Micromonospora profundi: Q3V37_15910
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Entry
Q3V37_15910 CDS
T09358
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mprn
Micromonospora profundi
Pathway
mprn00300
Lysine biosynthesis
mprn00550
Peptidoglycan biosynthesis
mprn01100
Metabolic pathways
mprn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mprn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Q3V37_15910 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Q3V37_15910 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Q3V37_15910 (murF)
Enzymes [BR:
mprn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Q3V37_15910 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WLS42932
UniProt:
A0AAJ6HMU9
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Position
3483558..3484955
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AA seq
465 aa
AA seq
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MIALSLAEVAEAVQGRLVAADPTATVTGPVEFDSRKVGAGSLFVAFPGEKVDGHDYADTA
MAAGAVAVLGTREVPGVPMVLVDDALAAMGRLARAAVDRLPELTVIGVTGSSGKTTTKDL
IGQLTTRLGATVAPPGSFNNELGHPYTALQADPGTRYLVMEKGARGIGHVRYLCELVPPR
ISVVLNVGTSHIGEFGSQDAIAQAKGELVEALPPDGLAVLNADDPRVSAMASRTRARVVR
YGEAADADVRAEDVTLDERGHPSYTLVTSEGRAPVRLGLTGRHQVGNTLAAAAVARELGM
PLAELATALGELVLVSTRRMDVFDRPDGVTVIDDSYNANPASMAVALRALASLGEGRRTV
AVLGYMAELGPFERDGHLEVGRLAAELGVNRLLVVGEPAAPIHEGATAVANWGGESVLLT
DQAAAVEVLRSELRPGDVVLVKGSRYRTWEVVDALRADAAGESTR
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccctgagcctggccgaggtggccgaggcggtgcaggggcggctcgtggccgcc
gacccgaccgccacagtcaccggccctgtcgagttcgactcgcgcaaggtgggggccgga
tcgctcttcgtggcgttccccggtgagaaggtcgacgggcacgactacgccgacacggcg
atggcggcgggcgcggtggcggtgctcggcacccgcgaggtgcccggcgtgccgatggtg
cttgtcgacgacgcgctcgccgcgatgggccggctggcccgtgccgctgtcgaccggctg
cccgagctgacagtgatcggcgtgaccggctcgtcgggcaagaccaccacgaaggacctg
atcgggcagctcaccacccggctcggggccactgtggcgccgcccggctcgttcaacaac
gagcttgggcacccgtacacggccttgcaggccgacccgggcacccgctacctggtgatg
gagaagggcgcccgtgggatcgggcacgtgcgctacctgtgcgagctggtgccgccccgg
atctcggtggtgctcaacgtcgggacgtcgcacatcggcgagttcggctcccaggacgcc
atcgcgcaggccaagggcgaactggtcgaggcgctgccgcccgacgggctggccgtcctc
aacgccgacgacccacgggtgtccgccatggcgagccgcacccgggcacgggtggtgcgt
tacggcgaggcggcggacgccgacgtacgggccgaggacgtcacgctcgacgagcgcggg
cacccgtcgtacacccttgtgacgtcggaggggcgcgcgccggtacggctcgggttgacc
ggccgccaccaggtcggcaacaccctcgccgccgcagcggtcgcccgggagttgggcatg
ccgctcgccgagctggccacggcgctcggcgagctggtgttggtctcgacccggcggatg
gacgtcttcgacaggcccgacggggtcactgtcatcgacgactcgtacaacgccaacccg
gcctcgatggctgtcgcgctgcgggcgcttgccagcctcggcgaggggcggcgtaccgtc
gcggtgctcggttacatggccgagctgggcccgttcgagcgcgacggccaccttgaggtc
ggccgactcgcggccgagttgggcgtcaaccggctgctcgtggtgggtgagccggccgcg
ccgatccacgaaggcgcgacagcggtagcgaactggggaggagagtcggtgctgctcacc
gatcaggcggcggccgtcgaggtgctgcggagcgagttacggccgggcgatgtcgtcctg
gtcaagggctcccggtatcggacctgggaggtggtcgacgcgctgcgcgccgacgccgcc
ggggaatccacccgatga
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