Micromonospora profundi: Q3V37_12520
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Entry
Q3V37_12520 CDS
T09358
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mprn
Micromonospora profundi
Pathway
mprn00280
Valine, leucine and isoleucine degradation
mprn00640
Propanoate metabolism
mprn00785
Lipoic acid metabolism
mprn01100
Metabolic pathways
mprn01110
Biosynthesis of secondary metabolites
mprn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mprn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Q3V37_12520
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Q3V37_12520
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Q3V37_12520
Enzymes [BR:
mprn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Q3V37_12520
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
DUF6409
Motif
Other DBs
NCBI-ProteinID:
WLS47977
UniProt:
A0AAJ6HWU7
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Position
complement(2708837..2709988)
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AA seq
383 aa
AA seq
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MSTSNIVRSPAGSSTPSPANPFTSTADLPRAPDGFIQFIAPDGQLRTDTDVDRDALGRLT
RDLYRGMRLARRLDDEAFALQRQGELGLWLQCRGQEAAQVGSIAAVRADDYVFPSYREHA
AALWRGIRPADLLRQWRGVANSGWDPEPYSFHIYTLVLAAQLLHATGYALGVQRDGSDTV
VVAYFGDGAASEGDASEAMNIAATNDAPVLFFCQDNHWAISTASSSQSRTPIHRRGAGFG
LRSEWVDGNDVLAVYAVTSALTEHVRSGGGPALIEATTYRMGGHSTSDDPTRYRTDSELE
AWRAKDPLARVEALLRAEGWSDTAFLDEIQAEADELADRTRRECLALQAPDLADAFATVL
ADVPQLLQEEHDAFVAYRDSFLD
NT seq
1152 nt
NT seq
+upstream
nt +downstream
nt
ttgagtacctcgaacatcgtcaggtcacccgccggcagctcgacgccctcccccgccaat
cccttcaccagcaccgccgaccttccgcgagccccggacggcttcatccagttcatcgcc
ccggacgggcaactacgcacggacaccgacgtcgaccgcgacgccctcggcaggctcacc
cgcgacctgtaccgcggtatgcggctcgcacgccgcctcgacgacgaggcgttcgcgttg
cagcgacagggcgagctgggcctgtggttgcagtgccgcggccaggaggccgcacaggtc
ggctccatagctgcggtacgcgccgacgactacgtcttcccgagctaccgcgagcacgcc
gccgccctgtggcgcggcatccgccccgcggacctgctccggcagtggcgtggggtcgcc
aacagcggctgggaccccgagccgtactcgttccacatctacaccctggtcctggcagct
cagttgctgcacgccaccgggtacgccctgggggtgcagcgcgacggcagcgacacggtg
gtcgtggcgtacttcggtgacggcgccgccagcgagggcgacgcgagcgaggcgatgaac
atcgccgccaccaacgacgcgccggtcctgttcttctgccaggacaaccactgggcgatc
tcgactgcctcgtcgtcccagtcgcgcacgccgatccaccggaggggggccgggttcggt
ctgcgcagcgagtgggtcgatggcaacgacgtcctcgccgtgtacgccgtgacgtccgcg
ctgaccgaacacgtgcgctccggcggcgggcccgcgctcatcgaggccaccacgtaccgg
atgggcgggcacagcacgtccgacgaccccacgcggtaccgcaccgacagcgaactcgaa
gcgtggcgggcgaaggatccgttggcgcgcgtcgaagcacttctgcgcgccgagggctgg
agcgacacggcgttcctcgacgagatccaggccgaggcggacgaactcgccgaccgcacg
cgccgggaatgcctggcactgcaggcgccggacctcgcggacgccttcgccactgtgctg
gccgacgtaccacaactgcttcaggaggagcacgacgcgttcgtcgcctaccgcgactct
ttcctcgactga
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