Mus pahari (shrew mouse): 110331271 Help Entry 110331271         CDS       T05929                                  Symbol Obscn Name (RefSeq) LOW QUALITY PROTEIN: obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism mpah  Mus pahari (shrew mouse) Pathway mpah04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mpah00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     110331271 (Obscn)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpah01001]     110331271 (Obscn)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mpah04131]     110331271 (Obscn) Enzymes [BR:mpah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      110331271 (Obscn) Protein kinases [BR:mpah01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    110331271 (Obscn) Membrane trafficking [BR:mpah04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     110331271 (Obscn) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 Ig_4 PK_Tyr_Ser-Thr SOS1_NGEF_PH C2-set_2 fn3 RhoGEF PH FN3_DSCAM-DSCAML_C ABC1 IQ Pkinase_fungal Motif Other DBs NCBI-GeneID:  110331271 NCBI-ProteinID:  XP_021067400 Ensembl:  MGP_PahariEiJ_G0017555 LinkDB All DBs Position 14:complement(27012590..27152068) Genome browser AA seq 8987 aa AA seqDB search MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQD GDVYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRV REGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEDLGEASALRIRSARPRDGGT YEVRAENPLGSASAAAALVVDLDAEVAGPPGTSTATLLAHLQQRREAMRAEGVPPSPPGA GTRTCTVTEGKHARLSCFVTGEPKPQTVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCK QSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVQEKESATFQCEVAQAATE AAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGNL TRKLPRKTAVRTGDTAIFWVELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQC TLEDMGEVAFVSGGCRTTTQFCVSAPRRPPLYPPADPVVKAKTESSVTLSWSPPPRGDRP VTIDGYVVEKRKLGAYAWSRCHEAGWVATTEFTITGVAEEGDFQFRVSAINHFGQSPYLE FPGTMHLVPMLAVKTPLKAVEAVEGGEVTFSVDLTVASSGEWFLDGEALKASSIYVIRCD RTRHMLTIREVPARLHGAQLKFVANGIETSIRMVVRAALGLPSDKLPATAAREVLAQLHE EARLLAELSDQAAAVTWLKDGRELSLGPKYEMQMSAGRRALLVRDVAQDDAGLYECVSRG SRTAYQLLVQEPKPVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSS KVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFCLDVAEPKPVFAKGQQAHSEVKA EAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGYSRRLVVQQAGKADAGEYSC EAGGQKLSFRLDVAEPKLVFAKEQQACSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKL SSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFCLDVAEPKPVFAKEQQAHS EVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAG EYSCEARGQKLSFRLDVIEPKLVFAKDQQAHSEVKAEAGTSATLSCEVAQAQTEVTWFKD GKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFCLDVAEPKPVFAKGQ QARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSSCLISSXFGL PGLDSVSDYICLSPEPKPVFAKEQQARSEVKAEAGDSATLSCEVAQAQTEVTWFKDGKKL SSSSKVRVEASGCSRRLVVQQAGKXDAGEYSCEAGGQKLSFRLDVADAGEYSCEAGGQKL SFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVR VEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAG NSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAG GQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSS SKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVAEPKLVFAKEQQARSEVK AEAGNSATLSCXXXXXXXXXXWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGQADAGEYS CEAGGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASTTLSCEVAQAQTEVTWFKDGKK LSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEAESHIPERPSRR EPLVVKEHETIVLTATIAAPSVAAVTWLKDGVEIRRSKRHEVTSLGDTHTLTVRGAQVLD SAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVTLVCELSPEQTEVVWRCGN TQLREGKRFQMTSEGSRRTLTVSGLREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGL SAMVAEEGQEATFQCVVSPSDAGVMWYKDGTQLQPSEKFVMVESGASRSLTILGLTLEDA GHITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEVKWTRNAA VLTPSENVEIRAEGVRHWLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQVRLVRGLQA VEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSALQPQDSGL VAFRAEGVHTSARLIVTELPVSFTRLLQDVVATQKEKVTLECELSRPVDVRWLKDGVELR AGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQGRSVQITKPLEDVEV MEKEGATFSCEVSHDEVPGLWFRESCKLRPSDNVRIRQEGRTYTLIFRRVLAEDAGEIKF VAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGGVELHPG PKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLKDMTVME PAPAWFECETSIPSVRPPKWLLGKTVLQAGANVGLEQDGTVHRLTLHKTCSTMTGPVHFT IGKSRSSAQLVVSDIPVALTRPLEPKAGREQQSVVLSCDFRPAPKAVQWYKDDTPLSPSE KFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVIQPLQDAEAMEE GRVCFSCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSVRQADTGTVCATSP KVSVSARLVVKAKPVVFLKALDDVSAEERGTLTLQCEVSDPEARVVWRKDGVELGPSDKY DFLHKAGARALTVHDLSHEDAGLYTCQVGSKETQSKVSVHDLHVGITKRLKTVEVLEGES CSFECVLSHESPSDPAVWTVGGKTVGGSGHFQAVRQGRKYTLTVKDAALSDAGEVVFSVL GLTSKASLIIRERPVDITKPLEDQRTTLGEDATLSCELSRAGTSVRWLKDGKAIRKSQKY DLLSEGTRAVLVVRKASLKDSGEYTCETEVSKSTAKLCVEEKANRFTEELTDLQVEEKGR