Micromonospora profundi: Q3V37_14545
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Entry
Q3V37_14545 CDS
T09358
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mprn
Micromonospora profundi
Pathway
mprn00280
Valine, leucine and isoleucine degradation
mprn00640
Propanoate metabolism
mprn00785
Lipoic acid metabolism
mprn01100
Metabolic pathways
mprn01110
Biosynthesis of secondary metabolites
mprn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mprn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Q3V37_14545
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Q3V37_14545
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Q3V37_14545
Enzymes [BR:
mprn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Q3V37_14545
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
PFOR_II
Transketolase_C_1
Motif
Other DBs
NCBI-ProteinID:
WLS48340
UniProt:
A0AAJ6I0F1
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All DBs
Position
3145230..3147788
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AA seq
852 aa
AA seq
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MLCDVTTPQDLDDRFRETLAALPAAQRRRDAADPVTDDAPLTGAQLLDLFDAQVTSRQLD
LAGRWLRSFGEGFYTIGSAGHEGNAAVAAALRPTDPALLHYRSGAFYCVRAAQAAADAPP
TSTVEPGSTVEPTSAAGPDSAARPTSTVAPASSTDLRSSTEPPSGAAPSTAGEPTAGAES
AEAAEGEPAGSTPPGGFEAYAEAARDVLRGMVASSQEPIAGGRHKVFGRADLAIVPTTST
IASHLPRAVGMGLAVERLRRMDSAGRRTGAGAQVGGAENAPWPPDAIVVCSFGDASVNHA
SATAAFNTAGWYDHAGLRIPVLFVCEDNGLGISVRSPKGWVEATLRSKPGIRYFSADGAD
PVGTYAAAAEAAAWVRRHRRPAVLHLHTVRLMGHAGADAESAYRSPAELADDVARDPVAA
TARLLVEAGVATGDELLARYDETGWQIRRLAEDVLGEPKLASAAEVVSALAPRRPVRVAR
AVADAAARASGPGAGARAEAFGGKPPELAGPLTLAQSINAALADGMLDHPRMAVFGEDVA
AKGGVYGVTKGLRDRFGAARVFDTLLDETSVLGLGLGAGLAGMLPVPEIQYLAYLHNAED
QLRGEAATMQFFSQGAFRNPMVVRVAGLAYQEGFGGHFHNDNSVSVLRDVPGLVIAVPAR
PDDAAPMLRTCLASAAVDGSVCVFLEPIALYHTRDLYADGDGEWLAGYPEPGSWVTGHVP
IGRARVYQVGSADDLTIITFGNGVRMSLRAAAALAEEGVGTRVVDLRWLAPLPVADIIRE
SSATGRVLVVDETRRSGGVGEGVIAALVDAGYVGAARRVAGVDSFVPLGPAARQVLVSAE
AITEGARTLLAR
NT seq
2559 nt
NT seq
+upstream
nt +downstream
nt
atgctgtgcgacgtgaccaccccgcaagatctcgacgaccgcttccgggagacgctggcg
gcacttcccgccgcgcaacgccggcgtgatgccgccgacccggtcaccgacgacgcccca
ctgaccggcgcgcaactgctcgacctgttcgacgcgcaggtcaccagcaggcagctcgac
cttgccggtcgttggctacgcagcttcggagagggcttctacacgatcggttcggctggg
cacgagggcaacgccgcggtcgccgccgcgctacgccccaccgacccggcgttgctgcac
taccgctccggggctttctactgcgtgcgcgccgcccaggccgccgccgacgcaccaccg
acgtccaccgtcgagccaggctccaccgtagagccgacctccgctgccgggcccgactcc
gctgccaggcccacctccaccgtcgcgcctgcctccagcacggatctgcggtccagtacc
gagccgccgtccggcgccgcgccgtcgaccgctggggagccgacggccggcgcggaatcg
gccgaggccgccgagggggagccggcgggatccacgccgcccggtggcttcgaggcgtac
gcggaggcggcccgggacgtactgcgggggatggtcgcctccagccaggagccgatcgcc
ggcgggcggcacaaggtgttcggccgggccgacctggccatcgtgccgaccacgtccacc
atcgcctcgcacctgccccgggcggtcgggatggggctggccgtggagcggctgcgccga
atggacagtgcgggtcggcgtaccggggcgggggctcaggtgggcggtgccgagaacgcg
ccgtggccgccggacgccatcgttgtctgttcttttggtgacgcgtcggtcaaccacgcc
agtgccaccgccgccttcaacacagccggctggtacgaccacgcggggctgcgcatcccg
gtgctcttcgtctgcgaggacaacgggctgggcatcagcgtccgctccccgaagggctgg
gtggaggcgacgctgcggtccaagccgggcatccgctacttcagcgccgacggcgcagat
ccggtgggtacgtacgcggcggcggccgaggcggcagcctgggtacgccgacaccggcga
ccggcagtgctgcacctgcacaccgtccggctgatggggcacgcaggggcggacgccgaa
tcggcgtaccgaagcccggccgaactcgccgacgacgtggcccgggatccggtggccgcc
accgcccggctgctcgtcgaggcgggcgtggcgacgggcgatgagctgttggcccggtac
gacgagaccggctggcagatccgccggctcgccgaggacgtgttgggtgagccgaagctg
gcctccgcagccgaggtggtgtcggcgctggcgccgcgccgcccggtgcgggtggcacgg
gcggtggccgacgcggccgcgcgggccagcgggcccggcgcgggtgcccgcgcggaggcg
ttcgggggcaagccgccggagctggccgggccgctgaccctggcgcagagcatcaacgcg
gcgctcgccgacgggatgctcgaccacccgcggatggccgtcttcggtgaggacgtggcc
gccaagggtggcgtgtacggggtgacgaagggtctgcgcgaccgcttcggagcggcacgg
gtcttcgacaccctgctcgacgagacgtcagtgctcgggctcgggctgggcgcagggctg
gccgggatgctgccggtgccggagatccagtacctggcgtacctgcacaacgccgaggac
cagctgcgcggcgaggccgccaccatgcagttcttctcgcagggggcgttccgcaacccg
atggtggtccgggtggcggggctggcgtaccaggaggggttcggcgggcacttccacaac
gacaactcggtgtccgtactccgggatgtgcccggtctggtgatcgcggtgccggcgcgg
ccggacgacgccgcgcccatgctgcggacctgcctggcaagcgcggccgtggacggcagc
gtctgcgtcttcctggagccgatcgcgctctaccacacccgcgacctgtacgccgatggc
gacggggagtggctggccggctatcccgagccgggctcgtgggtgacggggcacgtgccg
atcggccgggcgcgggtctaccaggtcggttcggccgacgacctcacgatcatcaccttc
ggaaacggggtacggatgtcgctgcgagcggcggccgccctcgccgaggagggggtgggt
acgagggtcgttgacctgcggtggcttgctccgctgccggtggccgacatcatcagggag
tcctcggcgaccggccgcgtgctcgtggtggacgagacacgccgatccggtggggtcggc
gaaggtgtgatcgccgcgcttgtcgacgccggatatgtcggtgcggcgcgtcgagtagcc
ggagttgactcgtttgtaccattaggtccggcagcacgccaggttctggtctccgcggaa
gccattaccgagggtgcccgtacgctgctggcacggtaa
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