KEGG   Mus pahari (shrew mouse): 110331335
Entry
110331335         CDS       T05929                                 
Symbol
Map2k6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mpah  Mus pahari (shrew mouse)
Pathway
mpah04010  MAPK signaling pathway
mpah04015  Rap1 signaling pathway
mpah04218  Cellular senescence
mpah04380  Osteoclast differentiation
mpah04620  Toll-like receptor signaling pathway
mpah04664  Fc epsilon RI signaling pathway
mpah04668  TNF signaling pathway
mpah04750  Inflammatory mediator regulation of TRP channels
mpah04912  GnRH signaling pathway
mpah04935  Growth hormone synthesis, secretion and action
mpah04936  Alcoholic liver disease
mpah05014  Amyotrophic lateral sclerosis
mpah05022  Pathways of neurodegeneration - multiple diseases
mpah05132  Salmonella infection
mpah05135  Yersinia infection
mpah05145  Toxoplasmosis
mpah05161  Hepatitis B
mpah05163  Human cytomegalovirus infection
mpah05167  Kaposi sarcoma-associated herpesvirus infection
mpah05169  Epstein-Barr virus infection
mpah05170  Human immunodeficiency virus 1 infection
mpah05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mpah05417  Lipid and atherosclerosis
mpah05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mpah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110331335 (Map2k6)
   04015 Rap1 signaling pathway
    110331335 (Map2k6)
   04668 TNF signaling pathway
    110331335 (Map2k6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    110331335 (Map2k6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110331335 (Map2k6)
   04664 Fc epsilon RI signaling pathway
    110331335 (Map2k6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    110331335 (Map2k6)
   04935 Growth hormone synthesis, secretion and action
    110331335 (Map2k6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110331335 (Map2k6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    110331335 (Map2k6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110331335 (Map2k6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110331335 (Map2k6)
   05161 Hepatitis B
    110331335 (Map2k6)
   05163 Human cytomegalovirus infection
    110331335 (Map2k6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110331335 (Map2k6)
   05169 Epstein-Barr virus infection
    110331335 (Map2k6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110331335 (Map2k6)
   05135 Yersinia infection
    110331335 (Map2k6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110331335 (Map2k6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110331335 (Map2k6)
   05022 Pathways of neurodegeneration - multiple diseases
    110331335 (Map2k6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110331335 (Map2k6)
   05418 Fluid shear stress and atherosclerosis
    110331335 (Map2k6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110331335 (Map2k6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mpah01001]
    110331335 (Map2k6)
Enzymes [BR:mpah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     110331335 (Map2k6)
Protein kinases [BR:mpah01001]
 Serine/threonine kinases: STE group
  STE7 family
   110331335 (Map2k6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 110331335
NCBI-ProteinID: XP_021067481
Ensembl: MGP_PahariEiJ_G0018490
LinkDB
Position
14:77644247..77767558
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSK
ERPTYPELMQHPFFTVHESKAADVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaagattccaaaagaagcgttt
gaacaaccccagaccagttccacgccacctcgggatttagactccaaggcttgcatatct
attggaaaccagaactttgaggtgaaggcagatgacctggagccaatagtggagctggga
cgaggtgcgtacggggtggtggagaagatgcgtcacgtgcccagcgggcagatcatggcg
gtgaagcggatacgggccacagttaatagccaggagcagaaacggctgctgatggatttg
gatgtttccatgaggacggtggactgtccatttactgtgaccttctacggtgcactcttc
cgggagggcgacgtgtggatctgcatggagctcatggatacgtcactagataaattctac
aaacaagttattgataaaggccaaacaattccagaggatatcttaggaaagatagcagtt
tctattgtaaaagcgttagaacatttacacagtaagctgtctgttatccatcgagacgtc
aagccttcgaatgtgctcattaacacactgggccaagtgaagatgtgtgactttggaatc
agtggctacctggttgactctgttgctaaaacgatcgatgccggttgcaaaccatacatg
gctcctgaacggataaatccagagctcaaccagaaggggtacagtgtgaagtctgacatt
tggagtctgggcatcaccatgatcgagctggccatccttcggtttccctatgattcatgg
ggaacgcccttccagcagctaaaacaggtggtcgaagagccctctcctcagctcccagca
gacaagttctctgcggactttgttgactttacctcacagtgcttgaagaaaaattccaaa
gaacggcccacatacccagagcttatgcaacatccatttttcaccgtacatgaatccaaa
gcagcagacgtggcatcttttgtaaaactgatacttggggactaa

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