AVFTCKTEHPASVVTWRKGLLELRTSGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQA RTQARLLVHGQRVRIIEDLEDTAVQEGSSAKFCCRISPADYGPVHWFLDKTPLHSNELNE ITVQPGGYHVLTLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGED LTLVCETTTVDSSVRWTKDGKTLKPSARCQLSREGCQAQLLITATTPQDGGRYKCEIGGA SSSSIVRVHALPVRFRESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSL RQEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTMVT LRCELTKEAPVEWKKGTETLRNGDKYTLKQDGAVCELQICSLLVADAGEYLCVCGQEKTS ATLTIKALPVHFVRRLRSKEATEGDTTTMQCELSKAAPVEWRKGTETLRDGDRYSLKQDG AVCELQIRSLTIADAGEYLCTCGQEKTSATLSIRALPAKFKDGLKNEEATEGTTATLSCE LSKAATVTWKKGPKTLRDGDKYGLRQDGAVCGLQIHGLTTADAGEYSCVCGQEKTSATLT VRGLPAKFIEDLRSQEATEGATAILRCELSKAAPVEWRKGSETLRDGGRYSLRQDGAVCE LQIRGLAVEDSGEFSCVCGQEKTSTTLSVKALPPRFIEDLRSQEATEGTVATLRCQMSKV APVEWRKGSETLRDGGRYSLRQDGALCELQIRGLAMEDSGEYSCVSGQEKTSATLSVKAL PPRFTEDLRSQEATEGTVATLRCQMSKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQIR GLAVEDSGEFSCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTVATLRCQMNKAAPVE WRKGSETLKDGGRYSLRQDGAVCELQIHGLAVEDAGQYSCMCGKEKTSAMLTVDALPTXF TEELKSKEFMEGCXTTLQCQLSRKASVEXKKGTETLRDIDGHKLQQKGAMCELQMHSLAM LGAGEHTCVCGGGEAKTTAMLTVRALPPKFTEGLKEEEATEGTMVTLRCQMSKEAAVEWR KGAKTLRDGGRYSLRQDGAVCELQIRDLAVEDAGEFSCVCGQEKTSATLSVKALPLRFIE DMRSQEATEDTMAILRCQMSKAAPVEWRKGSETLRDGGRYSLRQEGAVCELQIRGLAVED SGEYSCVCGQEKTSATLSVKALPPRFIEDLSSQEATEGTVATLRCQMSKAAPVEWRKGSE ILRDGGRYSPRQDGAVCELQIRDLAVEDAGEFSCVCGQEKTSAILSVKALPARFIEALRS QEATESSTITLRCELSKKAPVVWRKGSETLRNGARYSLRQDGAVCELEIHDLTVEDAGEY SCTCGQERTSATLSIMAPQVVFQKPLQNLQAEEGSMASLQCELSVPNTAVVWSKGGLELQ DDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTAAPVRFLRELQAQDV DEGATARLRCELSREAVSIEWRKGSLQIFPCAKYQMVQEGTTAELLVHGVEQEDAGEYTC DAGHKQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSEAEPGTPVQWLKEGVELH VGTKYEMRRQGAMCELLIHGLEAKDTGEYACLVGGQKTLASLRVKEPEVTIVRGLVDMEV QADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLGDGCTHVLQLKGVTLEDAGT VSFHVGGHSSSAQLTVRVPEVTVLEPLKDVQLSEGQDAHFRCRLSRASGQEARWALGGVP LQCNEMNDITVEQGTLYLLTLHKVTLEDAGTITLQVGSCSSEAQLKVTAKNTVLRGLENV DALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEMVYFENGLRHLLLLKNLKPQDS CRVTFLAGDVVTSAFLTVRGWRLEVLEPPHDASVKAGMQVCFTCILSEAVPVGEATWYIN GAAIQPDDADWTVTADGSHHALTLSNAQPQHAGEITFAARDAVASARLSVLALPDPPEDA EVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDGLVPG KTYRFRVAAVGPAGAGEPVHLPQMVKIAPAPAPAPAPAPAPATRQAVVGEDLCLELEVAA DAGEVVWHKGTERIQPGGHFEILSQGQRQMLVIKGFRTEDQGEYRCGPIQGLPSSGAATF NVVMTSGSGDEVPAQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDSRV QHLRQEAEETAPDLSEGYSTADELARTGEADLSHTSSDDESRAGTPSLVTYLKKAGGPGI SPLASKVSFLVTTSVKPQKQQEPVVPTCPPPGDLSAADLNDPSLDKAAVKIQAAFKGYKV RKEMKQQEGPVFSRTFGDTEAQVGDVLRLECVLATKADMRACWLKDGIELTDGRHYHIDQ LKDGTCSLLVTGLGPTDSGRYTCQVNTKFGRVSHSACVVVSGTESEAESSSGGELDDAFR RAARRLHRLFRTKSPAELSEEELFLSADEGPAEPEEPADWQTYREDENFVCIRFESLAEA RRAVTCFRDMFATMGIGVEISLGEQGPRGVEMRIGKVAPTVTPAVSLAKTPGLQTSDAAP VFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLII TAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADATETSSYFSAQGYLSSRE QEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIR MTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERL VPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASS SKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQERVKEALISSFLQ GTSHAVSAQMSESTGFADLVGQRKGESLVAEEAHSHLSLAEVGTEEFLQKLTSQITEMVS AKFSQAKLQVPGGDSDEESKTPSASPRHGRSRPSSSVQESSSESEDGDSRGEIFDIYVVT ADYLPLGAEQDAIILREGQYVEVLDSAHPLRWLVRTKPTKSSPSRQGWVSPAYLDKRLKL SPEWGPTEAPEFPGEAVSEDEYRTRLSSVIQELLSSEQAFVGELQFLESHHMKHLDRSPR VPAAVASQKTVIFRNVQDISHFHSSFLKELQGCGTDDDVAMCFIKNQEAFEKYLEFLVGR VQAESVVVSTPVQEFYKKYAEETLSAKDPTQPPPPPLQHYLEQPVERVQKYQALLKELIR NKARNRQNCALLEQAYAVVSALPQRAENKLHVSLMENYPGTLEALGEPIRQGHFIVWEGA PGARMPWKGHNRHVFLFRNHLVICKPRRDSRTDTFSYVFRNMMKLSSIDLNDQVEGDDRA FEVWHEREDSVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRSPEFEEELADCTAELG ETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCF AASAAGNASTLGKILVQVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGALL TLGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGELYMQSPALRARD QHHREQIVAAVEVTEQETKVPKKTVIIEETITTVVKSPRGRRQSPGKSPSRSPSRRSASP RRPGLLAPERLYPPGTSPSRRLEVEQGRKAPVPALYVTEAEVRTPASQSQPKWLEVEETI EVRVKKTGSRGASPVREMTSHGEGILFTLPGGIPGRDPNANNSNNKSVYQEARTWGPTAV HVGEPFVFQVDSVGNVDWVAASSEPEQVRASQKEEDTEREEGCSDGDENTFLMEEPQDAD SLQGRDPKILTHNGRVLTLADLEDYVPQEGETFGCGDPTPSTSDDPPCEVSVLQREIGEP MVGQPVLLNVGRPPGTGATPSFFRPGSQVHSPESVSFLLRGSPSQGQQQQQRQQHVRWKK EGDTSVEGSAHSTQDGVDQQAASVLWRLLGSEALGPSSGDLPNTRQSEPPAFQEAASQIP GAASGTPGELPEVSQPGTHKGLEQETTSSGSQGWTVPIRVEGTAWPGAGTGQLLLDVHSQ VIMETTQRTYVCQAPDTGVTRAPSMQVPIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKDS TQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDA EKQVYRRKLHSFYEVQEEIGRGVFGFVKRVQHKGNKMSCAAKFIPLRSKTRAQAYQERDI LATLGHPLVTGLLDQFETRKTLILILELCSSEELLDRLFKKGVVTEAEVKVYIQQLVEGL HYLHSHGILHLDIKPPNILMVHPAREDIKICDFGFAQKITPSEPQYSKYGSPEFVSPEII EQNPVSEGSDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAK DFIKATLQKTPRARPSTSQCLAHPWFLNSMPAEEAHFINTKQLKFLLARSRWQRSLMSYK SILVMRSIPELLQGPPDSPSLGVARHLRGEASGSSSSSSSSDNELAPFARAKSLPPSPVT HSPLLHPRGFLRPSASLPEETEASMPTADVAVPASPQSAGPPASPGCVPRHSVISSLFYQ QAGEGAERGSKTSGAKRHLARRRHLLKGGYIARALPGLREPLMEYSLLEEEAAREEQASL MTKTPSFETALRLPSSNVREVPGRSRSLDNPPVTTGPSPEACKEQFLFPPSSGLTHETTA KDGGHKEVFLQESVSFPPMSGDLRPGKQEGSSQDSCRGKPTSSCHSELGSGSQEGCGPPS SQSLGSLPPQSLKKELSTSCGPHFSEQPQVAPFPTQVSPLLGSEKEPQDGSLSEGPVPVP SSSPGSASQVDASLDTEGLSEAGDTCDITPPPQRPQEQATTRKFSLESRGGYAGVAGYGT FAFGGDAGGMLGQGPLWARMAWAVSQSSEEQDEAVTESPQPLESSGPITEASGVPLRTSP SLTPWEEVEQVSLVQIRDLSGDAEAADTISLDISEVDPAYLNLSDLYDIKYLPFEFMIFR RVPKPVEQPESPDSETEAGQGLADFLEEAAWPWPGELGLRAGLEITEEPEEPGDLEALLG EAAVGRKRKWSPSRGLFQFPGRCLSGEEPAELGLRQRVKASMAHISRILKGKPEGPEREG PPRKKAGLGSFRLSGLKGRDQAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDG VLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSS PRPEVGELYTDAVLLVWKPVESCGPVTYIVQCCIEGGSWTTLASDISDCCCLTGKLPRGG VYTFRTACVSKAGMGPYSSPSEQVLLGGPNHLASEEESSRGRPAQLLPSTKTFAFQMQIR RGRFSVVRQCREKASGRALAAKIIPYQPEDKTAVLREYEALKRLHHPHLAQLHAAYLSPR HLVLILELCSGPELLPSLAERDSYSESDVKDYLWQMLSATQYLHAQHILHLDLRSENMMV TEYNLLKVIDLGNAQSLSQEKVPAPENFKDYLETMELLEGQGAVPQTDIWAIGVTAFIML SGEYPESSEGTRDLQKGLRKGLIRLSRCYAGLSGGAVAFLQSSLCAQPWGRPCASTCLQC GWLTEEGPTGSRPTPVTFPTVRLRAFVREREKRRALLYKKHNLAQVR NT seq 26964 nt NT seq  +upstreamnt  +downstreamnt atggaccactccttcagcggagcaccccgcttcctgacgcggccaaaggcctttgtagta tctgttggcaaggatgccacgctgagctgccagatcgtgggcaaccccacgccacacgtg agctgggagaaggaccggcagccagtggaggcaggagcgcgcttccgcctggcccaggac ggggatgtgtaccgcctcaccatcctcgatctggcgctaggtgacagcgggcagtatgtg tgtcgcgcgaggaacgccataggggaggccttcgccgccgtcggcctgcgagtggactcg gagggcacgtgtgccgagcaggcgccccactttctgctgcggcccacgtccattcgcgtg cgcgagggcgcagacgccaccttccgatgtcgcgttggaggctcaccacaacctgctgtg agctggtccaaagatgggcggcgcctgggcccacccgatgccccccatgtgcgcgtggaa gatctcggcgaggcgagcgcgcttcgtatccggtcggcaaggcctcgtgatggtggcacc tatgaagtccgagcagagaatccgctgggctccgccagcgctgccgctgctctggtggtg gacttggacgccgaggttgccggaccacccggcacctccaccgccacgctcctggcgcat ctgcagcagcggcgagaggccatgcgcgcagagggcgtccccccttctccacccggcgct ggcacgcgcacctgcacggtgaccgaaggcaaacacgcgcgcctcagctgctttgtgacc ggcgagcctaagccccagacagtgtggaagaaggacgggcagctggtgaccgagggccgg cgacacgtagtgtatgaggacgagcaagagaacttcgtccttaagattcttttctgcaag cagtccgaccgcggcctttacacctgcacagcatccaacctcgtgggccagacctacagc tcggtgctggtggtcgtgagagagccgacggtgcccttcaagaagcggctgcaggacctg gaggtgcaagagaaagagtctgccacattccagtgcgaggtggctcaggcagccaccgag gcggcgtggttcaaggaggagacccggctatgggccagcgccaagtacgacatcgaggag gagggcaccgagcgccggctgaccgtgcgcaacgtctcggcagacgacgatgcggtgtac atctgtgagaccacagagggcagccgcacggttgcagagctctctgttcaaggaaacttg accagaaagctgcctcggaagacagcggtgcgcactggagacacagccatcttttgggtg gagctggctgtccccgaaggccctgtccggtggctacggaatcaggaggagatggtggca gggggccgggttgccatcactgcagaaggcacgtgccacacgctgaccatcttccagtgc accttggaggacatgggagaggtggcctttgtgtctggtggctgccggacgaccacccag ttctgtgtatcagcacccaggaggccacccctgtaccctcctgctgaccctgttgtaaag gccaagacagagagttctgtgaccctcagctggtccccaccaccccgtggggaccgccct gtcactattgatggctatgtggtggagaagaggaagctgggtgcctatgcctggagcagg tgtcacgaagctggatgggtggccacgactgagttcaccatcactggtgtggccgaggaa ggggacttccagttccgagtgtcagccatcaatcactttggccagagtccttaccttgag tttccagggaccatgcacttggtccccatgctggccgtaaagacacctctgaaggcggtg gaggcagtggagggtggtgaagtcactttctccgtggacctcacggtggcctcttcgggc gaatggttcctggatggggaggccttgaaagcgagcagtatatatgtgatccgttgtgac cgcacccggcatatgctcaccatcagagaggtgcccgccagattgcacggggcacagctg aagtttgtggctaatggcattgaaactagcatccgaatggtggtccgagcggctctgggg ctgcccagtgataagcttcctgccacggctgcgcgggaggtgctggcccagttgcacgag gaggcacggctgctggctgagctgtcggaccaggctgctgctgtgacttggctgaaggac ggtcgtgagctgtccctggggcccaagtatgagatgcagatgtcagctgggaggcgagca ctgctggtgcgggacgtggcacaggatgatgctggcctctatgagtgtgtcagtcgtggg agccgaactgcctaccagctgttggtgcaagagcccaagccggtgtttgccaaggggcag caggcacacagcgaggtgaaggcagaggcgggggccagtgccacactgagctgcgaggtg gcccaggcccagactgaggtgacctggttcaaggatgggaagaagctgagctccagctcg aaggtgcgcgtggaggcctcgggctgctccaggaggctggtggtgcagcaggcgggcaaa gcggatgctggggagtacagctgcgaggccgggggtcagaagctctccttctgcctggat gtggcagagcccaagccggtgtttgccaaggggcagcaggcacacagcgaggtgaaggca gaggcgggggccagcgccacactgagctgcgaggtggcccaggcncagactgaggtgacc tggttcaaggatgggaagaagctgagctccagctcgaaggtgcgcgtggaggcctcgggc tactccaggaggctggtggtgcagcaggcaggcaaggcggatgctggggagtacagctgc gaggccgggggtcagaagctctccttccgcctggacgtggcagagcccaagctggtgttt gccaaggagcagcaggcatgcagtgaggtgaaggcagaggcgggggccagcgccacactg agctgcgaggtggcccaggcccagactgaggtgacctggttcaaggatgggaagaagctg agctccagctcgaaggtgcgcgtggaggcctcaggctgctccaggaggctggtggtgcag caggcgggcaaggcggatgctggggagtacagctgcgaggccgggggtcagaagctctcc ttctgcctggacgtggcagagcccaagccggtgtttgccaaggagcagcaggcacacagt gaggtgaaggcagaggcgggggccagcgccacactgagctgcgaagtggcccaggctcag actgaggtgacctggttcaaggacgggaagaagctgagctccagctcgaaggtgcgcgtg