Methylobacterium phyllosphaerae: MCBMB27_01978
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Entry
MCBMB27_01978 CDS
T04968
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mphy
Methylobacterium phyllosphaerae
Pathway
mphy00300
Lysine biosynthesis
mphy00550
Peptidoglycan biosynthesis
mphy01100
Metabolic pathways
mphy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mphy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MCBMB27_01978
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MCBMB27_01978
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MCBMB27_01978
Enzymes [BR:
mphy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MCBMB27_01978
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
APT31269
UniProt:
A0AAE8HT90
LinkDB
All DBs
Position
complement(2111903..2113351)
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AA seq
482 aa
AA seq
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MTALWTREELESATGGRLIGPERAIGGASIDTRTLQPGDLFFAIRGDARDGHDFVPDALG
RGAGAAVVSASRLGDLASHGPVLTVPEAGADPVLTAMVRLGAAARARTGAQVVAVTGSVG
KTGTKEALRHVLAEQGETHASAASYNNHWGVPLTLARMPRSTRYGVFEIGMNHGGEIVPL
TAQVRPDIALITTIAPAHIEHFLSLAAIADAKGEIFSGIQPGGVAIVNRDVPHFDRLAAH
AQASRAGRVVTFGEHPESDVRALKIVLRPDLSVIDAAVMGQPVTYKLGTAGRHAALNSLG
VMAVVHSLGADLARAALSLGSLTPPAGRGERTALEIGGGTAYLVDESYNANPVAVRAALA
TLAGIETGPRGRRIAVLGDMLELGAAAPDLHRGLAEAIEAARIDLVFTAGPLMRHLFEAL
PVSRRGAVTDTAADLLEPLARNLRSGDVVMVKGSNGSRMGRIVEALKARYAVDPTRRTQA
VP
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcactctggacgcgggaggagctggaatccgcgacgggcggccgactgatcggc
cccgagcgcgccatcggcggcgcctcgatcgacacccgcacgctccagcccggcgacctg
ttcttcgcgatccgcggcgatgcacgcgacggccacgacttcgttcccgacgccctgggc
cgcggggccggcgccgcggtggtgagcgcgtcccgcctcggggacctcgcgtcccacggt
cccgtcctgacggtgcccgaagcgggcgccgacccggtactcaccgcgatggtgcgtctc
ggcgccgccgcccgcgcccggacaggcgcgcaggtcgtggccgtcaccggctcggtcggc
aagaccgggaccaaggaggcgctgcgccacgtcctggccgagcagggggagacccacgcc
tcggcggcctcctacaacaatcattggggcgtgcccctgaccctggcgcggatgccgcgc
tccacgcgctacggcgtgttcgagatcggcatgaaccacggcggcgagatcgtgccgctg
accgcccaggtccgccccgacatcgcgctcatcaccaccatcgcgcccgcccatatcgaa
catttcctctcgctcgccgccatcgcggacgccaagggcgagatcttctccgggatccag
cccggcggcgtggcgatcgtcaaccgcgacgttccgcatttcgaccggctcgcggcccac
gcgcaggcctcccgggcgggacgggtcgtcaccttcggcgagcacccggaatccgacgtg
cgcgccttgaagatcgtgctccgccctgacctgtcggtgatcgacgcggcggtgatgggc
cagcccgtcacctacaagctcggcacggccggacggcacgcggcgctgaactcgctcggc
gtcatggcggtggtccacagcctcggggccgacctcgcccgcgccgccttgtctctgggc
agcctgacgccgccggcgggccgcggcgagcgcaccgccctcgagatcggtggcggcacc
gcctacctcgtggacgagagctacaatgccaaccccgtcgcggtccgcgcggcgctggcg
acgctcgccgggatcgagaccggaccccgcggacgccggatcgcggtgctgggcgacatg
ctggaactcggcgccgccgcgcccgacctgcaccgcggcctcgcggaggcgatcgaggcg
gcacggatcgacctcgtcttcacggccggtccgctgatgcgccacctgttcgaggccctg
ccggtgagccgccgcggcgccgtgaccgacaccgccgccgacctgctcgagccgctcgcc
cggaatctcagatccggcgacgtcgtcatggtaaaaggatcgaacggcagccgcatgggc
cggattgtcgaggcgctgaaagcccgctacgcggtcgatccgacccggcggacccaggcc
gtcccgtga
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