Mycolicibacterium phlei: MPHLCCUG_03295
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Entry
MPHLCCUG_03295 CDS
T04305
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mphl
Mycolicibacterium phlei
Pathway
mphl00300
Lysine biosynthesis
mphl00550
Peptidoglycan biosynthesis
mphl01100
Metabolic pathways
mphl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mphl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MPHLCCUG_03295 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MPHLCCUG_03295 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MPHLCCUG_03295 (murF)
Enzymes [BR:
mphl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MPHLCCUG_03295 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMO62099
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Position
complement(3343887..3345386)
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AA seq
499 aa
AA seq
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MIDYTLARIAEIVGGRLTDISAEDAATTRVTGTVEFDSRAVTPGGLFLALPGARADGHDF
AAAAVEAGAVAVLAARPVGVPAIVVDPTPQESDRSAGVLEHDEDGSGAAVLGALARLAAA
VAADLAADGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR
DTRFLVLEMSARHRGNIAALAAIATPSIAVVLNVGTAHLGEFGSREAIAATKAELPQAVP
STGTVVLNVDDTAVAAMAGQTSATVVRVSREPGEKVDVWASGVTLDALARPRFTLHAGDE
SVDVALAVHGDHQVSNALCAAAVALRAGASLRQVADALAAAGPVSKHRMQVTTRADGVTV
INDAYNANPDSMRAGLKALAWMAREGGERRRSWAVLGEMAELGDDAITEHDNIGRLAVRL
DVSRLVVVGTGRTMSAMHHGAVMEGSWGSESTMVPDADAALQLLREELEPGDVVLVKASN
AAGLGALAEALLQDGTARA
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgactacaccctggcccggatcgccgagatcgtcggcggccggctgaccgacatc
tccgccgaggacgccgccaccacccgggtcaccggcaccgtcgagttcgactcgcgcgcc
gtcacccccggcgggctgttcctcgcgctgcccggggcccgcgccgacgggcacgacttc
gccgccgcggccgtcgaggccggtgccgtcgcggtgctggccgcccgtccggtcggggtg
cccgctatcgtcgtcgaccccaccccgcaggagtccgaccgctccgcgggcgtgctggag
cacgacgaggacggctccggtgcggcggtgctgggtgcgctggccaggctggccgccgcc
gtcgccgccgacctcgccgccgacggtctgaccatcgtcgggatcaccggctcgtcgggt
aagacgtcgaccaaggacctcgtcgccgcggtgctggcgccgctcggcgaggtggtcgcc
ccgcccgggtcgttcaacaacgagctcggccacccgtggacggtgctgcgcgccacccgc
gacacccgcttcctggtgctggagatgtcggcgcgccaccgcggcaacatcgccgcgctg
gcggccatcgccaccccgtcgatcgcggtggtgctcaacgtcggcaccgcccacctcggc
gagttcggctcgcgtgaggccatcgccgcgacgaaagccgagctgccgcaagcggttccg
tcgaccggcacggtggtgctcaacgtcgacgacaccgctgtggccgcgatggccgggcag
acgtcggcgacggtggtgcgggtgtcgcgcgaaccgggggagaaggtcgacgtgtgggcc
tccggcgtcacgctcgacgcgctggcccggccgcggttcaccctgcacgccggcgacgag
tccgtcgacgtcgcgctcgccgtgcacggcgaccaccaggtgtccaacgcgctgtgcgcg
gccgccgtggcgctgcgcgccggggcctccctgcggcaggtggccgacgcgctggccgcc
gccgggccggtgtccaagcaccgcatgcaggtcaccacccgcgccgacggcgtcaccgtg
atcaacgacgcctacaacgccaaccccgactcgatgcgcgccgggctgaaggcgctggcc
tggatggcccgggagggcggtgagcgccgccgcagctgggcggtgctcggcgagatggcc
gaactcggcgacgacgcgattaccgaacatgacaacatcggtcgactggcggtgcgatta
gatgtgtcacgactcgtcgtcgtcggaaccgggaggactatgagcgccatgcaccacggc
gccgtgatggagggatcgtgggggtcggagtccaccatggttcccgacgccgacgcggct
ctgcagctgctgcgcgaggagctggagccgggtgacgtcgtgctggtgaaggcctccaac
gccgccgggctgggcgcgctggccgaagccctgctccaagacgggaccgcgcgggcatga
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