gaggcctcgggctgctccaggaggctggtggtgcagcaggcgggcaaggcggatgctggg gagtacagctgcgaggccagggggcagaagctctccttccgcctggacgtcatagagccc aaactggtgtttgccaaggatcagcaggcacacagtgaggtgaaggcagaggcggggacc agtgccacactgagctgtgaggtggcccaggctcagactgaggtgacctggttcaaggat gggaagaagctgagctccagctcgaaggtgcgcgtggaggcttcaggctgctccaggagg ctggtggtgcagcaggcgggcaaggcggatgctggggagtacagctgcgaggccgggggg cagaagctctccttctgcctggacgtggcagagcccaagccggtgtttgccaaggggcag caggcacgcagcgaggtgaaggcagaggcggggaacagcgccacactgagctgcgaggtg gcccaggcccagactgaggtgacctggttcaaggatgggaagaagctgagctccagctcg aaggtgcgcgtggaggcctcnggctgctccagctgcttgatttcctcctgatttggtctt cctggcctagacagtgtctctgattacatctgtctgtccccagagcccaagccggtgttt gccaaggagcagcaggcacgcagcgaggtgaaggcagaggcgggggacagcgccacactg agctgcgaggtggcccaggcccagactgaggtgacctggttcaaggatgggaagaagctg agctccagctcgaaggtgcgcgtggaggcctcnggctgctccaggaggctggtggtgcag caggcgggcaaggnggatgctggggagtacagctgcgaggccgggggacagaagctctcc ttccgcctggacgtggcagatgctggggagtacagctgcgaggccggggggcagaagctc tccttccgcctggacgtggcagagcccaagctggtgtttgccaaggagcagcaggcacgc agcgaggtgaaggcagaggcaggggccagcgccacactgagctgcgaggtggcccaggcc cagactgaggtgacctggttcaaggacgggaagaagctgagctccagctcgaaggtgcgc gtggaggcctcgggctgctccaggaggctggtggtgcagcaggcgggcaaggcggatgct ggggagtacagctgtgaggccgggggccagaagctctccttccacctggacgtcacagag cccaagctggtgtttgccaaggagcagcaggcacacagcgaggtgaaggcagaggcaggg aacagcgccacactgagctgcgaggtggcccaggcccagactgaggtgacctggttcaag gatggaaagaagctgagctccagctcgaaggtgcgcgtggaggcctcgggctgctccagg aggctggtggtgcagcaggcgggcaaggcggatgctggggagtacagctgcgaggccggg ggacagaagctctccttccgcctggacgtggcagagcccaagctggtgtttgccaaggag cagcaggcacgcagcgaggtgaaggcagaggcggggaacagcgccacactgagctgcgag gtggcccaggctcagactgaggtgacctggttcaaggacgggaagaagctgagctccagc tcgaaggtgcgcgtggaggcctcgggctgctccaggaggctggtggtgcagcaggcgggc aaggcggatgctggggagtacagctgcgaggccgggggacagaagctctccttccacctg gacgtggcagagcccaagctggtgtttgccaaggagcagcaggcacgcagcgaggtgaag gcagaggcggggaacagcgccacactgagctgcnngnnnnnnnnnnnnnnnnnnnnnnnn ncctggttcaaggacgggaagaagctgagctccagctcgaaggtgcgcgtggaggcctcg ggctgctccaggaggctggtggtgcagcaggcgggccaggcggatgctggggagtacagc tgcgaggccgggggacagaagctctccttccgcctggacgtggcagagcccaagctggtg tttgccaaggagcagcaggcacgcagcgaggtgaaggcagaggcgggggccagcaccaca ctgagctgcgaggtggcccaggctcagactgaggtgacctggttcaaggacgggaagaag ctgagctccagctcgaaggtgcgcgtggaggcctcgggctgctccaggaggctggtggtg cagcaggcgggcaaggcggatgctggggagtacagctgcgaggccgggggtcagaagctc tccttccgcctggacgtggcagaggccgaatcccatattccggagagacccagccgcagg gagcctctggttgtcaaggaacatgagaccattgtcctgaccgccacaatagctgcaccc tctgtggctgctgtgacttggctcaaagatggagtggagatccgccgcagtaagcggcac gaggtcaccagtctgggtgatacccatactctgaccgtgagaggcgcacaggtcctggac agtgccatctacagctgccgtgtcggcaaggaaggtcaggacttcccggtgcaagtagaa gaggtggccgccaagttctccaaacccctggagcccgtcgaaggggaactgggtggcacc gtgacgctggtctgtgagctgagcccggagcagaccgaggttgtgtggcgctgtgggaac acacagctgcgggagggcaagcgcttccagatgacatcggaggggtctcggcgcacgctg accgtgtctggcctgcgagaggatgacgcagaggagtatgtgtgtgagagtcgggatgac cgcaccagcgcacggctcactgttaaagttccccgagtggtcaagtttacatctggattg agtgccatggtcgcagaggagggccaagaggccacctttcagtgtgtcgtgtcccccagc gatgcaggggtcatgtggtacaaggacgggacgcagctgcagcctagtgagaagtttgtt atggtagagagcggggccagccgcagcttgaccatcttgggcctgaccctggaagatgcc ggtcacatcacagtggaggctgagggggcctcatcttctgctgccctccgggtccgagag gcaccggtcctcttcaaaaagaagcttgagccacagacggtggaggagaggacctctgtg acactggaggtggagctgacgcggccctggcccgaggtgaagtggacacggaatgctgct gtcctgacacccagcgagaatgtggagatccgcgctgaaggtgtccggcactggctggtg ctgcgcagcgtgggctttgctgaccgtggcttctttggctgtgagacaccagatgacaag actcaggccaagctcaatgtagaaatgcggcaggtccggctggttcgcggtttgcaggcg gtggaagctaaggaacagggcacggcctccatggatgtggagttgtcccatgccgaggtg gagggcagctggacccgagatggcctgcgacttcagcctggacccaaatgccacctggcc gtacaaggccctgtccacatcctcacactctcggcgctgcagccgcaggacagcgggctg gtggccttcagggccgagggtgtgcacacatctgcgcggctcatagtcactgagttgccc gtgagcttcactaggctactacaggatgtggtggccacacagaaggagaaggtcaccctg gagtgtgagctgtcgcggcctgtggatgtgcgctggctgaaggatggtgtggagcttcgg gcaggcaaggccataggcatagtggcccagggaacctgcaggagtctcgttatctaccgg tgtgagactggggaccagggtgtctatgtatgtgatgctcttgatgcccagacctctgcc tctctgcgggtgcaaggtcgcagtgttcagattacgaagccgctagaggatgtggaggtg atggagaaggagggtgccacattctcctgtgaggtgtcccatgacgaggttcctggcctc tggttccgagaatcctgtaagctacggcccagtgacaacgtacgcatccggcaggaaggg aggacgtacactcttatcttccggagggtactggcagaggacgcgggggagatcaagttt gtagctgagaatgcagaatcaagagctcacctccgagtgaaagaactgcctgtgaccctc ctgcgcccactgcgggacaagattgccatggaaaaacaccgtggagtactggagtgccag gtgtcccgggctagtgcccaggtgcggtggttcaagggcggagtggagctgcaccccggg cccaagtacgaggtggtcagtgacggcctttaccgcaagctggtcatcaatgacgtgcag cctgaggatgaagatacgtacacctgtgacgctggcgacgtcaagaccagtgcccagttc tttgtggaagagcaatccatcactatcgtgcgggggctgaaggacatgacagtgatggag cctgcccctgcctggtttgaatgtgagacctccattccttctgtgaggccacccaagtgg ctccttggtaagactgtgctccaggcaggggcgaacgtgggactggagcaagacggcacc gtgcaccggctgacactgcacaagacctgctctaccatgaccgggcctgtccatttcacc