Mycolicibacillus parakoreensis: MIU77_07075
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Entry
MIU77_07075 CDS
T07959
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mpak
Mycolicibacillus parakoreensis
Pathway
mpak00300
Lysine biosynthesis
mpak00550
Peptidoglycan biosynthesis
mpak01100
Metabolic pathways
mpak01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mpak00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MIU77_07075 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MIU77_07075 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MIU77_07075 (murF)
Enzymes [BR:
mpak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MIU77_07075 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ULN54035
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Position
1505900..1507411
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AA seq
503 aa
AA seq
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MIALSVAEIAEIVGGRLCDITATRAAQTRVSGTVEFDSRRISAGGLFLALPGARVDGHDH
AAAAVAAGAVAVLAARPVGVPAIVVDPVPGDRRAGVLEHDSDGSGAAVLAALAKLAAAVA
ARLVAGGLTIIGVTGSSGKTSTKDLLAAVLSPLGEVVAPPGSFNNELGHPWTVLNATADT
AYLVLEMSARRRGNIADLAAIAPPSIAVVLNVGTAHVGEFGSREAIAQTKAELPQAVPES
GVVVLNVDDPAVAAMAATTRARVVRVSRGPHPPNPGADTVWAGPVRLDPLARPQFALHSA
AGTVEVTLGVHGDHQVGNALCAAAVALECGATPEQVASALGEARPASAHRMAVHTRPDGV
TVIDDSYNANPDSMRAGLQALAWMARQQAPRRSFAVLGEMAELGADAITEHDRIGRLAVR
LDVSRLIVVGTGRAMSAMHHGAVMEGSWGAESTMVADTDAALAVLRSELQPGDVVLVKAS
NSAGLATVADTLIAEHGGGDSRR
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcgctgagcgtcgccgagatcgccgagatcgtcggtggccggctctgcgacatc
accgcgacgcgagccgcccagacccgcgtcagcggcaccgtggagttcgattcgcgccgg
atctccgccgggggactgtttttggcattgcccggtgcgcgggtcgacggccacgaccac
gccgcggccgcggtcgccgccggtgcggtcgccgtgttggccgcccgcccggtcggtgtg
ccggcgatcgtggtggacccggtgcccggcgaccggcgcgccggggtgctcgaacacgac
agcgatggctcgggggcggcggtgctggccgcgttggcgaaactggccgcggcggtcgcc
gcccgcctggtcgccggcggactgacgatcatcggggtgaccggttcgtcgggcaagacg
tcgaccaaagacctgctggccgcggtgctgtccccgctcggcgaggtggtggcgcccccg
ggatcgttcaacaacgagctgggccacccctggaccgtgctgaacgccaccgccgacacc
gcctatctggtcctggagatgtcggcgcggcgccgcggcaacatcgccgacctggccgcc
atcgcccccccgtcgatcgcggtggtgctcaacgtcggcaccgcccacgtgggcgagttc
ggctcgcgcgaggccatcgcacagaccaaagccgaactgccgcaagctgttcccgagtcc
ggtgtggtcgtgctcaacgtcgacgatccggcggtggcggcgatggccgcgacgacccgg
gcgcgggtggtgcgggtcagccgcggcccgcacccgccgaaccccggcgccgacaccgtg
tgggccggcccggtgcgcctcgacccgctggcccggccgcagttcgccctgcacagcgcc
gccggcaccgtcgaggtcaccctcggggtccacggcgaccaccaggtcggcaacgcgctg
tgcgccgccgcggtcgccctggagtgcggggccacgccggagcaggtggcgagcgcattg
ggcgaggcgcgcccggcctccgcgcaccggatggcggtgcacacccgccccgacggggtg
accgtgatcgacgactcctacaacgccaaccccgactcgatgcgcgccggactgcaggcg
ctggcctggatggcccgtcagcaggctccgcgacgcagtttcgcggtgctcggggagatg
gccgaactcggcgccgacgcgataaccgaacacgatcgcatcggccggttggcggtgcgc
ttagatgtgtctcgacttatcgtcgtcggaaccgggagagctatgagcgccatgcaccac
ggagcggtcatggaaggttcgtggggagcggagtcgaccatggtcgccgacaccgatgcc
gcgttggcggtgctgcgcagcgagttgcagcccggcgacgtcgtgttggtcaaggcctcg
aactcggccgggctggccacggtcgccgacaccttgatcgccgagcacggcggaggggat
tcccgccgatga
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