Mus pahari (shrew mouse): 110324314
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Entry
110324314 CDS
T05929
Symbol
Sos2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah01521
EGFR tyrosine kinase inhibitor resistance
mpah01522
Endocrine resistance
mpah04010
MAPK signaling pathway
mpah04012
ErbB signaling pathway
mpah04014
Ras signaling pathway
mpah04062
Chemokine signaling pathway
mpah04068
FoxO signaling pathway
mpah04072
Phospholipase D signaling pathway
mpah04150
mTOR signaling pathway
mpah04151
PI3K-Akt signaling pathway
mpah04510
Focal adhesion
mpah04540
Gap junction
mpah04630
JAK-STAT signaling pathway
mpah04650
Natural killer cell mediated cytotoxicity
mpah04660
T cell receptor signaling pathway
mpah04662
B cell receptor signaling pathway
mpah04664
Fc epsilon RI signaling pathway
mpah04714
Thermogenesis
mpah04722
Neurotrophin signaling pathway
mpah04810
Regulation of actin cytoskeleton
mpah04910
Insulin signaling pathway
mpah04912
GnRH signaling pathway
mpah04915
Estrogen signaling pathway
mpah04917
Prolactin signaling pathway
mpah04926
Relaxin signaling pathway
mpah04935
Growth hormone synthesis, secretion and action
mpah05034
Alcoholism
mpah05160
Hepatitis C
mpah05161
Hepatitis B
mpah05163
Human cytomegalovirus infection
mpah05165
Human papillomavirus infection
mpah05200
Pathways in cancer
mpah05205
Proteoglycans in cancer
mpah05206
MicroRNAs in cancer
mpah05207
Chemical carcinogenesis - receptor activation
mpah05208
Chemical carcinogenesis - reactive oxygen species
mpah05210
Colorectal cancer
mpah05211
Renal cell carcinoma
mpah05213
Endometrial cancer
mpah05214
Glioma
mpah05215
Prostate cancer
mpah05220
Chronic myeloid leukemia
mpah05221
Acute myeloid leukemia
mpah05223
Non-small cell lung cancer
mpah05224
Breast cancer
mpah05225
Hepatocellular carcinoma
mpah05226
Gastric cancer
mpah05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110324314 (Sos2)
04012 ErbB signaling pathway
110324314 (Sos2)
04014 Ras signaling pathway
110324314 (Sos2)
04630 JAK-STAT signaling pathway
110324314 (Sos2)
04068 FoxO signaling pathway
110324314 (Sos2)
04072 Phospholipase D signaling pathway
110324314 (Sos2)
04151 PI3K-Akt signaling pathway
110324314 (Sos2)
04150 mTOR signaling pathway
110324314 (Sos2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110324314 (Sos2)
04540 Gap junction
110324314 (Sos2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110324314 (Sos2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
110324314 (Sos2)
04660 T cell receptor signaling pathway
110324314 (Sos2)
04662 B cell receptor signaling pathway
110324314 (Sos2)
04664 Fc epsilon RI signaling pathway
110324314 (Sos2)
04062 Chemokine signaling pathway
110324314 (Sos2)
09152 Endocrine system
04910 Insulin signaling pathway
110324314 (Sos2)
04912 GnRH signaling pathway
110324314 (Sos2)
04915 Estrogen signaling pathway
110324314 (Sos2)
04917 Prolactin signaling pathway
110324314 (Sos2)
04926 Relaxin signaling pathway
110324314 (Sos2)
04935 Growth hormone synthesis, secretion and action
110324314 (Sos2)
09156 Nervous system
04722 Neurotrophin signaling pathway
110324314 (Sos2)
09159 Environmental adaptation
04714 Thermogenesis
110324314 (Sos2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110324314 (Sos2)
05206 MicroRNAs in cancer
110324314 (Sos2)
05205 Proteoglycans in cancer
110324314 (Sos2)
05207 Chemical carcinogenesis - receptor activation
110324314 (Sos2)