attggcaagtcccgctcctctgcccagcttgttgtttcagacattcctgtggcactgaca cggcctctagagcccaaagcagggcgtgagcagcagtcagtagtcctgtcctgtgacttc aggccagcccccaaggctgtgcagtggtacaaggacgacacacccctgtccccatcagaa aagttcaagatggcgctggagggccagatggcagagctgcgcatactccggctcacacca gctgatgctggggtctaccggtgccaggcgggtagcgcccagagcagtgccgaggttact gtggaagctcgggaggtgacagtgattcagccactgcaggatgcagaagccatggaggaa ggccgggtctgcttctcctgcgagctgtcccataaggacgaggatatcgaatggtcactc aatggtacacccctgtacaatgacagcttccatgagatcagccatgagggctgtctccac acactggtactgaagagtgtccggcaggctgacacaggcaccgtgtgcgccacgtccccc aaggtgtccgtttctgcccggctggtggttaaagccaagccagtggtgttcctgaaagca ctggatgacgtatctgcagaagagcgtggcacgctgaccctgcagtgtgaggtctccgac cccgaggcacgcgtggtttggcgcaaagacggtgtggagcttggtcccagcgacaagtat gatttcctacataaggcaggtgcccgggcccttacggtccatgacctgagccatgaggat gctggactgtacacctgccaggtgggcagtaaggagacccagtccaaggtcagcgtgcat gatcttcatgtgggcatcaccaagaggttaaagacggtggaggtgctggagggagagagc tgcagctttgagtgtgtcctttcccacgagagtcccagtgacccagccgtgtggacggtc ggcgggaagacagtgggtggttctggccactttcaggccgttcggcagggccgcaaatac accctgacagtcaaagatgctgcgctcagtgatgcaggagaggtggtcttctcggtgctg ggcctcacatccaaggcctcgctcatcatcagagagaggccagtggacatcacgaagccc ctggaggaccagcggacgacgcttggggaagatgctacgctaagctgtgagctgtcgagg gcaggcacctctgtgcgctggctgaaagacgggaaggccatcaggaagagccagaagtat gacctgctcagtgaaggcacgcgggctgtgttggttgtccgcaaagcctcgctcaaggat tctggggaatacacctgtgagacagaagtttccaaaagcactgccaagctctgtgtggaa gaaaaggcaaaccggttcacggaggagctgactgacctgcaggtggaagagaagggcaga gctgtgttcacgtgcaagaccgagcacccagcatctgtcgtgacctggcgcaaaggcctc ctggagctgcgcacctcagggaagcatgtccccagtcaggagggcttgaccctgaagctc accatcaatgccctggagaggacagacagtgacacttacacctgtgacatcggccaagcc cggacccaggcccggctcctcgtccacggccagagagtgcgcattattgaggacctagag gacacggctgtccaggagggctcctctgctaagttttgctgccgcatctcccctgctgac tatggccctgtgcactggttcctggataagacccccttgcacagcaacgagctgaacgaa atcactgtccagcctggaggctaccacgtgctcaccctacggcagctggcgctcaaggat tcaggcactgtctacttcgaggcgggtgaccagcggacctcagctgccctgcgggtgact gagaagccgagcatcttctctcggccactcacagacgtcacagtcacagaaggcgaggac ctgactcttgtctgtgaaaccaccaccgtggatagctctgtgcgctggaccaaagatggg aagacactgaagccctctgcacgatgccagctgagccgtgaaggctgtcaggcccagctg ctcatcactgccaccaccccacaagatggcgggcggtacaaatgtgagattggcggagcc tccagcagctccattgttagggtccatgctctgccagtgcggttcagggagtccctgaag gacgtggaggtgccagagggcaaggctgccacactacgctgtgtgctgtcatccgtggct gcacctgtggagtggcgtcatggagatgacgtcctgaaatccagcaacaagtatagcctg cgccaagagggtgctgtgctggaactggtcatccgagacctgcagccccaggacagtggg caatactcatgctcctttggggaccagacaacttcagccacactcacagtgaaaacctcc tctgcccagttcgtagggaaactgagaaacaaggaggccacagaagggaccatggtcaca cttcggtgtgagctgaccaaagaggcccccgtggaatggaagaagggaacagagaccctg agaaatggggacaaatacactctgaagcaggatggcgctgtgtgtgagctgcagatctgt agtctgctcgtggcagatgcaggggagtacttgtgtgtatgcgggcaggagaagacttcg gccacgctgactatcaaggctctgcctgtccactttgtcagaaggctcaggagcaaggag gccacagaaggggacacgaccaccatgcagtgtgaactgagcaaggctgcccctgtggag tggagaaagggaacagagaccctgcgagatggggacagatacagcttgaagcaggatggg gccgtgtgtgagctgcagatccgcagcctgaccatagcagatgctggcgagtacttgtgc acatgtggacaggaaaagacctcagccacactgagcatcagggcccttccagctaagttc aaagacggtctgaagaacgaagaggccacagaaggcaccacggcgacactgagctgtgag ctgagcaaggcagctacggtgacgtggaagaaaggaccgaagaccttgcgagacggagac aaatatggcctgaggcaggacggagctgtgtgtgggctgcagatccacggcctgaccacg gctgatgctggggagtactcctgtgtgtgtggacaggagaagacgtcagccacgctgact gtcaggggcttgcctgccaaatttatagaagatctgagaagccaagaagccacagaaggg gccacagcaatcttaagatgtgagctgagcaaggctgctcctgtggaatggaggaaaggg tctgagaccctgagagatgggggcagatacagcctgaggcaggacggggccgtgtgtgag ctgcagatccgaggcctggccgtggaagattctggggagttctcatgtgtgtgtgggcag gagaagacttcaaccacactcagtgtcaaggccctgcctcccagattcatagaagacctg agaagccaagaggccacagaaggcaccgtggccactctgaggtgccagatgagcaaggtt gcccctgtagagtggaggaaggggtctgagaccctgagagatgggggcagatacagcctg aggcaggatggggctctgtgtgagctgcagatccgaggcctggccatggaagattctggg gagtactcatgtgtgagtggacaggagaagacgtcagccacactgagtgtcaaggccctg ccccccagattcacagaagacttgagaagccaagaggccacagaaggcaccgtggccact ctgaggtgccagatgagcaaggctgcccctgtggagtggaggaaggggtctgagaccctg agagatgggggcagatacagcctgaggcaggatggggctgtgtgtgagctgcagatccga ggcctggctgtggaagattctggggagttctcatgtgtgtgtgggcaggagaagacttca gccacactcagtgtcaaggccctgccccccagattcatagaagacttgagaagccaagag gccacggaaggcactgtagccactctgaggtgccagatgaacaaggctgcccctgtggag tggaggaaggggtcagagaccctgaaagatgggggaagatacagcctgaggcaggatggg gctgtgtgtgagctgcagatccatggcctggctgtggaagacgctggccagtactcgtgc atgtgtgggaaggagaagacgtcagccatgctgactgtagatgccttgcccacatgattc acagaagagctgaagtccaaggagttcatggaagggtgtngcaccactctgcaatgtcag ctcagcagaaaggcctctgtggaatgaaagaagggaaccgagactcttagggacatagac ggacacaagctgcagcaaaagggggccatgtgtgagctgcagatgcacagcctggccatg ttaggtgctggagaacacacgtgtgtgtgtggggggggggaagcaaagacaacagccatg ctgactgtcagggcactgccccccaagttcacagagggtctgaaggaggaagaggccaca gaagggaccatggtgacactgaggtgccagatgagcaaagaagccgcagtggagtggagg aagggagcaaagactctcagagatgggggcagatacagcctgaggcaggatggggctgtg