Mus pahari (shrew mouse): 110325961
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Entry
110325961 CDS
T05929
Symbol
Cacna1d
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah04010
MAPK signaling pathway
mpah04020
Calcium signaling pathway
mpah04022
cGMP-PKG signaling pathway
mpah04024
cAMP signaling pathway
mpah04218
Cellular senescence
mpah04260
Cardiac muscle contraction
mpah04261
Adrenergic signaling in cardiomyocytes
mpah04270
Vascular smooth muscle contraction
mpah04530
Tight junction
mpah04713
Circadian entrainment
mpah04723
Retrograde endocannabinoid signaling
mpah04724
Glutamatergic synapse
mpah04725
Cholinergic synapse
mpah04726
Serotonergic synapse
mpah04727
GABAergic synapse
mpah04728
Dopaminergic synapse
mpah04911
Insulin secretion
mpah04912
GnRH signaling pathway
mpah04921
Oxytocin signaling pathway
mpah04924
Renin secretion
mpah04925
Aldosterone synthesis and secretion
mpah04927
Cortisol synthesis and secretion
mpah04929
GnRH secretion
mpah04930
Type II diabetes mellitus
mpah04934
Cushing syndrome
mpah04935
Growth hormone synthesis, secretion and action
mpah04973
Carbohydrate digestion and absorption
mpah05010
Alzheimer disease
mpah05020
Prion disease
mpah05022
Pathways of neurodegeneration - multiple diseases
mpah05031
Amphetamine addiction
mpah05207
Chemical carcinogenesis - receptor activation
mpah05410
Hypertrophic cardiomyopathy
mpah05412
Arrhythmogenic right ventricular cardiomyopathy
mpah05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110325961 (Cacna1d)
04020 Calcium signaling pathway
110325961 (Cacna1d)
04024 cAMP signaling pathway
110325961 (Cacna1d)
04022 cGMP-PKG signaling pathway
110325961 (Cacna1d)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
110325961 (Cacna1d)
09144 Cellular community - eukaryotes
04530 Tight junction
110325961 (Cacna1d)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
110325961 (Cacna1d)
04929 GnRH secretion
110325961 (Cacna1d)
04912 GnRH signaling pathway
110325961 (Cacna1d)
04921 Oxytocin signaling pathway
110325961 (Cacna1d)
04935 Growth hormone synthesis, secretion and action
110325961 (Cacna1d)
04924 Renin secretion
110325961 (Cacna1d)
04925 Aldosterone synthesis and secretion
110325961 (Cacna1d)
04927 Cortisol synthesis and secretion
110325961 (Cacna1d)
09153 Circulatory system
04260 Cardiac muscle contraction
110325961 (Cacna1d)
04261 Adrenergic signaling in cardiomyocytes
110325961 (Cacna1d)
04270 Vascular smooth muscle contraction
110325961 (Cacna1d)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110325961 (Cacna1d)
09156 Nervous system
04724 Glutamatergic synapse
110325961 (Cacna1d)
04727 GABAergic synapse
110325961 (Cacna1d)
04725 Cholinergic synapse
110325961 (Cacna1d)
04728 Dopaminergic synapse
110325961 (Cacna1d)
04726 Serotonergic synapse
110325961 (Cacna1d)
04723 Retrograde endocannabinoid signaling
110325961 (Cacna1d)
09159 Environmental adaptation
04713 Circadian entrainment
110325961 (Cacna1d)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
110325961 (Cacna1d)
09164 Neurodegenerative disease
05010 Alzheimer disease
110325961 (Cacna1d)
05020 Prion disease
110325961 (Cacna1d)
05022 Pathways of neurodegeneration - multiple diseases
110325961 (Cacna1d)
09165 Substance dependence
05031 Amphetamine addiction
110325961 (Cacna1d)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
110325961 (Cacna1d)
05412 Arrhythmogenic right ventricular cardiomyopathy
110325961 (Cacna1d)
05414 Dilated cardiomyopathy
110325961 (Cacna1d)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110325961 (Cacna1d)
04934 Cushing syndrome
110325961 (Cacna1d)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mpah04040
]
110325961 (Cacna1d)
Ion channels [BR:
mpah04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
110325961 (Cacna1d)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
110325961
NCBI-ProteinID:
XP_021059785
Ensembl:
MGP_PahariEiJ_G0030066
LinkDB
All DBs
Position
