Mus pahari (shrew mouse): 110322010
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Entry
110322010 CDS
T05929
Symbol
Cacna1s
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah04010
MAPK signaling pathway
mpah04020
Calcium signaling pathway
mpah04022
cGMP-PKG signaling pathway
mpah04024
cAMP signaling pathway
mpah04260
Cardiac muscle contraction
mpah04261
Adrenergic signaling in cardiomyocytes
mpah04270
Vascular smooth muscle contraction
mpah04723
Retrograde endocannabinoid signaling
mpah04725
Cholinergic synapse
mpah04726
Serotonergic synapse
mpah04727
GABAergic synapse
mpah04911
Insulin secretion
mpah04912
GnRH signaling pathway
mpah04921
Oxytocin signaling pathway
mpah04924
Renin secretion
mpah04925
Aldosterone synthesis and secretion
mpah04927
Cortisol synthesis and secretion
mpah04929
GnRH secretion
mpah04934
Cushing syndrome
mpah04935
Growth hormone synthesis, secretion and action
mpah05010
Alzheimer disease
mpah05020
Prion disease
mpah05022
Pathways of neurodegeneration - multiple diseases
mpah05207
Chemical carcinogenesis - receptor activation
mpah05410
Hypertrophic cardiomyopathy
mpah05412
Arrhythmogenic right ventricular cardiomyopathy
mpah05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110322010 (Cacna1s)
04020 Calcium signaling pathway
110322010 (Cacna1s)
04024 cAMP signaling pathway
110322010 (Cacna1s)
04022 cGMP-PKG signaling pathway
110322010 (Cacna1s)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
110322010 (Cacna1s)
04929 GnRH secretion
110322010 (Cacna1s)
04912 GnRH signaling pathway
110322010 (Cacna1s)
04921 Oxytocin signaling pathway
110322010 (Cacna1s)
04935 Growth hormone synthesis, secretion and action
110322010 (Cacna1s)
04924 Renin secretion
110322010 (Cacna1s)
04925 Aldosterone synthesis and secretion
110322010 (Cacna1s)
04927 Cortisol synthesis and secretion
110322010 (Cacna1s)
09153 Circulatory system
04260 Cardiac muscle contraction
110322010 (Cacna1s)
04261 Adrenergic signaling in cardiomyocytes
110322010 (Cacna1s)
04270 Vascular smooth muscle contraction
110322010 (Cacna1s)
09156 Nervous system
04727 GABAergic synapse
110322010 (Cacna1s)
04725 Cholinergic synapse
110322010 (Cacna1s)
04726 Serotonergic synapse
110322010 (Cacna1s)
04723 Retrograde endocannabinoid signaling
110322010 (Cacna1s)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
110322010 (Cacna1s)
09164 Neurodegenerative disease
05010 Alzheimer disease
110322010 (Cacna1s)
05020 Prion disease
110322010 (Cacna1s)
05022 Pathways of neurodegeneration - multiple diseases
110322010 (Cacna1s)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
110322010 (Cacna1s)
05412 Arrhythmogenic right ventricular cardiomyopathy
110322010 (Cacna1s)
05414 Dilated cardiomyopathy
110322010 (Cacna1s)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110322010 (Cacna1s)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mpah04040
]
110322010 (Cacna1s)
Ion channels [BR:
mpah04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
110322010 (Cacna1s)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
110322010
NCBI-ProteinID:
XP_021054226
Ensembl:
MGP_PahariEiJ_G0027886
LinkDB
All DBs
Position
5:110320739..110388532
Genome browser
AA seq
1786 aa
AA seq
DB search
MEPPSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNIIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTGASSTVNDA
IGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLEEDLR
GYMSWITQGEVMDVDDLREGKLSLDEGGSDTESLYEIEGLNKIIQFIRHWRQWNRVFRWK
CHDLVKSKVFYWLVILIVALNTLSIASEHHNQPVWLTHLQDVANRVLLTLFTIEMLMKMY
GLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITKYWTS
LSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQAL
ISVFQVLTGEDWNSVMYNGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIAVDNL
AEAESLTSAQKAKAEERKRRKMSKGLPDKSEEERATVTKKLEQKSKGEGIPTTAKLKIDE
FESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIFSP
TNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILEYFDYVFTAVFT
VEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLRVLRP
LRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCNDLSKMT
EEECRGYYYIYKDGDPTQIELRPRQWMHNDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAI
DSNEEDTGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELDKN
QRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYNQSE
QMNHISDILNVAFTIIFTLEMVLKLIAFKPRGYFGDPWNVFDFLIVIGSIIDVILSEIDT
FLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLVKLLNRAEGVRTLLWTFIKSF
QALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATGEA
WQEILLACSYGKLCDPESDYAPGEEYACGTNFAYYYFISFYMLCAFLIINLFVAVIMDNF
DYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVA
CKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMK
LLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLRTIEE
EAAPEIHRAISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMAN
QRPLQFAEIEMEELESPVFLEDFPQNPGTHPLARANTNNANANVAYGNSSHRNNPVFSSI
CYEKEFLEKADMPATGEGPFSQPCRVSGPHSRSHVDKLKRQMTQRRMPEGQVSPSLCQLS
QAEHPVQKEEKGPTSWSLGTPDSRNFEEHVPRNSAHRCTAPATAMLIQEALVRGGLDSLA
ADANFVMATGQALADACQMEPEEVEVAATELLKRESPEGGAMPWEP
NT seq
5361 nt
NT seq
+upstream
nt +downstream
nt
atggagccgccctcaccccaggacgagggcctgaggaagaagcagccgaagaaacctgtt
cctgagattctgccgaggcccccgcgggccttgttctgcctgactctccagaaccccctg
aggaaggcctgcatcagcatcgtggaatggaaacccttcgagaccatcatcttgctcacc
atctttgcgaactgcgtggccctggcagtgtacctgcccatgccagaggacgacaacaac
actctgaaccttggcctggagaaactggagtacttctttctcatcgtcttctccatcgaa
gccgccatgaagattatagcctatggcttcctattccatcaggatgcttacctgcgcagt
ggctggaatgtgctggacttcatcatcgtctttctgggggtcttcactgtaattctggaa
caagttaacatcattcaaaccaacacggcccccatgagcagcaaaggagccggcttggac
gtgaaggccctgcgagctttccgcgtgctcagacccctgcggctggtgtcaggggtgccc
agtcttcaggtggtcctcaactccatcttcaaggccatgctccccctgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctacgccatcattgggttggagctcttcaaaggc
aagatgcacaagacttgctacttcatcgggacaggagcctcctccactgtcaacgatgcc
attgggaatgagtggccctggatctattttgtcaccctcattctgctaggctccttcttc
atcctcaacctggtgctgggtgtcctgagtggagaattcaccaaggagcgagagaaggcc
aagtccagaggaactttccagaagctccgggagaaacagcagctggaggaggacctccgt
ggctacatgagctggatcacacagggcgaggtcatggatgtggatgacttgagagaaggc
aagctgtctttggatgaagggggctcagacacagaaagcttgtatgaaatcgaaggcttg
aacaaaatcatccagttcattcggcactggcggcagtggaatcgcgtcttccgctggaag
tgccatgacctagtgaaatccaaggtcttctattggctggtgatcctgattgttgcccta
aacaccctgtctattgcctcagagcaccacaaccagccagtctggctgacccatttgcaa
gatgtcgccaaccgtgtgctgctgaccctcttcaccattgaaatgctcatgaagatgtac
gggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgactgcttcgtggtg
tgcagcggcattctggagatcctgctggtggagtcaggagccatgacgcccctgggcatc
tctgtgctccgctgtatccgcctcctgaggctcttcaagatcaccaagtactggacatcg
ctgagcaacctggtggcctccctgctcaactccatccgctccatcgcttcgctcttgctg
ctgctctttcttttcatcatcatctttgccctgctgggcatgcagctctttggaggcaga
tatgactttgaagacacagaagtgcgacgaagcaactttgacaacttcccccaggccctc
atcagtgtcttccaggtcctgacaggtgaagactggaactctgtgatgtacaatgggatc
atggcttacggaggcccgacctaccctggcgtgctggtgtgcatttatttcatcattctt
ttcgtctgtggcaactacatccttctcaacgtcttcctggctatcgctgtggacaacctg
gcagaggcagagagtctgacatctgcccagaaggccaaggctgaggagagaaagcgcagg
aagatgtctaaagggctcccggacaagtcagaagaggagagggccacggtgaccaagaag
