Mus pahari (shrew mouse): 110331346
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Entry
110331346 CDS
T05929
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah04140
Autophagy - animal
mpah04141
Protein processing in endoplasmic reticulum
mpah04210
Apoptosis
mpah04932
Non-alcoholic fatty liver disease
mpah05010
Alzheimer disease
mpah05012
Parkinson disease
mpah05014
Amyotrophic lateral sclerosis
mpah05016
Huntington disease
mpah05017
Spinocerebellar ataxia
mpah05022
Pathways of neurodegeneration - multiple diseases
mpah05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
110331346 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110331346 (Ern1)
09143 Cell growth and death
04210 Apoptosis
110331346 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110331346 (Ern1)
05012 Parkinson disease
110331346 (Ern1)
05014 Amyotrophic lateral sclerosis
110331346 (Ern1)
05016 Huntington disease
110331346 (Ern1)
05017 Spinocerebellar ataxia
110331346 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
110331346 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110331346 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110331346 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpah01001
]
110331346 (Ern1)
Enzymes [BR:
mpah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110331346 (Ern1)
Protein kinases [BR:
mpah01001
]
Serine/threonine kinases: Other
IRE family
110331346 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
110331346
NCBI-ProteinID:
XP_021067498
Ensembl:
MGP_PahariEiJ_G0018454
LinkDB
All DBs
Position
14:complement(73701177..73796670)
Genome browser
AA seq
977 aa
AA seq
DB search
MPSRWLLLLLALLLPPPGPGSFGRGSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINIVGQTSDHTPTTV
SQDVEEKLFRAPAKPEAPVDSMLKDMASIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQ
FQKELEKIQLLQQQQLPFHPHGDLTQDPEFLDSSGPFSESSGTSSPSPSPRASNHSLHSS
SSASRPGTSPSLEQGDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAV
GRHSFSRHSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGNHPFGKSLQ
RQANILLGACNLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPVEVQETLGSVPDDFVRYFTSRFPNLLSHTYHAMELCRHERLFQTY
YWHEPTEPQPPVIPDAL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccgtcccggtggctgttgctcctgctggcgctgctgctaccgccgcccggccccggg
agttttggaagaggcagcacagtaacactgcctgaaaccttgttgtttgtttcaaccctg
gatggaagcttgcatgctgtcagcaagaggacaggctccatcaagtggactttaaaagaa
gatccagtcctgcaggtcccaacacacgtggaagagcctgctttcctcccagatcccaat
gatggcagtctgtacacacttggaggcaagaacaacgaaggcctgacgaaacttcccttt
accatcccagaattggttcaggcctccccatgccgaagttcagatggaatcctctacatg
ggtaaaaagcaagatatttggtatgttatcgacctcctgactggcgagaagcagcagact
ttgtcatcggcctttgctgatagtctctgcccatcaacttcccttctgtatcttggacgg
acagaatacaccatcaccatgtatgacaccaagacccgggagctccgctggaatgccacc
tattttgactatgcagcctcactgccggaagatgatgtggactacaagatgtcccacttt
gtgtccaatggcgatggactggtggtaactgtggacagtgaatctggggatgtcttgtgg
atccaaaactatgcctctcctgtggtggccttctacgtctggcagcgggagggcctgaga
aaggtggtacacatcaacgttgctgtggagactctacgctacttgaccttcatgtccggg
gaagtggggcgcatcaccaagtggaagtatccattccccaaggagacagaggccaagagc
aagctgacgcctactctgtatgttgggaagtattccaccagcctctatgcctctccctca
atggtgcatgagggggttgctgtcgtgcctcgaggcagcactcttcctttgctggaaggc
ccccagacagatggtgtcaccattggagacaaaggagagtgtgtgatcactcccagcaca
gacctcaagtttgaccctggactcaaagggaagagcaagctgaactacttgaggaattac
tggcttctcataggacaccatgaaactcctctgtctgcatccaccaagatgctggagaga
tttcctaacaacctgcccaaacatcgagaaaatgtgattcctgctgattcggaaaaaagg
agctttgaggaagttatcaacatagttggccagacttcagaccacacaccgaccaccgta
tctcaggatgtggaagagaagctcttccgtgcccctgccaagcctgaggcccccgtggac
tccatgctcaaggacatggctagtattatcttgagcaccttcctgctggttggatgggtg
gcgttcatcatcacttaccccctgagcatgcatcagcagcgtcagctccagcaccaacag
ttccagaaggagctagagaagattcagctcctgcagcagcagcagctgcccttccaccca
cacggagaccttacccaggaccctgagttcctggattcatctggccccttctcagagagc
tcgggcaccagcagccccagcccatcccccagggcctccaaccactccctccactccagc
agctctgcctccaggcccggcaccagtccctctctggagcagggtgatgaggatgaagaa
accagaatggtgattgttgggaaaatttcattctgccccaaggatgtcctgggtcatgga
gctgagggcacaattgtatacaaaggtatgtttgacaaccgagatgtggctgtgaagagg
atcctccctgagtgttttagctttgccgaccgtgaggtccagctgcttcgagaatcagat
gagcacccaaatgtgatccgctacttttgcacagagaaggaccggcagttccagtacatt
gccattgagttgtgcgcagctaccctacaagagtatgtggagcagaaggacttcgcccat
cttggcctagagcccatcaccttgcttcatcagaccacctcaggcctggcacatctgcat
tctctcaacattgttcacagagacctgaagccccacaacattctcctctccatgcccaac
gcgcacggcaggatcaaggcgatgatctctgactttggcctctgcaagaagctggcggtg
ggcaggcacagcttcagccgccattcaggggtgcctggcacggaagggtggattgcccca
gagatgctgagtgaggactgtaaggacaaccctacctacacggtggacatcttttctgca
ggctgtgtcttttactatgtcatctctgagggcaaccatccttttggcaaatccttgcag
cggcaggccaacatcctcctgggcgcctgcaaccttgactgcttccactcagacaagcat
gaggacgtcattgctcgtgaattgatagagaaaatgattgcaatggaccctcagcagcgc
ccctctgcaaagcacgtgctaaaacaccccttcttctggagcctggagaagcagctccag
tttttccaggatgtgagtgaccgaatagaaaaggaggccttggacggtccgatcgtacgg
cagttggagagaggcgggagagctgtggtcaagatggactggcgggagaacatcactgtc
cccctgcagacagatctgcgcaaattcagaacctacaaaggtggctctgtcagagatctc
ctccgagccatgagaaataagaaacaccactaccgggagctccctgtggaggttcaggag
acgctgggctccgtcccagatgactttgtgcgctacttcacgtcccgcttccccaacctc
ctctctcacacctaccacgccatggagctgtgcagacatgagagactcttccagacctac
tactggcatgagcccacagaaccccagcctccagtgattccagatgccctctga
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