8:complement(21338204..21641788)
Genome browser
AA seq
2180 aa
AA seq
DB search
MMMMMMMKKMQHQRQHQEDHANEANYARGTRLPISGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKESEGGNHSGGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVS
GEGETQGCCGTLWCWWKRRGAAKTGPSGCRRWGQAISKSKLSRRWRRWNRFSRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYQEDAEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIVPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
VYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPSESETIPLP
TATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAML
FFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKL
CDPDSDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPH
HLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNS
DGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDE
VTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISC
DLQDDEPEESKPEEEDLFKRNGAPLGNHVNHVNSDRRESLQHTNTTHRPLHVQRPSMPPA
SDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHAS
ENGHYSCKHDRELQRRSSIKRTRYYETYIRSESGDEQFPTICREDPEIHGYFRDPRCLGE
QEYFSSEECCEDDSSPTWSRQNYSYYNRYPGSSMDYERPRGYHHPQGFLEDDDSPTGYDS
RRSPRRRLLPPTPPSHRRSSFNFECLRRQSSQDDDVLPSPALPHRAALPLHLMQQQIMAV
AGLDSSKAQKYSPSHSTRSWATPPATPPYRDWSPCYTPLIQVDRSESMDQVNGSLPSLHR
SSWYTDEPDISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFV
SATKHEIADACDLTIDEMESAASTLLNGSVCPRANGDMGPISHRQDYELQDFGPGYSDEE
PDPGREEEDLADEMICITTL
NT seq
6543 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcaacatcaacggcagcaccaagaggaccat
gcgaacgaggcaaactatgcaagaggcaccagactccctatttctggtgaaggaccaact
tctcagcccaacagctccaagcaaactgtcctatcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccagaccatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtctaacagc
cgacctgcccgtgcccttttctgtttatccctcaacaaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtggagacatttctgaagatt
atagcgtatggactgttgctgcatcctaatgcttacgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
tcagaaggcgggaaccactctggcggcaaatcaggaggctttgatgtcaaagccctccgt
gccttccgagtgttaagaccacttcgacttgtatcaggagtgcccagtttacaagttgtt
ctgaactccattataaaagccatggtccccctccttcacatagcccttttggtattattt
gtaattatcatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatatagtagctgaagaggacccagctccatgtgcgttctca
gggaatggacgccagtgcaccgccaatggcacggaatgtaggagtggctgggttggcccc
aatggaggcatcactaactttgataactttgcctttgccatgctcactgtgttccagtgc
attaccatggagggctggacggatgtgctctactgggttaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctccaaggaaagagagaaggctaaagcccgtgga
gacttccagaagcttcgggaaaagcagcagctggaagaggatctcaagggctacctggac
tggatcacccaggcagaagacatagatcctgagaacgaagaggagggtggcgaggaaggc
aaacgaaacactagcatgcccaccagcgagactgaatctgtgaacacagagaacgtaagt
ggtgaaggcgagacccagggatgctgcggaactctctggtgctggtggaaaagaagaggc
gcggccaagactgggccctctgggtgtcggcggtggggtcaggccatctcgaaatccaaa
ctcagccgtcgctggcgtcgctggaaccggttcagtcgcaggaggtgcagggctgctgtg
aagtctgtcacgttttactggctggtgatcgtcctggtgtttctcaacactttaactata
tcctccgagcattacaatcagccagactggctgacacagattcaagacatcgcgaacaaa
gtcctcttggctctgttcacctgtgagatgctggtgaagatgtacagcctgggcctccag
gcttacttcgtctccctcttcaaccgctttgattgctttgtggtgtgtgggggcatcacc
gaaaccatcctggtggaactggagctcatgtcccccctgggggtctccgtgttccggtgt
gtgcgcctcctgagaatcttcaaagtgaccaggcactggacttccctgagcaacttggtg
gcatccttgttaaactccatgaagtccatcgcctccctgctgctgctgctcttcctcttc
atcatcatcttctccctgctggggatgcagctgtttgggggaaagtttaattttgatgag
actcaaaccaagcgaagcacctttgacaactttccgcaagcactcctgactgtgttccag
atcctgacaggcgaagactggaatgcggtgatgtatgacggcatcatggcctacggaggc
ccttcctcttccgggatgatcgtctgtatctacttcatcatccttttcatctgtggtaac
tatatcctgctgaacgtcttcttggccatcgctgtggacaatttggctgatgctgaaagt
ctgaacactgctcagaaagaggaagcagaagaaaaagaaaggaaaaaaattgccagaaaa
gaaagcctagaaaacaaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aacaaggttacaattgatgattatcaggaagatgctgaagataaggacccttacccgccc
tgtgatgtgccagtaggtgaagaggaagaggaggaggaagaggatgagcccgaagttcct
gctggtccccgccctcgcagaatctcagagttgaacatgaaggagaagattgtgcccatc
cccgaaggaagcgcgttcttcattcttagcaagaccaacccgatccgtgtgggttgccac