ctggagcagaagtccaagggcgaaggcatccccaccactgccaagctgaaaatcgatgag
tttgaatcgaacgtcaatgaggtgaaagacccttacccttcggctgactttccaggggac
gatgaggaagatgagcccgagatcccagtgagcccccgaccacgccctctggctgagctg
cagctgaaagagaaagcagtgcccatcccggaggccagctccttcttcatcttcagtccc
accaacaagatccgtgtcctgtgtcaccgcattgtcaatgccacctggttcaccaacttc
atcctgctcttcatcctgctcagcagtgctgccctggccgctgaggatcccatccgggcc
gactccatgaggaatcagatccttgagtattttgattatgtgttcactgctgttttcact
gtggagattgtccttaagatgaccacctacggagccttcctgcacaaaggctccttctgc
cgcaactacttcaacatcctggacctgctggtggtggctgtgtctctcatctccatgggc
ctcgagtccagcgccatctccgtggtgaagatcttaagggttctgagggtgctgagacca
ctccgggccatcaacagagccaaagggttgaagcacgtggtgcagtgcgtgtttgttgcc
attcgcaccatcgggaacatcgtgctggtcaccacgctcctgcagttcatgtttgcatgc
atcggagtgcagcttttcaagggaaagttctacagctgcaatgacttatccaagatgact
gaagaggaatgcaggggctactactacatatacaaggatggagaccccacacagatagag
ctgcgtccccgccagtggatgcacaacgactttcactttgacaatgtactctccgctatg
atgtcactcttcaccgtctccaccttcgagggttggcctcagctactgtacaaggccata
gactcaaatgaggaggacaccggccccgtctataacaaccgagtggagatggccatcttc
ttcattatctacatcatcctcatcgccttcttcatgatgaacatctttgtgggctttgtc
attgtcaccttccaggaacagggagagactgagtataagaactgtgagctggacaagaac
cagcgccaatgcgtacagtatgccctgaaggcccgcccactgaggtgttacatccccaaa
aacccataccagtatcaggtgtggtatgtcgtcacttcctcctactttgaatacctgatg
tttgctctcatcatgctcaataccatctgcctgggcatgcagcattacaaccagtcggaa
cagatgaaccacatctcagacattctcaacgtggctttcaccatcatcttcaccctggag
atggtcctcaagctcatagctttcaagccaaggggctattttggagacccctggaatgtg
tttgacttcctgatcgtcatcggcagcatcattgacgtcatcctgagcgagatcgatact
ttcctggcctccagcgggggactgtattgcctgggtggaggctgcgggaacgttgaccca
gatgagagtgcccgcatctccagtgccttcttccgcctgttccgggtcatgagactggtc
aagctgctgaaccgggcagagggtgtgcgcaccctgctgtggacgttcatcaagtccttc
caggccctgccatatgtggctttgctgatcgtaatgctcttcttcatctacgcggtcatc
ggcatgcagatgttcgggaaaatcgccatggtggatgggacacagataaaccggaacaac
aacttccagactttcccacaagctgtgctgctgctcttcaggtgtgccacaggggaagcc
tggcaagagatcctgctggcctgcagctacgggaagctgtgtgacccggagtctgactac
gcgcccggggaggagtatgcgtgtggcaccaactttgcctactactacttcatcagcttc
tacatgctctgcgccttcctgatcatcaacctctttgtggctgtcatcatggacaacttt
gactacctcacaagggactggtccattctgggccctcaccacctggatgagttcaaggcc
atctgggctgagtatgacccagaggctaagggcaggatcaagcacctggatgtggtgacc
ctgctgaggagaatccagccccctctgggctttgggaagttctgcccacacagggtagca
tgtaagaggctggtgggcatgaacatgcccctgaacagcgatggcacagtcacctttaat
gccacactatttgccctggtgcgcacagccctcaagatcaagacggaaggcaactttgaa
caagccaatgaggagctgagagccatcatcaagaagatctggaagagaaccagcatgaag
ctcttggaccaagtcatccctccaataggagatgatgaggtgacagtgggaaagttctat
gccacattcctcatccaggagcacttccggaagttcatgaagcgccaggaggaatattat
gggtatcgacccaaaaaggacacagttcagatacaggctggattacggaccatagaggaa
gaggcagctcctgagatccaccgtgccatctctggagacctgacagcagaggaggaactg
gagagggccatggtagaggctgccatggaggaggggatattccggaggaccggaggcctg
tttggtcaagtggacaacttcctggaaaggaccaactctctgccccctgtcatggccaac
caaagacccctccaatttgctgaaatagagatggaagagctggagtcaccggtcttcttg
gaggacttccctcagaacccaggcacccaccctcttgctcgtgccaataccaacaacgcc
aatgccaatgttgcctatggcaacagcagccatagaaacaacccagtgttttccagcatc
tgctatgaaaaggagttcctggaaaaggcagacatgccggctactggagaaggacccttc
agtcagccctgcagggtctcaggacctcacagcagatcccatgtggacaaactgaaaaga
cagatgacccagagaagaatgcctgaaggccaggtgtcaccttccctgtgccagctctcc
caggcagagcatcctgtgcagaaagaggaaaagggccccacgtcatggtctctgggaaca
cccgacagcaggaactttgaagagcatgttcccaggaattcggctcacaggtgcacggct
ccagctactgccatgctgatccaggaggctctggttcgaggaggactagactccttagca
gcagatgctaacttcgtcatggcaacaggccaggccctggcagatgcctgccagatggaa
ccagaggaagtcgaggtggcagcaacagagctactgaagcgagaatccccagagggcggg
gctatgccctgggagccttga
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