Mustela putorius furo (domestic ferret): 101670617
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Entry
101670617 CDS
T07239
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf00562
Inositol phosphate metabolism
mpuf01100
Metabolic pathways
mpuf01521
EGFR tyrosine kinase inhibitor resistance
mpuf04012
ErbB signaling pathway
mpuf04014
Ras signaling pathway
mpuf04020
Calcium signaling pathway
mpuf04062
Chemokine signaling pathway
mpuf04064
NF-kappa B signaling pathway
mpuf04066
HIF-1 signaling pathway
mpuf04070
Phosphatidylinositol signaling system
mpuf04072
Phospholipase D signaling pathway
mpuf04360
Axon guidance
mpuf04370
VEGF signaling pathway
mpuf04380
Osteoclast differentiation
mpuf04611
Platelet activation
mpuf04613
Neutrophil extracellular trap formation
mpuf04625
C-type lectin receptor signaling pathway
mpuf04650
Natural killer cell mediated cytotoxicity
mpuf04662
B cell receptor signaling pathway
mpuf04664
Fc epsilon RI signaling pathway
mpuf04666
Fc gamma R-mediated phagocytosis
mpuf04670
Leukocyte transendothelial migration
mpuf04722
Neurotrophin signaling pathway
mpuf04750
Inflammatory mediator regulation of TRP channels
mpuf04919
Thyroid hormone signaling pathway
mpuf04933
AGE-RAGE signaling pathway in diabetic complications
mpuf04935
Growth hormone synthesis, secretion and action
mpuf05167
Kaposi sarcoma-associated herpesvirus infection
mpuf05169
Epstein-Barr virus infection
mpuf05170
Human immunodeficiency virus 1 infection
mpuf05171
Coronavirus disease - COVID-19
mpuf05200
Pathways in cancer
mpuf05205
Proteoglycans in cancer
mpuf05206
MicroRNAs in cancer
mpuf05214
Glioma
mpuf05223
Non-small cell lung cancer
mpuf05225
Hepatocellular carcinoma
Module
mpuf_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101670617 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101670617 (PLCG2)
04014 Ras signaling pathway
101670617 (PLCG2)
04370 VEGF signaling pathway
101670617 (PLCG2)
04064 NF-kappa B signaling pathway
101670617 (PLCG2)
04066 HIF-1 signaling pathway
101670617 (PLCG2)
04020 Calcium signaling pathway
101670617 (PLCG2)
04070 Phosphatidylinositol signaling system
101670617 (PLCG2)
04072 Phospholipase D signaling pathway
101670617 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101670617 (PLCG2)
04613 Neutrophil extracellular trap formation
101670617 (PLCG2)
04625 C-type lectin receptor signaling pathway
101670617 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
101670617 (PLCG2)
04662 B cell receptor signaling pathway
101670617 (PLCG2)
04664 Fc epsilon RI signaling pathway
101670617 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
101670617 (PLCG2)
04670 Leukocyte transendothelial migration
101670617 (PLCG2)
04062 Chemokine signaling pathway
101670617 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
101670617 (PLCG2)
04919 Thyroid hormone signaling pathway
101670617 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101670617 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101670617 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
101670617 (PLCG2)
04380 Osteoclast differentiation
101670617 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101670617 (PLCG2)
05206 MicroRNAs in cancer
101670617 (PLCG2)
05205 Proteoglycans in cancer
101670617 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101670617 (PLCG2)
05214 Glioma
101670617 (PLCG2)
05223 Non-small cell lung cancer
101670617 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101670617 (PLCG2)
05171 Coronavirus disease - COVID-19
101670617 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
101670617 (PLCG2)
05169 Epstein-Barr virus infection
101670617 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101670617 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101670617 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mpuf04131
]
101670617 (PLCG2)
Enzymes [BR:
mpuf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101670617 (PLCG2)
Membrane trafficking [BR:
mpuf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101670617 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
101670617 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
SH2_1
PH
SH3_2
GDPD
Motif
Other DBs
NCBI-GeneID:
101670617
NCBI-ProteinID:
XP_012912332
LinkDB
All DBs
Position
Unknown
AA seq
1101 aa
AA seq
DB search
MAHIPGSSKRQIPGPSQAGASQPLLVSSVAGGVVSVTLCPQRASQGVWWQLLWLVFCLNT
LLFPEDSNTDRPDASAVYLHDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPF
LFVDEFLTYLFSRENSIWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEA
YIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILS
IEEHCCVEQQRHMARVFKEVFGDQLLTKPTEASADQLPSPSQLREKFIIKHKKLGPRGDV
DVNMEDKKDEHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPT
ELHFGEEWFHKKVEKRTSAERLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQ
HCRIRSTMEGGTMKYFLTDNVTFTSIYDLIQHYRETHLRCTEFELRLTDPVPNPNPHESK
PWYYDGLSRGEAEDMLMRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVL
GTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSE
ISPSMPQRTVKALYDYKAKRNDELSFCRGALIHNVSKEPWGWWRGDYGTRIQQYFPSNYV
EDISTADVEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPHGKNQKQFVFILEPKKQGDP
PVEFATDKVEELFEWFQSIREITWKMDTKENSMKYWEKNQSIAIELSDLVVYCKPTSKAK
DNLENPDFREIRSFVETKADSVVRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWL
CGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEQYDPMPPENQRKILMTLS
VKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEI
YDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFC
EMQPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQL
YQEKCNRRLREKRVSNSRFYS
NT seq
3306 nt
NT seq
+upstream
nt +downstream
nt
atggctcacatccctgggagcagcaaaaggcagattccgggcccctcccaggctggggcg
tcacagccccttcttgtatcctctgtggccgggggtgtagtgtctgtcaccttgtgtccc
cagagagcctcgcagggtgtttggtggcagcttctgtggcttgtgttctgtctcaacacc
ctccttttccccgaggacagcaacaccgaccggccggacgcctctgcggtttacctgcac
gacttccagcgctttctcttacacgagcagcaggagctttgggctcaggatctgaacaaa
gtccgagagcggatgactaagttcatcgatgacaccatgagggagactgccgagcccttc
ttgtttgtcgatgagttcctcacgtacctcttttcgcgggagaacagcatctgggatgag
aagtacgacgtggtggacatgcaggacatgaacaaccccttgtcgcattactggatctcc
tcttcgcataacacgtacctcaccggcgaccagctgcggagcgagtcgtccacagaagcc
tacatccgctgcctgcgggcgggctgccgctgcattgagctggactgctgggatgggccc
gacgggaagcccatcatctaccatggctggacacggaccaccaagatcaagtttgatgac
gtcgtgcaggccatcaaagaccatgcctttgtcacctccagcttcccagtgatcctgtcc
atcgaggagcactgttgcgtggagcagcagcgccacatggcccgggtgttcaaggaggtg
tttggcgaccagctgctgacgaagcccacggaggcgagcgctgaccagctgccctcaccc
agccagctgcgggagaagttcatcatcaagcataagaagctgggtccccggggcgacgtg
gatgtcaacatggaggacaagaaggatgagcacaagcagcagggtgaactgtacatgtgg
gattccatcgaccagaaatggactcggcactactgtgccatcgccgatgccaagctgtcg
ttcagcgacgacattgaacagacagcagaagaggagctgccccaggatataccccccaca
gagctgcattttggggaggagtggttccacaagaaggtggagaagaggacgagtgccgag
aggctgctgcaggagtactgtgcggagacggggggcaaagacgggaccttcctggtgcga
gagagcaagaccttccccaacgactacaccctgtccttctggcggtctggccgggtccag
cactgccggatccggtccacgatggagggtgggaccatgaagtacttcctgaccgacaac
gtcacgttcaccagcatctatgacctcatccagcattaccgcgagacgcacctgcgctgc
accgagttcgagctccggctcaccgaccccgtgcccaaccccaacccccacgagtcaaag
ccgtggtactacgacgggctgagccgcggggaagcggaggacatgctaatgagggttccc
cgggacggcgccttcctcatccggaggcgagaaggcaccgactcgtacgccatcaccttc
agggccaggggcaaggtcaagcactgccgcatccaccgggacggccggcacttcgtgctg
gggacctcggcctacttcgagagcctcgtggagctcgtgagctactacgagaagcacgcg
ctgtaccggaagatgcggctgcgctaccccgtgacgccggagctcctggagcgctacaac
atggaaagagacatcaactccctttacgacgtcagcagaatgtatgtggatcccagtgaa
atcagcccctccatgcctcagagaactgtgaaagctctgtatgactacaaagccaagcgg
aacgatgagttgagcttctgccgtggggccctcattcacaacgtctccaaggagccctgg
ggctggtggagaggggactatggaaccagaatccagcagtacttcccgtccaattacgtc
gaggacatttcaacagccgacgtggaggagctggagaagcagattattgaggacaatccc
ttagggtctctctgtcggggaatattggatctcaacacctataacgtggtgaaagcgccc
cacgggaagaaccagaagcagttcgtgttcatcctggagcccaagaagcaaggcgacccg
ccggtggagttcgccacggacaaggtggaggagctcttcgagtggtttcagagtatccga
gagatcacgtggaagatggacaccaaggagaacagcatgaagtactgggagaagaaccag
tccatcgccatcgagctctcagacctggtcgtctactgcaagccaaccagcaaggccaag
gacaatctcgaaaaccccgacttccgagaaatccgctcctttgtggagacgaaggcagac
agtgtcgtcaggcagaaacccgtcgacctcctgaagtacaaccagaaaggcctgactcga
gtttaccccaagggacagagggtggactcctccaactacgacccctttcgcctctggctg
tgcggctcccagatggtggctctcaatttccagactccagataagtacatgcagatgaac
catgccttgttctcactcaatggtcgcacgggctacgtcctccagcccgagagcatgagg
tccgagcagtacgacccgatgcctcccgagaaccagagaaagatcttgatgaccctgtcg
gtcaaggttctcggggctcgccatctccccaaacttggacgaagtattgcgtgtcccttt
gtggaggtggaaatttgtggagctgagtatgacaacaacaagtttaagacaacagttgtg
aatgacaatggcctcagcccgatttgggctccaacacaggagaaagtgacctttgaaatt
tatgaccccaacctggcgtttctgcgttttgtcgtctacgaggaagatatgttcagtgat
cccaacttccttgcccacgccacttaccccatcaaaggaatcaaatcgggattcagatct
gttcctctgaagaacgggtacagtgaagacatcgagctggcttccctcctggttttctgt
gagatgcagccagtcctggagagcgaagaggagctctactcctcctgccgccagctgcga
aggcggcaggaagagctaaacaatcagctctttctgtacgacacgcaccagaacttgcgc
aatgccaaccgtgacgccctcgttaaggagttcaatgtcaacgagaaccagctccagctg
taccaggagaagtgcaaccggaggttgcgagagaagagagtcagcaacagcaggttttac
tcctag
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integrated database retrieval system