aagctcattaaccaccacatcttcaccaaccttatcctggtcttcatcatgctgagcagc
gctgccctggccgcagaggatcccatccgtagccactcattccgcaacactattctgggc
tactttgactatgccttcacagccatctttacagttgaaatcctgttaaagatgacaact
tttggagccttcttgcacaaaggggctttctgcaggaactacttcaatttgctggacatg
ctggttgttggggtgtcgctggtgtccttcgggattcaatccagcgccatctccgttgtg
aagattctgagggttttgagggtcttgaggcctctcagagcaatcaacagagcaaaagga
cttaagcacgtggtccagtgtgtctttgtggccatccgaaccattggcaacatcatgatt
gtcacgaccctgctccagttcatgtttgcatgcattggggtccagctgttcaaggggaag
ttctaccgttgcacagatgaagccaaaagtaaccctgaggagtgcagggggcttttcatt
ctttataaggacggcgatgttgacagtcctgtggtccgtgagaggatctggcaaaacagt
gatttcaattttgacaatgtcctttcggctatgatggcgctcttcacggtctcaactttt
gagggctggcccgcgttgctgtacaaagctattgattcaaacggggagaatgttggtcct
gtctataactaccgtgtggagatctccatcttcttcatcatttacatcatcatcgttgcc
ttctttatgatgaacatctttgtgggcttcgtcatcgtcaccttccaggaacagggagaa
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatatgccttg
aaagcacgccccttaaggagatacatccccaaaaacccataccagtacaagttctggtac
gtggtgaactcctcacctttcgaatacatgatgttcgtcctcatcatgctcaacacgctc
tgcctggccatgcagcactatgagcagtccaagatgttcaatgatgctatggacattctg
aacatggtctttacaggggtcttcactgttgagatggttttgaaagtcattgctttcaag
cccaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgacccatctgaaagtgagactatccctctccca
actgccacacccgggaactctgaagagagcaatagaatctccatcacctttttccgtctt
ttccgagtgatgcggttggtgaaactcctcagcaggggggaaggcatccggacactgctg
tggaccttcatcaagtcctttcaggcactaccgtatgtcgccctcctcatcgccatgctc
ttcttcatctatgctgtcattggcatgcagatgtttgggaaagttgccatgagagataac
aaccagatcaataggaacaacaacttccagacatttcctcaggcggtcctactgctcttc
aggtgtgcaaccggggaagcctggcaggagatcatgcttgcctgcctcccggggaagctg
tgcgacccagactcggattacaacccgggagaggagtacacttgtgggagcaactttgcc
attgtctacttcatcagtttttacatgctctgtgcattcctgatcatcaacctctttgtg
gctgtcatcatggacaattttgactatctgactcgggactggtctattctggggcctcac
cacttggacgaattcaaaagaatatggtcagaatatgaccctgaagcaaagggaaggata
aaacacctcgatgtggtcactctgctccgacggatccagcctcccctggggtttggaaag
ttatgcccacaccgagtagcgtgtaagagattggttgccatgaacatgcctctcaacagt
gatgggacagtcatgttcaatgcaaccctgtttgctttggtccggacagctctcaagatc
aagactgaagggaacctggagcaagctaatgaagaactccgagctgtgataaagaaaatc
tggaagaagacaagcatgaagctgctggaccaagttgtccctccagctggtgatgatgag
gtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaag
aaacggaaagagcaaggactggtggggaagtaccctgcgaagaacaccacaattgcccta
caggcgggattaaggaccctgcatgacattgggccagaaatccgacgggctatatcctgt
gacttgcaagatgacgagccagaagaatccaaaccagaagaagaagatttgttcaaaaga
aatggtgccccgcttggaaaccatgtcaatcatgttaatagtgataggagagagtccctt
cagcacaccaataccacccaccgtcccctgcatgtccaaaggccttcaatgccacctgca
agtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccatcat
aaccataattccatagggaagcaagttcccacctcaacaaatgccaatctcaataatgcc
aatatgtccaaagctgcccacggaaagcggcccagcattgggaacctcgagcacgcgtct
gaaaatgggcattactcctgcaagcatgatcgagagctccaaagaaggtccagtattaaa
agaacccgctattatgagacttacattaggtctgagtcaggagatgagcagtttccaacc
atttgccgtgaagaccctgagatccacggctacttccgagacccccgctgcttgggggaa
caggaatatttcagtagcgaggagtgctgtgaggatgacagttctcccacctggagcagg
caaaactacagctactacaacaggtacccaggcagctccatggactatgagaggccccga
ggctaccaccacccccaaggcttcttagaagatgatgactctcccactggctatgattca
cggagatctccgaggagacgtcttctacctcctaccccaccatcccatcggaggtcctcc
ttcaactttgagtgtctacgcaggcaaagcagccaagacgacgacgtccttccatcacct
gccctgcctcaccgtgctgctctgcccctgcacctgatgcagcagcagatcatggcagtt
gcaggcctagattccagtaaagcccagaagtactcaccgagccactctacccggtcatgg
gccacccctccagcaacccctccataccgagactggagcccatgctacacccctttgatc
caggtggaccgctcagagtctatggaccaggtcaatggcagcctgccgtccctacaccgc
agctcctggtacacagatgaacctgacatctcctataggactttcacgccagccagtctg
actgttcccagcagcttccggaacaaaaacagcgacaagcagaggagtgcagacagcctg
gtggaggcagtcctgatatctgaaggcttgggacgctacgcgagggaccccaaatttgtc
tcagcgacaaaacatgagattgctgatgcctgtgacctaaccatagacgagatggaaagt
gcagccagcaccctgctcaatggcagcgtgtgccctcgagccaacggggacatgggcccc
atctcacaccgccaggactatgagctccaggactttggtcctggctacagtgacgaggag
ccagaccctgggcgagaggaagaggacctggcagatgaaatgatttgcattaccaccttg
tag
DBGET
integrated database retrieval system
