Microbacterium paraoxydans: IZR02_10310
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Entry
IZR02_10310 CDS
T08796
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mpao
Microbacterium paraoxydans
Pathway
mpao00300
Lysine biosynthesis
mpao00550
Peptidoglycan biosynthesis
mpao01100
Metabolic pathways
mpao01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mpao00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IZR02_10310
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IZR02_10310
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IZR02_10310
Enzymes [BR:
mpao01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IZR02_10310
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
Motif
Other DBs
NCBI-ProteinID:
QXE28794
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Position
complement(2140091..2141503)
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AA seq
470 aa
AA seq
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MIALTLAEIAAAVGGELRVAGEHTPETVVDGIVDTDSRTMEAGSIFVAKPGAETDGHRFV
GAAVEAGAVLAIVERPVDVAVSQIVVSDAVAALGDLAREVVARVRAGGNLRIVGITGSNG
KTTTKNFLARILEDEGETVAPVKSFNNEVGAPVTMLRVTHDTRFLVSEFGAAAPGSIARL
AGLVEPDLVVVLMVGMAHAGGFGGIEATAKAKSELVAAARVPGTAVLNADDARVWAMREL
AESRGLRVVGFGQSAAAAVHARDIEVSASGTQCVIEVAGERLPLRLRVLGAHHVTNALAA
ITAAVELGVAAADAVARLETVEIAERWRMQPLGNDRVRIINDAYNASPDSMAAALRTLAQ
ITGPDERTVAVLGAMSELGESAGEEHDRIGLLAVRLNIRRIVVVGPEARRLYLAAVGEGS
WDSEAVHLPDQDAAFEYLRTELRDGDRVLVKSSNSVGLRHLGDRLGELFS
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccctgacgctcgctgagatcgccgccgccgtcggtggtgagctgcgcgtggcc
ggagagcacacgccggagacggtggtcgacggcatcgtcgacaccgattcccgaaccatg
gaggccgggtcgatcttcgtcgccaagcccggagccgagacggacggacaccgcttcgtc
ggcgccgctgtcgaagccggcgcggtgctggcgatcgtcgagcgtccggtcgacgtcgcg
gtttcacagatcgtcgtctcggatgccgtcgccgcgctcggcgacctcgcccgcgaggtc
gtggcgcgcgtacgcgccggcgggaacctgcgcatcgtcggcatcaccggctccaacggc
aagacgacgacgaagaacttcctcgcccgcatcctcgaggacgagggcgagaccgtcgct
ccggtgaagtccttcaacaacgaggtcggcgccccggtgacgatgctccgcgtcacgcac
gacacccgcttcctcgtgagcgagttcggcgccgccgcgccgggcagcatcgcgcggctc
gccggcctcgtcgagcccgacctcgtcgtcgtgctcatggtcgggatggcgcacgccggg
ggcttcggcggcatcgaggccaccgcgaaggccaagtccgagctcgtcgccgcggcccgc
gtgcccggcacggccgtgctcaacgccgacgacgcccgggtgtgggcgatgcgcgagctc
gcggagagccgcggcctccgggtcgtcggcttcggccagtccgccgcggccgccgtgcac
gcgcgcgacatcgaggtctcggcctccggcacgcagtgcgtgatcgaggtcgcgggggag
cggctgccgctgcggctgcgcgtcctcggcgcgcaccacgtcacgaacgccctcgccgcg
atcaccgcggccgtcgagctcggtgtggccgctgccgacgccgtcgcccgcttggagacc
gtcgagatcgccgagcgctggcgcatgcagcccctgggcaacgaccgcgtccgcatcatc
aacgacgcgtacaacgccagccccgactcgatggcagccgccttgcggaccctcgcccag
atcaccggccccgacgagcgcaccgtcgccgtcctcggcgcgatgagcgagctcggcgag
agcgcgggggaggagcacgaccgcatcggcctcctcgcggtgcgcctcaacatccggcgc
atcgtcgtggtcggcccggaggcccgtcggctgtacctcgccgccgtcggcgagggatcg
tgggacagcgaggccgtgcatctgccggaccaggacgccgcgttcgagtacctccgcacc
gagctgcgcgacggcgaccgggtcctcgtgaagtcgtccaactccgtgggcctccggcat
ctcggcgatcgtctgggagaattgttctcgtga
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