
gccagtgactggatctactgcatcacagatatcgacccggaccaccggaaactcagccaa
ctggaagctgtggtccgtttcctgacaggggtggatccagacctggagtgtgacgaggaa
ctgctgcgggaggtgctgtttgacgcagtggtgactgcccccatggaagcctattggaca
gcactggcactcaatatctctgaagagtcagagcccggcgtggatgtggccttcctgggg
acccgggctggccttctaagaagaagcttgttcgtaggctccgagaaactctctgacagg
acgttcctgacccctgaagatgaagccagtatttttaccatggaccacttcccgctgtgg
tatcggcaggcctctgagcagccccctggcagctttgtcttcaatctccgctgggcagag
ggaccagatagcccaggcaagccagtggccgtaagggccagcacagccataaccgtgaca
gtggatgggaagacggccattgcagcagccgtgggcatccagatgcacacagactacctc
cagcgccagttctgggcagccatgcagcagtgcaacacagtagaggggccatgcccgaag
acctgcgaggacactgatctcgactgcttcgtcatagacaacaatggcttcatcctgatc
tcagagagaccccaagagatgggaagacttctgggggaagtggacagtgctctcatgaag
caacttctcagcatgggggtgttcagccgtgtgaccatgtatgactaccaggccatgtgc
aagcccccggatcatcaccacagtgcagccgaatccctgttcagtcctctctctgccttc
tcgatggtggccaggtggctactgcacgaatgtctcctgttcctgttagagtggagtgcc
tggggatcttggcaggacaaagggtcagaggccaaagctgtcttccatcactcccacaag
cacaagaagcaggacctgctgcacccctgtgacacagagtacccagtgttcgtgcatcag
acggccatccaggaagccaacggcatcatcgagtgtgggggctgccagaagacattcgtg
atgcaacagattcccagaagcaacctgctcctgctcgcgacagactgcacctgtgactgc
ggcgtccactctcccatcctccaggaggccacagaagtcaaatataatgcctctgtcaag
tgtgacaggatgcgctcccagaagccccggagacgaccaggctcctgccatgccttccat
gcagaggagaatgcccaggactgtggcggtgcttcggctactctgccttcatcccctctg
ctcctgctatccctgggggcctggctgcttctgccccagcttctgtgttga

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