tgtgagctgcagatccgtgacctggctgtggaagacgctggggagttctcatgtgtgtgt gggcaggagaagacgtcagccacactgagtgtcaaggccctgcccctcagattcatagaa gacatgagaagccaagaggccacagaagacaccatggccattttgaggtgccagatgagc aaggctgcccctgtggaatggaggaaggggtctgagaccctgagagacgggggcagatac agcctgaggcaggaaggggctgtgtgtgagctgcagatccgtggcctggctgtggaagat tctggggagtactcatgtgtgtgtgggcaggagaagacttcagccacactcagtgtcaag gccctgccccccagattcatagaagatttgagcagccaggaggccacggaaggcactgtg gctactctgaggtgccagatgagcaaggctgcccctgtggagtggaggaaggggtctgag atcctgagagatgggggcagatacagcccgaggcaggatggggccgtgtgtgagctgcag atccgtgacctggctgtggaagatgctggggagttctcatgtgtgtgtgggcaggagaag acatcagccatactgagtgtcaaggccttgccagctagattcatagaagccttgagaagc caagaggccacggaaagttcaacgatcacattgcggtgtgagctaagcaagaaggcccct gtggtgtggaggaaagggtccgagaccctaagaaatggggccagatacagcctgaggcag gatggggctgtgtgtgagctggagatccatgacctgactgtggaagatgctggcgagtac tcatgcacatgtgggcaggagagaacctcagccacactgagcattatggctccacaggtg gtattccagaagccactgcagaatctgcaagcagaagaaggctccatggccagtctgcag tgtgagctgtcagtccccaacactgctgtggtctggagcaagggtggcctggagctgcag gatgacacgcgccgagaggcacggcagcaggggtgtgtggcagagctgttgcttagggac ctgcgtcgtgaggatgcgggcgagtacagttgcacctgtggctctcagaccacaagcgcc acgctcatggtcacagctgctcctgtgcggttccttcgggagctgcaggcccaggatgta gatgagggggccaccgcacgcctgcgctgtgagctgagccgggaggctgtgagcatagag tggcgcaagggctccttgcagatttttccttgtgctaagtaccagatggtgcaggagggc acaactgcggagctgctggtccatggggtggagcaggaggatgcaggtgaatacacctgt gatgcaggccacaagcagagcatcgccaggctctctgtccgagcccccaagcccaagttc aagaccgacctgcaaagcacagagcaggaagcaggtggcacggcacggctgtgttgtcaa ctgagcgaagctgagccagggactccagtgcagtggctcaaggagggagtggagctgcac gtcggcaccaagtatgagatgcggcgccaaggggctatgtgtgagctgctgatccatggg ctagaggccaaggacaccggtgaatatgcctgcctggtgggtggccagaagaccttggcc tcccttagagtcaaagagcctgaggtgaccatcgtgcggggactcgtggacatggaggtg caggccgatgaggacgtggagttcacttgcaaggtgtcacaggcaggagccacagacgtg cagtggcacctccaaggtctgccactgcagagcaacgaagtgacagaggtggctgtcctc ggagacggctgtacccacgtgctccagttgaagggtgtgacactggaggatgctggcact gtctccttccacgtgggcggccattcatcttctgctcagctcacagtccgagtccccgag gtgaccgttctggagcccctgaaggatgtgcagctcagcgagggccaggatgcccacttc cggtgccgactgtccagggcctcgggccaggaggctcgctgggctttgggaggggttccc ttgcagtgcaacgagatgaacgacatcactgtggagcagggcacactctacctgctcact ctgcacaaggtgactctcgaggatgctggaaccatcactctccaagtgggctcatgctcc tcagaggcccagctgaaggtcacagccaagaacacggtgttgcgtggcctggagaacgta gatgcattggagggcggcgaggctctgttcgagtgccagctgtcccagcctgaagtggcc gcccacacctggctgctggacgatgagcctgtgcacacgtcggagaaggtggagatggtc tactttgagaacggactgcggcacctgcttctgctcaaaaacctgaagccacaggacagt tgccgagtgaccttcctggcaggggatgtggtcacgtccgcattccttactgtgagaggc tggcgcttggaggtcctagagcccccacacgatgcatctgtgaaagcgggtatgcaggtc tgcttcacgtgcatactaagtgaggcggtgcctgtgggcgaggctacttggtacatcaac ggggctgccatccaacctgatgacgccgactggacagtcactgcagatggaagccaccat gccctgacgctgagcaacgcccagccccaacacgcaggagagatcacatttgcagcacgg gatgctgtggcctctgcacgcctctctgtgttggctcttcccgacccccctgaagatgct gaagtggtgggtcgtagcgaccattctgtgaccttatcctgggtggctcccatgagtgat ggtggcgggggtctatgtggttatcgtgtggagatgaaggaggcatccacaggccagtgg cagttgtgccacgacttggtacctggcccagagtgcgtggtggacggcctggtccctggg aagacctaccgcttccgagtggcagctgtgggtccagcaggtgctggggagcctgtacat ctgccccagatggtcaagatagccccagccccagccccagccccagccccagccccagcc ccagcaacacggcaggcagtggttggtgaagacctgtgtctggagttggaagtggcagct gatgctggcgaggtcgtctggcacaagggaacagagcgcatccagcctggcgggcacttt gagatcctctcgcagggtcagcggcagatgctggtgatcaagggctttaggaccgaagac caaggggagtaccgctgtggtcccatccagggtctgccctcctcaggagctgccacgttc aatgtggttatgacctcaggctctggggatgaggtcccggcacagcctagcctgcctcct gaggcagcccaggagggtgacctgcatctgctttgggaggcccttgcccggaagcgccgc atgagtcgggagcccacgctggactccatcagcgagctgcctgaggaagacagccgtgtg cagcatctgcggcaggaggcagaagagacagctcccgacctctctgagggctactctaca gcggatgagctagcacgcacaggagaggccgacctctcacacaccagctctgacgatgag tctcgggctggcactccttccctagttacctacctcaagaaggccgggggtcctgggatc tcacccttggccagcaaggtgagcttcctagtgaccacgtctgtgaagccacaaaagcag caggagccagttgtgcccacgtgcccaccaccgggagacttgagtgcagcagatttgaac gatccatccctggacaaggcagctgtgaagatccaggcagcctttaagggctacaaagtg cggaaggagatgaagcagcaggaagggcctgtgttctcacgaacatttggggacacagag gcacaggttggggatgtgctgcggctggagtgtgtgctggccaccaaggctgatatgcgg gcctgttggttgaaggatggcatcgagttaacagatgggcgccactaccacatagaccag ctcaaggacggtacctgctctctgctggtcactggcctgggccccactgactctggccgt tacacctgtcaggtgaacaccaagtttggccgtgtgagccacagtgcctgcgtggtggtc agtgggacagagagcgaggccgagagctcctctggtggtgaactggatgatgctttccgc cgggcagcgagacgcctgcaccgcctcttccgcaccaagagtccagctgagctttcagag gaggaactcttcctcagcgctgatgaaggccccgcggagccggaggagcccgcagactgg caaacataccgagaggatgaaaactttgtgtgcatccgttttgagtcccttgcggaggcc cgccgggcagttacctgtttccgtgacatgtttgctaccatgggcatcggggtggagatc agcctaggggagcagggaccccggggagtggagatgcgcatcggcaaggtggcccccact gtcacccctgcagtgtcacttgcaaagacgcctggcctgcagacttcagacgctgcccca gtgttcctgaccgagctgcagaaccaagatgtgcaggatggataccccatgagcttcgac tgcgtggtaacaggccagcctgtgcccagtgtgcgctggttcaaggatgggaagttgcta