Mus pahari (shrew mouse): 110327406
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Entry
110327406 CDS
T05929
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah04217
Necroptosis
mpah04380
Osteoclast differentiation
mpah04620
Toll-like receptor signaling pathway
mpah04621
NOD-like receptor signaling pathway
mpah04630
JAK-STAT signaling pathway
mpah04658
Th1 and Th2 cell differentiation
mpah04659
Th17 cell differentiation
mpah05145
Toxoplasmosis
mpah05160
Hepatitis C
mpah05161
Hepatitis B
mpah05162
Measles
mpah05164
Influenza A
mpah05165
Human papillomavirus infection
mpah05167
Kaposi sarcoma-associated herpesvirus infection
mpah05168
Herpes simplex virus 1 infection
mpah05169
Epstein-Barr virus infection
mpah05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
110327406 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
110327406 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110327406 (Tyk2)
04621 NOD-like receptor signaling pathway
110327406 (Tyk2)
04658 Th1 and Th2 cell differentiation
110327406 (Tyk2)
04659 Th17 cell differentiation
110327406 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
110327406 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
110327406 (Tyk2)
05160 Hepatitis C
110327406 (Tyk2)
05171 Coronavirus disease - COVID-19
110327406 (Tyk2)
05164 Influenza A
110327406 (Tyk2)
05162 Measles
110327406 (Tyk2)
05168 Herpes simplex virus 1 infection
110327406 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
110327406 (Tyk2)
05169 Epstein-Barr virus infection
110327406 (Tyk2)
05165 Human papillomavirus infection
110327406 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110327406 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpah01001
]
110327406 (Tyk2)
Enzymes [BR:
mpah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
110327406 (Tyk2)
Protein kinases [BR:
mpah01001
]
Non-receptor tyrosine kinases
JAK family [OT]
110327406 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
110327406
NCBI-ProteinID:
XP_021062030
Ensembl:
MGP_PahariEiJ_G0014727
LinkDB
All DBs
Position
10:complement(16464307..16489686)
Genome browser
AA seq
1208 aa
AA seq
DB search
MVGSMPLCGRRATLKDSKADGTDFQPLVPTGRLMVLLHWPGPKGGEPWVTFSQTSLTAEE
VCIHIAHKVGITPPCLNLFALYNAQANVWLPPNHILDASQDVSLYFRVRFYFRNWHGMHP
QEPAVYRCGFPGAENSSDRAEQGVQLLDSASFEYLFEQVWFVGNRAKSSHTSFSIHPSSP
QGKHDFMNDVVSLRDLSSEEEIHHFKNESLGMAFLHLCHLALSRGVPLEEMAREISFENC
IPHSFRQHIRQHNVLTRLRLRRVFRRFLRAFRPGHLSQQVVMVKYLATLERLAPRFGSER
IPVCHLEVLAQPERDPCYIQNSGQTTGDPGPELPSGPPTHEVLVTGTGGIQWHPLQTQES
ERSNSRENPQGSSRSGKKPKGPEAGERLAESPQEPPWTYFCDFQDISHVVLKERRVHIHL
QDNKCLLLCLCSQAEALSFVALVDGYFRLTADSSHYLCHEVAPPRLVTSIQNGIHGPLMD
PFVQAKLWPEDGLYLIQWSTSHLHRLILTVAHRNPAPGNGPRGLRLRKFPITQQPGAFVL
DGWGRSFDSLGDLRLALQGCSLRAGDDCFPLHHCCLPRPREISNLVIMRGSRAHTRPLNL
SQLSFHRVHQDEITQLSHLGQGTRTNVYEGLLRVGGPDEGKVDNGCPREPVGASGQQLRV
VLKVLDPSHHDIALAFYETASLMSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWL
RRQRGQVPMTWKMAVAQQLASALSYLEDKNLVHGNVCGRNILLARLGLEEGTSPFIKLSD
PGVGQGALSREERVERIPWTAPECLSGGTSSLGTATDMWGFGATLLEICFDGEAPLQGRG
PSEKERFYTKKHQLPEPSCPELATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGISA
VNSDSPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQ
LRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQ
LLLFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVRE
DGDSPVFWYAPECLKECKFYYASDVWSFGVTLYELLTYCDSNQSPHTKFTELIGHTQGQM
TVLRLTELLERGERLPRPDRCPCEIYHLMKSCWETEASFRPTFQNLVPILKTAQEKYQGR
VPSVFSVC
NT seq
3627 nt
NT seq
+upstream
nt +downstream
nt
atggtggggagcatgcctctgtgtgggcggagagccaccttgaaagacagcaaggcagat
ggcacagattttcagcccctggtgcccacaggacgcttgatggtgctgctgcactggcct
