Mus pahari (shrew mouse): 110335780 Help Entry 110335780         CDS       T05929                                  Symbol Sos1 Name (RefSeq) son of sevenless homolog 1   KO K03099   son of sevenless Organism mpah  Mus pahari (shrew mouse) Pathway mpah01521   EGFR tyrosine kinase inhibitor resistance mpah01522   Endocrine resistance mpah04010   MAPK signaling pathway mpah04012   ErbB signaling pathway mpah04014   Ras signaling pathway mpah04062   Chemokine signaling pathway mpah04068   FoxO signaling pathway mpah04072   Phospholipase D signaling pathway mpah04150   mTOR signaling pathway mpah04151   PI3K-Akt signaling pathway mpah04510   Focal adhesion mpah04540   Gap junction mpah04630   JAK-STAT signaling pathway mpah04650   Natural killer cell mediated cytotoxicity mpah04660   T cell receptor signaling pathway mpah04662   B cell receptor signaling pathway mpah04664   Fc epsilon RI signaling pathway mpah04714   Thermogenesis mpah04722   Neurotrophin signaling pathway mpah04810   Regulation of actin cytoskeleton mpah04910   Insulin signaling pathway mpah04912   GnRH signaling pathway mpah04915   Estrogen signaling pathway mpah04917   Prolactin signaling pathway mpah04926   Relaxin signaling pathway mpah04935   Growth hormone synthesis, secretion and action mpah05034   Alcoholism mpah05160   Hepatitis C mpah05161   Hepatitis B mpah05163   Human cytomegalovirus infection mpah05165   Human papillomavirus infection mpah05200   Pathways in cancer mpah05205   Proteoglycans in cancer mpah05206   MicroRNAs in cancer mpah05207   Chemical carcinogenesis - receptor activation mpah05208   Chemical carcinogenesis - reactive oxygen species mpah05210   Colorectal cancer mpah05211   Renal cell carcinoma mpah05213   Endometrial cancer mpah05214   Glioma mpah05215   Prostate cancer mpah05220   Chronic myeloid leukemia mpah05221   Acute myeloid leukemia mpah05223   Non-small cell lung cancer mpah05224   Breast cancer mpah05225   Hepatocellular carcinoma mpah05226   Gastric cancer mpah05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mpah00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     110335780 (Sos1)    04012 ErbB signaling pathway     110335780 (Sos1)    04014 Ras signaling pathway     110335780 (Sos1)    04630 JAK-STAT signaling pathway     110335780 (Sos1)    04068 FoxO signaling pathway     110335780 (Sos1)    04072 Phospholipase D signaling pathway     110335780 (Sos1)    04151 PI3K-Akt signaling pathway     110335780 (Sos1)    04150 mTOR signaling pathway     110335780 (Sos1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     110335780 (Sos1)    04540 Gap junction     110335780 (Sos1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     110335780 (Sos1)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     110335780 (Sos1)    04660 T cell receptor signaling pathway     110335780 (Sos1)    04662 B cell receptor signaling pathway     110335780 (Sos1)    04664 Fc epsilon RI signaling pathway     110335780 (Sos1)    04062 Chemokine signaling pathway     110335780 (Sos1)   09152 Endocrine system    04910 Insulin signaling pathway     110335780 (Sos1)    04912 GnRH signaling pathway     110335780 (Sos1)    04915 Estrogen signaling pathway     110335780 (Sos1)    04917 Prolactin signaling pathway     110335780 (Sos1)    04926 Relaxin signaling pathway     110335780 (Sos1)    04935 Growth hormone synthesis, secretion and action     110335780 (Sos1)   09156 Nervous