KEGG   Mustela putorius furo (domestic ferret): 101672072
Entry
101672072         CDS       T07239                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01522  Endocrine resistance
mpuf04010  MAPK signaling pathway
mpuf04012  ErbB signaling pathway
mpuf04014  Ras signaling pathway
mpuf04024  cAMP signaling pathway
mpuf04068  FoxO signaling pathway
mpuf04071  Sphingolipid signaling pathway
mpuf04137  Mitophagy - animal
mpuf04140  Autophagy - animal
mpuf04141  Protein processing in endoplasmic reticulum
mpuf04210  Apoptosis
mpuf04215  Apoptosis - multiple species
mpuf04217  Necroptosis
mpuf04310  Wnt signaling pathway
mpuf04380  Osteoclast differentiation
mpuf04510  Focal adhesion
mpuf04530  Tight junction
mpuf04620  Toll-like receptor signaling pathway
mpuf04621  NOD-like receptor signaling pathway
mpuf04622  RIG-I-like receptor signaling pathway
mpuf04625  C-type lectin receptor signaling pathway
mpuf04657  IL-17 signaling pathway
mpuf04658  Th1 and Th2 cell differentiation
mpuf04659  Th17 cell differentiation
mpuf04660  T cell receptor signaling pathway
mpuf04664  Fc epsilon RI signaling pathway
mpuf04668  TNF signaling pathway
mpuf04722  Neurotrophin signaling pathway
mpuf04723  Retrograde endocannabinoid signaling
mpuf04728  Dopaminergic synapse
mpuf04750  Inflammatory mediator regulation of TRP channels
mpuf04910  Insulin signaling pathway
mpuf04912  GnRH signaling pathway
mpuf04914  Progesterone-mediated oocyte maturation
mpuf04917  Prolactin signaling pathway
mpuf04920  Adipocytokine signaling pathway
mpuf04926  Relaxin signaling pathway
mpuf04930  Type II diabetes mellitus
mpuf04931  Insulin resistance
mpuf04932  Non-alcoholic fatty liver disease
mpuf04933  AGE-RAGE signaling pathway in diabetic complications
mpuf04935  Growth hormone synthesis, secretion and action
mpuf04936  Alcoholic liver disease
mpuf05010  Alzheimer disease
mpuf05012  Parkinson disease
mpuf05016  Huntington disease
mpuf05017  Spinocerebellar ataxia
mpuf05020  Prion disease
mpuf05022  Pathways of neurodegeneration - multiple diseases
mpuf05132  Salmonella infection
mpuf05133  Pertussis
mpuf05135  Yersinia infection
mpuf05142  Chagas disease
mpuf05145  Toxoplasmosis
mpuf05152  Tuberculosis
mpuf05161  Hepatitis B
mpuf05162  Measles
mpuf05166  Human T-cell leukemia virus 1 infection
mpuf05167  Kaposi sarcoma-associated herpesvirus infection
mpuf05169  Epstein-Barr virus infection
mpuf05170  Human immunodeficiency virus 1 infection
mpuf05171  Coronavirus disease - COVID-19
mpuf05200  Pathways in cancer
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05210  Colorectal cancer
mpuf05212  Pancreatic cancer
mpuf05231  Choline metabolism in cancer
mpuf05415  Diabetic cardiomyopathy
mpuf05417  Lipid and atherosclerosis
mpuf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101672072 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101672072 (MAPK8)
   04012 ErbB signaling pathway
    101672072 (MAPK8)
   04014 Ras signaling pathway
    101672072 (MAPK8)
   04310 Wnt signaling pathway
    101672072 (MAPK8)
   04668 TNF signaling pathway
    101672072 (MAPK8)
   04068 FoxO signaling pathway
    101672072 (MAPK8)
   04071 Sphingolipid signaling pathway
    101672072 (MAPK8)
   04024 cAMP signaling pathway
    101672072 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101672072 (MAPK8)
   04137 Mitophagy - animal
    101672072 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    101672072 (MAPK8)
   04215 Apoptosis - multiple species
    101672072 (MAPK8)
   04217 Necroptosis
    101672072 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101672072 (MAPK8)
   04530 Tight junction
    101672072 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101672072 (MAPK8)
   04621 NOD-like receptor signaling pathway
    101672072 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    101672072 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    101672072 (MAPK8)
   04660 T cell receptor signaling pathway
    101672072 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    101672072 (MAPK8)
   04659 Th17 cell differentiation
    101672072 (MAPK8)
   04657 IL-17 signaling pathway
    101672072 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    101672072 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101672072 (MAPK8)
   04920 Adipocytokine signaling pathway
    101672072 (MAPK8)
   04912 GnRH signaling pathway
    101672072 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    101672072 (MAPK8)
   04917 Prolactin signaling pathway
    101672072 (MAPK8)
   04926 Relaxin signaling pathway
    101672072 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    101672072 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    101672072 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    101672072 (MAPK8)
   04722 Neurotrophin signaling pathway
    101672072 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101672072 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101672072 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101672072 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    101672072 (MAPK8)
   05231 Choline metabolism in cancer
    101672072 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101672072 (MAPK8)
   05212 Pancreatic cancer
    101672072 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101672072 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    101672072 (MAPK8)
   05161 Hepatitis B
    101672072 (MAPK8)
   05171 Coronavirus disease - COVID-19
    101672072 (MAPK8)
   05162 Measles
    101672072 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101672072 (MAPK8)
   05169 Epstein-Barr virus infection
    101672072 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101672072 (MAPK8)
   05135 Yersinia infection
    101672072 (MAPK8)
   05133 Pertussis
    101672072 (MAPK8)
   05152 Tuberculosis
    101672072 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101672072 (MAPK8)
   05142 Chagas disease
    101672072 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101672072 (MAPK8)
   05012 Parkinson disease
    101672072 (MAPK8)
   05016 Huntington disease
    101672072 (MAPK8)
   05017 Spinocerebellar ataxia
    101672072 (MAPK8)
   05020 Prion disease
    101672072 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    101672072 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101672072 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    101672072 (MAPK8)
   05415 Diabetic cardiomyopathy
    101672072 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101672072 (MAPK8)
   04936 Alcoholic liver disease
    101672072 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    101672072 (MAPK8)
   04931 Insulin resistance
    101672072 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101672072 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101672072 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mpuf01001]
    101672072 (MAPK8)
Enzymes [BR:mpuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101672072 (MAPK8)
Protein kinases [BR:mpuf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101672072 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH DUF530
Other DBs
NCBI-GeneID: 101672072
NCBI-ProteinID: XP_004765888
Ensembl: ENSMPUG00000009129
UniProt: A0A8U0US06
LinkDB
Position
Unknown
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagagattggagattctacattt
acagtcttgaaacgatatcagaatttaaaacctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccggcca
tttcagaaccagactcatgctaaacgggcttacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgagagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatcgtggtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacag
cttggaacaccatgccctgaattcatgaagaaactacagccaacagtaaggacttatgtt
gaaaacagacctaaatatgctggatatagctttgagaaactcttccccgatgtacttttc
ccagctgactcagaacacaacaaacttaaagccagtcaggcaagggatttgttatccaaa
atgctggtaattgatgcatctaaaaggatttctgtagatgaagctctccagcacccatat
atcaatgtctggtatgatccttctgaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacatacaatagaagaatggaaagagttgatatacaaagaagtt
atggacttggaggagagaaccaagaatggagttataaggggacagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccgactttggcctcagatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga

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