ggacctaagggtggggagccctgggtcaccttcagccagacatctctgactgcagaggag
gtctgcatccacatcgcacacaaagtcggcatcactccaccctgcttgaatctcttcgca
ctctacaatgcacaggccaacgtctggctgcccccaaaccatattctggatgcatcccaa
gatgtgagcctctattttcgagtgaggttttacttccggaactggcacggcatgcatccc
caggagccagctgtataccgatgtggtttcccaggggcagagaattcctctgaccgggca
gaacaaggtgtacagctcttggactctgcctcatttgaatacctttttgagcaggtgtgg
tttgttggcaatagagcaaaaagctcccacacctctttttctatccatccctcttcccct
cagggaaaacatgacttcatgaatgacgtggtgtctctgcgggacctgtctagtgaggag
gagattcaccactttaagaatgaaagcttaggcatggccttcctgcacctgtgccacctt
gctctcagccgcggcgtccccctggaggagatggccagagagatcagcttcgagaactgc
atccctcattccttccgacagcatatccgacagcacaatgtgctcacgcgcctgcgtctc
cgcagagtcttccgccgcttcctacgggccttccggcctggccacctctcccaacaggtt
gtgatggttaagtacttggccaccctggagcggctggctcctcgctttggctcagagcgc
atacctgtgtgtcatctggaggtcctggcacagcctgagagggacccctgctacatccag
aacagtgggcagaccactggggacccaggcccagagctgccttccgggcctcccacccac
gaggtactggtgacaggcaccggaggtatccagtggcatccactacagacccaggaatct
gagagaagtaacagcagagaaaatccccaaggcagcagccggtctgggaagaaacccaaa
ggccctgaggctggagagcgcctggcagagagtcctcaggaaccaccttggacctacttc
tgtgacttccaggacatttcccatgtggtgctaaaggagcgtcgcgtgcacatccacctc
caagacaacaagtgcttgttgctgtgcctctgttcccaggctgaggccctgtcctttgtg
gccctggtcgatggctatttccgcttgactgctgactccagccactacctgtgccatgag
gtggcccccccgaggctggtgactagcatccagaacggcatccatggacccctgatggat
ccctttgtacaggccaagctgtggccagaggatggcctctacctgattcagtggagcacc
agccacctgcaccgcctgatccttactgtggcccatcgaaacccggctcccggtaatggc
cctaggggcctgcgcctgcgcaagttccccatcacacagcagcccggagcctttgtactg
gacggctggggccgctcctttgacagcttgggggaccttcgcctcgccttgcagggctgc
tcattgcgggctggtgatgactgtttccccctgcaccactgctgcctgccccggccaaga
gaaatctccaacctcgtcatcatgcggggatccagggcccacacccggcctctcaacctc
agtcagctcagcttccacagggttcaccaagatgaaatcacccagctgtcccacttgggc
cagggcacaaggaccaatgtgtatgagggccttctaagagtgggaggccccgacgagggc
aaagtggacaatggatgtccccgcgagcctgtcggggccagtgggcagcagcttcgagtg
gtgctcaaagttctcgaccccagtcaccatgatattgccttggccttctatgagactgct
agcctcatgagccaggtgtcacacatgcacctggctttcctgcatggtgtttgcgtgcgt
ggctcagagaacatcattgtgacagaattcgtagaacatggtccgttggatgtgtggtta
cggcgacagaggggccaagtgcccatgacctggaagatggccgtggctcagcagctggcc
agcgccctcagctacctggaggacaagaatctggttcacgggaacgtatgtggccggaac
atcctgctggctcgcctggggctggaggagggtaccagccccttcatcaagctaagtgat
cctggtgtgggccaaggtgccctctccagggaagagcgagtggagcgcatcccctggaca
gctccggagtgcctgtccggagggaccagtagcttgggcactgccacggacatgtggggc
tttggtgccacccttcttgagatctgctttgatggggaggcacccctgcagggtcgtggt
ccctctgagaaagaacggttctacacaaagaaacatcagctgcctgaaccctcatgccca
gagctggccacactcactcgccagtgcctgacctatgaaccagcacagcggccatccttc
cgcaccattttgcgggacctcacaagactacagccacagaatctggtcggcatttcggct
gtgaactcagactcaccagcatcagaccccactgttttccacaagcgttatttgaaaaag
atccgggatttgggcgagggtcactttggcaaggtcagcctgtactgctacgacccaacc
aatgacggcactggggagatggtggccgtgaaggccctgaaggaggggtgcggtccccag
ctccgctcaggctggcagcgggagattgagatcctgcggacactgtaccacgaacatatt
gtcaagtataaaggctgctgtgaggaccaaggagagaagtctgtacagctggtcatggag
tacgtccctctgggcagcctccgagactacctgccaaggcacagcgtagggctggcacag
ctcctgctgtttgcccagcagatctgcgagggcatggcctacctgcatgctcagcactac
attcaccgagacctcgccgcgcgcaacgtgctgctggacaacgataggctggtcaagatt
ggagactttggcctagccaaggctgtgcctgaaggccacgagtactaccgagtgcgcgag
gacggggacagcccagtgttctggtatgccccagaatgcctgaaggagtgcaaattttac
tatgcatctgatgtctggtccttcggggtaaccctgtatgagctgttgacatactgtgac
tctaaccagagcccccacacgaaattcaccgagctcattggccatacccagggccagatg
accgtgctgaggctcacagagctgctggaacgaggagagaggctgcctcggcctgacagg
tgtccctgtgagatctatcacctcatgaagagctgctgggagacagaggcctccttccgg
cccaccttccagaatcttgtgcccatcctcaagacggcacaggagaagtaccaaggccgg
gtgccttccgtgttcagcgtgtgctga
DBGET
integrated database retrieval system