05208 Chemical carcinogenesis - reactive oxygen species
110324314 (Sos2)
05231 Choline metabolism in cancer
110324314 (Sos2)
09162 Cancer: specific types
05210 Colorectal cancer
110324314 (Sos2)
05225 Hepatocellular carcinoma
110324314 (Sos2)
05226 Gastric cancer
110324314 (Sos2)
05214 Glioma
110324314 (Sos2)
05221 Acute myeloid leukemia
110324314 (Sos2)
05220 Chronic myeloid leukemia
110324314 (Sos2)
05211 Renal cell carcinoma
110324314 (Sos2)
05215 Prostate cancer
110324314 (Sos2)
05213 Endometrial cancer
110324314 (Sos2)
05224 Breast cancer
110324314 (Sos2)
05223 Non-small cell lung cancer
110324314 (Sos2)
09172 Infectious disease: viral
05161 Hepatitis B
110324314 (Sos2)
05160 Hepatitis C
110324314 (Sos2)
05163 Human cytomegalovirus infection
110324314 (Sos2)
05165 Human papillomavirus infection
110324314 (Sos2)
09165 Substance dependence
05034 Alcoholism
110324314 (Sos2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110324314 (Sos2)
01522 Endocrine resistance
110324314 (Sos2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
PH_19
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
110324314
NCBI-ProteinID:
XP_021057426
Ensembl:
MGP_PahariEiJ_G0029564
LinkDB
All DBs
Position
7:complement(65104558..65191900)
Genome browser
AA seq
1333 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVPALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
MAQPRTIQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
DIGLVSLCEDEPCSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLLDRKLFKPSE
IEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQD
ILAPEFNDHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLK
ACSEEQDDKECLNQAITALMNLQGSMDRIYKQHSPRRRPGDPVCLFYNRQLRSKHLAIKK
MNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRLP
GYSSAEYRLKEKFVMRKIQICDKEDACEYRHAFELVSKDENSVIFAAKSAEEKNNWMAAL
ISLHYRSTLDRMLDSVLLKEENEQPLRLPSPDVYRFVVTDSEENIVFEDNLQSRSGIPII
KGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKL
ALEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLESFISSV
RGKAMKKWVESIAKIIKRKKQAQANGISHNITFESSPPPVEWHISRTGQFETFDLMTLHP
IEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVE
AENFEERVAVLSRIVEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRIL
DDAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNSDFLKRKGKDLINFSKR
RKVAEITGEIQQYQNQPYCLRTEPEMRRFFENLNPMGILSEKEFTDYLFNKSLEIEPRNC
KQPPRFPRKSTFSLKSPGIRPNAGRHGSTSGTLRGHPTPLEREPYKISFSRIAETELEST
VSAPTSPNTPSTPPVSASSDHSVFLDVDLSSSCGSNTIFAPVLLPHSKTFFSSCGSLHKL
SEEPLIPPPLPPRKKFDHDAPNSKGAMRSDDDPPAIPPRQPPPPKVKPRVPVLMGTFDGP
VLSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFTLQPPPLGHPHRDPDWLRDVSTCPNSP
STPPTTPSPRIPRSCHLLSSSHSSLAHPSAPPVPPRQNSSPHLPKLPPKTYKRELSHPPL
YRLPLLENAETPQ
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgagttcttcagcgaagaaaacagcccgaaatggcgg
ggactgttggtcccggccttgcggaaggttcaggagcaagtacatcccaccctgtcagct
aatgaagagtctctctattatattgaagaactgatttttcagctgcttaataaactatgc
atggctcaaccaaggactattcaagatgttgaggaacgagttcaaaagacctttcctcat
cctattgataaatgggcaattgctgatgcacagtctgccatagagaaacgaaaacgaaga
aatcctcttttactacctgtggacaaaatccacccttccttgaaggaagttttggggtat
aaagtggactaccatgtatccctctatattgtggctgtattggagtatatctcagcagat
attttgaaattggctggtaattacgtctttaatattcgacattatgaaatatctcagcaa
gatattaaagtgtccatgtgtgcagataaggttttgatggacatgtttgatcaggatgat
gatataggcttggtttctctctgtgaagatgaaccttgttcttctggtgagctaaactat
tatgaccttgtcaggactgaaattgcagaagaaagacagtatctacgggagctgaatatg
atcattaaagtgttccgggaagcctttctcttggacagaaagttgttcaagccttctgaa
