Mus pahari (shrew mouse): 110320362
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Entry
110320362 CDS
T05929
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah00562
Inositol phosphate metabolism
mpah01100
Metabolic pathways
mpah04014
Ras signaling pathway
mpah04015
Rap1 signaling pathway
mpah04020
Calcium signaling pathway
mpah04024
cAMP signaling pathway
mpah04070
Phosphatidylinositol signaling system
mpah04919
Thyroid hormone signaling pathway
mpah04933
AGE-RAGE signaling pathway in diabetic complications
mpah05205
Proteoglycans in cancer
Module
mpah_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
110320362 (Plce1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
110320362 (Plce1)
04015 Rap1 signaling pathway
110320362 (Plce1)
04020 Calcium signaling pathway
110320362 (Plce1)
04070 Phosphatidylinositol signaling system
110320362 (Plce1)
04024 cAMP signaling pathway
110320362 (Plce1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
110320362 (Plce1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
110320362 (Plce1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
110320362 (Plce1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mpah04131
]
110320362 (Plce1)
Enzymes [BR:
mpah01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
110320362 (Plce1)
Membrane trafficking [BR:
mpah04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
110320362 (Plce1)
Endocytosis
Macropinocytosis
Phospholipase C
110320362 (Plce1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
UNC80_C
GDPD
Motif
Other DBs
NCBI-GeneID:
110320362
NCBI-ProteinID:
XP_021051991
Ensembl:
MGP_PahariEiJ_G0014420
LinkDB
All DBs
Position
1:149865113..150165421
Genome browser
AA seq
2297 aa
AA seq
DB search
MTSEEMAASVLIPVTQRKVASAQAVAEERSEKVSDARIPQARAGRQGALIPPTISQWNKR
KEESSRSDLSKVFSIARGELISDENHNEEGWEETAPDSTVNHAINCSSLVQSHQHQLPQN
QLCEARDSVPEEDPSMQPGIPYPLERKVLPGIQLEMEDSPMDVSPSGSQPGIMESSGPHS
DGHTAVFHFHYEADRTMPDAFHALSENLILDDCANCVTLPGGQQNKNCMAYTCKLVELTR
TCGSKNGQLKCEHCTSLRDEYLCFENSCPKADEVCSGGGFCEDGFAQGPAAKTFLSPLED
FSGNCEDVDDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGRIGPAAWNY
VDQKKAGLLWPCGNVMGPLSAMDIRQSGSQRLTEAQWCLIYSAVRRGEETEETVGSLRHC
ATQLPNSETAHGSLGDGPCLKQCVRDTECEYRATLQRTSIAQYITGSLLEATTSLGARSG
LLSPFGGSTGRIMLKERQPGTSMANSNPVPSSSAGISKELIDLQPLIQFPEEVASILTEQ
EQNIYRRVLPMDYLCFLTRDLSSPECQRSLPRLKASISESILTSQSGERNALEDLVMRFN
EVSSWVTWLVLTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQF
MDQSDIETMRSLKDAMAQHESSVEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASG
LLKLCPRYSSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKELTVNSIFQIIRSCSRSLE
MEEEDSASEGSGSRKNSLKDKARWQFIIGDLLDSENDIFEKSKECDPHGSEESQKAFDHG
TELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWMKPPTASPA
GARPKLGVLSNTAEPGKFPSPGNAGVSGLAEGILDLFSVKAVYMGHPGIDIHTVCVQNKL
SSMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAEMLFSGLLELTTAVRKIRKFPDQRQQW
LRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGMSAKNAEKPNMQRNNTLGIS
TTKKKKKMLMRGESGEVTDDEMATRKAKIYRECRSRSGSDPQDVNEQEELEANVITNPPN
TLHSRRAYSLTTAGSPNLATGMSSPISAWSSSSWHGRIRGGMKGFQSFMVSDSNMSFVEF
VELFKSFSIRSRKDLKDIFDIYSVPCNRSASESAPLYTNLTIEENTSDLQPDLDLLTRNV
SDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVNCQG
EHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNFASKNDESRENKKELQLPL
SYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDGDDGMPIIYHGHTLTT
KIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKSVFGEKLVAKFLFETD
FSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAFTGGNANPPPAS
NEEEEDEEDEYDYDYESLSDADVLTASPVPNSQEDNILEDRPENKLCADKLQFEYNEEGP
KRIKKADNSSGNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLN
SSGSSRGKERKSRKSIFGNNPGRMSPGETAPFNRTSGKGSCEGMRQTWEESSPLSPSTSL
SAIIRTPKCYHISSLNENAAKRLCRRCSQKLIQHTACQLLRTYPAATRIDSSNPNPIIFW
LHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKSCPMYQKFSPLERDLDT
LDPAIYSLTIISGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFL
FRVHFEDLVFLRFAVVENNSSAITAQRIIPLRALKRGYRHLQLRNLHNEILEISSLFINS
RRMEENPSGSTMPASLMFNTEERKCSQTHKVTVHGVPGPEPFAVFTINEGTKAKQLLQQV
LEVGQGTKHTATDYFLMEEKHFISKEKNECRKQPFQRAVGPEEDIVQILNSWFPEEGYVG
RIVLKPQQETLEEKSIVYDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVI
QQTLCKAKYSYSILNNPNPCDYVLLEEVMKDAPNKKSSTPKSSQRILLDQECVFQAQSKW
KGAGKFILKLKEQVQASREDKRRGISFANELKKLTKSTKQSRGLTSPPQFVASESVQSKE
EKPVGALAAGDTVGYQQ
NT seq
6894 nt
NT seq
+upstream
nt +downstream
nt
atgacgtccgaagaaatggccgcttccgtcctcatccctgtgactcaaaggaaagtggct
tctgcccaggcagtggcagaagagaggagtgaaaaggtctcagatgcccggattcctcag
gcacgtgctggcaggcagggtgcgctcatccctcctaccatctcacagtggaacaaacgt
aaggaagagtcttctagaagtgatttgtccaaggtcttctcaatagcgaggggggaacta
atcagcgatgagaatcacaacgaagagggctgggaggaaaccgcaccggactccacggta
aaccatgcgattaactgcagcagcttagtgcaaagccaccagcaccagcttccccagaac
cagctttgtgaagcccgtgactctgtcccagaagaagacccgagtatgcagcctggaatt
ccttacccactggaaaggaaggtgcttcctggaattcaactggagatggaggactctccc
atggacgtgagcccttcgggaagtcagcctgggatcatggagtccagcggacctcactct
gacggccacacggcggtatttcacttccattatgaagctgacaggacaatgccggatgct
tttcatgccctgtcagaaaacttgattttggatgactgtgcaaattgtgttactcttcct
ggggggcagcaaaataaaaattgcatggcgtatacttgcaaactggtggagttaacaaga
acctgtggaagtaagaatgggcagctcaagtgtgagcactgtacttcgctgcgcgatgaa
tacctgtgcttcgaaaattcctgcccaaaggccgatgaggtctgctcaggtggtggcttt
tgcgaggacggctttgctcagggtcctgctgccaagacttttctgagccctctggaggat
ttctcaggcaattgtgaagacgtagacgatttttttaaaagcaaaaaggagcggtccact
ttgttagtccgaaggttttgtaaaaatgacagggaagttaagaagtctgtgtatactggg
acaagagccatcatgagaactctgccttccggccgtattgggccggctgcttggaattat
gttgatcagaagaaagctggtctcctatggccttgtgggaatgtaatgggacctctgtca
gcaatggacataaggcaaagtgggagccaacgtctgactgaagcccagtggtgcctgatc
tacagtgccgtgagaagaggggaagaaacagaagaaacggtcggatctcttcgccattgc
gccacacagctcccaaactctgagacagcccatggaagtcttggagacggtccctgctta
aagcagtgtgtacgagacactgaatgtgagtaccgtgctaccctgcaaaggacgtccata