gaagaggatgaccactatatgatcaacgaggaccaacaggggggtcaccagctcatcatc acagctgtggtgccggcagacatgggcgtctaccgctgcctggcggagaacagcatgggc gtctcgtccaccaaggctgagcttcgtgtggaattgaccagcacagactatgacactgct gcggatgctactgagacctcatcctacttcagtgcccagggatacctgtccagccgggag caagagggaacagagtcagatgaggggcagcttccccaggtgctggaggagctgaaagac ctccaagtggcccctggcacacgcctggccaagttccagctcaaggtgaaaggctatcca gctcccaaactgtattggttcaaagatggccagcccctgactacatctgaccacatccgc atgactgacaaaaagaccctgcacaccctggagattgtctctgtcactcgggaggacagc ggccagtatgcagcctacatcagcaatgctgtgggtgctgcctattcgtcagcccggctg ctggtccgaggtcccagtgaaccagaagagaagccagcatcagatgttcacgagaggctg gtgccaccccgaatcctggagaagttcacccccaagaaagtgaagaggggatccagcatc accttttcagtgaaggtggaaggacacccagcccccagtgtgcattggctcaaggaggag gcagagaagggagtgctgtggattggccctgacaccccgggctacaccatggccagctct tccaagcagcatagcctggtcctgctcgacgtaggccggcagcaccagggcacctacaca tgcattgccaccaatcctgctggccaggcgctctgctctgccagtctgcacatctctggc ttggccaaagaagaagagcaggagagagtgaaggaggccctcatttcctccttcctgcaa gggacgagccacgctgtctcagcccagatgtcagaatccacaggttttgctgatcttgtc gggcaaaggaaaggtgagtctctggtggctgaggaggcccacagtcacctgtcccttgct gaggtgggcacagaagagttcctgcagaaactcacctcgcagatcaccgagatggtgtcg gccaagttctctcaggccaaactccaggtgcctggaggtgacagcgatgaagagtccaag acaccatctgcctctcctcggcatggccggtcacgtccttcctccagtgttcaagagtcc tcctcagagtcagaggatggggactcccgtggtgagatctttgacatctacgtggtcaca gctgactatctaccgctgggagccgagcaggatgctatcattctgagagaaggccagtac gtggaggtccttgactctgcccatcccctgcgctggcttgtacgcaccaagcccaccaaa tccagtccttccaggcagggctgggtgtcgcctgcctacctggacaagaggctcaagctg tctcctgagtgggggcccactgaggcccccgagttccctggcgaggccgtgtctgaggat gagtatagaacgaggctgagctctgtcatccaggagttgctgagttcagagcaggccttt gtgggtgagctgcagttcttggagagccaccacatgaagcacctggaccgatctccccgc gtccccgcagctgtggccagccagaagacagtcatctttcgtaatgtgcaggacatcagc catttccacagcagcttcttgaaggagctgcagggctgtggcaccgatgatgatgtggcc atgtgcttcatcaagaaccaggaggcctttgagaagtacctcgagttcctggtgggccgt gtgcaagctgaatcagtggttgtcagcaccccagtccaggaattctacaagaaatatgca gaagagacactgtctgccaaggaccccacacagccaccccctcctccccttcagcactac ctggagcagccagtggaacgggtgcagaaataccaggccttgctgaaggagctaatccgc aacaaggcccgcaacagacagaactgtgcgctgctggagcaggcctacgctgtggtgtct gccctgcctcagcgtgccgagaacaagctgcatgtttctctcatggagaactacccagga accttggaggccctgggagagcctatccgccagggccacttcatagtgtgggaaggggcc ccaggggcccggatgccttggaagggccacaaccggcacgtcttcctcttccgaaaccac ctggtgatctgcaagccccggagagactctcgaaccgacaccttcagctatgtgttccgg aacatgatgaagctgagtagcatcgacctgaatgaccaggtagagggggatgaccgtgcc tttgaggtgtggcacgaacgggaagactctgtgcgcaagtacctgctgcaggcacggacc gtcatcatcaaaaactcctgggtgaaggagatctgtggcatccagcaacgccttgcccag cctgtgtggcgttcccctgagtttgaagaggaactagctgactgcacagctgagctgggt gaaacggtcaagctagcatgccgagtgacgggcacgcctaagcctattgtcagctggtac aaagatgggaagccagtggaggtggacccgcaccacatcctcattgaagaccctgacggc tcctgcaccctcatcttggacaaccttactggcatagactctggccagtacatgtgtttt gcagccagtgctgctggcaacgccagcaccttggggaagattctagtacaagtgccccca cggtttgtgaacaaggtccgggccacaccctttgtggagggagaggacgcacagatcacc tgcacagtggaaggagccccgtaccctcagatcaggtggtacaaggatggtgccctgcta accctgggcaacaggtaccggatgttgaatgaaccccgcagtggtgtgctggtgctggtg atccaggcagccagcaaggaggacctgggacactatgaatgtgagttggtgaaccggttg ggctcaacacgtggtggtggagaactatacatgcagagccctgcactgcgtgcccgggac cagcaccatcgggaacagattgtggctgccgtagaagtcactgagcaggagacaaaagtc cccaagaaaaccgtcatcatagaggagactatcaccaccgtggtgaagagtccacgtggc cgacgacagtcccctggcaagtctccctcccgttcaccttcccgccgctctgccagtcca cggagaccagggctgttggcccccgagaggctgtacccaccagggaccagcccatcccgg aggcttgaagtagaacaaggcaggaaagccccggtgcctgcgttgtatgtgacagaagcg gaggtccgcacgccagcctcgcagtcacagcccaagtggttagaggtggaggaaaccatc gaagttcgggtgaagaagacagggtcgcggggtgcatctcctgtccgagagatgaccagc catggagagggaatcctcttcacactgcctggcgggatccctggtagggacccaaatgcc aacaactccaacaacaagagcgtgtaccaggaagcccggacctggggtcccactgcggtc catgttggtgaacctttcgtcttccaagtggactcggtgggcaatgtggactgggtagct gctagctctgagccagagcaggtcagagcctcccagaaggaagaggacactgagagggaa gaaggatgcagtgatggagacgagaataccttcctgatggaagagccacaggatgcggac agccttcagggccgtgaccccaaaatcctcacacacaatggccgggtgctgacattggct gacctggaagattatgtaccccaggaaggagagacttttggctgtggggaccccaccccc agcacctctgatgaccccccctgtgaagtctccgtgctccagagagagatcggcgagccc atggtggggcaacctgtcctgctcaatgtggggcgtcctccaggcaccggtgccaccccc agcttcttcaggccaggttcccaggtccacagccctgagagcgtctccttccttttgcgt ggctccccaagccagggacaacagcagcagcagcggcagcagcacgtgaggtggaagaag gagggcgacacctccgtggagggctctgcccactccacccaggacggagttgaccaacaa gctgcttctgtcctttggaggctgctgggctcagaagccctcggcccctcctcaggggat ctcccgaataccagacaaagtgagccacctgcatttcaagaggctgcgtcccagatccca ggcgcagcttcaggcacacctggtgaacttccagaggtctcacagcctggcacacacaag ggcctggagcaggagacgacaagttctgggtcccagggatggactgtacccattcgggtg gagggaacagcctggccaggtgcaggcaccgggcagctgctcttggatgtgcacagccaa gtcatcatggagaccacacagaggacctacgtgtgccaagctcctgacacaggtgtcaca agggccccatccatgcaggtccctattgaggatgtgcaagtacaagtaggggacatggcc