Mycolicibacterium phlei: MPHLCCUG_03601
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Entry
MPHLCCUG_03601 CDS
T04305
Symbol
fgs
Name
(GenBank) Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mphl
Mycolicibacterium phlei
Pathway
mphl00790
Folate biosynthesis
mphl01100
Metabolic pathways
mphl01240
Biosynthesis of cofactors
Module
mphl_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
mphl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MPHLCCUG_03601 (fgs)
Enzymes [BR:
mphl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MPHLCCUG_03601 (fgs)
6.3.2.17 tetrahydrofolate synthase
MPHLCCUG_03601 (fgs)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AMO62402
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Position
complement(3665574..3666995)
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AA seq
473 aa
AA seq
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MTDPAADGAPTPDEIASLLQVEHLLDQRWPETKLEPSTTRIVALLEMLGSPQRAYPSIHI
AGTNGKTSVARMIDALLTALHRRTGRTISPHLQSAVERISIDGVPISPARYVETYREIEP
FVEMVDAQSQAAGGPAMSKFEVVTAMAFAAFADAPIDVAVVETGLGGRWDATNVVNAPVA
VITPIGMDHADYLGDTIADIAGEKAGIITKQEDDLVPTDTVAVIGRQPPEAMEVLLAQAV
RADAAVARQDHEFTVLARQIAVGGQMLELQGLGGVYSEIFLPLHGEHQAHNAALALAAVE
AFFGAGAQRQLDVDAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGAAALAQTLQEEF
DFRFLVGVVSVMADKDVAGILTALEPVFDQIVVTHNGSPRAMDVEGLALLAEEQFGPERV
ATAATLPDAIETATAIFEESAAEGESFGGAGVVITGSVVTAGAARTLFGKDPQ
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccggcggcagacggcgccccgacgcccgacgagatcgcgtcgctgctgcag
gtcgagcacctgctcgaccagcgctggcccgagaccaagctcgaacccagcaccacccgg
atcgtggcgctgctggagatgctcggctcaccgcagcgcgcatacccgtcgatccacatc
gccggcaccaacggcaagacgtcggtggcccgcatgatcgacgcgctgctgaccgcgctg
caccggcgcaccggtcgcaccatcagcccgcacctgcagtccgccgtcgaacgcatctcg
atcgacggcgtcccgatcagcccggcgcgctacgtggagacctaccgcgagatcgagccg
ttcgtggagatggtcgacgcgcagtcgcaggcggcaggcggcccggcgatgagcaagttc
gaggtggtcaccgcgatggcgttcgccgccttcgccgacgcgccgatcgacgtcgccgtc
gtcgagaccggcctcggcggacgttgggacgcaacgaatgtcgtcaacgcgccggtcgcg
gtgatcaccccgatcgggatggatcacgccgactacctcggcgacaccatcgccgacatc
gcgggggagaaggccggcatcatcaccaaacaggaagacgacctggtgcccaccgacacc
gtcgcggtcatcggccgccagccaccggaggcgatggaggtgctgctggcgcaggcggtg
cgcgccgacgccgcggtggcccgccaggaccacgagttcacggtgctggcccgccagatc
gccgtcggcggtcagatgctggagctgcagggcctcggcggcgtctacagcgagatcttc
ctgccgctgcacggcgagcaccaggcccacaacgccgcgctcgcgctggccgcggtggag
gcgttcttcggcgccggtgcgcagcgccaactcgacgtcgacgccgtgcgcgccggtttc
gccgcggtgaccagtcccggccgcctggagcggatgcgcagtgcgccaacagttttcatc
gacgccgcgcacaacccggcgggggcggcggcgctggcgcagacgctgcaggaggagttc
gacttccggttcctcgtcggtgtggtgtcggtgatggccgacaaggacgtcgcgggcatc
ctgactgcgctcgagcccgtgttcgaccagatcgtggtcacccacaacgggtcaccgcgc
gccatggacgtcgaggggctggcgctgctggccgaggagcagttcggccccgagcgggtg
gccaccgcggcaaccctgccggatgcgatcgagaccgccaccgcgatcttcgaggagtcc
gccgccgagggtgagtcgttcggcggcgcgggtgtggtgatcaccggctccgtcgtcacc
gccggcgccgcgcgcacgctgttcggaaaggatccgcaatga
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