gctcagtacatcaccggttctctcctcgaggcaaccacatctttaggagcaagaagcggc
cttctcagtcccttcggaggatccactggacggataatgctgaaagaacgccaaccaggc
acctctatggccaattctaatcctgttccttcaagttcagctggaatcagcaaggagctg
attgatctccagcccctcattcagttcccggaggaagtggccagcatcttaacagagcag
gagcagaacatttaccgcagggtgctgcccatggactacctctgtttcttaacccgggac
ttgagttcacctgaatgccagagatcactgccccgtctcaaagcatccatctcagaatcc
atcctcacgtctcaaagtggagaacgcaatgcccttgaagaccttgtgatgagatttaac
gaggtgagctcctgggtaacgtggctggtcctcacggcaggctccatggaggagaagcgg
gaagtcttctcttatttggtgcatgtggccaaatgctgctggaacatgggcaactacaac
gctgtcatggagttcctggctggcctcaggtcaaggaaagttctaaagatgtggcagttc
atggaccagtctgacatcgagaccatgcggagcctgaaggatgccatggctcagcacgag
tcttccgtcgagtacaagaaggtagtgacccgagccttgcacatccccggctgcaaagtc
gtccctttctgtggggtgttcctgaaggagctctgtgaagtgctggatggtgcctctggt
ctcctgaagctctgcccacggtacagctcccaagaagaagctctggagtttgtagccgat
tacagtggacaagacaacttcttacaacgagtgggacagaatggcttaaagaattcagag
aaggagctcacggtcaacagcatctttcagatcatccggagctgcagccgaagtttggag
atggaggaggaggacagtgccagcgaagggagcggctctagaaaaaactccttgaaggac
aaagcccgatggcagtttataattggagatttgctggattcagaaaatgacatctttgag
aagtccaaagagtgtgaccctcatggatcagaggagtcacagaaagcctttgaccatggg
acggagctcatcccatggtacgtgctgtccatccaagcggatgtgcaccagttcctattg
cagggggccacagtcatccactatgaccaggacacacatctctccgcccgctgctttctc
cagttgcagcctgacaatagcacgttgacctggatgaaacctcccactgcctccccagcc
ggtgccagacccaagctcggcgtgcttagtaacacggccgagcccggcaagttcccatca
ccgggcaacgccggggtgagcggcctggcagagggaatcctggatctgttctcagtgaag
gctgtgtatatgggacaccctggcattgatatacacactgtgtgtgtccagaacaaactt
agtagcatgcttctatcggagacgggggtcaccctgctctatgggcttcagaccactgac
aatagattactgcactttgtggcgccaaagcacacagccgagatgcttttcagtggattg
ctggaacttactacagctgtgagaaagataaggaagttccctgaccaacgacagcagtgg
cttcggaaacagtatgtcagcctctatcaggaggatggtcggtatgaaggcccaaccttg
gcacatgctgtggagttgtttggtggtaggcggtggagcactagaaaccccagtcctgga
atgtcggcaaagaatgctgagaagcccaacatgcagagaaacaacaccctgggcataagc
accaccaagaaaaagaagaaaatgctcatgaggggagagagtggagaggtgacggacgat
gagatggctacccgcaaggccaaaatatacagagagtgtcgcagccggagcggctctgat
cctcaagacgttaacgaacaagaagagttggaggccaatgtcatcactaaccctcccaac
accctccattccagaagagcctactctttgaccacggctgggtcccccaacttggctacc
gggatgtcatctcccatcagtgcctggagcagcagcagctggcatgggcgaatccgagga
gggatgaaaggcttccagagcttcatggtttcagacagtaacatgagtttcgttgaattc
gttgagctgttcaaatcattcagcatcaggagccgcaaggacttgaaggacatctttgac
atctactccgtaccctgcaatcggtctgcctcggagtcagctccactctacaccaacctg
acaatcgaagaaaataccagtgaccttcagcctgacctagatttgctgactagaaacgtc
tccgacttggggctgttcattaaaagtaaacagcagctttctgacaaccagaggcagata
tctgatgctatcgctgctgcaagcattgtaaccaatggcactgggattgaaagcacgtcc
ctgggcatatttggggtcggcatactccagctcaatgatttcctggtgaattgccaagga
gaacactgcacgtatgatgaaatcctgagcatcatccagaaatttgagccgagcgtcagc
atgtgtcatcaaggcctattgtcatttgaagggtttgcaaggtttctgatggataaagac
aatttcgcctcaaaaaatgacgagtcacgggagaacaagaaagagctgcagctacccctc
