Mycolicibacterium phocaicum: MPHO_15140
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Entry
MPHO_15140 CDS
T07283
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mphu
Mycolicibacterium phocaicum
Pathway
mphu00290
Valine, leucine and isoleucine biosynthesis
mphu00660
C5-Branched dibasic acid metabolism
mphu01100
Metabolic pathways
mphu01110
Biosynthesis of secondary metabolites
mphu01210
2-Oxocarboxylic acid metabolism
mphu01230
Biosynthesis of amino acids
Module
mphu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mphu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MPHO_15140 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MPHO_15140 (leuC)
Enzymes [BR:
mphu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MPHO_15140 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MPHO_15140 (leuC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BBZ54522
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All DBs
Position
complement(1533140..1534564)
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AA seq
474 aa
AA seq
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MTNKPRTMAEKVWADHVVVEGAGEGAAREPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVH
RPDLTIATEDHNVPTIDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDAQQGIVHIIG
PQLGLTQPGMTVVCGDSHTSTHGAFGAIAMGIGTSEVEHVLATQTLPLKPFKTMAVNVDG
ELPPGVSAKDIILAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGM
VAPDETTFEFLKGRPHAPQGADWDAAVAAWTALRTDEGAEFDTEVHIDAATLSPFVTWGT
NPGQGVPLSANVPDPEQMFDEGDRLAAEKALAYMDLRANTPMRDIAVDTVFVGSCTNGRI
EDLRVVADVLRGRKIADGVRMLVVPGSMAVRAQAESEGLGEVFTAAGAEWRQAGCSMCLG
MNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLS
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgacgaacaagccacgcaccatggcggagaaggtctgggcggaccatgtggtggtcgag
ggtgccggtgaaggcgccgcccgcgaacccgatctcatctatatagaccttcatctggtg
cacgaggtcaccagcccgcaggcattcgacggcctgcgcctggccggtcgtcccgtccat
cgcccggacctcaccatcgcgaccgaggaccacaacgtccccacgatcgacatcgacaag
ccgatcgcggatccggtgtcccgcactcaggttgagacgctgcggcgcaactgtgcggaa
ttcggcatccgcctgcacccgatgggtgacgcgcagcagggcatcgtgcacatcatcgga
ccgcagctgggtctgacccagcccggtatgacggtggtgtgtggtgacagccacacctcg
acgcacggtgccttcggcgcgatcgcgatgggcatcggcacgtccgaggtcgagcatgtg
ctggcgacccagacgttgccgctcaagccgttcaagaccatggcggtcaatgtcgacggc
gaactgccaccgggagtcagtgccaaggacatcattctcgcggtgatcgccaagatcggt
accggcggcggccagggtcacgtcatcgaataccgcggcagtgccatcgaatcgctgtcg
atggaaggccgcatgacgatctgcaacatgagcatcgaagcgggtgcccgcgccggcatg
gtggcgcccgacgagacgacgttcgagttcctcaagggccgtccgcatgcgccgcagggg
gcggattgggacgcggccgtggcggcctggacggcgttacgtactgacgagggtgccgaa
ttcgacaccgaggtgcacatcgacgcggccaccctgagcccgttcgtcacctggggtacc
aaccccgggcagggcgtgccgctgtccgcgaatgtccctgacccagaacaaatgttcgat
gaaggtgaccggctggccgccgaaaaggcgttggcctacatggaccttcgggccaatacg
cccatgcgggacatcgcggtggacaccgtgttcgtcggttcctgcaccaacggccggatc
gaagatctgcgggtggtggccgatgtgctgcgtggccgcaagatcgccgacggcgtgcgg
atgctcgtggtgcccgggtcgatggcggtgcgtgcacaggccgaatccgagggtctggga
gaggttttcaccgccgccggcgccgagtggcggcaggccggctgctcgatgtgtctgggc
atgaaccccgaccagctggctccgggcgagcgcagcgcctccacatccaaccggaatttc
gaaggccgccaaggcaagggcggccgcacccacctggtgtctcccgccgtcgccgccgcc
accgcggtgcgcggaaccctgtcctcacccgctgatctgagctag
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