cagtttgatgctgtcattgaaggccacccaccacccatagtgacttggtataaggacagc acccagctgacgagcagtgcccggctgagccagcggcaagatggaacgacatattccttg gtgttgactgatgtggctccacacgatgccggtgtctacacatgtgttgccaataatgca ggtggacaggtgctctgcaaggcagagctgctggtccacgggggggacaagctagatgcc gaaaagcaagtctatcggagaaaactgcattccttctatgaggttcaagaagagattggg aggggtgtgtttgggttcgtgaaaagggttcagcacaaaggaaacaagatgtcctgtgcc gccaagttcatccccctgcggagcaaaactcgggcccaggcataccaggaacgagacatc ttggctacactcggccacccactggtcactgggctcctggatcaatttgagacccggaag actctcatccttatcttggaactgtgctcgtctgaggagctgctggatcgactcttcaag aagggtgtcgtgactgaagccgaggtcaaagtctacatccagcagctggtggaaggcctg cactatttgcacagccatggtatcctccacctggacataaagccccccaacatcctgatg gtgcacccagctcgggaagacatcaagatctgtgactttggctttgcccaaaagatcacc ccttcagagccgcagtatagcaagtatggctcacccgaattcgtgtccccagagatcatt gagcagaatcctgtgagcgagggctcagacatctgggctatgggcgtcatctcctatctc agcctcacctgctcatccccgtttgctggagagagtgaccgtgccaccttgctcaatgtt ttggaggggcgggtctcttggagcagtcccatggctgctcatctgagtgaggatgccaag gactttatcaaggccacgctgcaaaagacccccagggcccggcctagtacttcccagtgc cttgcccacccctggttcctgaattccatgcctgctgaggaggcccacttcatcaacacc aaacagctcaagttccttcttgcacgaagtcgctggcagcgttccttgatgagctacaag tctatcctggtgatgcgctccatccctgagctgctccagggtcctccagacagtccatct ctaggagtggctcggcacctacgaggggaagccagtggctcctctagctcatcatcttcc tcagacaacgagcttgccccatttgccagggctaagtcactgccaccttcccctgtgact cactcgccactgctgcaccctcggggctttctgcggccttcggccagcctcccagaggag acagaggccagcatgcccactgctgatgtggctgtgccagcatccccgcagagtgctggg cctccggcaagcccaggttgcgtgccccggcacagcgtcatcagcagcctgttctaccag caagctggtgagggtgcagagcgtgggagcaaaacgtcgggtgccaagaggcaccttgct cgtaggcggcacctgctgaagggtgggtacattgcaagggccctaccgggtctgcgtgag cccctcatggagtacagcctgttggaggaagaggccgctagggaggagcaggcctctctg atgaccaagacaccctcctttgagactgccctgcgactacctagttccaatgtcagagag gtcccaggccgaagccgctccctggacaacccaccagtcacgaccggcccctctcccgag gcatgcaaggaacaattcctgttcccaccctcctcggggttgactcatgaaaccactgcc aaggatggggggcacaaagaggtgttcttgcaggagtctgtctcctttccacctatgagt ggtgacttgaggcctgggaagcaagagggatcatcccaggacagttgtcgagggaaacca acctcttcctgtcactctgaactgggttctgggtcccaggagggctgtggccctccatca tctcaatcgcttggctccttacctccacagtcattgaagaaggagctctcaacgtcctgt ggcccacacttttcagaacagcctcaggtagccccattcccaactcaagtaagccctctt ctgggttctgagaaggaacctcaggacggctctctatctgaagggccagttccagttccc tccagttccccagggtcagcctcccaagtagatgcatccttggatactgaaggcttgtct gaagctggggacacatgtgacatcactcctcctccacagcggcctcaggagcaggccacc acccggaagttctctctggagtcccgtgggggctatgcaggggtggcaggctatggcact ttcgcctttggtggggacgcaggggggatgctagggcagggtcctctctgggccaggatg gcctgggctgtgtcccagtcctcagaagagcaggatgaagccgtgactgagagtcctcaa cctctggagagctcggggcccattactgaggccagtggggttcccctaaggacctctccg agcctcaccccttgggaggaagttgagcaggtttccctggtacagatccgggatctgtct ggcgatgcagaagcagccgacaccatctccttggacatttctgaggtcgatcctgcctac ctcaacctctctgatctatatgacatcaaatatctcccatttgagttcatgatcttcagg agggtccccaaacctgtagagcagccagagtcacctgactcagaaaccgaagccgggcaa gggctggcagatttcctggaggaggccgcgtggccctggccaggcgagctgggactgcgt gctggtctggagattacagaggagccagaggagccaggggacctggaagcactgctgggc gaggctgctgtgggcaggaagcgcaagtggtccccctcccggggcctcttccaattccct gggaggtgcctgtcgggagaggagcctgcggagcttgggctgcgccagagggtgaaggct tccatggctcacatctccaggatcctgaagggcaagccagaaggtcctgagagggaaggg cctcccagaaagaaggcaggcctaggttccttccggctgtcaggcctgaagggcagggac caagcaccatccttcctaagagaactctcagacgaggctgtggtcctgggccagtcagtg acactggcctgccaggtgttggcccagccaactgcccaggctacttggagcaaagatggg gtcctcctggagagcagtggccacctcctcatctcctccaccctgaagaacttccagctg ctgaccatcctggtggtgaaggaggaggatctgggcacatatacctgctgtgtgagcaat ccgctggggacagcagtcactacaggtgtcctccggaaagcagagcgcccttcatcttct ccgcgcccggaggttggggaactatacacggatgcggtgctgctggtctggaagcctgtg gaatcctgcggcccagtgacctacattgtgcagtgctgtatagaaggaggcagctggaca accctggcttccgacatctctgactgctgctgcctcactggcaagctacccaggggtggc gtgtataccttccggacagcgtgtgtcagcaaagcagggatgggtccctacagcagcccc tcagaacaggtcctcctcggaggacccaaccacctagcctctgaggaagaaagcagccgg gggaggccagcccagcttctccccagcacaaagacctttgccttccagatgcagattcgg aggggacgcttcagtgtggtgcggcagtgtagggagaaggcaagtgggcgggccctggct gctaagatcattccctaccagcctgaggacaagacagctgtactaagagaatatgaggca cttaagagactgcaccacccacatctggcccaactccatgccgcctacctcagtccccgg cacctggtgctcatcctggagctgtgctctggtcctgagctgctaccctctctggcagag agggactcctactcagagtctgatgtgaaggactacctgtggcagatgctgagtgccacc cagtacctgcatgcccaacacatcctgcacctggacctgaggtctgagaacatgatggtc actgagtacaacctgcttaaggttatagacctggggaatgcccagagtctcagccaagag aaggtcccagcccctgagaacttcaaagactacctggagaccatggaacttctggaaggc caaggggctgtgccacagacagacatctgggctattggtgtaacagctttcattatgctg agtggcgagtacccagagagcagcgaggggactcgcgacctgcagaaaggcttgcgcaag ggactcattcggttgagtcgctgctatgcaggattatcaggaggagcggtagccttcctg cagagttccttatgtgctcaaccctggggccgcccgtgcgcttccacctgcttgcaatgc gggtggctgacagaggagggccccaccggctcccggcccacacccgtaaccttccctacc gtgcggttgcgtgcctttgtgcgcgagcgcgagaagcggcgtgcgctcctctacaagaag cataacctggcccaggtgcgctga

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