Methylorubrum populi: Mpop_5176
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Entry
Mpop_5176 CDS
T00760
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mpo
Methylorubrum populi
Pathway
mpo00300
Lysine biosynthesis
mpo00550
Peptidoglycan biosynthesis
mpo01100
Metabolic pathways
mpo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mpo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Mpop_5176
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Mpop_5176
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Mpop_5176
Enzymes [BR:
mpo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Mpop_5176
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACB83270
UniProt:
B1Z8X0
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Position
complement(5542797..5544260)
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AA seq
487 aa
AA seq
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MSDAPLWTPAALESATGGRLIGAPRAVTGASIDTRSLEPGDLFFAIRGEARDGHDFVRAA
LEKGAGAAVVAAARANEFEGVGPVLAVPGEDEDPVLEAMRRLGLAARARTGAAIVAVTGS
VGKTGTKEALRHVLSAQGATHASVASYNNHWGVPLTLARMPEQTRFGVFEIGMNHGAEIL
PLTAMVRPDVALITTVEPVHIEHFRSLSAIADAKGEIFSGLKPGGVAVINRDNPNYERLL
AHAHASRAGRVITFGEHAAADVRANRILTRPDVSVVDASVMGVPLTYQLGTPGRHVAMNS
LGVLACIHALGADLARAALSLAALKPPVGRGERTALRVGDGEAFLIDESYNANPASIRAA
LATLAGIETGAKGRRIAVLGDMKELGAAGETHHRELADAVAGHGIDVVFAVGPLMAHLFE
ALPMAVRGTAAPSAEGVTDAVLATLRPGDAVMVKGSNSMRMVRIVEAVKARYAVAPDPRE
ASLNAVR
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacgcccccctctggacgccggctgccctggagtccgccaccggcgggcgcctg
atcggcgcgccccgcgccgtcaccggtgcgtcgatcgacacccgcagcctggagcccggc
gacctgttcttcgccatccgcggcgaggcgcgggacgggcacgacttcgtgcgtgccgcc
ttggagaagggcgccggcgcagcggtggtcgcggccgcgcgtgcgaacgagttcgagggc
gtcggcccggtgctggcggtgccgggggaggacgaggatccggttctggaggcgatgcgc
cgcctcgggctcgccgcccgcgcccgcaccggggccgccatcgtcgcggtcacgggttcg
gtcggcaagaccggcaccaaggaggccctgcgccacgtgctctcggcccaaggcgccacc
cacgcctcggtcgcctcctacaacaaccactggggcgtgccgctgacgctggcgcggatg
ccggaacagacccgcttcggcgtgtttgagatcggcatgaatcacggcgccgagatcctg
ccgctcaccgcgatggtgcggccggacgtggcgctgatcacgacggtcgagccggtccat
atcgagcattttcgctcgctctcggccatcgccgacgccaagggcgagatcttttccggg
ctcaagcccggcggtgtcgcggtgatcaaccgcgacaacccgaattacgagcggctgctg
gctcacgcccacgcctcgcgggccggacgcgtcatcaccttcggcgagcatgcggcggcg
gatgtgcgggcgaaccggatcctgacccggcccgatgtctcggtggtcgatgccagcgtg
atgggcgtgcccctgacctatcagctcggcacgccgggccggcacgtggcgatgaactcg
ctcggcgtgctcgcctgcatccacgcgctcggtgccgacctcgcccgcgccgccctgtcg
ctcgccgcgctgaagccgccggtcgggcgcggcgagcgcaccgccctgcgggtcggggac
ggcgaagccttcctgatcgacgagagctacaacgccaaccccgcctcgatccgcgccgcc
ctggcgacgcttgccggcatcgagaccggcgccaagggccggcgcatcgccgtgctcggc
gacatgaaggagctcggcgcggccggcgagacgcaccaccgcgaactggcggatgcggtc
gcgggccatggcatcgacgtcgtcttcgccgtcggcccgctgatggcgcacctgttcgag
gccctgccgatggcggtgcggggcacggccgcgccgagcgcggagggcgtcaccgacgcc
gtcctcgcgaccctgcggccgggcgatgcggtgatggtcaagggctccaactccatgcgc
atggtccgcattgtcgaagcggtcaaagcccgctacgcggtcgcgccggacccgcgcgaa
gcctcgctgaacgcggtccgctga
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