Mycolicibacterium parafortuitum: MPNTM1_00552
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Entry
MPNTM1_00552 CDS
T11082
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mpat Mycolicibacterium parafortuitum
Pathway
mpat00860
Porphyrin metabolism
mpat01100
Metabolic pathways
mpat01110
Biosynthesis of secondary metabolites
mpat01120
Microbial metabolism in diverse environments
mpat01240
Biosynthesis of cofactors
Module
mpat_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mpat_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mpat00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MPNTM1_00552 (hemD)
Enzymes [BR:
mpat01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MPNTM1_00552 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MPNTM1_00552 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
XCI59436
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Position
complement(602153..603841)
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AA seq
562 aa
AA seq
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MSLRGRKGKPGRITFVGSGPGDPGLLTARARAVLANAALVFTDPDVPEAVLTLVGCELPP
PAGPLPAAADKAAKKDADQTDAAAEDAKAAEAAKDAVIPGGPDVRPALGDPAEVAKTLAH
EARTGVDVVRLIAGDPLSVDSVITEINALAKTQLNFEIVPGLPGTSAVPTYAGLPLGSSH
TVADVRGDVDWAALAAAPGPLILHATPSHLPESARTLIEYGLAESTPAVVTANGTTCQQR
SVETTLGGLLDKAVLAGTEPAGPLTGTLVVTIGRTVAHRAKLNWWESRALYGWTVLVPRT
KDQAGEMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRA
VWEKFNEFGLDARAFSGVKIACVGQATADKVRAFGINPELVPTGEQSSLGLLDEFPPYDD
IFDPVNRVLLPRADIATETLAEGLRELGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDA
VCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVEALA
EHAARLRAEGALPPPRKKSRRR
NT seq
1689 nt
NT seq
+upstream
nt +downstream
nt
atgagcttgcgaggacgcaagggcaagcccggacgcatcacattcgtcggctccgggccc
ggagatcccggccttctgacggcgcgggcccgcgcggtgctggccaacgccgccttggtg
ttcaccgaccccgacgtgcccgaagcggtactgacgctggtgggctgcgagttgccgccg
ccggccggaccgctgcccgcggccgccgacaaggcggccaagaaggacgccgaccagacc
gatgccgcggccgaggacgccaaggccgccgaggcggccaaggatgccgtgatccccggt
ggtcccgacgtgcggcccgctctcggcgatccggccgaggtggccaagacgctggcccac
gaggcgcgcaccggggtcgacgtggtccggctcatcgccggtgacccgctgtcggtcgat
tcggtgatcaccgagatcaacgcgctggccaagacccagctgaacttcgagatcgtgccc
ggcctgcccggcacctcggcggtgccgacctacgccgggctgccgctggggtcgtcgcac
accgtcgccgacgtccgtggtgacgtcgactgggcggcgctggccgccgcccccggaccg
ctgatcctgcacgcgacaccgtcgcacctgccggagtcggcccgcaccctgatcgaatac
gggctggccgagtccaccccggccgtggtcaccgccaacggcacgacgtgccagcagcgt
tcggtcgagaccaccctgggcgggctgctcgacaaggccgtgctcgccggtaccgaaccg
gccggtccgctgaccggcacgctggtggtcaccatcggccgcaccgtcgcccaccgcgcc
aagctgaactggtgggaaagccgcgcgctgtacggctggaccgtgctggtgccgcgcacc
aaggaccaggcgggcgagatgagcgaccggctcgtcggacacggcgccctgccgatcgag
gtgccgaccatcgccgtcgaaccgccccgcagccccgcccaaatggaaagggccgtcaag
ggtttggtggacggccggttccagtgggtggtgttcacctcgaccaacgcggtgcgcgcg
gtgtgggaaaagttcaacgagttcggtctcgacgcccgcgcgttctccggggtgaagatc
gcgtgcgtcggtcaggccaccgcggacaaggtgcgcgccttcggcatcaatccggagctg
gtgcccaccggtgagcagagctcgctcggcctgctcgacgaattcccgccctacgacgac
attttcgatccggtgaaccgggtgctgttgccgcgcgccgacatcgcgaccgagacgctg
gccgagggtctgcgcgaactcggttgggagatcgaggatgtcaccgcgtaccggaccgtg
cgcgcggccccgccgccggcgcacacccgcgagatgatcaagaccggcgggttcgacgcg
gtctgcttcacctccagctccacggtgcgcaacctcgtcggtatcgcgggtaagccgcac
gcgcgcaccatcgtcgcgtgcatcggcccgaagaccgccgagaccgcagcggaattcggc
ctccgcgtcgacgtccagcccgaggtggccgccgtcggcccgctcgtcgaggcgctcgcc
gagcatgccgcccggctccgcgccgagggggcgttgccgcccccgcggaagaagagccgc
cgccgctaa
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