attgaaaagattttcagtaacatttcagatatacatgaactgactgtgaaacttttaggt
ttaattgaagacacagtagagatgacagatgagagcagtcctcacccattagctggcagc
tgttttgaagacttagcagaggagcaagcgtttgatccctatgaaacattatcacaggac
attcttgcaccagagtttaatgaccacttcagcaagttgatggccagacctgcagttgct
ctacattttcagtccattgctgacggctttaaggaggctgttcgttatgtccttccacgc
ctcatgctggtgccggtgtatcactgttggcattactttgaattattaaagcagttgaag
gcatgcagtgaagagcaggacgacaaagagtgcttgaatcaggctatcactgccctcatg
aacctccaaggcagcatggaccgcatttacaagcagcactcccccagacgccggcctggg
gatcccgtttgccttttttacaatcgtcaattaagaagcaagcacctggctatcaaaaaa
atgaatgaaattcagaaaaacatagatgggtgggaaggcaaagatattggacagtgttgt
aatgagttcataatggagggaccattgaccagaattggtgctaaacatgaaaggcatatt
tttctctttgatggcttaatgatcagctgtaaacccaatcatggccagacccggcttcca
ggttatagcagtgcagaatacagattaaaggagaagtttgtcatgaggaaaattcaaatc
tgtgataaagaagacgcctgtgagtacagacatgcttttgaattagtgtccaaagatgaa
aacagtgtaatatttgctgccaagtcagctgaagagaaaaacaactggatggcagccctc
atttccctgcactatcgcagcactctagacagaatgctggactctgtgctgctgaaagaa
gagaatgagcagcccctgaggctacccagtccagatgtgtatcgctttgtggtaacagac
tctgaggaaaacattgtgtttgaagacaacttgcaaagcagaagtgggatccccataatt
aaaggaggcactgtggtgaaactgattgaaaggctaacataccacatgtatgcagatccc
aattttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgcta
agcttgctgatagaacggtttgaaattccagaaccagaacctactgaggcagacaagctg
gcgttagagaaaggcgagcagccaatcagcgcagatctgaaaagattccgaaaggaatac
gtccaacctgtgcaacttagggtcttgaatgtctttcgccactgggtcgagcatcatttt
tatgactttgaaagagacttggaattgcttgaaagactagaatccttcatttcaagtgta
agagggaaagccatgaagaaatgggtagaatccattgctaaaattatcaaaaggaagaag
caagctcaggcaaatggaataagccataatatcacctttgaaagttcacctccaccagtg
gaatggcacataagtagaacaggacagtttgaaacatttgaccttatgacacttcatcca
atagagattgcacggcagctaacgcttttggaatctgacctctacaggaaagtccagccc
tctgaacttgtagggagtgtctggaccaaagaagataaagaaataaattctccaaattta
ttaaaaatgattcgtcatacaacaaacctcactctgtggtttgagaaatgcattgtggaa
gcagaaaactttgaagaacgggtggcagtgctcagcagaatagtagaaattctgcaagtg
tttcaagacttgaataatttcaatggtgtgttggagatagtgagtgctgtcaattccgtg
tcagtgtacaggctagaccacacgtttgaggcattgcaggaaaggaagcggagaattttg
gatgacgccgtggaactaagtcaggatcactttaaaaaatacctagtaaaacttaaatca
atcaatccgccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaa
gaagggaatagtgactttctaaagaggaaagggaaagatttgatcaatttcagtaagagg
aggaaagtggctgaaataactggagagattcagcagtatcagaaccaaccgtactgctta
cggacagaaccagaaatgaggagattctttgaaaacctcaaccccatgggaattttatct
gaaaaagagtttacagattatttgttcaacaaatcactagaaatcgaaccccgaaactgc
aaacaaccacctcgatttcctaggaagtccaccttttccttaaaatctcctggaataagg
cccaatgctggccgccatggctctacctcaggcacgttacgaggtcacccaacccctctg
gaaagagagccttataagataagctttagccggatcgctgagacagagctagaatcgaca
gtgtcggcaccaacctctcccaacactccatccaccccaccagtgtccgcttcttctgac
cacagcgtattcctagatgtggacctcagtagctcctgcggcagcaataccatctttgct
ccagtcctcttgccacactcaaagactttcttcagctcatgtggaagtttacacaaactg
agtgaagagccactaattcctcctccgctgccccctcggaaaaagtttgatcatgatgct
cccaattctaagggagctatgagatctgatgatgaccctcctgctattccaccaagacag
cccccgcctccaaaggtaaagccaagagttcctgtcctcatgggtacatttgatgggcct
gtgctcagtccacctccacctcctccaagagaccctcttcctgatacccctccaccagtt
cctcttcggcctccggaacactttataaactgtccatttactcttcagccacctccactg
ggccatcctcacagagacccagactggctcagagacgttagcacgtgtcctaactcacca
agcactcctcccaccacgccctctccacggattccacgcagctgtcacttgctcagctcc
agtcacagcagccttgctcatccttcagctcctcctgttccaccaaggcagaattcaagc
cctcacttaccaaagctgccaccaaagacttacaaacgggagctttcccacccgccactg
tacagactgcctctgcttgaaaatgcagaaactcctcaatga
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