tcctactattacattgagtcttcacacaacacctacctcaccggccatcagctcaagggg
gagtcctctgtggagctctatagccaggtcctcctgcaaggatgtagaagcatagagctg
gactgctgggatggggatgatgggatgcccatcatctatcatgggcatacactgacaacc
aagatccccttcaaggaagtggtggaagccatcgatcgcagtgccttcatcacctcagac
ctgccaatcatcatatccattgagaaccattgttcattgcctcaacaacgaaaaatggca
gaaattttcaagagtgtgtttggagaaaagctggtggctaagttcttattcgagaccgat
ttctcagatgacccaatgcttccctcacctgatcagcttagaaggaaagtgctccttaaa
aacaagaagctaaaggcccatcagacacctgtcgacatcctaaaacaaaaggctcatcag
ttagcatccatgcaagcacaggctttcactggtgggaatgccaacccgccacctgccagt
aatgaggaagaggaagatgaggaggacgaatatgattatgattacgagtccctttccgat
gcagatgtccttactgcttcccctgttcctaacagtcaggaagacaacattctggaagac
agacctgagaacaaattatgcgctgacaagcttcagtttgagtacaatgaagaaggccca
aagaggataaagaaagcagacaactcctctggcaataagggaaaggtgtatgacatggaa
ctgggagaggagttttaccttccacagaacaaaaaagaaagcaggcagattgcaccagag
ctctctgacctcgtcatttattgccaggcagtaaaatttccaggcctgtcaactctaaat
tcatctggctctagcagagggaaagaaaggaaaagcaggaagtccatttttggcaacaat
cctggcagaatgagcccaggggagacagcaccatttaacagaacatctggaaaaggttcc
tgtgaagggatgcgacaaacctgggaggaatcttctccactcagcccgagtacatccctc
agcgctatcattagaactcctaaatgctatcatatctcctcactgaatgagaacgccgcc
aaacgtctgtgccgcaggtgttctcagaaactgatccagcacaccgcttgccagctgctg
agaacctaccccgcagcgaccagaattgactcctccaatcccaaccccatcatattctgg
ctccatgggatacagcttgtagctctaaactaccagacggatgaccttcctttacattta
aacgctgccatgtttgaggccaatggtgggtgtggttacgttctgaagccccctgtcctg
tgggataaaagctgtcccatgtaccagaagttttccccactggaaagagacctagacacc
ctggatcctgctatctactctttaactatcatctctggccagaatgtgtgccctagtaac
agcaccggaagtccatgcattgaagttgacgtcttgggcatgcccctggacagctgccat
ttccgaacaaaacccatccatcgaaacactctgaatcccatgtggaatgagcagtttctc
ttccgggttcactttgaagatcttgtatttcttcgttttgcggttgtggaaaacaacagt
tcggcgataacagctcagagaatcattccactcagagctttaaaacgaggatatcgacat
cttcagctgcggaacctccacaatgaaatcttggaaatctctagcttattcataaacagc
agaaggatggaagaaaacccctctggcagtaccatgccagcctcattgatgtttaatacg
gaagagaggaaatgttctcagactcacaaagtcacagtgcatggtgtcccaggtccagag
ccctttgctgttttcactataaacgaaggcaccaaggcaaagcagcttctccaacaggtt
ttggaggttggccaaggcaccaaacatactgccacagactattttctgatggaagagaag
cattttatatctaaggaaaagaatgaatgcaggaaacaaccattccagagagctgtgggt
ccagaagaagatattgtgcagattttaaacagctggttcccagaagaaggctacgtaggc
aggattgtcttaaagccccaacaggaaaccttagaagagaagagcattgtctacgatgac
aaagaggtgatcttgagctcggaggaggagagtttctttgtccaagttcatgatgtctct
cctgagcaacctcgaactgtcatcaaagccccgcgtgtcagcactgcacaggatgtgatt
cagcagaccttatgcaaagccaagtattcctacagcatcctgaacaaccccaacccatgt
gactatgtgcttttggaagaggtgatgaaagacgcacctaataagaagtcttctacccca
aagtcctcacagaggatcctcttggaccaagaatgtgtgtttcaagcccaaagcaagtgg
aagggtgcagggaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagac
aaaaggaggggtatctcctttgcaaatgaactcaagaaactcactaagtccactaagcag
tcccgagggctcacgtcacctcctcagtttgtggcctcggaaagtgttcaaagcaaggag
gagaaacctgtgggtgccttggccgctggtgacacagtgggttaccagcagtga
DBGET
integrated database retrieval system