system    04722 Neurotrophin signaling pathway     110335780 (Sos1)   09159 Environmental adaptation    04714 Thermogenesis     110335780 (Sos1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110335780 (Sos1)    05206 MicroRNAs in cancer     110335780 (Sos1)    05205 Proteoglycans in cancer     110335780 (Sos1)    05207 Chemical carcinogenesis - receptor activation     110335780 (Sos1)    05208 Chemical carcinogenesis - reactive oxygen species     110335780 (Sos1)    05231 Choline metabolism in cancer     110335780 (Sos1)   09162 Cancer: specific types    05210 Colorectal cancer     110335780 (Sos1)    05225 Hepatocellular carcinoma     110335780 (Sos1)    05226 Gastric cancer     110335780 (Sos1)    05214 Glioma     110335780 (Sos1)    05221 Acute myeloid leukemia     110335780 (Sos1)    05220 Chronic myeloid leukemia     110335780 (Sos1)    05211 Renal cell carcinoma     110335780 (Sos1)    05215 Prostate cancer     110335780 (Sos1)    05213 Endometrial cancer     110335780 (Sos1)    05224 Breast cancer     110335780 (Sos1)    05223 Non-small cell lung cancer     110335780 (Sos1)   09172 Infectious disease: viral    05161 Hepatitis B     110335780 (Sos1)    05160 Hepatitis C     110335780 (Sos1)    05163 Human cytomegalovirus infection     110335780 (Sos1)    05165 Human papillomavirus infection     110335780 (Sos1)   09165 Substance dependence    05034 Alcoholism     110335780 (Sos1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     110335780 (Sos1)    01522 Endocrine resistance     110335780 (Sos1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_19 PH_10 IQ_SEC7_PH RHG20_PH DUF6018 Motif Other DBs NCBI-GeneID:  110335780 NCBI-ProteinID:  XP_021073789 Ensembl:  MGP_PahariEiJ_G0020898 LinkDB All DBs Position 18:complement(46264552..46349882) Genome browser AA seq 1319 aa AA seqDB search MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSY DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCLEDLAEELAFDPYESYAR DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL EEKSEDQEDKECMKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL PGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA LISLQYRSTLERMLDVTVLQEEKEEQMRLPSADVYRFAEPDSEENILFEENVQPKAGIPI IKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADR IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQVPSRQRKI LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSK RRRVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESPASAP NSPRTPLTPPPASGTSSNTDVCSVFDSDHSASPFHSRSASVSSISLSKGTDEVPVPPPVP PRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLL PPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLP SPPLTQEMDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS NT seq 3960 nt NT seq  +upstreamnt  +downstreamnt atgcaggcgcagcagctgccctacgagtttttcagcgaggagaacgcgcccaagtggcgg gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcaccctactcttgagtct aatgatgatgctcttcagtatgttgaagaattaattttgcaattactaaatatgctgtgc caagctcagccccggagtgcttcagatgtggaggaacgtgttcaaaaaagttttcctcat ccaattgataagtgggcaatagctgatgcccaatcagctattgaaaagaggaagagaagg aatcctttatccctgccagcagaaagaattcatcatttgttaagggaggtcctcggttat aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagat attttaaagttggtggggaattatgtaagaaatatacggcattatgaaattacaaaacaa gacattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta gaggatataaatatcttatctttaactgatgaagaaccttccacctcaggagaacaaact tactatgatttggtaaaagcattcatggcagaaattcgacagtatataagagaattaaat ctaattataaaagtttttcgagaaccctttgtctctaattccaaattgttctcatcttat gatgtagaaaacatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg ggccatatagaagacactgtagagatgacagacgaaggcagcccccacccattagtagga agctgtttggaagacttagcagaagaactggcatttgatccatatgaatcatatgctcgg gatattttacgacctggattccatgaccgttttcttagtcagttatcaaagcctggggca gcactttatttgcagtcaataggcgaaggcttcaaagaagctgttcagtatgttttgccc cggctgctgcttgcccctgtgtaccactgtctgcattactttgaacttctgaagcagtta gaagaaaagagtgaagatcaagaagacaaggagtgtatgaagcaagcaataacagccctg cttaacgtccaaagtggcatggaaaaaatttgctccaaaagtcttgcaaaacgaagacta agtgagtctgcatgtcggttttacagccagcagatgaaggggaaacaactagccatcaag aaaatgaacgagatccagaagaatattgatggttgggaggggaaagacattggacagtgc tgcaatgagttcataatggaaggaactcttacacgtgtaggagccaaacacgagagacac atatttctcttcgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactc cctggtgctagcagtgcagaatatcggcttaaagaaaaattttttatgcgaaaggtacaa attaatgataaagatgataccagtgaatacaagcatgcttttgaaatcattctgaaagat ggaaatagtgttatattttctgccaagtcagctgaagagaaaaacaactggatggcagca ctgatatctttgcagtaccgcagcaccctggagaggatgctggacgtaacagtgctgcag gaagagaaggaggagcagatgaggctgcctagtgctgatgtgtacaggtttgcagaacct gactccgaggagaatattctattcgaagagaatgtgcagcccaaagctgggatccccatt atcaaagcagggactgtggttaaactcattgagaggcttacataccatatgtacgcagat ccaaattttgttcggacgtttcttacaacatacagatccttttgcaaacctcaagaacta ctgagtcttctaatagaaagatttgaaattccagagcctgagccaacagaagctgatcgc atagctatagagaacggagaccagcccctgagtgcagagctgaagaggtttaggaaggaa tatatccagcctgtgcagctgagggtgttgaatgtgtgtcggcactgggtggagcaccat ttctatgactttgaaagagatgcagaccttttacagagaatggaggaatttattggaaca gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaagataatccaaaggaaa aaaattgcaagagacaatggcccaggtcataatattacatttcagagttcacctcccaca gttgagtggcacataagcagacccgggcacatagagacttttgacttgctcaccttacac ccaatagaaattgctcgacaactcactttacttgaatcagatctataccgagctgtgcag ccatcagaattagttggaagtgtgtggacaaaagaagataaagaaattaattctcccaac cttctgaagatgattcggcacaccactaacctcactttgtggtttgagaaatgtattgta gaaacagaaaacttagaagaaagagtagctgtagtgagtcggataattgagattctacaa gtctttcaagagctgaacaacttcaatggtgtcctggaagttgtcagtgctatgaactca tcgcctgtttacagactagaccacacatttgagcaagtaccaagtagacaaaggaaaatt ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg tctattaatccaccatgtgtgcctttctttggaatttatctcacaaatatcttgaagaca gaagaaggcaaccctgaggtcctaagaagacatggaaaagagctcatcaacttcagcaag aggaggagagtggctgagataacaggggagatccagcagtaccaaaaccagccttactgc ttacgggtggagtcagacatcaagaggttctttgaaaacttgaatccaatgggaaatagc atggagaaagaatttacagactatctattcaacaaatccctagaaatagagccgcggaac cctaagcctctcccgagattcccaaaaaaatacagctatcccctaaaatctcctggtgtt cgtccatcaaatccaagaccaggaaccatgagacatcccacgcctctgcagcaggagcca agaaaaattagctacagtaggatccctgagagtgagacagaaagtccagcgtctgcacca aattccccgagaacaccactgacacctcctcctgcatctggcacttccagtaacacagat gtttgcagcgtgttcgattctgaccattcagcaagcccttttcattcaagatctgcttca gtctcatctataagtttatccaagggcactgacgaagtgcctgttccccctcctgtaccc ccacgaaggcgtccagagtctgccccagctgaatcctccccatccaagattatgtctaag cacttggacagccccccagctattcctcctaggcaacccacatcaaaagcctattcccca cgatattcaatatcagatcggacctctatatcagatcctcctgagagccctcccttgtta ccaccacgggaacctgtgaggacacctgatgttttctcaagctcgccattacatctccaa cctcctcctttgggcaaaaagagtgatcatggcaatgccttcttcccaaacagcccatcc ccttttacaccgccaccccctcaaaccccttctcctcatggcacgagaaggcatctgcca tcaccaccactgacacaggaaatggacctccactccattgctgggcctcctgttcctcca cgacaaagcacttctcaacttatccccaaactccctccaaaaacttacaaaagggagcat acacacccatccatgcatagagacggaccacctctgctggagaatgcccattcttcctga

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